CS248028B2 - Production method of 2-(2-thieny)-a 2-(3-thienyl)ethylanes - Google Patents

Production method of 2-(2-thieny)-a 2-(3-thienyl)ethylanes Download PDF

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Publication number
CS248028B2
CS248028B2 CS824895A CS489582A CS248028B2 CS 248028 B2 CS248028 B2 CS 248028B2 CS 824895 A CS824895 A CS 824895A CS 489582 A CS489582 A CS 489582A CS 248028 B2 CS248028 B2 CS 248028B2
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Czechoslovakia
Prior art keywords
formula
thienyl
compound
ppm
alkyl
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CS824895A
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Czech (cs)
English (en)
Inventor
Isaac Chekroun
Alain Hevmes
Original Assignee
Sanofi Sa
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Publication of CS248028B2 publication Critical patent/CS248028B2/cs

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32Esters thereof
    • C07F9/3205Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211Esters of acyclic saturated acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006Esters of acyclic acids which can have further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40Esters thereof
    • C07F9/4003Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056Esters of arylalkanephosphonic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • C07F9/5004Acyclic saturated phosphines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Saccharide Compounds (AREA)
  • Liquid Deposition Of Substances Of Which Semiconductor Devices Are Composed (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS824895A 1981-06-30 1982-06-29 Production method of 2-(2-thieny)-a 2-(3-thienyl)ethylanes CS248028B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8113062A FR2508453A1 (fr) 1981-06-30 1981-06-30 Procede de preparation de derives des (thienyl-2)- et thienyl-3)-2 ethylamines et produits ainsi obtenus

Publications (1)

Publication Number Publication Date
CS248028B2 true CS248028B2 (en) 1987-01-15

Family

ID=9260129

Family Applications (1)

Application Number Title Priority Date Filing Date
CS824895A CS248028B2 (en) 1981-06-30 1982-06-29 Production method of 2-(2-thieny)-a 2-(3-thienyl)ethylanes

Country Status (24)

Country Link
US (1) US4482718A (de)
EP (1) EP0068978B1 (de)
JP (1) JPS5810574A (de)
KR (1) KR840000536A (de)
AT (1) ATE21897T1 (de)
AU (1) AU566802B2 (de)
CA (1) CA1205810A (de)
CS (1) CS248028B2 (de)
DD (1) DD206377A5 (de)
DE (1) DE3273015D1 (de)
DK (1) DK286682A (de)
ES (1) ES514221A0 (de)
FI (1) FI822315L (de)
FR (1) FR2508453A1 (de)
GR (1) GR76496B (de)
HU (1) HU194860B (de)
IE (1) IE53228B1 (de)
IL (1) IL65980A (de)
NO (1) NO155136C (de)
NZ (1) NZ200852A (de)
PT (1) PT75152B (de)
SU (1) SU1148563A3 (de)
YU (1) YU143382A (de)
ZA (1) ZA824624B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508454A1 (fr) * 1981-06-30 1982-12-31 Sanofi Sa Procede de preparation de derives des (thienyl-2)- et (thienyl-3)-2 ethylamines et produits ainsi obtenus
CA1242718A (en) * 1983-11-21 1988-10-04 John R. Carson Acetylene derivatives and methods for the treatment of hypertension and angina
CA1292747C (en) * 1983-11-21 1991-12-03 John Robert Carson Aralykyl (arylethynyl) aralkyl amines and their use as vasodilators and antihypertensives
FR2622191B1 (fr) * 1987-10-22 1991-06-21 Sanofi Sa Procede de preparation de la n-(chloro-2 benzyl)-2 ethylamine et produits intermediaires dans cette preparation
JPH0283380A (ja) * 1988-09-21 1990-03-23 Kotobuki Seiyaku Kk 新規ジアミン誘導体、抗不整脈剤及びその製法
US4900539A (en) * 1988-12-22 1990-02-13 The United States Of America As Represented By The United States Department Of Energy Radiohalogenated thienylethylamine derivatives for evaluating local cerebral blood flow
WO1993003025A1 (en) * 1991-08-09 1993-02-18 Yoshitomi Pharmaceutical Industries, Ltd. Thiophene compound
PL2744801T3 (pl) * 2011-08-17 2017-10-31 Shan Dong Luye Pharm Co Ltd 5,6,7,8-tetrahydro-6-[n,n-bis[(2-tienylo)etylo]]amino-1-naftol i sposób jego przygotowania i zastosowania

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2983729A (en) * 1958-04-30 1961-05-09 Monsanto Chemicals Preparation of 5-halothienyl amines
FR2300090A1 (fr) * 1975-02-07 1976-09-03 Parcor Procede de preparation de derives de la thienopyridine
US4127580A (en) * 1975-02-07 1978-11-28 Parcor Process for the preparation of thieno-pyridine derivatives
FR2315274A1 (fr) * 1975-06-27 1977-01-21 Parcor Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications
IT1082336B (it) * 1977-01-27 1985-05-21 Medea Res Srl Processo per la preparazione della 5.2.clorobenzil.4 5 6 7.tetraidro tien 3 2.c.piridina

Also Published As

Publication number Publication date
FI822315A7 (fi) 1982-12-31
SU1148563A3 (ru) 1985-03-30
FR2508453A1 (fr) 1982-12-31
EP0068978B1 (de) 1986-09-03
ES8305349A1 (es) 1983-04-01
YU143382A (en) 1984-12-31
US4482718A (en) 1984-11-13
NO155136B (no) 1986-11-10
NO822224L (no) 1983-01-03
EP0068978A1 (de) 1983-01-05
PT75152A (fr) 1982-07-01
FI822315A0 (fi) 1982-06-29
DE3273015D1 (en) 1986-10-09
KR840000536A (ko) 1984-02-25
NZ200852A (en) 1985-09-13
AU566802B2 (en) 1987-10-29
IE821310L (en) 1982-12-30
NO155136C (no) 1987-02-18
DD206377A5 (de) 1984-01-25
IL65980A0 (en) 1982-09-30
JPS5810574A (ja) 1983-01-21
GR76496B (de) 1984-08-10
CA1205810A (en) 1986-06-10
ATE21897T1 (de) 1986-09-15
FI822315L (fi) 1982-12-31
PT75152B (fr) 1984-05-29
IE53228B1 (en) 1988-09-14
ZA824624B (en) 1983-04-27
AU8475582A (en) 1983-01-06
IL65980A (en) 1985-12-31
HU194860B (en) 1988-03-28
FR2508453B1 (de) 1983-12-23
DK286682A (da) 1982-12-31
ES514221A0 (es) 1983-04-01

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