CS226153B2 - Method of preparing new stable neutral water-soluble complexes of tetracyclin series antibiotics - Google Patents

Method of preparing new stable neutral water-soluble complexes of tetracyclin series antibiotics Download PDF

Info

Publication number
CS226153B2
CS226153B2 CS726077A CS607772A CS226153B2 CS 226153 B2 CS226153 B2 CS 226153B2 CS 726077 A CS726077 A CS 726077A CS 607772 A CS607772 A CS 607772A CS 226153 B2 CS226153 B2 CS 226153B2
Authority
CS
Czechoslovakia
Prior art keywords
complexes
tetracycline
solution
series
antibiotics
Prior art date
Application number
CS726077A
Other languages
Czech (cs)
English (en)
Inventor
Ilona Dr Kahan
Helga Dr Hammer
Ilona Dr Beladi
Original Assignee
Kahan Ilona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kahan Ilona filed Critical Kahan Ilona
Publication of CS226153B2 publication Critical patent/CS226153B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS726077A 1971-09-06 1972-09-05 Method of preparing new stable neutral water-soluble complexes of tetracyclin series antibiotics CS226153B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4153371A GB1401178A (en) 1971-09-06 1971-09-06 Complexes of tetracyclines

Publications (1)

Publication Number Publication Date
CS226153B2 true CS226153B2 (en) 1984-03-19

Family

ID=10420133

Family Applications (1)

Application Number Title Priority Date Filing Date
CS726077A CS226153B2 (en) 1971-09-06 1972-09-05 Method of preparing new stable neutral water-soluble complexes of tetracyclin series antibiotics

Country Status (10)

Country Link
US (1) US4418060A (pl)
JP (1) JPS587610B2 (pl)
BE (1) BE788479A (pl)
CS (1) CS226153B2 (pl)
DE (1) DE2243776C2 (pl)
FR (1) FR2154464B1 (pl)
GB (1) GB1401178A (pl)
HK (1) HK58877A (pl)
PL (1) PL83459B1 (pl)
YU (1) YU225972A (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE788479A (fr) 1971-09-06 1973-01-02 Medimpex Gyogyszerkulkereskede Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques
WO1999058131A1 (en) * 1998-05-08 1999-11-18 University Of Miami Use of tetracyclines for treating meibomian gland disease
EP1153010A1 (en) 1999-02-08 2001-11-14 Checkpoint Genetics, Inc. $i(N)-SUBSTITUTED AMINO ACIDS, ANTIOXIDANT PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND METHODS USING SAME
CN1893956A (zh) * 2003-07-25 2007-01-10 沃纳奇尔科特公司 多西环素金属络合物固体剂型
CA2767912C (en) 2004-05-21 2015-08-11 President And Fellows Of Harvard College Synthesis of tetracyclines and analogues thereof
NZ556582A (en) * 2005-01-21 2010-12-24 Warner Chilcott Co Llc A tetracycline metal complex in a solid dosage form
US8486921B2 (en) * 2006-04-07 2013-07-16 President And Fellows Of Harvard College Synthesis of tetracyclines and analogues thereof
EP2076133B1 (en) 2006-10-11 2012-12-12 President and Fellows of Harvard College Synthesis of enone intermediate
WO2010126607A2 (en) 2009-04-30 2010-11-04 President And Fellows Of Harvard College Synthesis of tetracyclines and intermediates thereto

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754346A (fr) * 1969-08-06 1971-01-18 Bru Jean Composition pharmaceutique a base de tetracycline presentee sous une forme effervescente
BE788479A (fr) 1971-09-06 1973-01-02 Medimpex Gyogyszerkulkereskede Complexes du tris(hydroxymethyl)aminomethane avec les tetracyclines formant des solutions neutres, stables, tres actives etnon toxiques

Also Published As

Publication number Publication date
DE2243776C2 (de) 1983-01-27
FR2154464B1 (pl) 1975-10-31
DE2243776A1 (de) 1973-03-22
JPS4861610A (pl) 1973-08-29
GB1401178A (en) 1975-07-16
PL83459B1 (pl) 1975-12-31
US4418060A (en) 1983-11-29
JPS587610B2 (ja) 1983-02-10
BE788479A (fr) 1973-01-02
HK58877A (en) 1977-12-02
FR2154464A1 (pl) 1973-05-11
YU225972A (en) 1982-02-28

Similar Documents

Publication Publication Date Title
US4126680A (en) Tetracycline antibiotic compositions
US3557280A (en) Stable solutions of oxytetracycline suitable for parenteral and peroral administration and process of preparation
BG60934B2 (bg) Терапевтични състави,съдържащи антрациклинови глюкозиди
CS226153B2 (en) Method of preparing new stable neutral water-soluble complexes of tetracyclin series antibiotics
ES2215183T3 (es) Disoluciones inyectables o de infusion de enrofloxacino.
US5750131A (en) Ifosfamide lyophilizate preparations
JPH1180022A (ja) バンコマイシンの凍結乾燥製剤
EP0012495B1 (en) Pharmaceutical composition comprising a water soluble salt of amoxycillin and polyvinylpyrrolidone, and a vial containing a unit dose of said composition
JPS605567B2 (ja) オキシテトラサイクリンの調合液
MX2007008082A (es) Formulaciones farmaceuticas de sales de galio.
EP0397147B1 (en) Stable solutions of rebeccamycin analog and preparation thereof
SE460457B (sv) Stabil, fast och vattenloeslig farmaceutisk komposition innehaallande 4'-(9-akridinylamino)-metansulfon-m-anisidid (m-amsa)
JPS5914447B2 (ja) ｐＨおよび色安定化非経口投与用水性抗性物質組成物
US20210169873A1 (en) Storage-stable ready-to-use injectable formulations of Trabectedin
US6060498A (en) Composition containing antitumor agent
JPH0343251B2 (pl)
US3461161A (en) Water-soluble tetracycline derivatives
JP7611707B2 (ja) ダプトマイシン含有製剤、及びダプトマイシン含有製剤の製造方法
EP2978426B1 (en) Stable tigecycline composition
FI82378B (fi) Foerfarande foer framstaellning av injiserbara oxitetracyklinloesningar.
CN1087624A (zh) 精氨酸衍生物
US4322424A (en) Crystalline glucoconate salt of m-AMSA and compositions containing same
JPWO1997030706A1 (ja) 抗腫瘍剤含有組成物
US6979676B2 (en) Pharmaceutical composition containing and indolopyrrolocarbazole derivative
WO2025208216A1 (en) Tranexamic acid formulations