CR8811A - Compuestos de opioide carboxamido - Google Patents

Compuestos de opioide carboxamido

Info

Publication number
CR8811A
CR8811A CR8811A CR8811A CR8811A CR 8811 A CR8811 A CR 8811A CR 8811 A CR8811 A CR 8811A CR 8811 A CR8811 A CR 8811A CR 8811 A CR8811 A CR 8811A
Authority
CR
Costa Rica
Prior art keywords
opioid
carboxamido compounds
modulating
disorder
treating
Prior art date
Application number
CR8811A
Other languages
English (en)
Inventor
R Carson John
M Pitis Philip
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35064532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR8811(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CR8811A publication Critical patent/CR8811A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Esta invencion se refiere a compuestos opioides de carboxamido que son farmaceuticamente utiles como agentes para tratar o para modular un trastorno del sistema nervioso centarl y metodos para tratar o para modular un transtorno del sistema nervioso central.
CR8811A 2004-05-14 2006-12-13 Compuestos de opioide carboxamido CR8811A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57129804P 2004-05-14 2004-05-14

Publications (1)

Publication Number Publication Date
CR8811A true CR8811A (es) 2009-01-14

Family

ID=35064532

Family Applications (1)

Application Number Title Priority Date Filing Date
CR8811A CR8811A (es) 2004-05-14 2006-12-13 Compuestos de opioide carboxamido

Country Status (22)

Country Link
US (2) US7244866B2 (es)
EP (1) EP1748978B1 (es)
JP (1) JP5420170B2 (es)
KR (1) KR101204751B1 (es)
CN (1) CN1984879B (es)
AR (1) AR049276A1 (es)
AU (1) AU2005245403B2 (es)
BR (1) BRPI0511137A (es)
CA (1) CA2566601C (es)
CR (1) CR8811A (es)
EA (1) EA013261B1 (es)
EC (1) ECSP067008A (es)
ES (1) ES2485867T3 (es)
HK (1) HK1101246A1 (es)
IL (1) IL179196A (es)
MX (1) MXPA06013270A (es)
NO (1) NO20065768L (es)
NZ (1) NZ551288A (es)
TW (1) TWI418345B (es)
UA (1) UA90432C2 (es)
WO (1) WO2005113486A1 (es)
ZA (1) ZA200610446B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060254029A1 (en) * 2005-05-11 2006-11-16 Conrad Swenson Pocket loss prevention device
AU2005245403B2 (en) * 2004-05-14 2012-04-19 Janssen Pharmaceutica N.V. Carboxamido opioid compounds
CN101686672A (zh) * 2007-05-31 2010-03-31 塞普拉柯公司 苯基取代的环烷胺作为一元胺再摄取抑制剂
CA2754984C (en) * 2009-03-19 2018-06-26 Alkermes, Inc. Morphinan derivatives with high oral bioavailability
ME03468B (me) * 2009-12-04 2020-01-20 Alkermes Pharma Ireland Ltd Derivati morfinana za liječenje predoziranja lijekom
AU2011293502B2 (en) 2010-08-23 2015-03-19 Alkermes Pharma Ireland Limited Methods for treating antipsychotic-induced weight gain
US9029543B2 (en) 2011-04-05 2015-05-12 Alkermes, Inc. Process for the synthesis of quaternary amine compounds
KR101996108B1 (ko) 2011-12-15 2019-10-01 엘커메스 파마 아일랜드 리미티드 부프레놀핀 및 뮤-오피오이드 수용체 길항물질의 조성물
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
WO2014190271A2 (en) 2013-05-24 2014-11-27 Alkermes Pharma Ireland Limted Methods for treating depressive symptoms
AU2014268361B2 (en) 2013-05-24 2018-09-06 Alkermes Pharma Ireland Limited Morphan and morphinan analogues, and methods of use
CN104940709A (zh) * 2015-07-22 2015-09-30 张秋英 一种镇痛麻醉喷雾剂
CN105055756A (zh) * 2015-09-18 2015-11-18 张秋英 一种阴部挫伤用镇痛气雾剂
EP3570838B1 (en) 2017-01-17 2024-06-05 Mebias Discovery, Inc. Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same
EP4243768A1 (en) 2020-11-12 2023-09-20 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2071897A1 (en) 1989-12-28 1991-06-29 Richard A. Glennon Sigma receptor ligands and the use thereof
US6071970A (en) 1993-02-08 2000-06-06 Nps Pharmaceuticals, Inc. Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
DE60133584T2 (de) * 2000-10-31 2009-06-04 Rensselaer Polytechnic Institute 4-arylpiperidine als opioidrezeptorbindende agenzien
DE10059413A1 (de) * 2000-11-30 2002-06-20 Gruenenthal Gmbh Verwendung von substituierten 6-Dimethylaminomethyl-1-phenyl-cyclohexanverbindungen zur Therapie der Harninkontinenz
DE10146275A1 (de) * 2001-09-18 2003-04-24 Gruenenthal Gmbh Kombination ausgewählter Opioide mit Muscarin-Antagonisten zur Therapie der Harninkontinenz
WO2003048113A1 (en) * 2001-11-30 2003-06-12 Sepracor Inc. Tramadol analogs and uses thereof
DE10213051B4 (de) 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
KR20050083816A (ko) * 2002-10-25 2005-08-26 라보팜 인코포레이트 24시간 효능의 서방 트라마돌 조성물
PT2573068E (pt) 2004-03-15 2015-04-27 Janssen Pharmaceutica Nv Processo para a preparação de intermediários de compostos úteis como moduladores do recetor opióide
AU2005245403B2 (en) * 2004-05-14 2012-04-19 Janssen Pharmaceutica N.V. Carboxamido opioid compounds

Also Published As

Publication number Publication date
ECSP067008A (es) 2006-12-29
EP1748978A1 (en) 2007-02-07
WO2005113486A1 (en) 2005-12-01
NO20065768L (no) 2007-02-07
AU2005245403A1 (en) 2005-12-01
US20080280990A1 (en) 2008-11-13
KR101204751B1 (ko) 2012-11-27
TW200605871A (en) 2006-02-16
CN1984879A (zh) 2007-06-20
EA013261B1 (ru) 2010-04-30
US7745492B2 (en) 2010-06-29
US7244866B2 (en) 2007-07-17
IL179196A0 (en) 2007-03-08
EP1748978B1 (en) 2014-06-04
ES2485867T3 (es) 2014-08-14
MXPA06013270A (es) 2007-04-23
CN1984879B (zh) 2011-07-27
HK1101246A1 (en) 2007-10-12
TWI418345B (zh) 2013-12-11
JP5420170B2 (ja) 2014-02-19
EA200602115A1 (ru) 2007-04-27
UA90432C2 (uk) 2010-04-26
AU2005245403B2 (en) 2012-04-19
ZA200610446B (en) 2008-07-30
US20050256203A1 (en) 2005-11-17
CA2566601C (en) 2013-04-09
IL179196A (en) 2012-10-31
CA2566601A1 (en) 2005-12-01
JP2007537278A (ja) 2007-12-20
NZ551288A (en) 2010-10-29
KR20070015613A (ko) 2007-02-05
AR049276A1 (es) 2006-07-12
BRPI0511137A (pt) 2007-11-27

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