CS232735B2 - Method of making cephalosporine derivatives - Google Patents
Method of making cephalosporine derivatives Download PDFInfo
- Publication number
- CS232735B2 CS232735B2 CS826505A CS650582A CS232735B2 CS 232735 B2 CS232735 B2 CS 232735B2 CS 826505 A CS826505 A CS 826505A CS 650582 A CS650582 A CS 650582A CS 232735 B2 CS232735 B2 CS 232735B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- group
- formula
- thieno
- pyridinium
- cephem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/40—Radicals substituted by oxygen atoms
- C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30035781A | 1981-09-08 | 1981-09-08 | |
| US34062882A | 1982-01-19 | 1982-01-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CS650582A2 CS650582A2 (en) | 1984-06-18 |
| CS232735B2 true CS232735B2 (en) | 1985-02-14 |
Family
ID=26971737
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS826505A CS232735B2 (en) | 1981-09-08 | 1982-09-08 | Method of making cephalosporine derivatives |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0074268A3 (xx) |
| KR (1) | KR840001585A (xx) |
| CS (1) | CS232735B2 (xx) |
| DD (1) | DD209633A5 (xx) |
| DK (1) | DK399282A (xx) |
| ES (2) | ES515548A0 (xx) |
| FI (1) | FI823088L (xx) |
| GB (1) | GB2105719A (xx) |
| GR (1) | GR76701B (xx) |
| HU (1) | HU187575B (xx) |
| IL (1) | IL66726A0 (xx) |
| NZ (1) | NZ201833A (xx) |
| PH (1) | PH19756A (xx) |
| PL (1) | PL238158A1 (xx) |
| PT (1) | PT75518B (xx) |
| RO (1) | RO84456B (xx) |
| SU (1) | SU1169542A3 (xx) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3374410D1 (en) * | 1982-06-28 | 1987-12-17 | Bristol Myers Co | Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives |
| US4480098A (en) * | 1982-11-12 | 1984-10-30 | Eli Lilly And Company | Preparation of alkali metal thieno(furo)pyridines |
| US4525473A (en) * | 1983-03-30 | 1985-06-25 | Bristol-Myers Company | Cephalosporins |
| EP0137442A3 (de) * | 1983-10-08 | 1986-01-15 | Hoechst Aktiengesellschaft | Cephalosporinderivate und Verfahren zu ihrer Herstellung |
| GB2148289B (en) * | 1983-10-17 | 1987-09-23 | Lilly Co Eli | 3-bicyclicpyridinium-methyl cephalosporins |
| EP0182633A3 (en) * | 1984-11-20 | 1987-09-02 | Ici Pharma | Cephalosporin derivatives |
| EP0187456A1 (en) * | 1984-11-29 | 1986-07-16 | Ici Pharma | Cephalosporin derivatives |
| ATE89826T1 (de) * | 1985-03-01 | 1993-06-15 | Takeda Chemical Industries Ltd | Antibakterielle verbindungen, ihre herstellung und verwendung. |
| US4703118A (en) * | 1985-04-08 | 1987-10-27 | Eli Lilly And Company | Synthesis of 3-iodomethyl cephalosporins |
| US4714760A (en) * | 1985-08-20 | 1987-12-22 | Bristol-Myers Company | Cephalosporin intermediates |
| GB8626245D0 (en) * | 1985-11-27 | 1986-12-03 | Ici Pharma | Cephalosporin compounds |
| US4868294A (en) * | 1986-07-11 | 1989-09-19 | Bristol-Myers Company | Process for preparing cephalosporin intermediates |
| US4918067A (en) * | 1986-07-24 | 1990-04-17 | Beecham Group P.L.C. | Heterocyclic substituted penicillin antibiotics |
