CR6106A - Desnaturalizantes para sales aminas simpaticomimeticas - Google Patents
Desnaturalizantes para sales aminas simpaticomimeticasInfo
- Publication number
- CR6106A CR6106A CR6106A CR6106A CR6106A CR 6106 A CR6106 A CR 6106A CR 6106 A CR6106 A CR 6106A CR 6106 A CR6106 A CR 6106A CR 6106 A CR6106 A CR 6106A
- Authority
- CR
- Costa Rica
- Prior art keywords
- sympathomimetic amine
- denaturants
- amine salts
- combination
- interfere
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Composiciones farmaceuticas que comprenden una sal de amina simpaticomimetica y al menos un inhibidor de combinacion, el inhibidor de combinacion que actua tanto para interferir en el aislamiento de la amina simpaticomimetica de la composicion como para interferir en la conversion de la amina simpaticomimetica en otro compuesto farmacologicamente activo. Las composiciones contempladas tambien pueden incluir inhibidores de reaccion y de separacion en cualquier mezcla para asegurar la maxima proteccion contra el uso de composiciones que contienen amina simpaticomimetica para la fabricacion ilegal de drogas. La presencia de los inhibidores de combinacion, reaccion y separacion no altera de manera significativa la liberacion de la amina simpaticomimetica de la composicion.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9971298P | 1998-09-10 | 1998-09-10 | |
US09/391,739 US6359011B1 (en) | 1998-09-10 | 1999-09-08 | Denaturants for sympathomimetic amine salts |
Publications (1)
Publication Number | Publication Date |
---|---|
CR6106A true CR6106A (es) | 2003-12-05 |
Family
ID=22276270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR6106A CR6106A (es) | 1998-09-10 | 1999-09-09 | Desnaturalizantes para sales aminas simpaticomimeticas |
Country Status (22)
Country | Link |
---|---|
US (4) | US6359011B1 (es) |
EP (1) | EP1112089A1 (es) |
JP (1) | JP2002524534A (es) |
KR (1) | KR20010075021A (es) |
CN (1) | CN1201822C (es) |
AR (1) | AR032730A1 (es) |
AU (2) | AU771194B2 (es) |
BR (1) | BR9913575A (es) |
CA (1) | CA2339354A1 (es) |
CO (1) | CO5280050A1 (es) |
CR (1) | CR6106A (es) |
GT (1) | GT199900148A (es) |
HK (1) | HK1039898A1 (es) |
HN (1) | HN1999000156A (es) |
MY (1) | MY117971A (es) |
NZ (1) | NZ510012A (es) |
PA (1) | PA8481601A1 (es) |
PE (1) | PE20001034A1 (es) |
SV (1) | SV1999000148A (es) |
TW (1) | TW550071B (es) |
UY (1) | UY25702A1 (es) |
WO (1) | WO2000015261A1 (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GT199900148A (es) * | 1998-09-10 | 2001-02-28 | Desnaturalizantes para las sales aminas simpaticomimeticas. | |
MXPA03000520A (es) * | 2000-07-17 | 2003-10-06 | Yamanouchi Pharma Co Ltd | Composicion farmaceutica mejorada en absorbabilidad peroral.. |
EP2298279B1 (en) * | 2000-11-30 | 2018-11-14 | Vectura Limited | Pharmaceutical compositions for inhalation |
ITMI20021074A1 (it) * | 2002-05-20 | 2003-11-20 | Actimex S R L | Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione |
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
US20050220877A1 (en) * | 2004-03-31 | 2005-10-06 | Patel Ashish A | Bilayer tablet comprising an antihistamine and a decongestant |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102004045037A1 (de) * | 2004-09-15 | 2006-03-16 | Basf Ag | Pharmazeutische Darreichungsformen mit erschwerter Extrahierbarkeit eines Sympathomimetikums aus der Darreichungsform |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
EP1978940B1 (en) * | 2006-01-19 | 2010-12-29 | Dow Global Technologies Inc. | Biologically active composition comprising ethylcellulose |
US9238073B2 (en) | 2006-04-12 | 2016-01-19 | Wyeth Llc | Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive |
US8273798B2 (en) * | 2007-06-04 | 2012-09-25 | Shear Kershman Laboratories | Tamper resistant lipid-based oral dosage form for opioid agonists |
