CS191332B2 - Method of producing crystalline alpha-form of 2-/4-/2-furoyl/piperazine-1-yl/-4-amino-6,7-dimethoxy quinazoline hydrochloride - Google Patents
Method of producing crystalline alpha-form of 2-/4-/2-furoyl/piperazine-1-yl/-4-amino-6,7-dimethoxy quinazoline hydrochlorideInfo
- Publication number
- CS191332B2 CS191332B2 CS771358A CS135877A CS191332B2 CS 191332 B2 CS191332 B2 CS 191332B2 CS 771358 A CS771358 A CS 771358A CS 135877 A CS135877 A CS 135877A CS 191332 B2 CS191332 B2 CS 191332B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- furoyl
- piperazine
- amino
- producing crystalline
- quinazoline hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/662,937 US4092315A (en) | 1976-03-01 | 1976-03-01 | Novel crystalline forms of prazosin hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS191332B2 true CS191332B2 (en) | 1979-06-29 |
Family
ID=24659839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS771358A CS191332B2 (en) | 1976-03-01 | 1977-03-01 | Method of producing crystalline alpha-form of 2-/4-/2-furoyl/piperazine-1-yl/-4-amino-6,7-dimethoxy quinazoline hydrochloride |
Country Status (32)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
| MX5483E (es) * | 1977-08-04 | 1983-08-23 | Abbott Lab | Procedimiento para la preparacion del dihidrato clorhidrato de 1-(4-amino-6,7-dimetoxi-2-quinazolinil)-4-(2-tetrahidrofuroil)piperazina |
| US4197301A (en) * | 1978-10-16 | 1980-04-08 | Allergan Pharmaceuticals, Inc. | Topical ophthalmic use of Prazosin |
| FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
| US4440769A (en) * | 1983-02-11 | 1984-04-03 | Abbott Laboratories | 2-(4-Phenylalkanoylpiperazin-1-yl) quinazoline compounds, pharmaceutical compositions and method of producing α1 antagonistic activity |
| FI79107C (fi) * | 1984-06-25 | 1989-11-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid. |
| US5322943A (en) * | 1985-09-12 | 1994-06-21 | The Upjohn Company | Piperazine compounds which are substituted |
| US4601897A (en) * | 1985-11-06 | 1986-07-22 | Pfizer Inc. | Prazosin-pirbuterol combination for bronchodilation |
| DE3683760D1 (de) * | 1986-03-21 | 1992-03-12 | Heumann Pharma Gmbh & Co | Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung. |
| US5110927A (en) * | 1987-12-31 | 1992-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Prazosin analog with increased selectivity and duration of action |
| JP2652272B2 (ja) * | 1990-12-31 | 1997-09-10 | 住化ファインケム株式会社 | １−（４−アミノ−６，７−ジメトキシ−２−キナゾリニル）−４−（２−テトラヒドロフロイル）ピペラジン塩酸塩の新規な結晶体および該結晶体の製造方法 |
| GB9417310D0 (en) * | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
| US5952003A (en) * | 1996-08-01 | 1999-09-14 | Novartis Corporation | Terazosin capsules |
| EP0849265A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von Doxazosin-Mesylat (Form II) |
| EP0849264A1 (de) * | 1996-12-20 | 1998-06-24 | HEUMANN PHARMA GmbH | Neue polymorphe Form von doxazosinmesylat (Form I) |
| DK0849266T3 (da) * | 1996-12-20 | 2007-06-04 | Heumann Pcs Gmbh | Hidtil ukendt polymorf form af doxazosin-mesylat (form III) |
| CA2993152C (en) | 2014-07-21 | 2022-12-13 | Keir Manufacturing, Inc. | Aerodynamic flyer bow |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3635979A (en) * | 1969-09-29 | 1972-01-18 | Pfizer | Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines |
-
1976
- 1976-03-01 US US05/662,937 patent/US4092315A/en not_active Expired - Lifetime
-
1977
- 1977-02-11 GB GB5756/77A patent/GB1538713A/en not_active Expired
- 1977-02-14 SE SE7701624A patent/SE423234B/xx not_active IP Right Cessation
- 1977-02-16 ZA ZA770918A patent/ZA77918B/xx unknown
- 1977-02-17 IL IL51481A patent/IL51481A/xx unknown
- 1977-02-18 CA CA272,080A patent/CA1068269A/en not_active Expired
- 1977-02-18 AU AU22443/77A patent/AU506937B2/en not_active Expired
- 1977-02-23 YU YU499/77A patent/YU41294B/xx unknown
- 1977-02-24 PT PT66227A patent/PT66227B/pt unknown
- 1977-02-24 IE IE399/77A patent/IE44522B1/en not_active IP Right Cessation
- 1977-02-25 DE DE2708192A patent/DE2708192C3/de not_active Expired
- 1977-02-28 FI FI770634A patent/FI62082C/fi not_active IP Right Cessation
- 1977-02-28 BE BE1007976A patent/BE851878A/xx not_active IP Right Cessation
- 1977-02-28 JP JP52021433A patent/JPS604188B2/ja not_active Expired
- 1977-02-28 NL NLAANVRAGE7702123,A patent/NL169591C/xx not_active IP Right Cessation
- 1977-02-28 DK DK86877A patent/DK145858C/da not_active IP Right Cessation
- 1977-02-28 HU HU76UO128A patent/HU173641B/hu unknown
- 1977-02-28 NO NO770674A patent/NO146499C/no unknown
- 1977-02-28 ES ES545368A patent/ES8707447A1/es not_active Expired
- 1977-02-28 SU SU772457100A patent/SU644387A3/ru active
- 1977-02-28 FR FR7705819A patent/FR2372828A1/fr active Granted
- 1977-02-28 NZ NZ183450A patent/NZ183450A/xx unknown
- 1977-03-01 PL PL1977196354A patent/PL105559B1/pl not_active IP Right Cessation
- 1977-03-01 DD DD7700197618A patent/DD129652A5/xx unknown
- 1977-03-01 AR AR266724A patent/AR210937A1/es active
- 1977-03-01 CS CS771358A patent/CS191332B2/cs unknown
- 1977-03-01 CH CH255577A patent/CH618436A5/fr not_active IP Right Cessation
- 1977-03-01 RO RO7789566A patent/RO73095A/ro unknown
- 1977-03-01 LU LU76868A patent/LU76868A1/xx unknown
- 1977-03-01 BG BG035558A patent/BG29724A3/xx unknown
-
1981
- 1981-07-02 HK HK308/81A patent/HK30881A/xx unknown
- 1981-12-30 MY MY271/81A patent/MY8100271A/xx unknown
Also Published As
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