CS191322B2 - Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropane - Google Patents
Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropaneInfo
- Publication number
- CS191322B2 CS191322B2 CS766837A CS683776A CS191322B2 CS 191322 B2 CS191322 B2 CS 191322B2 CS 766837 A CS766837 A CS 766837A CS 683776 A CS683776 A CS 683776A CS 191322 B2 CS191322 B2 CS 191322B2
- Authority
- CS
- Czechoslovakia
- Prior art keywords
- phenolethers
- hydroxypropane
- amino
- preparing new
- new disubstituted
- Prior art date
Links
- HXKKHQJGJAFBHI-UHFFFAOYSA-N 1-aminopropan-2-ol Chemical compound CC(O)CN HXKKHQJGJAFBHI-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000008379 phenol ethers Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
- C07C217/36—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by carbon atoms having at least two bonds to oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752547524 DE2547524A1 (de) | 1975-10-23 | 1975-10-23 | Disubstituierte phenolaether des 3-amino-2-hydroxypropans, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CS191322B2 true CS191322B2 (en) | 1979-06-29 |
Family
ID=5959934
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS777809A CS191344B2 (en) | 1975-10-23 | 1976-10-22 | Method of producing novel disubstituted phenolethers of 3-amino-2-hydroxypropane |
| CS766837A CS191322B2 (en) | 1975-10-23 | 1976-10-22 | Process for preparing new disubstituted phenolethers of 3-amino-2-hydroxypropane |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CS777809A CS191344B2 (en) | 1975-10-23 | 1976-10-22 | Method of producing novel disubstituted phenolethers of 3-amino-2-hydroxypropane |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US4110472A (xx) |
| JP (1) | JPS5935387B2 (xx) |
| AT (2) | AT344682B (xx) |
| AU (1) | AU502167B2 (xx) |
| BE (1) | BE847541A (xx) |
| BG (2) | BG31796A3 (xx) |
| CA (1) | CA1085417A (xx) |
| CH (2) | CH623562A5 (xx) |
| CS (2) | CS191344B2 (xx) |
| DD (1) | DD128555A5 (xx) |
| DE (1) | DE2547524A1 (xx) |
| DK (1) | DK480376A (xx) |
| ES (1) | ES452616A1 (xx) |
| FI (1) | FI67075C (xx) |
| FR (1) | FR2328458A1 (xx) |
| GB (1) | GB1497500A (xx) |
| GR (1) | GR61598B (xx) |
| HU (1) | HU174097B (xx) |
| IE (1) | IE43745B1 (xx) |
| IL (1) | IL50732A (xx) |
| LU (1) | LU76057A1 (xx) |
| NL (1) | NL7611683A (xx) |
| NO (1) | NO143844C (xx) |
| PL (2) | PL110002B1 (xx) |
| PT (1) | PT65737B (xx) |
| RO (1) | RO76883A (xx) |
| SE (1) | SE432926B (xx) |
| SU (2) | SU639443A3 (xx) |
| ZA (1) | ZA766303B (xx) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1223395B (it) * | 1987-12-01 | 1990-09-19 | Simes | Composti ad attivita' cardiovascolare |
| US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
| BRPI0810063A2 (pt) * | 2007-04-20 | 2014-10-14 | Acucela Inc | Composto, composição farmacêutica, e, métodos para modular fluxo de cromóforo em um ciclo retinóide, para tratar uma doença ou distúrbio oftálmico em um indivíduo, para inibir adaptação ao escuro em uma célula fotorreceptora de bastão da retina, para inibir regeneração de rodopsina em uma célula fotoreceptora de bastão da retina, para reduzir isquemia em um olho de um indivíduo, para inibir neovascularização na retina de um olho de um indivíduo, e para inibir degeneração de uma célula da retina em uma retina |
| FR3030514A1 (fr) * | 2014-12-18 | 2016-06-24 | Centre De Coop Int En Rech Agronomique Pour Le Dev (Cirad) | Dimeres polyaromatiques |
| EP3144289A1 (en) * | 2015-09-16 | 2017-03-22 | Evonik Technochemie GmbH | [(2-ethoxy-5-trans-1-propen-1-yl)-phenoxyl]-terminated compounds |
| CN110035745B (zh) * | 2016-10-05 | 2022-04-29 | 匹兹堡大学联邦系统高等教育 | 小分子ampk活化剂 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3758583A (en) * | 1971-01-21 | 1973-09-11 | Syntex Corp | 2-(2-hydroxy-3-aminopropyl-1-yloxy)-1,6-dilfuoro-and-1,6-methano-{8 10{9 annulenes and the salts thereof |
-
1975
- 1975-10-23 DE DE19752547524 patent/DE2547524A1/de not_active Withdrawn
-
1976
- 1976-10-08 NO NO763442A patent/NO143844C/no unknown
- 1976-10-13 US US05/732,118 patent/US4110472A/en not_active Expired - Lifetime
- 1976-10-18 SU SU762413401A patent/SU639443A3/ru active
- 1976-10-18 CH CH1318976A patent/CH623562A5/de not_active IP Right Cessation
- 1976-10-19 BG BG035324A patent/BG31796A3/xx unknown
- 1976-10-19 AU AU18797/76A patent/AU502167B2/en not_active Expired
- 1976-10-19 BG BG034473A patent/BG27732A3/xx unknown
- 1976-10-20 IL IL50732A patent/IL50732A/xx unknown
- 1976-10-20 PT PT65737A patent/PT65737B/pt unknown
- 1976-10-21 AT AT784476A patent/AT344682B/de not_active IP Right Cessation
- 1976-10-21 JP JP51125582A patent/JPS5935387B2/ja not_active Expired
- 1976-10-21 NL NL7611683A patent/NL7611683A/xx not_active Application Discontinuation
- 1976-10-21 HU HU76BA3468A patent/HU174097B/hu unknown
- 1976-10-21 FI FI763010A patent/FI67075C/fi not_active IP Right Cessation
- 1976-10-21 SE SE7611686A patent/SE432926B/xx unknown
- 1976-10-21 DD DD7600195393A patent/DD128555A5/xx unknown
- 1976-10-21 AT AT606377A patent/AT345792B/de not_active IP Right Cessation
- 1976-10-21 GB GB43725/76A patent/GB1497500A/en not_active Expired
- 1976-10-22 BE BE171708A patent/BE847541A/xx not_active IP Right Cessation
- 1976-10-22 RO RO7696832A patent/RO76883A/ro unknown
- 1976-10-22 CS CS777809A patent/CS191344B2/cs unknown
- 1976-10-22 LU LU76057A patent/LU76057A1/xx unknown
- 1976-10-22 CS CS766837A patent/CS191322B2/cs unknown
- 1976-10-22 FR FR7631948A patent/FR2328458A1/fr active Granted
- 1976-10-22 PL PL1976213281A patent/PL110002B1/pl unknown
- 1976-10-22 ES ES452616A patent/ES452616A1/es not_active Expired
- 1976-10-22 ZA ZA766303A patent/ZA766303B/xx unknown
- 1976-10-22 DK DK480376A patent/DK480376A/da not_active Application Discontinuation
- 1976-10-22 CA CA263,964A patent/CA1085417A/en not_active Expired
- 1976-10-22 PL PL1976193206A patent/PL110007B1/pl unknown
- 1976-10-22 IE IE2332/76A patent/IE43745B1/en unknown
- 1976-10-22 GR GR51997A patent/GR61598B/el unknown
-
1977
- 1977-07-15 SU SU772502200A patent/SU664559A3/ru active
-
1980
- 1980-09-08 CH CH672680A patent/CH630058A5/de not_active IP Right Cessation
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