ES481866A1 - Un procedimiento para preparar un esteroide. - Google Patents

Un procedimiento para preparar un esteroide.

Info

Publication number
ES481866A1
ES481866A1 ES481866A ES481866A ES481866A1 ES 481866 A1 ES481866 A1 ES 481866A1 ES 481866 A ES481866 A ES 481866A ES 481866 A ES481866 A ES 481866A ES 481866 A1 ES481866 A1 ES 481866A1
Authority
ES
Spain
Prior art keywords
hydrogen
steroid
translation
preparing
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481866A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/919,006 external-priority patent/US4160772A/en
Priority claimed from US05/919,020 external-priority patent/US4164504A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of ES481866A1 publication Critical patent/ES481866A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Un procedimiento para preparar un esteroide de la fórmula **(Fórmula 01)** y sus ésteres, o del derivado 1,2-deshidro del mismo, donde X es hidrógeno o halógeno; Y es hidrógeno, flúoro o metilo; R4 es cloro, flúoro o hidroxi y R5 es hidrógeno o R4 y R5 son, conjuntamente, O; R2 y R3 son iguales o diferentes, y son hidrógeno, alcohilo o arilo, o tomados conjuntamente con el doble enlace al cual están unidos, forman un anillo bencénico; R6 y R7 son iguales o diferentes y son hidrógeno, alcohilo, alcoxi, formilo o alcohil-C-O, fenilo o ciano, cuando R3 y R4 están separados, con la condición de que cuando R6 y R7 son diferentes, uno de los R6 y R7 es hidrógeno; R8 es hidrógeno o -CH-R9R10, donde R9 y R10 son iguales o diferentes, y son hidrógeno o alcohilo, caracterizado porque se oxida el correspondiente 21-hidroxi esteroide de la fórmula **(Fórmula 02)**
ES481866A 1978-06-26 1979-06-25 Un procedimiento para preparar un esteroide. Expired ES481866A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/919,006 US4160772A (en) 1978-06-26 1978-06-26 Steroidal[16α,17-d]cyclohexene-21-carboxylic acid esters
US05/919,020 US4164504A (en) 1978-06-26 1978-06-26 Steroidal[16α,17-b]naphthaleno-21-carboxylic acid esters

Publications (1)

Publication Number Publication Date
ES481866A1 true ES481866A1 (es) 1980-06-16

Family

ID=27129763

Family Applications (2)

Application Number Title Priority Date Filing Date
ES481875A Expired ES481875A1 (es) 1978-06-26 1979-06-25 Un procedimiento para preparar un esteroide
ES481866A Expired ES481866A1 (es) 1978-06-26 1979-06-25 Un procedimiento para preparar un esteroide.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES481875A Expired ES481875A1 (es) 1978-06-26 1979-06-25 Un procedimiento para preparar un esteroide

Country Status (24)

Country Link
AU (1) AU524173B2 (es)
CA (1) CA1142916A (es)
CH (1) CH642087A5 (es)
CS (2) CS208160B2 (es)
DD (1) DD144550A5 (es)
DE (1) DE2925552A1 (es)
DK (1) DK267079A (es)
ES (2) ES481875A1 (es)
FI (1) FI791934A (es)
FR (1) FR2429796A1 (es)
GB (2) GB2023608B (es)
GR (1) GR72244B (es)
HU (1) HU180089B (es)
IE (1) IE49178B1 (es)
IL (1) IL57622A (es)
IT (1) IT1162746B (es)
LU (1) LU81420A1 (es)
NL (1) NL7904510A (es)
NO (1) NO792118L (es)
NZ (1) NZ190510A (es)
PL (1) PL216614A1 (es)
PT (1) PT69818A (es)
SE (1) SE7905568L (es)
SU (2) SU946404A3 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391755A (en) * 1982-01-18 1983-07-05 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2924307A (en) * 1956-09-27 1960-02-09 Gen Motors Corp Brake adjusting device
US3944584A (en) * 1975-02-03 1976-03-16 E. R. Squibb & Sons, Inc. Steroidal (16α,17-d)cyclohexenes

Also Published As

Publication number Publication date
FI791934A (fi) 1979-12-27
IT7923840A0 (it) 1979-06-25
IL57622A0 (en) 1979-10-31
PL216614A1 (es) 1980-03-24
GB2106116A (en) 1983-04-07
GB2023608B (en) 1983-04-27
IL57622A (en) 1983-02-23
CS208160B2 (en) 1981-08-31
PT69818A (en) 1979-07-01
CS208159B2 (en) 1981-08-31
LU81420A1 (fr) 1979-09-12
CA1142916A (en) 1983-03-15
CH642087A5 (de) 1984-03-30
IE791181L (en) 1979-12-26
NO792118L (no) 1979-12-28
AU4748179A (en) 1980-01-03
DD144550A5 (de) 1980-10-22
SU1055334A3 (ru) 1983-11-15
HU180089B (en) 1983-01-28
AU524173B2 (en) 1982-09-02
FR2429796B1 (es) 1983-01-07
DK267079A (da) 1979-12-27
SE7905568L (sv) 1979-12-27
SU946404A3 (ru) 1982-07-23
NZ190510A (en) 1982-03-09
DE2925552A1 (de) 1980-01-17
IE49178B1 (en) 1985-08-21
GB2106116B (en) 1983-08-03
FR2429796A1 (fr) 1980-01-25
GR72244B (es) 1983-10-04
ES481875A1 (es) 1980-07-01
NL7904510A (nl) 1979-12-28
IT1162746B (it) 1987-04-01
GB2023608A (en) 1980-01-03

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