CS255894B2 - Process for preparing new derivatives of phenylacetonitrile - Google Patents

Process for preparing new derivatives of phenylacetonitrile Download PDF

Info

Publication number
CS255894B2
CS255894B2 CS856522A CS652285A CS255894B2 CS 255894 B2 CS255894 B2 CS 255894B2 CS 856522 A CS856522 A CS 856522A CS 652285 A CS652285 A CS 652285A CS 255894 B2 CS255894 B2 CS 255894B2
Authority
CS
Czechoslovakia
Prior art keywords
och
methyl
cyano
phenoxy
methoxy
Prior art date
Application number
CS856522A
Other languages
Czech (cs)
English (en)
Other versions
CS652285A2 (en
Inventor
Herbert Leinert
Wolfgang Kampe
Klaus Strein
Bernd Mueller-Beckmann
Wolfgang Bartsch
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of CS652285A2 publication Critical patent/CS652285A2/cs
Publication of CS255894B2 publication Critical patent/CS255894B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
CS856522A 1984-09-12 1985-09-12 Process for preparing new derivatives of phenylacetonitrile CS255894B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843433383 DE3433383A1 (de) 1984-09-12 1984-09-12 Neue phenyl-acetonitril-derivate

Publications (2)

Publication Number Publication Date
CS652285A2 CS652285A2 (en) 1987-07-16
CS255894B2 true CS255894B2 (en) 1988-03-15

Family

ID=6245162

Family Applications (1)

Application Number Title Priority Date Filing Date
CS856522A CS255894B2 (en) 1984-09-12 1985-09-12 Process for preparing new derivatives of phenylacetonitrile

Country Status (16)

Country Link
US (1) US4612313A (da)
EP (1) EP0175249A3 (da)
JP (1) JPS6185355A (da)
AU (1) AU562730B2 (da)
CA (1) CA1248533A (da)
CS (1) CS255894B2 (da)
DD (1) DD237504A5 (da)
DE (1) DE3433383A1 (da)
DK (1) DK413685A (da)
ES (1) ES8604861A1 (da)
FI (1) FI853343L (da)
GR (1) GR852167B (da)
HU (1) HU195644B (da)
IL (1) IL76327A (da)
SU (1) SU1508956A3 (da)
ZA (1) ZA856942B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4612329A (en) * 1984-10-17 1986-09-16 Hokuriku Pharmaceutical Co., Ltd. Pharmaceutical alpha-aminoalkyl-alpha-alkylphenylacetonitriles
DE3642331A1 (de) * 1986-12-11 1988-06-23 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel
GB8717068D0 (en) * 1987-07-20 1987-08-26 Fujisawa Pharmaceutical Co Nitric ester derivative
NL9001955A (nl) * 1990-09-05 1992-04-01 Cedona Pharm Bv Nieuwe thiazolidinederivaten.
US6263940B1 (en) 1999-04-21 2001-07-24 Axon Corporation In-line continuous feed sleeve labeling machine and method
TW200821303A (en) * 2006-08-08 2008-05-16 Speedel Experimenta Ag Organic compounds
JP5421908B2 (ja) * 2007-06-20 2014-02-19 マイルストーン ファーマシューティカルズ インコーポレーテッド 短時間作用型フェニルアルキルアミンカルシウムチャネルブロッカーおよびその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1154810B (de) 1961-04-01 1963-09-26 Knoll Ag Verfahren zur Herstellung basisch substituierter Phenylacetonitrile
US4340603A (en) * 1980-08-13 1982-07-20 Interx Research Corporation Novel inotropic prodrugs
DE3144150A1 (de) * 1981-04-10 1982-12-09 Basf Ag, 6700 Ludwigshafen (omega)-cyan-1,(omega)-diphenyl-azaalkan-derivate, ihre herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
GR852167B (da) 1986-01-03
ZA856942B (en) 1986-05-28
SU1508956A3 (ru) 1989-09-15
CS652285A2 (en) 1987-07-16
FI853343A0 (fi) 1985-08-30
AU562730B2 (en) 1987-06-18
US4612313A (en) 1986-09-16
AU4709985A (en) 1986-03-20
DK413685D0 (da) 1985-09-11
DD237504A5 (de) 1986-07-16
FI853343L (fi) 1986-03-13
IL76327A (en) 1989-06-30
ES546908A0 (es) 1986-03-16
ES8604861A1 (es) 1986-03-16
HUT38302A (en) 1986-05-28
EP0175249A2 (de) 1986-03-26
JPS6185355A (ja) 1986-04-30
CA1248533A (en) 1989-01-10
EP0175249A3 (de) 1987-08-19
DK413685A (da) 1986-03-13
HU195644B (en) 1988-06-28
IL76327A0 (en) 1986-01-31
DE3433383A1 (de) 1986-03-20

Similar Documents

Publication Publication Date Title
US4567264A (en) Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
US4065584A (en) Sulphur containing arylamine derivatives
JP2771328B2 (ja) N―フェニルアルキル置換α―アミノカルボキシアミド誘導体およびその製造方法
US6660756B2 (en) N-phenpropylcyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase
JPS6148494B2 (da)
JPH075539B2 (ja) 置換スルホンアミドベンズアミド及びその製法
NZ527012A (en) N-phenpropylcyclopentyl-substituted glutaramide derivatives as NEP inhibitors for FSAD
JP2722250B2 (ja) 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
SK1142003A3 (en) Carboxamide compounds and their use as antagonists of a human 11CBY receptor
JPS6259101B2 (da)
JPH0123462B2 (da)
EP2238105B1 (en) Novel compounds as vanilloid receptor antagonists
DK163181B (da) Analogifremgangsmaade til fremstilling af n,n'-di(arylalkylen)alkylendiaminer eller farmaceutisk acceptable salte deraf
EP0344577B1 (en) Butenoic or propenoic acid derivatives
CS255894B2 (en) Process for preparing new derivatives of phenylacetonitrile
US4246267A (en) Aminopiperidines, their production and the pharmaceutical compositions incorporating them
HU203338B (en) Process for producing thiofene derivatives
US4840967A (en) Carbamate or urea derivatives, their preparation and pharmaceutical compositions comprising them
US4977153A (en) 3-aminopropyloxyphenyl derivatives, pharmaceutical compositions containing them and method for the therapy of diseases
EP0424194B1 (en) Benzanilide derivatives and their use as anti-atherosclerotic agents
HU212415B (en) Process for producing new cyclic oxym derivatives and pharmaceutical compositions containing them as active components
KR0122884B1 (ko) 3,3-디페닐아크릴산 아미드의 제조방법
US4914126A (en) Aromatic amines
US4912110A (en) Antidepressive substituted phenylpiperazine compounds
US5234934A (en) Aminopropanol derivatives, process for their preparation and pharmaceutical compositions comprising the same