CS203184B2 - Process for preparing new pyrroloquinoxalinones and pyrrolobenzodiazepinones - Google Patents
Process for preparing new pyrroloquinoxalinones and pyrrolobenzodiazepinones Download PDFInfo
- Publication number
- CS203184B2 CS203184B2 CS781094A CS109478A CS203184B2 CS 203184 B2 CS203184 B2 CS 203184B2 CS 781094 A CS781094 A CS 781094A CS 109478 A CS109478 A CS 109478A CS 203184 B2 CS203184 B2 CS 203184B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- phenyl
- acid
- dihydro
- calculated
- atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS792091A CS203185B2 (cs) | 1977-02-25 | 1979-03-29 | Způsob výroby 6-hydroxy-6-fenyl-lH-pyrrolo[1,2,3-de ]- -chinoxalin-2,5 (3H,6H) dionu |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/772,154 US4075206A (en) | 1977-02-25 | 1977-02-25 | Substituted pyrroloquinoxalinones and diones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS203184B2 true CS203184B2 (en) | 1981-02-27 |
Family
ID=25094096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS781094A CS203184B2 (en) | 1977-02-25 | 1978-02-21 | Process for preparing new pyrroloquinoxalinones and pyrrolobenzodiazepinones |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US4075206A (id) |
| JP (1) | JPS53111095A (id) |
| AR (1) | AR218056A1 (id) |
| AT (1) | AT361489B (id) |
| AU (1) | AU513391B2 (id) |
| BE (1) | BE864105A (id) |
| BG (1) | BG28565A3 (id) |
| CA (1) | CA1097631A (id) |
| CS (1) | CS203184B2 (id) |
| DD (1) | DD134871A5 (id) |
| DE (1) | DE2807145A1 (id) |
| DK (1) | DK74578A (id) |
| ES (1) | ES467189A1 (id) |
| FR (1) | FR2381767A1 (id) |
| GB (1) | GB1595745A (id) |
| GR (1) | GR68942B (id) |
| IL (1) | IL54086A0 (id) |
| IT (1) | IT1094215B (id) |
| NL (1) | NL7801927A (id) |
| NZ (1) | NZ186512A (id) |
| PH (1) | PH13147A (id) |
| PL (1) | PL204796A1 (id) |
| PT (1) | PT67678B (id) |
| SE (1) | SE7802024L (id) |
| YU (1) | YU39178A (id) |
| ZA (1) | ZA78991B (id) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4262123A (en) * | 1978-09-11 | 1981-04-14 | The Upjohn Company | Quinoxalinones |
| US4242342A (en) * | 1979-05-31 | 1980-12-30 | The Upjohn Company | Quinoxalinones useful for treating atopic eczema and urticaria |
| US4499270A (en) * | 1981-04-16 | 1985-02-12 | Riker Laboratories, Inc. | Substituted pyridoquinoxaline-6-carboxylic acids and derivatives thereof |
| IL93136A (en) * | 1989-02-23 | 1995-01-24 | Janssen Pharmaceutica Nv | History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them |
| NZ235137A (en) * | 1989-09-13 | 1992-02-25 | Janssen Pharmaceutica Nv | Tetrahydroimidazo(1,4)benzodiazepine derivatives, preparation and pharmaceutical compositions thereof |
| JPH05117276A (ja) * | 1991-10-23 | 1993-05-14 | Sumitomo Pharmaceut Co Ltd | 新規な３環性キノキサリンジオン誘導体 |
| TW260660B (id) * | 1993-04-22 | 1995-10-21 | Sumitomo Pharma | |
