CR11725A - Método para la producción de una enzima lisosomal recombinante humana en endoesperma de cereal - Google Patents

Método para la producción de una enzima lisosomal recombinante humana en endoesperma de cereal

Info

Publication number
CR11725A
CR11725A CR11725A CR11725A CR11725A CR 11725 A CR11725 A CR 11725A CR 11725 A CR11725 A CR 11725A CR 11725 A CR11725 A CR 11725A CR 11725 A CR11725 A CR 11725A
Authority
CR
Costa Rica
Prior art keywords
production
cereal
enzyme
human
endoesperma
Prior art date
Application number
CR11725A
Other languages
English (en)
Inventor
Marchetti Stefano
Bembi Bruno
Patti Tamara
Cristin Piero
Original Assignee
Transactiva Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transactiva Srl filed Critical Transactiva Srl
Publication of CR11725A publication Critical patent/CR11725A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a la producción de la enzima lisosoma recombinante humana bete-glucósidos ácida (E.C.3.2.1.45), mediante la transformación y manipulación genética de plantas, en particular de especies cereales. La especie preferentemente utilizada en esta invención es la Oryza Sativa L (arroz cultivado)
CR11725A 2008-03-13 2010-10-12 Método para la producción de una enzima lisosomal recombinante humana en endoesperma de cereal CR11725A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000055A ITUD20080055A1 (it) 2008-03-13 2008-03-13 Procedimento per la produzione di una proteina umana in pianta, in particolare un enzima lisosomiale umano ricombinante in endosperma di cereali

Publications (1)

Publication Number Publication Date
CR11725A true CR11725A (es) 2011-03-09

Family

ID=40293330

Family Applications (1)

Application Number Title Priority Date Filing Date
CR11725A CR11725A (es) 2008-03-13 2010-10-12 Método para la producción de una enzima lisosomal recombinante humana en endoesperma de cereal

Country Status (19)

Country Link
US (1) US20110038971A1 (es)
EP (1) EP2274432A1 (es)
JP (1) JP2011516036A (es)
KR (1) KR20100132516A (es)
CN (1) CN102027122A (es)
BR (1) BRPI0909336A2 (es)
CA (1) CA2717543A1 (es)
CO (1) CO6311018A2 (es)
CR (1) CR11725A (es)
EA (1) EA201071017A1 (es)
EC (1) ECSP10010543A (es)
GE (1) GEP20135914B (es)
IL (1) IL208010A0 (es)
IT (1) ITUD20080055A1 (es)
MA (1) MA32207B1 (es)
MX (1) MX2010010081A (es)
NI (1) NI201000152A (es)
NZ (1) NZ588516A (es)
WO (1) WO2009112508A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUD20130002A1 (it) * 2013-01-16 2014-07-17 Transactiva S R L Sequenza artificiale di dna avente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine ricombinanti in pianta e metodo per la produzione di proteine ricombinanti in pianta
KR101519402B1 (ko) * 2013-12-17 2015-05-13 강원대학교산학협력단 쌀눈 발아를 이용한 p53 항암 단백질 생산방법
CN104073492B (zh) * 2014-07-09 2016-06-22 安徽省农业科学院水稻研究所 一种作物糊粉层特异表达启动子PosAL1及其应用
KR101953950B1 (ko) * 2016-07-06 2019-05-17 전북대학교산학협력단 신호전달 펩타이드에 의한 액포수송벡터 개발
IT201700042052A1 (it) * 2017-04-14 2018-10-14 Transactiva S R L Vettore di espressione e metodo per la produzione di una proteina umana in pianta, in particolare un anticorpo ricombinante in endosperma di cereale
IT202100022157A1 (it) 2021-08-20 2023-02-20 Transactiva S R L Promotore sintetico per l’espressione di proteine eterologhe in pianta
EP4392570A2 (en) * 2021-08-25 2024-07-03 CANbridge Pharmaceuticals, Inc. Aav particles comprising liver-tropic capsid protein and acid alpha-glucosidase and use to treat pompe disease

Family Cites Families (17)

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US4251736A (en) * 1979-07-23 1981-02-17 United Technologies Corporation Method for controlling power flow between an electrochemical cell and a power grid
JPS6277833A (ja) * 1985-09-30 1987-04-10 株式会社東芝 自励式変換装置の制御方法
ZA94916B (en) * 1993-02-10 1995-08-10 Unilever Plc Immobilized proteins with specific binding capacities and their use in processes and products
US5760492A (en) * 1995-01-17 1998-06-02 Hitachi, Ltd. Control system for power transmission and distribution system
US5929304A (en) 1995-09-14 1999-07-27 Croptech Development Corporation Production of lysosomal enzymes in plant-based expression systems
IL155588A0 (en) * 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
IT1299565B1 (it) 1998-07-17 2000-03-16 Plantechno S R L Polinucleotide sintetico codificante per la lattoferrina umana, vettori, cellule e piante transgeniche che lo contengono.
US6900619B2 (en) * 1999-11-24 2005-05-31 American Superconductor Corporation Reactive power compensation to minimize step voltage changes and transients
JP3352662B2 (ja) * 2000-02-03 2002-12-03 関西電力株式会社 二次電池システムを用いた電力系統安定化装置および電力系統安定化方法
US7417178B2 (en) * 2000-05-02 2008-08-26 Ventria Bioscience Expression of human milk proteins in transgenic plants
US20030138769A1 (en) * 2000-08-16 2003-07-24 Birkett Ashley J. Immunogenic HBc chimer particles having enhanced stability
AU2002244071A1 (en) * 2001-02-14 2002-08-28 Ventria Bioscience Expression system for seed proteins
ITRM20020115A1 (it) * 2002-03-01 2003-09-01 Plantechno S R L Espressione di enzimi lisosomiali in seme.
US20070143872A1 (en) * 2003-08-27 2007-06-21 Orf Liftaekni Hf. Enhancing accumulation of heterologous polypeptides in plant seeds through targeted suppression of endogenous storage proteins
JP4019147B2 (ja) * 2003-10-31 2007-12-12 独立行政法人農業生物資源研究所 種子特異的プロモーターおよびその利用
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ITUD20060280A1 (it) * 2006-12-29 2008-06-30 Univ Degli Studi Udine Sequenza artificiale di dna evente funzione di leader in 5' (5'-utr) ottimizzata per la sovraespressione di proteine eterologhe in pianta

Also Published As

Publication number Publication date
ECSP10010543A (es) 2011-02-28
NI201000152A (es) 2011-03-24
EA201071017A1 (ru) 2011-06-30
MX2010010081A (es) 2011-03-04
CA2717543A1 (en) 2009-09-17
MA32207B1 (fr) 2011-04-01
JP2011516036A (ja) 2011-05-26
BRPI0909336A2 (pt) 2018-05-22
EP2274432A1 (en) 2011-01-19
WO2009112508A1 (en) 2009-09-17
CO6311018A2 (es) 2011-08-22
US20110038971A1 (en) 2011-02-17
NZ588516A (en) 2012-06-29
IL208010A0 (en) 2010-12-30
ITUD20080055A1 (it) 2009-09-14
KR20100132516A (ko) 2010-12-17
CN102027122A (zh) 2011-04-20
GEP20135914B (en) 2013-08-26

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FA Abandonment or withdrawal (granting procedure)