RO82161B - Procedeu pentru prepararea 2-(2-clor-4-ciclopropilfenilimino)-imidazolidinei - Google Patents
Procedeu pentru prepararea 2-(2-clor-4-ciclopropilfenilimino)-imidazolidineiInfo
- Publication number
- RO82161B RO82161B RO104087A RO10408780A RO82161B RO 82161 B RO82161 B RO 82161B RO 104087 A RO104087 A RO 104087A RO 10408780 A RO10408780 A RO 10408780A RO 82161 B RO82161 B RO 82161B
- Authority
- RO
- Romania
- Prior art keywords
- chloro
- cyclopropylphenylimino
- imidazolidine
- preparation
- procedure
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- NJGRRCIKURPQPP-UHFFFAOYSA-N n-(2-chloro-4-cyclopropylphenyl)-4,5-dihydro-1h-imidazol-2-amine Chemical compound ClC1=CC(C2CC2)=CC=C1NC1=NCCN1 NJGRRCIKURPQPP-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- MGWOLLZLGIOWKU-UHFFFAOYSA-N [amino(methylsulfanyl)methylidene]-(2-chloro-4-cyclopropylphenyl)azanium;iodide Chemical compound [I-].C1=C(Cl)C([NH+]=C(N)SC)=CC=C1C1CC1 MGWOLLZLGIOWKU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- -1 aliphatic alcohols Chemical class 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Seasonings (AREA)
Abstract
Inventia se refera la un procedeu pentru prepararea 2-(2-clor-4-ciclopropilfenilimino)- imidazolidinei, caracterizat prin aceea ca se trateaza iodura de N-(2-clor-4-ciclopropilfenil)-S-metil-izotiuroniu cu etilendiamina în mediu de alcooli alifatici inferiori la temperatura de reflux, produsul obtinut putînd fi transformat într-o sare de aditie a acizilor, în mod cunoscut.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792933930 DE2933930A1 (de) | 1979-08-22 | 1979-08-22 | 2-(2-chlor-4-cyclopropyl-phenylimino)-imidazolidin, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO82161B true RO82161B (ro) | 1983-06-30 |
| RO82161A RO82161A (ro) | 1983-07-07 |
Family
ID=6079013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO80104087A RO82161A (ro) | 1979-08-22 | 1980-08-20 | Procedeu pentru prepararea 2-(2-clor-4-ciclopropilfenilimino)-imidazolidinei |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4341788A (ro) |
| EP (2) | EP0024673B1 (ro) |
| JP (1) | JPS56501087A (ro) |
| AT (1) | ATE4204T1 (ro) |
| BG (1) | BG33281A3 (ro) |
| CS (1) | CS212724B2 (ro) |
| DD (1) | DD152783A5 (ro) |
| DE (2) | DE2933930A1 (ro) |
| DK (1) | DK157381A (ro) |
| ES (1) | ES494417A0 (ro) |
| FI (1) | FI68815C (ro) |
| GR (1) | GR69874B (ro) |
| HU (1) | HU181790B (ro) |
| IE (1) | IE50114B1 (ro) |
| NO (1) | NO150118C (ro) |
| PT (1) | PT71725B (ro) |
| RO (1) | RO82161A (ro) |
| SU (1) | SU1021341A3 (ro) |
| WO (1) | WO1981000565A1 (ro) |
| YU (1) | YU211180A (ro) |
| ZA (1) | ZA805201B (ro) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7711390A (nl) * | 1977-10-18 | 1979-04-20 | Philips Nv | Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen. |
| HU192986B (en) * | 1984-05-23 | 1987-08-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of imidasodiline derivatives |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA462824A (en) * | 1950-01-31 | Frank Short Wallace | Manufacture of heterocyclic amines | |
| BE632578A (ro) * | 1963-05-22 | |||
