CS241491A3 - Novel conjugate of therapeutically usable compounds with a carrier - Google Patents
Novel conjugate of therapeutically usable compounds with a carrier Download PDFInfo
- Publication number
- CS241491A3 CS241491A3 CS912414A CS241491A CS241491A3 CS 241491 A3 CS241491 A3 CS 241491A3 CS 912414 A CS912414 A CS 912414A CS 241491 A CS241491 A CS 241491A CS 241491 A3 CS241491 A3 CS 241491A3
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- conjugate
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- A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
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- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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GB909017024A GB9017024D0 (en) | 1990-08-03 | 1990-08-03 | New linker for bioactive agents |
Publications (1)
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CS241491A3 true CS241491A3 (en) | 1992-02-19 |
Family
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Application Number | Title | Priority Date | Filing Date |
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CS912414A CS241491A3 (en) | 1990-08-03 | 1991-08-02 | Novel conjugate of therapeutically usable compounds with a carrier |
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US (2) | US5387578A (zh) |
EP (1) | EP0495053B1 (zh) |
JP (1) | JP3169222B2 (zh) |
KR (1) | KR920702234A (zh) |
CN (1) | CN1058598A (zh) |
AT (1) | ATE135919T1 (zh) |
AU (1) | AU650900B2 (zh) |
CA (1) | CA2067184C (zh) |
CS (1) | CS241491A3 (zh) |
DE (1) | DE69118350T2 (zh) |
DK (1) | DK0495053T3 (zh) |
ES (1) | ES2088013T3 (zh) |
FI (1) | FI100697B (zh) |
GB (1) | GB9017024D0 (zh) |
GR (1) | GR3019449T3 (zh) |
HU (1) | HUT61898A (zh) |
IE (1) | IE76467B1 (zh) |
IL (2) | IL98986A (zh) |
MY (1) | MY106526A (zh) |
NO (1) | NO921287L (zh) |
NZ (1) | NZ239165A (zh) |
PH (1) | PH31048A (zh) |
PT (1) | PT98545B (zh) |
RU (1) | RU2116087C1 (zh) |
TW (1) | TW211572B (zh) |
WO (1) | WO1992002255A1 (zh) |
YU (1) | YU48441B (zh) |
ZA (1) | ZA916025B (zh) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
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US5439936A (en) * | 1989-10-03 | 1995-08-08 | The Regents Of The University Of California | Method of treating certain tumors using illudin analogs |
GB9017024D0 (en) * | 1990-08-03 | 1990-09-19 | Erba Carlo Spa | New linker for bioactive agents |
DE4236237A1 (de) * | 1992-10-27 | 1994-04-28 | Behringwerke Ag | Prodrugs, ihre Herstellung und Verwendung als Arzneimittel |
GB9309663D0 (en) * | 1993-05-11 | 1993-06-23 | Erba Carlo Spa | Biologically active compounds |
GB9416007D0 (en) * | 1994-08-08 | 1994-09-28 | Erba Carlo Spa | Anthracyclinone derivatives |
US5783178A (en) * | 1994-11-18 | 1998-07-21 | Supratek Pharma. Inc. | Polymer linked biological agents |
US6030941A (en) * | 1996-05-01 | 2000-02-29 | Avi Biopharma, Inc. | Polymer composition for delivering substances in living organisms |
CA2252706A1 (en) * | 1996-05-01 | 1997-11-06 | Antivirals Inc. | Polypeptide conjugates for transporting substances across cell membranes |
US5932553A (en) * | 1996-07-18 | 1999-08-03 | The Regents Of The University Of California | Illudin analogs useful as antitumor agents |
US5723632A (en) | 1996-08-08 | 1998-03-03 | Mgi Pharma, Inc. | Total synthesis of antitumor acylfulvenes |
DE19636889A1 (de) | 1996-09-11 | 1998-03-12 | Felix Dr Kratz | Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel |
AU7124598A (en) * | 1997-04-18 | 1998-11-13 | Access Pharmaceuticals, Inc. | Polymer-platinum compounds |
US5965118A (en) * | 1997-04-18 | 1999-10-12 | Access Pharmaceuticals, Inc. | Polymer-platinum compounds |
US6306993B1 (en) * | 1997-05-21 | 2001-10-23 | The Board Of Trustees Of The Leland Stanford, Jr. University | Method and composition for enhancing transport across biological membranes |
US6531230B1 (en) * | 1998-01-13 | 2003-03-11 | 3M Innovative Properties Company | Color shifting film |
US6025328A (en) | 1998-02-20 | 2000-02-15 | The Regents Of The University Of California | Antitumor agents |
US7141603B2 (en) * | 1999-02-19 | 2006-11-28 | The Regents Of The University California | Antitumor agents |
ES2222719T3 (es) * | 1998-07-30 | 2005-02-01 | Oakville Trading Hong Kong Limited | Procedimiento para preparar conjugados reticulados solubles en agua. |
US6706892B1 (en) | 1999-09-07 | 2004-03-16 | Conjuchem, Inc. | Pulmonary delivery for bioconjugation |
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1990
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