CS212724B2 - Process for the production of 2-(chlor-4-cyclopropylphenylimono)-imidazolidine - Google Patents

Process for the production of 2-(chlor-4-cyclopropylphenylimono)-imidazolidine Download PDF

Info

Publication number
CS212724B2
CS212724B2 CS805760A CS576080A CS212724B2 CS 212724 B2 CS212724 B2 CS 212724B2 CS 805760 A CS805760 A CS 805760A CS 576080 A CS576080 A CS 576080A CS 212724 B2 CS212724 B2 CS 212724B2
Authority
CS
Czechoslovakia
Prior art keywords
imidazolidine
chloro
acid addition
formula
pct
Prior art date
Application number
CS805760A
Other languages
Czech (cs)
English (en)
Inventor
Helmut Staehle
Herbert Koeppe
Werner Kummer
Wolfgang Hoefke
Ludwig Pichler
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of CS212724B2 publication Critical patent/CS212724B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Seasonings (AREA)
CS805760A 1979-08-22 1980-08-22 Process for the production of 2-(chlor-4-cyclopropylphenylimono)-imidazolidine CS212724B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792933930 DE2933930A1 (de) 1979-08-22 1979-08-22 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.

Publications (1)

Publication Number Publication Date
CS212724B2 true CS212724B2 (en) 1982-03-26

Family

ID=6079013

Family Applications (1)

Application Number Title Priority Date Filing Date
CS805760A CS212724B2 (en) 1979-08-22 1980-08-22 Process for the production of 2-(chlor-4-cyclopropylphenylimono)-imidazolidine

Country Status (21)

Country Link
US (1) US4341788A (el)
EP (2) EP0024673B1 (el)
JP (1) JPS56501087A (el)
AT (1) ATE4204T1 (el)
BG (1) BG33281A3 (el)
CS (1) CS212724B2 (el)
DD (1) DD152783A5 (el)
DE (2) DE2933930A1 (el)
DK (1) DK157381A (el)
ES (1) ES8107191A1 (el)
FI (1) FI68815C (el)
GR (1) GR69874B (el)
HU (1) HU181790B (el)
IE (1) IE50114B1 (el)
NO (1) NO150118C (el)
PT (1) PT71725B (el)
RO (1) RO82161A (el)
SU (1) SU1021341A3 (el)
WO (1) WO1981000565A1 (el)
YU (1) YU211180A (el)
ZA (1) ZA805201B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7711390A (nl) * 1977-10-18 1979-04-20 Philips Nv Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.
HU192986B (en) * 1984-05-23 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Process for production of imidasodiline derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA462824A (en) * 1950-01-31 Frank Short Wallace Manufacture of heterocyclic amines
BE632578A (el) * 1963-05-22
NL7711390A (nl) * 1977-10-18 1979-04-20 Philips Nv Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen.
DE2831234A1 (de) * 1978-07-15 1980-01-31 Boehringer Sohn Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2) deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2854659A1 (de) * 1978-12-18 1980-07-10 Boehringer Sohn Ingelheim Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US4290971A (en) * 1979-01-19 1981-09-22 Dso "Pharmachim" Method of preparing 2-(phenylamino)-imidazolines-(2)

Also Published As

Publication number Publication date
HU181790B (en) 1983-11-28
ES494417A0 (es) 1981-08-16
WO1981000565A1 (en) 1981-03-05
IE801785L (en) 1981-02-22
RO82161B (ro) 1983-06-30
YU211180A (en) 1983-06-30
ZA805201B (en) 1982-07-28
EP0024673B1 (de) 1983-07-20
PT71725A (de) 1980-09-01
ATE4204T1 (de) 1983-08-15
JPS56501087A (el) 1981-08-06
FI68815B (fi) 1985-07-31
DD152783A5 (de) 1981-12-09
DK157381A (da) 1981-04-07
DE2933930A1 (de) 1981-03-12
BG33281A3 (en) 1983-01-14
US4341788A (en) 1982-07-27
GR69874B (el) 1982-07-20
PT71725B (pt) 1982-01-26
ES8107191A1 (es) 1981-08-16
EP0034623A1 (de) 1981-09-02
FI802651A (fi) 1981-02-23
DE3064276D1 (en) 1983-08-25
NO150118B (no) 1984-05-14
FI68815C (fi) 1985-11-11
IE50114B1 (en) 1986-02-19
RO82161A (ro) 1983-07-07
EP0034623B1 (de) 1983-07-20
SU1021341A3 (ru) 1983-05-30
NO150118C (no) 1984-08-22
NO811156L (no) 1981-04-03
EP0024673A1 (de) 1981-03-11

Similar Documents

Publication Publication Date Title
US3736331A (en) Isothioureas
US4250186A (en) Method of slowing heart rate
CA1088550A (en) 2-bromo-6-fluoro-n-2-imidazolidinylidene-benzamine
US4213995A (en) 2-Phenylimino-imidazolidines and salts thereof
CA1085861A (en) Substituted 2-phenylamino-imidazolines-(2), their acid addition salts, pharmaceuticals comprising same and processes for their production
US4285952A (en) Pyridyl, thiazolyl and isothiazolyl alkyl bisamidines
CS212724B2 (en) Process for the production of 2-(chlor-4-cyclopropylphenylimono)-imidazolidine
US3937717A (en) 2-phenylamino-imidazolines-(2)
US4277487A (en) Substituted 2-phenylamino-2-imidazolines as bradycardiacs
US4263300A (en) Substituted 2-phenylamino-1,3-tetrahydro-2-pyrimidines and salts thereof
EP0007991A1 (de) Neue substituierte 2-Phenylamino-imidazoline-(2), deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zur Herstellung derselben
KR860000669B1 (ko) 2-(2-클로로-4-사이클로프로필페닐이미노)-이미다졸리딘의 제조방법
US4036972A (en) 2-(N-thienylmethyl-phenylamino)-imidazolines-(2) and salts thereof
IE50485B1 (en) Novel substituted 2-phenylamino-imidazolines-(2),the acid addition salts thereof,pharmaceuticals containing same and processes for the preparation thereof
US4215133A (en) 2-[N-(2'-Chloro-4'-methyl-thienyl-3')-N-(cyclopropyl-methyl)-amino]-2-imidazoline and salts thereof
US4239764A (en) Substituted 2-phenylamino-2-imidazolines and salts thereof
KR820001715B1 (ko) 치환된 2-페닐이미노-이미다졸리딘의 제조방법
US4262006A (en) Substituted 2-phenylamino-imidazolines-(2) and pharmaceutical compositions containing them
CA1146949A (en) 2-(2-chloro-4-cyclopropyl-phenylimino)- imidazoidine, their acid addition salts, pharmaceuticals containing same and processes for production thereof
PL131883B1 (en) Process for preparing 2-/2-chloro-4-cyclopropylphenylimino/-imidazolidine
KR820001714B1 (ko) 치환된 2-페닐이미노-이미다졸리딘의 제조방법
NO792334L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive fenylamino-imidazol-derivater
NZ194833A (en) 2-(2-chloro-4-cyclopropylphenylimino)-imidazolidine and pharmaceutical compositions
CS199687B2 (cs) Způsob výroby nových substituovaných N-cykloalkylmethyl- -2-fenylamino-2-imidazolinů