CS196267B2 - Method of producing water-soluble compounds having low-molecular weight,containing diamino pimelic acid - Google Patents
Method of producing water-soluble compounds having low-molecular weight,containing diamino pimelic acid Download PDFInfo
- Publication number
- CS196267B2 CS196267B2 CS753097A CS309775A CS196267B2 CS 196267 B2 CS196267 B2 CS 196267B2 CS 753097 A CS753097 A CS 753097A CS 309775 A CS309775 A CS 309775A CS 196267 B2 CS196267 B2 CS 196267B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- water
- soluble
- carried out
- process according
- molecular weight
- Prior art date
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- GMKMEZVLHJARHF-UHFFFAOYSA-N (2R,6R)-form-2.6-Diaminoheptanedioic acid Natural products OC(=O)C(N)CCCC(N)C(O)=O GMKMEZVLHJARHF-UHFFFAOYSA-N 0.000 title claims abstract description 15
- 238000000034 method Methods 0.000 title claims description 33
- GMKMEZVLHJARHF-WHFBIAKZSA-N LL-2,6-diaminopimelic acid Chemical compound OC(=O)[C@@H](N)CCC[C@H](N)C(O)=O GMKMEZVLHJARHF-WHFBIAKZSA-N 0.000 title description 2
- 150000001875 compounds Chemical class 0.000 title description 2
- GMKMEZVLHJARHF-SYDPRGILSA-N meso-2,6-diaminopimelic acid Chemical compound [O-]C(=O)[C@@H]([NH3+])CCC[C@@H]([NH3+])C([O-])=O GMKMEZVLHJARHF-SYDPRGILSA-N 0.000 claims abstract description 14
- 238000000605 extraction Methods 0.000 claims abstract description 12
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- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 5
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- JVIPLYCGEZUBIO-UHFFFAOYSA-N 2-(4-fluorophenyl)-1,3-dioxoisoindole-5-carboxylic acid Chemical compound O=C1C2=CC(C(=O)O)=CC=C2C(=O)N1C1=CC=C(F)C=C1 JVIPLYCGEZUBIO-UHFFFAOYSA-N 0.000 claims description 3
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 235000004279 alanine Nutrition 0.000 description 3
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- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 description 2
- FTOAOBMCPZCFFF-UHFFFAOYSA-N 5,5-diethylbarbituric acid Chemical compound CCC1(CC)C(=O)NC(=O)NC1=O FTOAOBMCPZCFFF-UHFFFAOYSA-N 0.000 description 2
- 229920000189 Arabinogalactan Polymers 0.000 description 2
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- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 description 2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55516—Proteins; Peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55588—Adjuvants of undefined constitution
- A61K2039/55594—Adjuvants of undefined constitution from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7415570A FR2269961B1 (en, 2012) | 1974-05-06 | 1974-05-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS196267B2 true CS196267B2 (en) | 1980-03-31 |
Family
ID=9138474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS753097A CS196267B2 (en) | 1974-05-06 | 1975-05-05 | Method of producing water-soluble compounds having low-molecular weight,containing diamino pimelic acid |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4013788A (en, 2012) |
| JP (1) | JPS50155685A (en, 2012) |
| BE (1) | BE828635A (en, 2012) |
| CA (1) | CA1037028A (en, 2012) |
| CH (1) | CH604725A5 (en, 2012) |
| CS (1) | CS196267B2 (en, 2012) |
| DE (1) | DE2519938A1 (en, 2012) |
| DK (1) | DK194975A (en, 2012) |
| FR (1) | FR2269961B1 (en, 2012) |
| GB (1) | GB1502320A (en, 2012) |
| IL (1) | IL47205A (en, 2012) |
| NL (1) | NL7505246A (en, 2012) |
| SE (1) | SE7505032L (en, 2012) |
| SU (1) | SU727112A3 (en, 2012) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2320107A1 (fr) * | 1975-08-05 | 1977-03-04 | Anvar | Nouveaux adjuvants immunologiques, procede pour leur obtention et compositions les contenant |
| FR2321896A1 (fr) * | 1975-08-29 | 1977-03-25 | Anvar | Agents adjuvants immunologiques actifs en solution aqueuse |
| US4148877A (en) * | 1975-12-29 | 1979-04-10 | Choay S. A. | Fraction capable of inducing in vivo a resistance to bacterial infections, process for obtaining said fraction from bacteria and drugs containing said fraction |