| CN114230528B (zh) * | 2021-11-25 | 2024-02-06 | 桂林理工大学 | 一种制备喹喔啉酮衍生物的方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3813392A (en) * | 1969-06-09 | 1974-05-28 | J Sellstedt | Pyrrolo(1,2,3-alpha epsilon)quinoxalin-2(3h)-ones and related compounds |
| US3892746A (en) * | 1969-06-09 | 1975-07-01 | American Home Prod | Pyrrolo{8 1,2,3-de{9 quinoxalin-2(3H)-ones and related compounds |
| US3642821A (en) * | 1969-11-03 | 1972-02-15 | Upjohn Co | Tetrahydropyrrolobenzodiazepines |
| US3579503A (en) * | 1969-11-03 | 1971-05-18 | Upjohn Co | Pyrrolo(3,2,1-jk)(1,4)benzodiazepinones |
-
1977
- 1977-02-25 US US05/772,154 patent/US4075206A/en not_active Expired - Lifetime
- 1977-09-26 US US05/836,830 patent/US4087527A/en not_active Expired - Lifetime
-
1978
- 1978-02-17 GB GB6298/78A patent/GB1595745A/en not_active Expired
- 1978-02-20 JP JP1902178A patent/JPS53111095A/ja active Pending
- 1978-02-20 PT PT67678A patent/PT67678B/pt unknown
- 1978-02-20 AU AU33433/78A patent/AU513391B2/en not_active Expired
- 1978-02-20 PH PH20799A patent/PH13147A/en unknown
- 1978-02-20 AR AR271156A patent/AR218056A1/es active
- 1978-02-20 CA CA297,309A patent/CA1097631A/en not_active Expired
- 1978-02-20 DK DK74578A patent/DK74578A/da unknown
- 1978-02-20 IL IL54086A patent/IL54086A0/xx unknown
- 1978-02-20 DE DE19782807145 patent/DE2807145A1/de not_active Withdrawn
- 1978-02-20 GR GR55496A patent/GR68942B/el unknown
- 1978-02-20 NZ NZ186512A patent/NZ186512A/xx unknown
- 1978-02-20 IT IT20417/78A patent/IT1094215B/it active
- 1978-02-20 FR FR7804728A patent/FR2381767A1/fr active Pending
- 1978-02-20 ZA ZA00780991A patent/ZA78991B/xx unknown
- 1978-02-20 BE BE1008716A patent/BE864105A/xx unknown
- 1978-02-21 DD DD78203784A patent/DD134871A5/xx unknown
- 1978-02-21 YU YU00391/78A patent/YU39178A/xx unknown
- 1978-02-21 SE SE7802024A patent/SE7802024L/xx unknown
- 1978-02-21 CS CS781094A patent/CS203184B2/cs unknown
- 1978-02-21 ES ES467189A patent/ES467189A1/es not_active Expired
- 1978-02-21 BG BG7838764A patent/BG28565A3/xx unknown
- 1978-02-21 NL NL7801927A patent/NL7801927A/xx not_active Application Discontinuation
- 1978-02-21 PL PL20479678A patent/PL204796A1/xx unknown
- 1978-02-23 AT AT131578A patent/AT361489B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IT7820417A0 (it) | 1978-02-20 |
| US4087527A (en) | 1978-05-02 |
| DE2807145A1 (de) | 1978-08-31 |
| ES467189A1 (es) | 1979-08-16 |
| FR2381767A1 (fr) | 1978-09-22 |
| US4075206A (en) | 1978-02-21 |
| SE7802024L (sv) | 1978-08-26 |
| IT1094215B (it) | 1985-07-26 |
| CA1097631A (en) | 1981-03-17 |
| AU513391B2 (en) | 1980-11-27 |
| BE864105A (fr) | 1978-08-21 |
| PL204796A1 (pl) | 1979-04-09 |
| DK74578A (da) | 1978-08-26 |
| GB1595745A (en) | 1981-08-19 |
| AT361489B (de) | 1981-03-10 |
| IL54086A0 (en) | 1978-04-30 |
| NZ186512A (en) | 1981-03-16 |
| GR68942B (id) | 1982-03-29 |
