CR8811A - Compuestos de opioide carboxamido - Google Patents

Compuestos de opioide carboxamido

Info

Publication number
CR8811A
CR8811A CR8811A CR8811A CR8811A CR 8811 A CR8811 A CR 8811A CR 8811 A CR8811 A CR 8811A CR 8811 A CR8811 A CR 8811A CR 8811 A CR8811 A CR 8811A
Authority
CR
Costa Rica
Prior art keywords
opioid
carboxamido compounds
modulating
disorder
treating
Prior art date
Application number
CR8811A
Other languages
English (en)
Inventor
R Carson John
M Pitis Philip
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35064532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR8811(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CR8811A publication Critical patent/CR8811A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Esta invencion se refiere a compuestos opioides de carboxamido que son farmaceuticamente utiles como agentes para tratar o para modular un trastorno del sistema nervioso centarl y metodos para tratar o para modular un transtorno del sistema nervioso central.
CR8811A 2004-05-14 2006-12-13 Compuestos de opioide carboxamido CR8811A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57129804P 2004-05-14 2004-05-14

Publications (1)

Publication Number Publication Date
CR8811A true CR8811A (es) 2009-01-14

Family

ID=35064532

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8811A CR8811A (es) 2004-05-14 2006-12-13 Compuestos de opioide carboxamido

Country Status (22)

Country Link
US (2) US7244866B2 (es)
EP (1) EP1748978B1 (es)
JP (1) JP5420170B2 (es)
KR (1) KR101204751B1 (es)
CN (1) CN1984879B (es)
AR (1) AR049276A1 (es)
AU (1) AU2005245403B2 (es)
BR (1) BRPI0511137A (es)
CA (1) CA2566601C (es)
CR (1) CR8811A (es)
EA (1) EA013261B1 (es)
EC (1) ECSP067008A (es)
ES (1) ES2485867T3 (es)
HK (1) HK1101246A1 (es)
IL (1) IL179196A (es)
MX (1) MXPA06013270A (es)
NO (1) NO20065768L (es)
NZ (1) NZ551288A (es)
TW (1) TWI418345B (es)
UA (1) UA90432C2 (es)
WO (1) WO2005113486A1 (es)
ZA (1) ZA200610446B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060254029A1 (en) * 2005-05-11 2006-11-16 Conrad Swenson Pocket loss prevention device
WO2005113486A1 (en) * 2004-05-14 2005-12-01 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
MX2009012685A (es) * 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
JP5555890B2 (ja) * 2009-03-19 2014-07-23 アルカーメス ファーマ アイルランド リミテッド 高い経口バイオアベイラビリティを有するモルフィナン誘導体
RS58894B1 (sr) * 2009-12-04 2019-08-30 Alkermes Pharma Ireland Ltd Derivati morfinana za lečenje predoziranja lekom
HUE041981T2 (hu) 2010-08-23 2019-06-28 Alkermes Pharma Ireland Ltd Eljárások antipszichotikum által kiváltott súlygyarapodás kezelésére
US9029543B2 (en) 2011-04-05 2015-05-12 Alkermes, Inc. Process for the synthesis of quaternary amine compounds
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
MX2014007042A (es) 2011-12-15 2015-01-22 Alkermes Pharma Ireland Ltd Composiciones de la buprenorfina y antagonistas de los receptores opioide-mu.
US9656961B2 (en) 2013-05-24 2017-05-23 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
CN104940709A (zh) * 2015-07-22 2015-09-30 张秋英 一种镇痛麻醉喷雾剂
CN105055756A (zh) * 2015-09-18 2015-11-18 张秋英 一种阴部挫伤用镇痛气雾剂
EP3570838B1 (en) 2017-01-17 2024-06-05 Mebias Discovery, Inc. Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0507863A4 (en) * 1989-12-28 1993-07-07 Virginia Commonwealth University Sigma receptor ligands and the use thereof
US6071970A (en) * 1993-02-08 2000-06-06 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
DE4426245A1 (de) * 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE60109960T2 (de) * 2000-10-31 2006-02-16 Rensselaer Polytechnic Institute 8-substituierte 2,6-methano-3-benzazocine und 3-substituierte morphinane als opioidrezeptorbindende agenzien
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
AU2002364517A1 (en) * 2001-11-30 2003-06-17 Sepracor Inc. Tramadol analogs and uses thereof
DE10213051B4 (de) 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
AR045972A1 (es) * 2002-10-25 2005-11-23 Labopharm Inc Formulaciones de tramadol de liberacion sostenida con eficacia de 24 horas
ME02221B (me) 2004-03-15 2016-02-20 Janssen Pharmaceutica Nv Postupak za proizvodnju intermedijara jedinjenja korisnih kao modulatori opioidnih receptora
WO2005113486A1 (en) * 2004-05-14 2005-12-01 Janssen Pharmaceutica N.V. Carboxamido opioid compounds