WO2009012590A1 (en) * | 2007-07-23 | 2009-01-29 | Kingsway Pharmaceuticals Inc. | Therapeutic formulations for the treatment of cold and flu-like symptoms |
US9072670B2 (en) * | 2007-10-19 | 2015-07-07 | Otsuka Pharmaceutical Co., Ltd. | Matrix-type pharmaceutical solid preparation |
AR077420A1 (es) | 2009-07-22 | 2011-08-24 | Gruenenthal Gmbh | Forma de dosificacion resistente a la manipulacion para opiaceos sensibles a la oxidacion |
EP3064064A1 (en) * | 2009-09-30 | 2016-09-07 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
LT2736495T (lt) | 2011-07-29 | 2017-11-10 | Grünenthal GmbH | Sugadinimui atspari tabletė, pasižyminti greitu vaisto atpalaidavimu |
RS56527B1 (sr) | 2011-07-29 | 2018-02-28 | Gruenenthal Gmbh | Tableta za trenutno oslobađanje leka rezistentna na zloupotrebu |
WO2013036567A2 (en) * | 2011-09-07 | 2013-03-14 | Johnson Brent A | Methods, compositions, and compounds for the reduction of illegal methamphetamine production |
WO2013089986A1 (en) * | 2011-12-12 | 2013-06-20 | Product And Technology Partners Llc | Improved denaturants for sympathomimetic amines |
WO2014022541A1 (en) * | 2012-08-01 | 2014-02-06 | Acura Pharmaceuticals, Inc. | Stabilization of one-pot methamphetamine synthesis systems |
CN107595793B (zh) | 2012-11-30 | 2020-11-13 | 阿库拉制药公司 | 活性药物成分的自调节释放 |
CA2916973A1 (en) * | 2013-07-03 | 2015-01-08 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
MX368846B (es) | 2013-07-12 | 2019-10-18 | Gruenenthal Gmbh | Forma de dosificación resistente a la alteración que contiene polímero de acetato de etilen-vinilo. |
EP3073994A1 (en) | 2013-11-26 | 2016-10-05 | Grünenthal GmbH | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
CA2943728C (en) | 2014-03-26 | 2020-03-24 | Sun Pharma Advanced Research Company Ltd. | Abuse deterrent immediate release biphasic matrix solid dosage form |
WO2017040607A1 (en) | 2015-08-31 | 2017-03-09 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
JP2018526414A (ja) * | 2015-09-10 | 2018-09-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 乱用抑止性の即放性製剤を用いた経口過剰摂取に対する保護 |
TW202002957A (zh) | 2018-02-09 | 2020-01-16 | 德商歌林達有限公司 | 包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3169092A (en) | 1963-09-26 | 1965-02-09 | Richardson Merrell Inc | Stabilization of amines by tartrazine and bisulfite |
US3546142A (en) * | 1967-01-19 | 1970-12-08 | Amicon Corp | Polyelectrolyte structures |
US3773920A (en) * | 1971-07-14 | 1973-11-20 | Nikken Chemicals Co Ltd | Sustained release medicinal composition |
GB1593261A (en) | 1976-07-23 | 1981-07-15 | Inveresk Res Int | Controlled release suppository |
RO68771A2 (ro) * | 1976-08-25 | 1980-08-15 | Intreprinderea De Medicamente,Ro | Unguent antipruriginos si sicativ |
SU1146046A1 (ru) | 1983-11-11 | 1985-03-23 | Центральный Ордена Ленина Институт Усовершенствования Врачей | Состав дл ретракции десны |
US4493827A (en) | 1983-11-14 | 1985-01-15 | Ronald Valle | Method of inducing sleep |
US4601894A (en) * | 1985-03-29 | 1986-07-22 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
US4657757A (en) | 1985-03-29 | 1987-04-14 | Schering Corporation | Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate |
US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
US4894239A (en) | 1987-06-02 | 1990-01-16 | Takeda Chemical Industries, Ltd. | Sustained-release preparation and production thereof |
ZA904021B (en) | 1989-11-24 | 1991-02-27 | Van Der Linde Leon | Slimming preparations |
CA2068402C (en) | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
US5407686A (en) | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
US5518730A (en) * | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
WO1994028870A1 (en) | 1993-06-04 | 1994-12-22 | Warner-Lambert Company | Preparations containing silicon dioxide to improve the taste thereof |
