ATE534738T1 - Mir-126-regulierte gene und pfade als ziele für therapeutische interventionen - Google Patents

Mir-126-regulierte gene und pfade als ziele für therapeutische interventionen

Info

Publication number
ATE534738T1
ATE534738T1 AT07871691T AT07871691T ATE534738T1 AT E534738 T1 ATE534738 T1 AT E534738T1 AT 07871691 T AT07871691 T AT 07871691T AT 07871691 T AT07871691 T AT 07871691T AT E534738 T1 ATE534738 T1 AT E534738T1
Authority
AT
Austria
Prior art keywords
mir
pathways
targets
regulated genes
therapeutic interventions
Prior art date
Application number
AT07871691T
Other languages
English (en)
Inventor
Andreas G Bader
Mike Byrom
Charles D Johnson
David Brown
Original Assignee
Asuragen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asuragen Inc filed Critical Asuragen Inc
Application granted granted Critical
Publication of ATE534738T1 publication Critical patent/ATE534738T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT07871691T 2006-12-08 2007-12-10 Mir-126-regulierte gene und pfade als ziele für therapeutische interventionen ATE534738T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86929506P 2006-12-08 2006-12-08
US93956307P 2007-05-22 2007-05-22
PCT/US2007/087033 WO2008073921A2 (en) 2006-12-08 2007-12-10 Mir-126 regulated genes and pathways as targets for therapeutic intervention

Publications (1)

Publication Number Publication Date
ATE534738T1 true ATE534738T1 (de) 2011-12-15

Family

ID=39512447

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07871691T ATE534738T1 (de) 2006-12-08 2007-12-10 Mir-126-regulierte gene und pfade als ziele für therapeutische interventionen

Country Status (5)

Country Link
EP (1) EP2104736B1 (de)
AT (1) ATE534738T1 (de)
AU (1) AU2007333108A1 (de)
CA (1) CA2671296A1 (de)
WO (1) WO2008073921A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2219653B1 (de) 2007-11-09 2016-12-21 The Board of Regents of The University of Texas System Mikro-rnas der mir-15-familie zur modulierung des kardiomyozyten-überlebens und herzreparatur
EP2310507A4 (de) * 2008-07-08 2013-03-20 David Gladstone Inst Verfahren und zusammensetzungen zur angiogenesemodulierung
JP2012500199A (ja) * 2008-08-11 2012-01-05 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 血管統合性を促進するマイクロ−ｒｎａおよびその使用
SG175839A1 (en) 2009-04-30 2011-12-29 San Raffaele Centro Fond Gene vector
EP2327781A1 (de) 2009-11-27 2011-06-01 RWTH Aachen Mikro-RNA und Gewebereparatur
WO2013066368A1 (en) * 2011-10-03 2013-05-10 The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Use of mirna 126 to produce hematopoietic stem cells
WO2013152230A1 (en) 2012-04-04 2013-10-10 The Trustees Of Columbia University In The City Of New York Smooth muscle specific inhibition for anti-restenotic therapy
US9163235B2 (en) 2012-06-21 2015-10-20 MiRagen Therapeutics, Inc. Inhibitors of the miR-15 family of micro-RNAs
CN104830858A (zh) * 2015-03-05 2015-08-12 中国人民解放军第四军医大学 一种与浆液性卵巢癌发生发展机制相关的microRNA分子及其应用
CN113101368B (zh) * 2020-01-13 2022-10-21 中国医学科学院肿瘤医院 Slc7a8在食管鳞癌辅助诊断、癌前预警和靶向治疗中的应用
CN112760375A (zh) * 2020-08-04 2021-05-07 佛山科学技术学院 一种特征miRNA表达谱组合及子宫内膜癌早期预测方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1768139A (zh) * 2003-02-10 2006-05-03 独立行政法人产业技术总合研究所 通过dna干扰调控基因的表达
ES2534304T3 (es) * 2004-11-12 2015-04-21 Asuragen, Inc. Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN

Also Published As

Publication number Publication date
EP2104736B1 (de) 2011-11-23
WO2008073921A3 (en) 2009-02-26
CA2671296A1 (en) 2008-06-19
WO2008073921A2 (en) 2008-06-19
AU2007333108A1 (en) 2008-06-19
EP2104736A2 (de) 2009-09-30

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