| TW526202B (en) | 1998-11-27 | 2003-04-01 | Shionogi & Amp Co | Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity |
| NZ520696A (en) * | 2000-02-10 | 2004-03-26 | Upjohn Co | Piperazine amide substituted oxazolidinone thioamides useful for treating bacteria infections |
| US6642238B2 (en) | 2000-02-10 | 2003-11-04 | Pharmacia And Upjohn Company | Oxazolidinone thioamides with piperazine amide substituents |
| US7847093B2 (en) | 2003-04-16 | 2010-12-07 | Sandoz Ag | Processes for the preparations of cefepime |
| ATE473986T1 (de) | 2003-04-16 | 2010-07-15 | Sandoz Ag | Verfahren zur herstellung von cefepim |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
| DE2760484C2 (xx) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp | |
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| FR2440738A1 (fr) * | 1978-11-13 | 1980-06-06 | Parcor | Medicament a base de derives des thieno (2,3-c) et (3,2-c) pyridines |
| DE3118732A1 (de) * | 1981-05-12 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
| DE3207840A1 (de) * | 1982-03-04 | 1983-09-15 | Hoechst Ag, 6230 Frankfurt | "cephalosporinderivate und verfahren zu ihrer herstellung" |
-
1982
- 1982-09-06 IL IL66726A patent/IL66726A0/xx unknown
- 1982-09-06 GR GR69206A patent/GR76701B/el unknown
- 1982-09-06 PL PL23815882A patent/PL238158A1/xx unknown
- 1982-09-06 RO RO108573A patent/RO84456B/ro unknown
- 1982-09-06 SU SU823485553A patent/SU1169542A3/ru active
- 1982-09-07 EP EP82304674A patent/EP0074268A3/en not_active Withdrawn
- 1982-09-07 DK DK399282A patent/DK399282A/da not_active Application Discontinuation
- 1982-09-07 PH PH27833A patent/PH19756A/en unknown
- 1982-09-07 PT PT75518A patent/PT75518B/pt unknown
- 1982-09-07 FI FI823088A patent/FI823088L/fi not_active Application Discontinuation
- 1982-09-07 GB GB08225403A patent/GB2105719A/en not_active Withdrawn
- 1982-09-07 ES ES515548A patent/ES515548A0/es active Granted
- 1982-09-07 HU HU822856A patent/HU187575B/hu unknown
- 1982-09-07 DD DD82243071A patent/DD209633A5/de unknown
- 1982-09-07 KR KR1019820004043A patent/KR840001585A/ko unknown
- 1982-09-07 NZ NZ201833A patent/NZ201833A/xx unknown
- 1982-09-08 CS CS826505A patent/CS232735B2/cs unknown
-
1983
- 1983-12-02 ES ES527763A patent/ES527763A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CS650582A2 (en) | 1984-06-18 |
| EP0074268A2 (en) | 1983-03-16 |
| RO84456A (ro) | 1984-06-21 |
| FI823088L (fi) | 1983-03-09 |
| ES8505374A1 (es) | 1985-05-16 |
| IL66726A0 (en) | 1982-12-31 |
| FI823088A0 (fi) | 1982-09-07 |
| SU1169542A3 (ru) | 1985-07-23 |
| DK399282A (da) | 1983-03-09 |
| DD209633A5 (de) | 1984-05-16 |
| NZ201833A (en) | 1985-09-13 |
| ES527763A0 (es) | 1985-05-16 |
| ES8404361A1 (es) | 1984-04-16 |
| KR840001585A (ko) | 1984-05-07 |
| PT75518A (en) | 1982-10-01 |
| HU187575B (en) | 1986-01-28 |
| PH19756A (en) | 1986-06-26 |
| GB2105719A (en) | 1983-03-30 |
| EP0074268A3 (en) | 1984-05-23 |
| RO84456B (ro) | 1984-08-30 |
| PT75518B (en) | 1985-11-12 |
| PL238158A1 (en) | 1984-11-19 |
| ES515548A0 (es) | 1984-04-16 |
| GR76701B (xx) | 1984-08-29 |
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