Also Published As

Publication number Publication date
ES2485867T3 (es) 2014-08-14
IL179196A0 (en) 2007-03-08
EP1748978A1 (en) 2007-02-07
CA2566601C (en) 2013-04-09
CA2566601A1 (en) 2005-12-01
TW200605871A (en) 2006-02-16
MXPA06013270A (es) 2007-04-23
EA200602115A1 (ru) 2007-04-27
AU2005245403B2 (en) 2012-04-19
US20080280990A1 (en) 2008-11-13
HK1101246A1 (en) 2007-10-12
KR20070015613A (ko) 2007-02-05
NO20065768L (no) 2007-02-07
JP5420170B2 (ja) 2014-02-19
AU2005245403A1 (en) 2005-12-01
CN1984879A (zh) 2007-06-20
US7244866B2 (en) 2007-07-17
JP2007537278A (ja) 2007-12-20
AR049276A1 (es) 2006-07-12
NZ551288A (en) 2010-10-29
ECSP067008A (es) 2006-12-29
US20050256203A1 (en) 2005-11-17
UA90432C2 (uk) 2010-04-26
BRPI0511137A (pt) 2007-11-27
IL179196A (en) 2012-10-31
US7745492B2 (en) 2010-06-29
WO2005113486A1 (en) 2005-12-01
ZA200610446B (en) 2008-07-30
KR101204751B1 (ko) 2012-11-27
TWI418345B (zh) 2013-12-11
EP1748978B1 (en) 2014-06-04
EA013261B1 (ru) 2010-04-30
CN1984879B (zh) 2011-07-27

Similar Documents

Publication Publication Date Title
CR8811A (es) Compuestos de opioide carboxamido
CR10310A (es) Compuestos nuevos
BRPI0808775A2 (pt) compostos e composições como moduladores de atividade de gpr119
CR11292A (es) Compuestos y composiciones como moduladores de la actividad de gpr119
MX2009007944A (es) Compuestos y composiciones de purina como inhibidores de quinasa para el tratamiento de enfermedades relacionadas con plasmodium.
BRPI0517015A (pt) compostos e composições como inibidores de atividade de receptor 1 de canabinóide
TW200745109A (en) Pyrrolo-pyridine kinase modulators
TNSN07027A1 (en) Pyrrolo-pyridine kinase modulators
MX2009004047A (es) Compuestos organicos.
ECSP088852A (es) Azolopirimidinas como inhibidores de la actividad canabinoidea 1
CR20130640A (es) Métodos para tratar o prevenir trastornos relacionados con el colesterol
CR10277A (es) Pirazolquinolonas como potentes inhibidores de parp
TW200942533A (en) Pyridyl inhibitors of hedgehog signalling
NI200300039A (es) Compuestos que modulan la actividad de ppar.
PA8568701A1 (es) Compuestos que modulan la actividad de ppar
MX2010002732A (es) Inhibidores de f1f0-atpasa y metodos relacionados.
CO6361927A2 (es) Quinazolinas para inhibicion de pdk1
HN2009000018A (es) Inhibidores de tirosina quinasa
IN2012DN02471A (es)
TW200733976A (en) Method for the treatment of cognitive dysfunction
EA201001330A1 (ru) Соединения и композиции в качестве модуляторов активности gpr119
UY29161A1 (es) Nuevos heterociclos
HN2003000080A (es) Indolil-urea derivados de tienopiridinas utiles como agentes antiangiogenicos y procedimientos para su uso
TW200716132A (en) Novel chemical compounds
AR060088A1 (es) Metodos para tratar trastornos cognitivos y otros afines

Legal Events

Date Code Title Description
FC Refusal