RO84456A - Procedeu pentru prepararea unor derivati de cefalosporina tieno si furopiridiniu substituita - Google Patents

Procedeu pentru prepararea unor derivati de cefalosporina tieno si furopiridiniu substituita

Info

Publication number
RO84456A
RO84456A RO82108573A RO10857382A RO84456A RO 84456 A RO84456 A RO 84456A RO 82108573 A RO82108573 A RO 82108573A RO 10857382 A RO10857382 A RO 10857382A RO 84456 A RO84456 A RO 84456A
Authority
RO
Romania
Prior art keywords
furopiridinium
cyfalosporine
tieno
derivatives
substituted
Prior art date
Application number
RO82108573A
Other languages
English (en)
French (fr)
Other versions
RO84456B (ro
Inventor
William H Lunn
Robert Th Vasileff
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of RO84456A publication Critical patent/RO84456A/ro
Publication of RO84456B publication Critical patent/RO84456B/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/46Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
RO108573A 1981-09-08 1982-09-06 Procedeu pentru prepararea unor derivati de cefalosporina tieno si furopiridiniu substituita RO84456B (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30035781A 1981-09-08 1981-09-08
US34062882A 1982-01-19 1982-01-19

Publications (2)

Publication Number Publication Date
RO84456A true RO84456A (ro) 1984-06-21
RO84456B RO84456B (ro) 1984-08-30

Family

ID=26971737

Family Applications (1)

Application Number Title Priority Date Filing Date
RO108573A RO84456B (ro) 1981-09-08 1982-09-06 Procedeu pentru prepararea unor derivati de cefalosporina tieno si furopiridiniu substituita

Country Status (17)

Country Link
EP (1) EP0074268A3 (ro)
KR (1) KR840001585A (ro)
CS (1) CS232735B2 (ro)
DD (1) DD209633A5 (ro)
DK (1) DK399282A (ro)
ES (2) ES515548A0 (ro)
FI (1) FI823088L (ro)
GB (1) GB2105719A (ro)
GR (1) GR76701B (ro)
HU (1) HU187575B (ro)
IL (1) IL66726A0 (ro)
NZ (1) NZ201833A (ro)
PH (1) PH19756A (ro)
PL (1) PL238158A1 (ro)
PT (1) PT75518B (ro)
RO (1) RO84456B (ro)
SU (1) SU1169542A3 (ro)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0097961B1 (en) * 1982-06-28 1987-11-11 Bristol-Myers Company Cephalosporin derivatives, a process for the manufacture thereof and pharmaceutical compositions containing said derivatives
US4480098A (en) * 1982-11-12 1984-10-30 Eli Lilly And Company Preparation of alkali metal thieno(furo)pyridines
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
EP0137442A3 (de) * 1983-10-08 1986-01-15 Hoechst Aktiengesellschaft Cephalosporinderivate und Verfahren zu ihrer Herstellung
EP0138552A3 (en) * 1983-10-17 1986-03-19 Eli Lilly And Company Improvements on or relating to 3-bicyclicpyridinium-methyl cephalosporins
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
EP0187456A1 (en) * 1984-11-29 1986-07-16 Ici Pharma Cephalosporin derivatives
ATE89826T1 (de) * 1985-03-01 1993-06-15 Takeda Chemical Industries Ltd Antibakterielle verbindungen, ihre herstellung und verwendung.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
GB8626245D0 (en) * 1985-11-27 1986-12-03 Ici Pharma Cephalosporin compounds
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
US4918067A (en) * 1986-07-24 1990-04-17 Beecham Group P.L.C. Heterocyclic substituted penicillin antibiotics
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US6642238B2 (en) 2000-02-10 2003-11-04 Pharmacia And Upjohn Company Oxazolidinone thioamides with piperazine amide substituents
US20010047004A1 (en) * 2000-02-10 2001-11-29 Hester Jackson B. Oxazolidinone thioamides with piperazine amide substituents
ES2348299T3 (es) 2003-04-16 2010-12-02 Sandoz Ag Procedimientos para la preparación de cefepime.
US7847093B2 (en) 2003-04-16 2010-12-07 Sandoz Ag Processes for the preparations of cefepime

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
DE2760484C2 (ro) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2440738A1 (fr) * 1978-11-13 1980-06-06 Parcor Medicament a base de derives des thieno (2,3-c) et (3,2-c) pyridines
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3207840A1 (de) * 1982-03-04 1983-09-15 Hoechst Ag, 6230 Frankfurt "cephalosporinderivate und verfahren zu ihrer herstellung"

Also Published As

Publication number Publication date
ES8404361A1 (es) 1984-04-16
GR76701B (ro) 1984-08-29
CS232735B2 (en) 1985-02-14
ES8505374A1 (es) 1985-05-16
SU1169542A3 (ru) 1985-07-23
GB2105719A (en) 1983-03-30
PL238158A1 (en) 1984-11-19
FI823088A0 (fi) 1982-09-07
DD209633A5 (de) 1984-05-16
ES527763A0 (es) 1985-05-16
PT75518B (en) 1985-11-12
KR840001585A (ko) 1984-05-07
EP0074268A3 (en) 1984-05-23
PT75518A (en) 1982-10-01
RO84456B (ro) 1984-08-30
ES515548A0 (es) 1984-04-16
HU187575B (en) 1986-01-28
IL66726A0 (en) 1982-12-31
PH19756A (en) 1986-06-26
CS650582A2 (en) 1984-06-18
DK399282A (da) 1983-03-09
NZ201833A (en) 1985-09-13
EP0074268A2 (en) 1983-03-16
FI823088L (fi) 1983-03-09

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