CS249455B1 - N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation - Google Patents
N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation Download PDFInfo
- Publication number
- CS249455B1 CS249455B1 CS85516A CS51685A CS249455B1 CS 249455 B1 CS249455 B1 CS 249455B1 CS 85516 A CS85516 A CS 85516A CS 51685 A CS51685 A CS 51685A CS 249455 B1 CS249455 B1 CS 249455B1
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- fluoro
- chloro
- enzo
- piperazino
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS85516A CS249455B1 (en) | 1985-01-24 | 1985-01-24 | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation |
CA000498881A CA1238047A (en) | 1985-01-24 | 1986-01-02 | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11- dihydrodibenzo (b,f)thiepins, their acid addition salts and processes for the preparation thereof |
DK30586A DK30586A (da) | 1985-01-24 | 1986-01-21 | N-substituerede 2-chlor-7-fluor-10-piperzino-10,11-dihydrodibenzo(b,f)thiepiner, deres syreadditionssalte og fremgangsmaader til deres fremstilling |
EP86300389A EP0189310A3 (en) | 1985-01-24 | 1986-01-21 | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo (b,f) thiepins, their acid addition salts and processes for the preparation thereof |
FI860329A FI860329A (fi) | 1985-01-24 | 1986-01-23 | N-substituerade 2-klor-7-fluor-10 -piperazino-10,11-dihydrodibenzo(b,f)tiepiner, deras syraadditionssalter och foerfaranden foer framstaellning av dem. |
JP61011194A JPS61204181A (ja) | 1985-01-24 | 1986-01-23 | N−置換された2−クロロ−7−フルオロ−10−ピペラジノ−10,11−ジヒドロジベンゾ〔b,f〕チエピン,酸付加塩類及びそれらの調製法 |
US06/821,992 US4678788A (en) | 1985-01-24 | 1986-01-24 | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo (B,F) thiepins and acid addition salts thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS85516A CS249455B1 (en) | 1985-01-24 | 1985-01-24 | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
CS249455B1 true CS249455B1 (en) | 1987-03-12 |
Family
ID=5337371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CS85516A CS249455B1 (en) | 1985-01-24 | 1985-01-24 | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation |
Country Status (7)
Country | Link |
---|---|
US (1) | US4678788A (ja) |
EP (1) | EP0189310A3 (ja) |
JP (1) | JPS61204181A (ja) |
CA (1) | CA1238047A (ja) |
CS (1) | CS249455B1 (ja) |
DK (1) | DK30586A (ja) |
FI (1) | FI860329A (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992012133A2 (en) * | 1991-01-08 | 1992-07-23 | E.I. Du Pont De Nemours And Company | Arthropodicidal carboxanilides |
US5538965A (en) * | 1993-12-23 | 1996-07-23 | Allelix Biopharmaceuticals Inc. | Dopamine receptor ligands |
AR043880A1 (es) * | 2003-04-22 | 2005-08-17 | Solvay Pharm Gmbh | Mesilato acido de 4-(4.trans-hidroxiciclohexil) amino-2-fenil-7h-pirrolo (2,3-d) pirimidina y sus formas polimorfas |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE757868A (fr) * | 1969-10-25 | 1971-04-01 | Spofa Usines Pharma Reunies | Procede de preparation de nouvelles 10-piperazino-10,11-dihydrodibenzo/b,f,/thiepines et de leurs sels, ainsi que les produits obtenus |
BE757926A (fr) * | 1969-10-25 | 1971-04-01 | Spofa Usines Pharma Reunies | Procede de preparation de nouvelles amidoximes de la serie des 10-piperazino-10,11-dihydrodibenzo/b,f/thiepines et leurs sels, ainsique les produits obtenus |
DD113545A5 (ja) * | 1973-03-30 | 1975-06-12 | ||
DE2704934A1 (de) * | 1976-02-17 | 1977-08-18 | Sandoz Ag | Organische verbindungen, ihre herstellung und verwendung |