US5543405A (en) * | 1993-10-22 | 1996-08-06 | Keown; Wendy J. | Composition and method for weight reduction and long term management of obesity |
AUPM814994A0 (en) | 1994-09-14 | 1994-10-06 | Sterling Winthrop Inc. | Codeine-containing formulations |
US5529783A (en) | 1994-12-19 | 1996-06-25 | Mcneil-Ppc, Inc. | Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan |
US5626878A (en) * | 1995-01-10 | 1997-05-06 | Warner Lambert Company | Reduction of electrostatic forces between magnesium trisilicate adsorbates |
ES2202605T3 (es) | 1996-04-10 | 2004-04-01 | Warner-Lambert Company Llc | Desnaturalizantes para sales de aminas simpatomimeticas. |
GT199900148A (es) * | 1998-09-10 | 2001-02-28 | Desnaturalizantes para las sales aminas simpaticomimeticas. |
-
1999
- 1999-09-07 GT GT199900148A patent/GT199900148A/es unknown
- 1999-09-08 US US09/391,739 patent/US6359011B1/en not_active Expired - Lifetime
- 1999-09-08 MY MYPI99003873A patent/MY117971A/en unknown
- 1999-09-09 UY UY25702A patent/UY25702A1/es not_active Application Discontinuation
- 1999-09-09 CO CO99057123A patent/CO5280050A1/es not_active Application Discontinuation
- 1999-09-09 WO PCT/US1999/020708 patent/WO2000015261A1/en not_active Application Discontinuation
- 1999-09-09 CA CA002339354A patent/CA2339354A1/en not_active Abandoned
- 1999-09-09 SV SV1999000148A patent/SV1999000148A/es not_active Application Discontinuation
- 1999-09-09 BR BR9913575-2A patent/BR9913575A/pt not_active Application Discontinuation
- 1999-09-09 PA PA19998481601A patent/PA8481601A1/es unknown
- 1999-09-09 CR CR6106A patent/CR6106A/es not_active Application Discontinuation
- 1999-09-09 AR ARP990104527A patent/AR032730A1/es unknown
- 1999-09-09 AU AU59157/99A patent/AU771194B2/en not_active Ceased
- 1999-09-09 PE PE1999000908A patent/PE20001034A1/es not_active Application Discontinuation
- 1999-09-09 HN HN1999000156A patent/HN1999000156A/es unknown
- 1999-09-09 CN CNB998107565A patent/CN1201822C/zh not_active Expired - Fee Related
- 1999-09-09 KR KR1020017003081A patent/KR20010075021A/ko not_active Application Discontinuation
- 1999-09-09 NZ NZ510012A patent/NZ510012A/xx unknown
- 1999-09-09 EP EP99946837A patent/EP1112089A1/en not_active Withdrawn
- 1999-09-09 JP JP2000569845A patent/JP2002524534A/ja active Pending
- 1999-09-10 TW TW088115613A patent/TW550071B/zh not_active IP Right Cessation
-
2001
- 2001-11-20 US US09/996,438 patent/US20020082304A1/en not_active Abandoned
-
2002
- 2002-02-26 HK HK02101442.0A patent/HK1039898A1/zh unknown
-
2004
- 2004-06-18 AU AU2004202702A patent/AU2004202702B2/en not_active Ceased
-
2005
- 2005-07-20 US US11/186,681 patent/US20050256194A1/en not_active Abandoned
-
2006
- 2006-06-02 US US11/445,967 patent/US20060216268A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HN1999000156A (es) | 2003-08-01 |
US20060216268A1 (en) | 2006-09-28 |
US20050256194A1 (en) | 2005-11-17 |
AU2004202702A1 (en) | 2004-07-15 |
BR9913575A (pt) | 2001-05-22 |
AU771194B2 (en) | 2004-03-18 |
CN1201822C (zh) | 2005-05-18 |
US20020082304A1 (en) | 2002-06-27 |
NZ510012A (en) | 2002-11-26 |
UY25702A1 (es) | 1999-11-17 |
PA8481601A1 (es) | 2001-04-30 |
SV1999000148A (es) | 2000-09-11 |
AR032730A1 (es) | 2003-11-26 |
EP1112089A1 (en) | 2001-07-04 |
CO5280050A1 (es) | 2003-05-30 |
US6359011B1 (en) | 2002-03-19 |
PE20001034A1 (es) | 2000-10-18 |
GT199900148A (es) | 2001-02-28 |
MY117971A (en) | 2004-08-30 |
CA2339354A1 (en) | 2000-03-23 |
CN1316911A (zh) | 2001-10-10 |
AU2004202702B2 (en) | 2007-11-22 |
HK1039898A1 (zh) | 2002-05-17 |
AU5915799A (en) | 2000-04-03 |
JP2002524534A (ja) | 2002-08-06 |
KR20010075021A (ko) | 2001-08-09 |
TW550071B (en) | 2003-09-01 |
WO2000015261A1 (en) | 2000-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal (granting procedure) |