ATE532868T1 - Apoptose induzierende positivkontrolle für expressionsmodulationsexperimente - Google Patents

Apoptose induzierende positivkontrolle für expressionsmodulationsexperimente

Info

Publication number
ATE532868T1
ATE532868T1 AT08866218T AT08866218T ATE532868T1 AT E532868 T1 ATE532868 T1 AT E532868T1 AT 08866218 T AT08866218 T AT 08866218T AT 08866218 T AT08866218 T AT 08866218T AT E532868 T1 ATE532868 T1 AT E532868T1
Authority
AT
Austria
Prior art keywords
apoptosis
positive control
expression modulation
inducing positive
modulation experiments
Prior art date
Application number
AT08866218T
Other languages
English (en)
Inventor
Eric Lader
Original Assignee
Qiagen Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen Sciences Inc filed Critical Qiagen Sciences Inc
Application granted granted Critical
Publication of ATE532868T1 publication Critical patent/ATE532868T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111General methods applicable to biologically active non-coding nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00Applications; Uses
    • C12N2320/10Applications; Uses in screening processes
    • C12N2320/12Applications; Uses in screening processes in functional genomics, i.e. for the determination of gene function
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811Selection methods for production or design of target specific oligonucleotides or binding molecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT08866218T 2007-12-28 2008-12-29 Apoptose induzierende positivkontrolle für expressionsmodulationsexperimente ATE532868T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1732807P 2007-12-28 2007-12-28
PCT/IB2008/003644 WO2009083790A2 (en) 2007-12-28 2008-12-29 'apoptosis inducing positive control for expression modulating experiments'

Publications (1)

Publication Number Publication Date
ATE532868T1 true ATE532868T1 (de) 2011-11-15

Family

ID=40824794

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08866218T ATE532868T1 (de) 2007-12-28 2008-12-29 Apoptose induzierende positivkontrolle für expressionsmodulationsexperimente

Country Status (4)

Country Link
US (1) US8367320B2 (de)
EP (1) EP2235180B1 (de)
AT (1) ATE532868T1 (de)
WO (1) WO2009083790A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2075333A1 (de) * 2007-12-28 2009-07-01 Qiagen GmbH Positive Kontrollen für expressionsmodulierende Experimente
US20110136233A1 (en) * 2008-08-05 2011-06-09 Marina Biotech, Inc. Nucleic acid compounds for inhibiting plk1 gene expression and uses thereof
WO2011011700A2 (en) * 2009-07-24 2011-01-27 Curna, Inc. Treatment of sirtuin (sirt) related diseases by inhibition of natural antisense transcript to a sirtuin (sirt)
WO2011139710A1 (en) * 2010-04-26 2011-11-10 Marina Biotech, Inc. Nucleic acid compounds with conformationally restricted monomers and uses thereof
DE102011009470A1 (de) * 2011-01-21 2012-08-09 Friedrich-Schiller-Universität Jena Biologisch wirksame Nukleotid-Moleküle zur gezielten Abtötung von Zellen, Verwendung derselben sowie Applikationskit
ES2855577T3 (es) * 2011-03-30 2021-09-23 Transine Therapeutics Ltd Molécula de ácido nucleico funcional y uso de la misma
WO2012143427A1 (en) * 2011-04-19 2012-10-26 Santaris Pharma A/S Anti polyomavirus compounds
DE102012203542B4 (de) * 2012-03-07 2016-06-23 Zf Friedrichshafen Ag Verstellbares Dämpfventil

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005014811A2 (en) * 2003-08-08 2005-02-17 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF XIAP GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
WO2005047477A2 (en) * 2003-11-07 2005-05-26 University Of Massachusetts Interspersed repetitive element rnas as substrates, inhibitors and delivery vehicles for rnai
EP2075333A1 (de) * 2007-12-28 2009-07-01 Qiagen GmbH Positive Kontrollen für expressionsmodulierende Experimente

Also Published As

Publication number Publication date
US8367320B2 (en) 2013-02-05
WO2009083790A2 (en) 2009-07-09
EP2235180B1 (de) 2011-11-09
EP2235180A2 (de) 2010-10-06
WO2009083790A8 (en) 2010-02-18
US20100285484A1 (en) 2010-11-11
WO2009083790A3 (en) 2010-04-08

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