CS238901B1 - Processing of 4-oxo-4h-pyrido/1,2-a/pyrimidine derivatives - Google Patents

Processing of 4-oxo-4h-pyrido/1,2-a/pyrimidine derivatives Download PDF

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Publication number
CS238901B1
CS238901B1 CS785417A CS541778A CS238901B1 CS 238901 B1 CS238901 B1 CS 238901B1 CS 785417 A CS785417 A CS 785417A CS 541778 A CS541778 A CS 541778A CS 238901 B1 CS238901 B1 CS 238901B1
Authority
CS
Czechoslovakia
Prior art keywords
ethyl
oxo
methyl
formula
pyrido
Prior art date
Application number
CS785417A
Other languages
Czech (cs)
English (en)
Other versions
CS541778A1 (en
Inventor
Jouzsef Knoll
Zoltan Meszaros
Istvan Hermecz
Ferenc Fueloep
Gabor Bernath
Sandor Virag
Gabor Nagy
Peter Szentmiklosi
Original Assignee
Jouzsef Knoll
Zoltan Meszaros
Istvan Hermecz
Ferenc Fueloep
Gabor Bernath
Sandor Virag
Gabor Nagy
Peter Szentmiklosi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jouzsef Knoll, Zoltan Meszaros, Istvan Hermecz, Ferenc Fueloep, Gabor Bernath, Sandor Virag, Gabor Nagy, Peter Szentmiklosi filed Critical Jouzsef Knoll
Publication of CS541778A1 publication Critical patent/CS541778A1/cs
Publication of CS238901B1 publication Critical patent/CS238901B1/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS785417A 1977-08-19 1978-08-18 Processing of 4-oxo-4h-pyrido/1,2-a/pyrimidine derivatives CS238901B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1765A HU178910B (en) 1977-08-19 1977-08-19 Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines

Publications (2)

Publication Number Publication Date
CS541778A1 CS541778A1 (en) 1985-05-15
CS238901B1 true CS238901B1 (en) 1985-12-16

Family

ID=10994667

Family Applications (1)

Application Number Title Priority Date Filing Date
CS785417A CS238901B1 (en) 1977-08-19 1978-08-18 Processing of 4-oxo-4h-pyrido/1,2-a/pyrimidine derivatives

Country Status (22)

Country Link
US (2) US4219649A (de)
JP (1) JPS5448795A (de)
AT (1) AT368156B (de)
AU (1) AU518364B2 (de)
BE (1) BE869832A (de)
CA (1) CA1152989A (de)
CH (1) CH637541A5 (de)
CS (1) CS238901B1 (de)
DD (1) DD138320A5 (de)
DE (1) DE2835004A1 (de)
DK (1) DK160045C (de)
ES (1) ES473181A1 (de)
FI (1) FI66864C (de)
FR (1) FR2416892A1 (de)
GB (1) GB2006187B (de)
GR (1) GR64913B (de)
HU (1) HU178910B (de)
IL (1) IL55338A (de)
NL (1) NL7808570A (de)
SE (1) SE435383B (de)
SU (1) SU906378A3 (de)
YU (1) YU40985B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
HU179143B (en) * 1977-12-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 9-hydroxy-groops-containing 6,7-dihydro-pyrido-square bracket-1,2-a-square bracket closed-pyrimidin derivatives and esters thereof
FR2449689A1 (fr) * 1979-02-20 1980-09-19 Logeais Labor Jacques Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
AU527931B2 (en) 1979-05-08 1983-03-31 Farmitalia Carlo Erba S.P.A. Substituted pyrido(1,2-a)pyrimidines
PL129612B1 (en) * 1980-07-24 1984-05-31 Rhone Poulenc Ind Process for preparing novel derivatives of 2,3,6,7-tetrahydrothiazole/3,2-a/pirymidin-5-one
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
CA1211111A (en) * 1982-02-15 1986-09-09 Isao Yanagisawa Process for preparing novel pyrimidone compounds
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
WO1991016894A1 (en) * 1990-05-02 1991-11-14 Abbott Laboratories Quinolizinone type compounds
DE10050661A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine
DE10050662A1 (de) * 2000-10-13 2002-04-18 Gruenenthal Gmbh Substituierte 3,4-Dihydro-pyrido[1,2-a]pyrimidine
DE20202183U1 (de) 2002-02-01 2002-06-06 Kretzschmar Michael Baukasten
CA2500952C (en) * 2002-10-04 2011-04-26 Prana Biotechnology Limited Neurologically-active compounds
NZ590271A (en) * 2006-04-14 2011-12-22 Prana Biotechnology Ltd 9-hydroxy-3-substituted-4H-pyrido[1,2-a]pyrimidin-4-ones and 9-hydroxy-3-substituted-4H-pyrido[1,2-a]pyrimidin-4-thiones
US7955155B2 (en) 2007-07-09 2011-06-07 Mega Brands International Magnetic and electronic toy construction systems and elements
JP5649304B2 (ja) * 2007-11-13 2015-01-07 国立大学法人 東京大学 クオラムセンシング阻害剤
CN102105470B (zh) * 2008-06-17 2014-06-04 韩国巴斯德研究所 作为抗结核病药的吡啶并嘧啶化合物
CN111961050A (zh) * 2014-12-02 2020-11-20 普拉纳生物技术有限公司 4H-吡啶并[1,2-a]嘧啶-4-酮化合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT299212B (de) * 1966-11-02 1972-06-12 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU169230B (de) * 1972-03-29 1976-10-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168014B (de) * 1973-03-30 1976-02-28
HU168541B (de) * 1973-11-24 1976-05-28
US4022897A (en) * 1974-03-04 1977-05-10 E. R. Squibb & Sons, Inc. CNS active compounds
US3898224A (en) * 1974-09-09 1975-08-05 Squibb & Sons Inc 1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3935197A (en) * 1975-05-16 1976-01-27 E. R. Squibb & Sons, Inc. 2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones

Also Published As

Publication number Publication date
JPS626554B2 (de) 1987-02-12
DK160045B (da) 1991-01-21
US4219649A (en) 1980-08-26
CH637541A5 (de) 1983-08-15
FI66864C (fi) 1984-12-10
ES473181A1 (es) 1979-04-01
SE7808770L (sv) 1979-02-20
HU178910B (en) 1982-07-28
GB2006187B (en) 1982-10-06
FI782527A (fi) 1979-02-20
YU40985B (en) 1986-10-31
BE869832A (fr) 1978-12-18
AT368156B (de) 1982-09-27
GB2006187A (en) 1979-05-02
ATA585278A (de) 1982-01-15
AU3900978A (en) 1980-02-21
DD138320A5 (de) 1979-10-24
DK160045C (da) 1991-06-10
DE2835004A1 (de) 1979-03-01
AU518364B2 (en) 1981-09-24
IL55338A0 (en) 1978-10-31
US4291036A (en) 1981-09-22
FR2416892A1 (fr) 1979-09-07
SU906378A3 (ru) 1982-02-15
NL7808570A (nl) 1979-02-21
FR2416892B1 (de) 1983-11-18
DK367478A (da) 1979-02-20
IL55338A (en) 1985-10-31
SE435383B (sv) 1984-09-24
JPS5448795A (en) 1979-04-17
FI66864B (fi) 1984-08-31
CS541778A1 (en) 1985-05-15
DE2835004C2 (de) 1989-06-29
CA1152989A (en) 1983-08-30
YU196678A (en) 1983-10-31
GR64913B (en) 1980-06-09

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