| PT67678B (en) | 1979-07-20 |
| ATA131578A (de) | 1980-08-15 |
| AR218056A1 (es) | 1980-05-15 |
| PH13147A (en) | 1979-12-18 |
| DD134871A5 (de) | 1979-03-28 |
| JPS53111095A (en) | 1978-09-28 |
| AU3343378A (en) | 1979-08-30 |
| PT67678A (en) | 1978-03-01 |
| NL7801927A (nl) | 1978-08-29 |
| ZA78991B (en) | 1979-10-31 |
| YU39178A (en) | 1983-01-21 |
| BG28565A3 (id) | 1980-05-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4062848A (en) | Tetracyclic compounds | |
| KR900007780B1 (ko) | 축합된 피롤리논 유도체의 제조방법 | |
| JPH0327380A (ja) | １ｈ―イミダゾ〔４，５―ｃ〕キノリン―４―アミン類 | |
| FI86425C (fi) | Foerfarande foer framstaellning av terapeutiskt aktiva 6-benzoxazinyl- och 6-benzotiazinyl-2,3,4,5- tetrahydropyridazin-3-oner. | |
| PT760819E (pt) | Derivado dicarbonilicos triciclicos | |
| US4663326A (en) | Pyrazolo[4,3-d]pyrimidine-5,7-(4H,6H)dione or -5-thione-7-one analogs | |
| US5753657A (en) | Imidazo 1,2-A! pyrazine-4-one, preparation thereof and drugs containing same | |
| JPS63107990A (ja) | キノリンカルボン酸誘導体 | |
| US5677306A (en) | Derivatives of 5H, 10H-imidazo 1, 2-a!indeno 1,2-e!pyrazin-4-one, preparation thereof and medicaments containing them | |
| CS203184B2 (en) | Process for preparing new pyrroloquinoxalinones and pyrrolobenzodiazepinones | |
| IE44379B1 (en) | Thiazolo (3,4-b)isoquinoline derivatives | |
| US4581172A (en) | Substituted pyrimido[6,1-a]isoquinolin-4-ones,pyrimido[6,1-a]benzozepin-4-ones and pyrimido[6,1-a]benzodiazepin-4-ones useful for prevention of thromboses and treating hypertension | |
| PL184860B1 (pl) | Chinoksaliny o własnościach leczniczychĆ zwłaszcza antywirusowychĆ sposób ich wytwarzania i środki lecznicze zawierające chinoksaliny jako substancje czynne | |
| US4678791A (en) | 6-phenyl-1,2-3,4,4a,5-6,10b-octahydrobenz(h)isoquinolines useful for treating depression | |
| US3636041A (en) | 4 5-dihydro-7h-thieno(2 3-c)thiopyrans | |
| US4143142A (en) | Novel pyrido-imidazo-indoles, compositions and method therewith | |
| EA005071B1 (ru) | ЗАМЕЩЕННЫЕ ПИРАЗОЛО[4,3-e]ДИАЗЕПИНЫ, ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ИХ, И ПРИМЕНЕНИЕ В КАЧЕСТВЕ ЛЕКАРСТВЕННЫХ ПРОДУКТОВ | |
| US3555018A (en) | Thiazinopyridoindolone derivatives | |
| US4255573A (en) | Imidazoindole derivatives and pharmaceutical compositions comprising imidazoindole derivatives | |
| US3891643A (en) | Pyrrolo{8 1,2,3-de{9 quinoxalin-2-(3H)-ones and related compounds | |
| US4372956A (en) | 5, 10-Dihydroimidazo[2,1-b]quinazolines and pharmaceutical compositions containing them | |
| JPH06211841A (ja) | β−カルボリン由来化合物、逆アゴニスト及びアンタゴニスト作用を有するベンゾジアゼピンレセプターリガンド及びそれを含有する薬剤 | |
| JP3295149B2 (ja) | ピロロ［３，２−ｅ］ピラゾロ［１，５−ａ］ピリミジン誘導体 | |
| US4133884A (en) | Substituted pyrroloquinoxalinones and diones used in treating inflammation in warm blooded mammals | |
| US3842080A (en) | 7-phenylpyrimido(1,2-a)(1,4)benzodiazepin-1(5h)-ones |