CS208159B2 - Method of making the steroid 16 alpha,17-b cyclohexenandtetrahydronphtalene-21-carboxyl acids of the pregnan series - Google Patents

Method of making the steroid 16 alpha,17-b cyclohexenandtetrahydronphtalene-21-carboxyl acids of the pregnan series Download PDF

Info

Publication number
CS208159B2
CS208159B2 CS794141A CS414179A CS208159B2 CS 208159 B2 CS208159 B2 CS 208159B2 CS 794141 A CS794141 A CS 794141A CS 414179 A CS414179 A CS 414179A CS 208159 B2 CS208159 B2 CS 208159B2
Authority
CS
Czechoslovakia
Prior art keywords
chloroform
hydrogen
acid
steroid
solution
Prior art date
Application number
CS794141A
Other languages
Czech (cs)
English (en)
Inventor
Kannadikovilakom Varma-Ravi
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/919,020 external-priority patent/US4164504A/en
Priority claimed from US05/919,006 external-priority patent/US4160772A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of CS208159B2 publication Critical patent/CS208159B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J53/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002Carbocyclic rings fused
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J13/00Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS794141A 1978-06-26 1979-06-15 Method of making the steroid 16 alpha,17-b cyclohexenandtetrahydronphtalene-21-carboxyl acids of the pregnan series CS208159B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/919,020 US4164504A (en) 1978-06-26 1978-06-26 Steroidal[16α,17-b]naphthaleno-21-carboxylic acid esters
US05/919,006 US4160772A (en) 1978-06-26 1978-06-26 Steroidal[16α,17-d]cyclohexene-21-carboxylic acid esters

Publications (1)

Publication Number Publication Date
CS208159B2 true CS208159B2 (en) 1981-08-31

Family

ID=27129763

Family Applications (2)

Application Number Title Priority Date Filing Date
CS794141A CS208159B2 (en) 1978-06-26 1979-06-15 Method of making the steroid 16 alpha,17-b cyclohexenandtetrahydronphtalene-21-carboxyl acids of the pregnan series
CS799420A CS208160B2 (en) 1978-06-26 1979-06-15 Method of making the steroid 16 alpha,17-b cyclohexen-and tetrahydronaphtalene-21-carboxyl acids of the pregnan series

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS799420A CS208160B2 (en) 1978-06-26 1979-06-15 Method of making the steroid 16 alpha,17-b cyclohexen-and tetrahydronaphtalene-21-carboxyl acids of the pregnan series

Country Status (24)

Country Link
AU (1) AU524173B2 (xx)
CA (1) CA1142916A (xx)
CH (1) CH642087A5 (xx)
CS (2) CS208159B2 (xx)
DD (1) DD144550A5 (xx)
DE (1) DE2925552A1 (xx)
DK (1) DK267079A (xx)
ES (2) ES481875A1 (xx)
FI (1) FI791934A (xx)
FR (1) FR2429796A1 (xx)
GB (2) GB2023608B (xx)
GR (1) GR72244B (xx)
HU (1) HU180089B (xx)
IE (1) IE49178B1 (xx)
IL (1) IL57622A (xx)
IT (1) IT1162746B (xx)
LU (1) LU81420A1 (xx)
NL (1) NL7904510A (xx)
NO (1) NO792118L (xx)
NZ (1) NZ190510A (xx)
PL (1) PL216614A1 (xx)
PT (1) PT69818A (xx)
SE (1) SE7905568L (xx)
SU (2) SU946404A3 (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391755A (en) * 1982-01-18 1983-07-05 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2924307A (en) * 1956-09-27 1960-02-09 Gen Motors Corp Brake adjusting device
US3944584A (en) * 1975-02-03 1976-03-16 E. R. Squibb & Sons, Inc. Steroidal (16α,17-d)cyclohexenes

Also Published As

Publication number Publication date
HU180089B (en) 1983-01-28
SE7905568L (sv) 1979-12-27
GB2106116B (en) 1983-08-03
GB2023608B (en) 1983-04-27
ES481866A1 (es) 1980-06-16
PT69818A (en) 1979-07-01
AU524173B2 (en) 1982-09-02
AU4748179A (en) 1980-01-03
FI791934A (fi) 1979-12-27
FR2429796A1 (fr) 1980-01-25
IE49178B1 (en) 1985-08-21
SU1055334A3 (ru) 1983-11-15
PL216614A1 (xx) 1980-03-24
DD144550A5 (de) 1980-10-22
CH642087A5 (de) 1984-03-30
CA1142916A (en) 1983-03-15
GR72244B (xx) 1983-10-04
ES481875A1 (es) 1980-07-01
DK267079A (da) 1979-12-27
IL57622A0 (en) 1979-10-31
FR2429796B1 (xx) 1983-01-07
IE791181L (en) 1979-12-26
NO792118L (no) 1979-12-28
NL7904510A (nl) 1979-12-28
IL57622A (en) 1983-02-23
GB2023608A (en) 1980-01-03
SU946404A3 (ru) 1982-07-23
IT1162746B (it) 1987-04-01
LU81420A1 (fr) 1979-09-12
DE2925552A1 (de) 1980-01-17
IT7923840A0 (it) 1979-06-25
NZ190510A (en) 1982-03-09
GB2106116A (en) 1983-04-07
CS208160B2 (en) 1981-08-31

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