CS204037B2 - Method of preparing desoxynarasine antibiotic complex - Google Patents

Method of preparing desoxynarasine antibiotic complex Download PDF

Info

Publication number
CS204037B2
CS204037B2 CS786777A CS677778A CS204037B2 CS 204037 B2 CS204037 B2 CS 204037B2 CS 786777 A CS786777 A CS 786777A CS 677778 A CS677778 A CS 677778A CS 204037 B2 CS204037 B2 CS 204037B2
Authority
CS
Czechoslovakia
Prior art keywords
deoxynarasin
narasin
deoxy
epi
antibiotic
Prior art date
Application number
CS786777A
Other languages
Czech (cs)
English (en)
Inventor
Walter M Nakatsukasa
Gary G Marconi
Norbert Neuss
Robert L Hamill
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CS204037B2 publication Critical patent/CS204037B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces
    • C12R2001/485—Streptomyces aureofaciens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/886—Streptomyces
    • Y10S435/889—Streptomyces aureofaciens

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CS786777A 1977-10-20 1978-10-18 Method of preparing desoxynarasine antibiotic complex CS204037B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/844,087 US4141907A (en) 1977-10-20 1977-10-20 Deoxynarasin antibiotics

Publications (1)

Publication Number Publication Date
CS204037B2 true CS204037B2 (en) 1981-03-31

Family

ID=25291778

Family Applications (1)

Application Number Title Priority Date Filing Date
CS786777A CS204037B2 (en) 1977-10-20 1978-10-18 Method of preparing desoxynarasine antibiotic complex

Country Status (33)

Country Link
US (1) US4141907A (ja)
EP (1) EP0001709B1 (ja)
JP (1) JPS5470276A (ja)
AR (1) AR217869A1 (ja)
AT (1) AT362499B (ja)
AU (1) AU519966B2 (ja)
BE (1) BE871274A (ja)
CA (1) CA1119541A (ja)
CH (1) CH636903A5 (ja)
CS (1) CS204037B2 (ja)
DD (1) DD139520A5 (ja)
DE (1) DE2861882D1 (ja)
DK (1) DK465978A (ja)
ES (1) ES474327A1 (ja)
FI (1) FI58791C (ja)
FR (1) FR2406639A1 (ja)
GB (1) GB2006774B (ja)
GR (1) GR71734B (ja)
HU (1) HU179463B (ja)
IE (1) IE47665B1 (ja)
IL (1) IL55738A (ja)
IT (1) IT1101615B (ja)
MX (1) MX5603E (ja)
MY (1) MY8500595A (ja)
NO (1) NO783545L (ja)
NZ (1) NZ188670A (ja)
PH (1) PH14339A (ja)
PL (1) PL117570B1 (ja)
PT (1) PT68661A (ja)
RO (1) RO77417A (ja)
SU (1) SU818492A3 (ja)
YU (1) YU241578A (ja)
ZA (1) ZA785804B (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2024806B (en) * 1978-03-16 1982-05-06 Taisho Pharmaceutical Co Ltd Onomycin derivatives
IE49936B1 (en) * 1979-07-11 1986-01-08 Int Minerals & Chem Corp Zinc-containing antibiotic agents
US4309504A (en) * 1980-01-28 1982-01-05 Eli Lilly And Company Process for preparing narasin
US4394377A (en) * 1981-07-31 1983-07-19 Syntex (U.S.A.) Inc. Ruminant animal performance by co-administering choline and propionate enchancers
US4625041A (en) * 1984-02-17 1986-11-25 Pfizer Inc. Acidic polycyclic ether antibiotic
US4859599A (en) * 1984-10-11 1989-08-22 The Dow Chemical Company Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes
US4613503A (en) * 1984-10-11 1986-09-23 The Dow Chemical Company Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel strain of actinoplanes
US5041374A (en) * 1986-05-29 1991-08-20 International Minerals & Chemical Corp. Polyether antibiotic recovery and purification
US5049495A (en) * 1986-05-29 1991-09-17 International Minerals & Chemical Corp. Fermentation method for producing polyether antibiotics
US5047338A (en) * 1986-05-29 1991-09-10 International Minerals & Chemical Corp. Polyester Antibiotic preparation
WO2008033466A2 (en) * 2006-09-14 2008-03-20 Combinatorx (Singapore) Pre. Ltd. Compositions and methods for treatment of viral diseases
CN108743905A (zh) * 2018-08-24 2018-11-06 河南科技大学第附属医院 一种治疗感冒的中药配方及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753887A (en) 1969-06-04 1973-08-21 Hydronautics Alkali metal specific measuring electrode
US3947586A (en) 1974-05-20 1976-03-30 Hoffmann-La Roche Inc. Method of combatting swine dysentery
US4038384A (en) * 1974-06-10 1977-07-26 Eli Lilly And Company Antibiotic a-28086 and process for production thereof
US3985893A (en) 1974-10-29 1976-10-12 Eli Lilly And Company Method for treating cardiac insufficiency with antibiotic A-23187
US4035481A (en) 1975-04-21 1977-07-12 Eli Lilly And Company Antibiotic A-28086 and process for production thereof
US4009262A (en) 1975-04-21 1977-02-22 Eli Lilly And Company Antibiotic a-28086 recovery process