CS196893B1 (en) * | 1977-12-22 | 1980-04-30 | Miroslav Protiva | 3-fluor-10-piperazino-8-substituted 10,11-dihydro-dibenzothiepines |
-
1985
- 1985-01-24 CS CS85516A patent/CS249455B1/cs unknown
-
1986
- 1986-01-02 CA CA000498881A patent/CA1238047A/en not_active Expired
- 1986-01-21 EP EP86300389A patent/EP0189310A3/en not_active Withdrawn
- 1986-01-21 DK DK30586A patent/DK30586A/da not_active Application Discontinuation
- 1986-01-23 FI FI860329A patent/FI860329A/fi not_active IP Right Cessation
- 1986-01-23 JP JP61011194A patent/JPS61204181A/ja active Pending
- 1986-01-24 US US06/821,992 patent/US4678788A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK30586A (da) | 1986-07-25 |
CA1238047A (en) | 1988-06-14 |
US4678788A (en) | 1987-07-07 |
FI860329A (fi) | 1986-07-25 |
JPS61204181A (ja) | 1986-09-10 |
DK30586D0 (da) | 1986-01-21 |
EP0189310A3 (en) | 1987-05-20 |
EP0189310A2 (en) | 1986-07-30 |
FI860329A0 (fi) | 1986-01-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HU211575A9 (en) | 2-methyl-thieno-benzodiazepine | |
NO162384B (no) | Analogifremgangsmaate til fremstilling av 1-hetero-aryl-4-(2,5-pyrrolidinion-1-yl)-alkyl)piperazinderivater. | |
EP0988306A1 (de) | 3-substituierte 3,4-dihydro-thieno 2,3-d]pyrimidin-derivate, ihre herstellung und verwendung | |
DE19636769A1 (de) | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung | |
EP0183994B1 (de) | Tricyclische Pyridonderivate | |
HU190984B (en) | Process for producing new furo-, thieno- or pinolo-azepin derivatives | |
US3491103A (en) | Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes | |
KR20120101551A (ko) | Mglur5 수용체의 알로스테릭 조절자로서 바이사이클릭 티아졸 | |
NO772473L (no) | Fremgangsm}te ved fremstilling av nye thieno (2,3-c) og (3,2-c) pyridiner | |
DE60204582T2 (de) | Neue heteroaromatische amidderivate von 3beta aminoazabicyclooctanen, verfahren zu ihrer herstellung und ihre therapeutische verwendung | |
CS207619B2 (en) | Method of making the new derivatives of 5,11-dihydro-6h-pyrido 2,3-b 1,4 benzodiazepin-6-on | |
NO153495B (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive morfantridin-derivater. | |
CS249455B1 (en) | N-substituted 2-chloro-7-fluoro-10-piperazino-10,11-dihydrodibenzo(b,f)thiepines and their salts and method of their preparation | |
CZ290678B6 (cs) | 3-Substituované 3,4,5,7-tetrahydropyrrolo[3´,4´: 4,5]thieno[2,3-d]pyrimidinové deriváty, způsob jejich přípravy a použití | |
EP1023296B1 (de) | 3-SUBSTITUIERTE PYRIDO 3',4':4,5] THIENO 2,3-d] PYRIMIDIN-DERIVATE, IHRE HERSTELLUNG UND VERWENDUNG | |
Huckle et al. | 4-Amino-2, 3, 4, 5-tetrahydro-1-benzoxepin-5-ols, 4-amino-2, 3, 4, 5-tetrahydro-1-benzothiepin-5-ols, and related compounds | |
US3464983A (en) | 4h-benzo(4,5)cyclohepta(1,2-b)thiophenes | |
US4511569A (en) | Tricyclic lactams and derivatives useful in increasing cardiac contractility | |
PL90057B1 (en) | Piperdine derivatives[au6900774a] | |
Remy et al. | A comparison of the antiserotonin, antihistamine, and anticholinergic activity of cyproheptadine with analogs having furan nuclei fused to the 10, 11-vinylene bridge | |
CA2958331C (en) | New pyridopyrimidines derivatives compounds | |
EP1256583B1 (fr) | Dérivés de pyrimidin-4-ones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent | |
KR20030010756A (ko) | 2-아미노알킬티에노[2,3-d]피리미딘 | |
DK158311B (da) | Analogifremgangsmaade til fremstilling af hexahydrobenzopyrano(3,2-c)pyridiner | |
NO158462B (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive (1,2)-kondenserte 1,4-benzodiazepinforbindelser. |