| FR2374042A1 (fr) * | 1976-06-04 | 1978-07-13 | Merieux Inst | Nouveau medicament immunostimulant et son procede de preparation |
| FR2378855A1 (fr) * | 1977-01-27 | 1978-08-25 | Cassenne Lab Sa | Nouvelles glycoproteines isolees d'hafnia, procede de preparation et application a titre de medicaments |
| GB1598457A (en) * | 1977-03-22 | 1981-09-23 | Glaxo Lab Ltd | Process for the preparation of a fraction containing peptidoglycan material from streptomyces griseus |
| JPS58874B2 (ja) * | 1979-08-30 | 1983-01-08 | 株式会社 目黒研究所 | 糖蛋白ｗｅｎａｃ及びその製造法 |
| DE3011461C2 (de) * | 1980-03-25 | 1986-10-30 | Dr. Madaus & Co, 5000 Köln | Verwendung von Propionibakterien |
| FR2480604A1 (fr) * | 1980-04-22 | 1981-10-23 | Pasteur Institut | Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon et leur procede de preparation |
| US4479935A (en) * | 1980-04-22 | 1984-10-30 | Institut Pasteur | Fractions extracted from aerobic bacteria, endowed with antitumoral, antibacterial and interferon inducing properties, and process for their preparation |
| FR2490496A1 (fr) * | 1980-09-19 | 1982-03-26 | Roussel Uclaf | Nouvelles glycoproteines immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
| FR2490495A1 (fr) * | 1980-09-19 | 1982-03-26 | Roussel Uclaf | Nouvelles glycoproteines hydrosolubles immunostimulantes extraites de klebsiella pneumoniae, leur procede d'obtention, leur application a titre de medicaments et les compositions les renfermant |
| JPS57163835U (en, 2012) * | 1981-04-07 | 1982-10-15 | ||
| JPH0742310B2 (ja) * | 1984-01-23 | 1995-05-10 | 味の素株式会社 | Ｌ−アスパルチル−ｌ−フエニルアラニン又はその低級アルキルエステルの晶析法 |
| IT1237903B (it) * | 1989-12-14 | 1993-06-18 | Medidom Lab | Derivati semisintetici ad attivita' immunomodulante atti alla somminitrazione parenterale ed orale |
| WO1994016727A1 (en) * | 1993-01-29 | 1994-08-04 | Vetrepharm, Inc. | Immunotherapeutic composition |
| US5976580A (en) | 1995-06-07 | 1999-11-02 | Novus International, Inc. | Nutrient formulation and process for enhancing the health, livability, cumulative weight gain or feed efficiency in poultry and other animals |
| JP4759182B2 (ja) * | 2001-08-03 | 2011-08-31 | 花王株式会社 | 水溶性ショウキョウエキス |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2189021A1 (en) | 1972-06-20 | 1974-01-25 | Anvar | Non-arthrogenic immunological adjuvants - obtained by extraction of lipid-free mycobacterial residues |
-
1974
- 1974-05-06 FR FR7415570A patent/FR2269961B1/fr not_active Expired
-
1975
- 1975-04-29 SE SE7505032A patent/SE7505032L/xx unknown
- 1975-04-30 IL IL47205A patent/IL47205A/xx unknown
- 1975-04-30 BE BE155997A patent/BE828635A/xx unknown
- 1975-04-30 US US05/573,200 patent/US4013788A/en not_active Expired - Lifetime
- 1975-05-02 JP JP50052653A patent/JPS50155685A/ja active Pending
- 1975-05-02 NL NL7505246A patent/NL7505246A/xx not_active Application Discontinuation
- 1975-05-05 DK DK194975A patent/DK194975A/da unknown
- 1975-05-05 SU SU752131288A patent/SU727112A3/ru active
- 1975-05-05 CH CH577475A patent/CH604725A5/xx not_active IP Right Cessation
- 1975-05-05 DE DE19752519938 patent/DE2519938A1/de active Pending
- 1975-05-05 CA CA226,296A patent/CA1037028A/en not_active Expired
- 1975-05-05 GB GB18754/75A patent/GB1502320A/en not_active Expired
- 1975-05-05 CS CS753097A patent/CS196267B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL47205A (en) | 1978-06-15 |
| GB1502320A (en) | 1978-03-01 |
| SU727112A3 (ru) | 1980-04-05 |
| FR2269961A1 (en, 2012) | 1975-12-05 |
| US4013788A (en) | 1977-03-22 |
| CH604725A5 (en, 2012) | 1978-09-15 |
| DE2519938A1 (de) | 1975-11-27 |
| BE828635A (fr) | 1975-10-30 |
| SE7505032L (sv) | 1975-11-07 |
| CA1037028A (en) | 1978-08-22 |
| JPS50155685A (en, 2012) | 1975-12-16 |
| NL7505246A (nl) | 1975-11-10 |
| IL47205A0 (en) | 1975-06-25 |
| DK194975A (da) | 1975-11-07 |
| FR2269961B1 (en, 2012) | 1978-03-24 |
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