Also Published As

Publication number Publication date
IT7828926A0 (it) 1978-10-19
EP0001709A3 (en) 1979-05-16
JPS6244553B2 (ja) 1987-09-21
AU519966B2 (en) 1982-01-07
FI58791C (fi) 1981-04-10
IL55738A0 (en) 1978-12-17
CH636903A5 (fr) 1983-06-30
AT362499B (de) 1981-05-25
BE871274A (fr) 1979-04-17
FI783174A (fi) 1979-04-21
PT68661A (en) 1978-11-01
MY8500595A (en) 1985-12-31
FR2406639A1 (fr) 1979-05-18
SU818492A3 (ru) 1981-03-30
GB2006774A (en) 1979-05-10
IE47665B1 (en) 1984-05-16
IL55738A (en) 1981-10-30
EP0001709B1 (en) 1982-06-02
RO77417A (ro) 1981-11-04
PL117570B1 (en) 1981-08-31
CA1119541A (en) 1982-03-09
HU179463B (en) 1982-10-28
MX5603E (es) 1983-11-07
DK465978A (da) 1979-06-15
NO783545L (no) 1979-04-23
FR2406639B1 (ja) 1981-08-14
EP0001709A2 (en) 1979-05-02
YU241578A (en) 1982-10-31
ZA785804B (en) 1980-05-28
PL210410A1 (pl) 1979-10-22
ES474327A1 (es) 1979-11-01
US4141907A (en) 1979-02-27
AU4077678A (en) 1980-04-24
NZ188670A (en) 1981-05-29
IE782078L (en) 1979-04-20
PH14339A (en) 1981-05-29
DD139520A5 (de) 1980-01-09
DE2861882D1 (en) 1982-07-22
ATA750778A (de) 1980-10-15
IT1101615B (it) 1985-10-07
FI58791B (fi) 1980-12-31
GR71734B (ja) 1983-06-22
GB2006774B (en) 1982-09-02
JPS5470276A (en) 1979-06-05
AR217869A1 (es) 1980-04-30

Similar Documents

Publication Publication Date Title
KR840000750B1 (ko) 폴리에테르 화합물
US4582822A (en) Antibiotic A80190, pharmaceutical compositions containing same and method of use
CS204037B2 (en) Method of preparing desoxynarasine antibiotic complex
US4683201A (en) Antibiotic A80190-producing Actinomadura oligospora and process
JP2594778B2 (ja) 新規抗生物質
EP0334632A2 (en) Novel antibiotic
US4174404A (en) Deoxynarasin antibiotics
US4132778A (en) Antibiotic A-32887
US4133876A (en) Antibiotic A-32887 and process for production thereof
US4085224A (en) Method of increasing feed utilization
US4110435A (en) Antibiotic a-28086 factor d and process for production thereof
US4110436A (en) Antibiotic a-28086 factor d and process for production thereof
US4204039A (en) Process for producing deoxynarasin antibiotics
EP0156193B1 (en) Compounds and compositions for treating protozoal infections with a novel antibiotic
US3932619A (en) Metabolite A-27106 and processes for its preparation and use
IE58637B1 (en) Polyether antibiotic A80190
US4672036A (en) Pure cultures of Kibdelsporangium aridum Shearer gen. nov., sp. nov. ATCC 39323 and mutants thereof
US5242814A (en) Polyether antibiotic
KR820001203B1 (ko) 데옥시나라신 항생제의 제조방법
CA1041930A (en) Antibiotic a-28086 complex from streptomyces aureofaciens
US4797280A (en) Antibiotics produced by Kibdelosporangium aridum Shearer gen. nov., sp. nov. ATCC 39323
CS209848B2 (cs) Způsob přípravy polyetberických antibiotik A-28086
US5192748A (en) Antibiotics unphenelfamycin and phenelfamycins A-D
CA1320464C (en) Antibiotic a80190
HU196626B (en) Process for producing new antibiotic 6720 and pharmaceutic comprising same