| NL7711390A (nl) * | 1977-10-18 | 1979-04-20 | Philips Nv | Nieuwe 2-arylimino-hexahydopyrimidinen en - imi- dazolidinen, zouten en complexen daarvan, werk- wijze ter bereiding van de nieuwe verbindingen, alsmede fungicide preparaten op basis van de nieuwe verbindingen. |
| DE2831234A1 (de) * | 1978-07-15 | 1980-01-31 | Boehringer Sohn Ingelheim | Neue substituierte 2-phenylamino-imidazoline-(2) deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben |
| DE2854659A1 (de) * | 1978-12-18 | 1980-07-10 | Boehringer Sohn Ingelheim | Neue 3,4-disubstituierte 2-phenylimino-imidazolidine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
| US4290971A (en) * | 1979-01-19 | 1981-09-22 | Dso "Pharmachim" | Method of preparing 2-(phenylamino)-imidazolines-(2) |
-
1979
- 1979-08-22 DE DE19792933930 patent/DE2933930A1/de not_active Withdrawn
-
1980
- 1980-08-19 EP EP80104917A patent/EP0024673B1/de not_active Expired
- 1980-08-20 HU HU801056A patent/HU181790B/hu unknown
- 1980-08-20 DE DE8080901722T patent/DE3064276D1/de not_active Expired
- 1980-08-20 US US06/253,860 patent/US4341788A/en not_active Expired - Fee Related
- 1980-08-20 WO PCT/EP1980/000081 patent/WO1981000565A1/de not_active Ceased
- 1980-08-20 RO RO80104087A patent/RO82161A/ro unknown
- 1980-08-20 JP JP50203780A patent/JPS56501087A/ja active Pending
- 1980-08-20 AT AT80901722T patent/ATE4204T1/de not_active IP Right Cessation
- 1980-08-21 ES ES494417A patent/ES494417A0/es active Granted
- 1980-08-22 DD DD80223464A patent/DD152783A5/de unknown
- 1980-08-22 BG BG048913A patent/BG33281A3/xx unknown
- 1980-08-22 CS CS805760A patent/CS212724B2/cs unknown
- 1980-08-22 ZA ZA00805201A patent/ZA805201B/xx unknown
- 1980-08-22 FI FI802651A patent/FI68815C/fi not_active IP Right Cessation
- 1980-08-22 PT PT71725A patent/PT71725B/pt unknown
- 1980-08-22 GR GR62724A patent/GR69874B/el unknown
- 1980-08-22 IE IE1785/80A patent/IE50114B1/en unknown
- 1980-08-25 YU YU02111/80A patent/YU211180A/xx unknown
-
1981
- 1981-03-09 EP EP80901722A patent/EP0034623B1/de not_active Expired
- 1981-04-03 NO NO811156A patent/NO150118C/no unknown
- 1981-04-07 DK DK157381A patent/DK157381A/da not_active IP Right Cessation
- 1981-04-21 SU SU813272152A patent/SU1021341A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| PT71725B (pt) | 1982-01-26 |
| ATE4204T1 (de) | 1983-08-15 |
| JPS56501087A (ro) | 1981-08-06 |
| DK157381A (da) | 1981-04-07 |
| NO150118B (no) | 1984-05-14 |
| EP0034623A1 (de) | 1981-09-02 |
| DE2933930A1 (de) | 1981-03-12 |
| YU211180A (en) | 1983-06-30 |
| DD152783A5 (de) | 1981-12-09 |
| US4341788A (en) | 1982-07-27 |
| WO1981000565A1 (fr) | 1981-03-05 |
| GR69874B (ro) | 1982-07-20 |
| HU181790B (en) | 1983-11-28 |
| FI68815C (fi) | 1985-11-11 |
| IE50114B1 (en) | 1986-02-19 |
| BG33281A3 (bg) | 1983-01-14 |
| IE801785L (en) | 1981-02-22 |
| ES8107191A1 (es) | 1981-08-16 |
| SU1021341A3 (ru) | 1983-05-30 |
| EP0024673A1 (de) | 1981-03-11 |
| FI802651A7 (fi) | 1981-02-23 |
| RO82161A (ro) | 1983-07-07 |
| NO811156L (no) | 1981-04-03 |
| PT71725A (de) | 1980-09-01 |
| FI68815B (fi) | 1985-07-31 |
| CS212724B2 (en) | 1982-03-26 |
| NO150118C (no) | 1984-08-22 |
| EP0034623B1 (de) | 1983-07-20 |
| DE3064276D1 (en) | 1983-08-25 |
| ES494417A0 (es) | 1981-08-16 |
| EP0024673B1 (de) | 1983-07-20 |
| ZA805201B (en) | 1982-07-28 |
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