CR11244A - Derivados de n-(arilamino) sulfonamidas que incluyen polimorfos como inhibidores de mek asi como composiciones, metodos de uso y de preparacion de los mismos - Google Patents
Derivados de n-(arilamino) sulfonamidas que incluyen polimorfos como inhibidores de mek asi como composiciones, metodos de uso y de preparacion de los mismosInfo
- Publication number
- CR11244A CR11244A CR11244A CR11244A CR11244A CR 11244 A CR11244 A CR 11244A CR 11244 A CR11244 A CR 11244A CR 11244 A CR11244 A CR 11244A CR 11244 A CR11244 A CR 11244A
- Authority
- CR
- Costa Rica
- Prior art keywords
- compositions
- methods
- mek
- compounds
- arilamino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/28—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
- A01N41/06—Sulfonic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Psychiatry (AREA)
- Plant Pathology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Rheumatology (AREA)
- Dentistry (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/830,733 US8101799B2 (en) | 2005-07-21 | 2007-07-30 | Derivatives of N-(arylamino) sulfonamides as inhibitors of MEK |
US3446408P | 2008-03-06 | 2008-03-06 | |
US3446608P | 2008-03-06 | 2008-03-06 | |
US4488608P | 2008-04-14 | 2008-04-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR11244A true CR11244A (es) | 2010-05-20 |
Family
ID=40304796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR11244A CR11244A (es) | 2007-07-30 | 2010-01-29 | Derivados de n-(arilamino) sulfonamidas que incluyen polimorfos como inhibidores de mek asi como composiciones, metodos de uso y de preparacion de los mismos |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP2184984A4 (fr) |
JP (3) | JP2010535232A (fr) |
KR (3) | KR20140098185A (fr) |
CN (2) | CN101808516B (fr) |
AP (1) | AP2817A (fr) |
AU (2) | AU2008282338B2 (fr) |
BR (1) | BRPI0815659A2 (fr) |
CA (1) | CA2693390C (fr) |
CO (1) | CO6470808A2 (fr) |
CR (1) | CR11244A (fr) |
DO (1) | DOP2010000045A (fr) |
EA (2) | EA032294B1 (fr) |
EC (1) | ECSP109910A (fr) |
HK (1) | HK1147396A1 (fr) |
HN (1) | HN2010000203A (fr) |
IL (1) | IL203296A (fr) |
MA (1) | MA31881B1 (fr) |
MX (1) | MX2010001244A (fr) |
NZ (1) | NZ582929A (fr) |
PH (1) | PH12015501914A1 (fr) |
SV (1) | SV2010003469A (fr) |
TN (1) | TN2010000049A1 (fr) |
WO (1) | WO2009018233A1 (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7723477B2 (en) | 2005-10-31 | 2010-05-25 | Oncomed Pharmaceuticals, Inc. | Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth |
US8808742B2 (en) * | 2008-04-14 | 2014-08-19 | Ardea Biosciences, Inc. | Compositions and methods for preparing and using same |
PL2334638T3 (pl) * | 2008-09-09 | 2019-04-30 | Hoffmann La Roche | Polimorfy acylosulfonoamidów |
SG190568A1 (en) | 2008-09-26 | 2013-06-28 | Oncomed Pharm Inc | Frizzled-binding agents and uses thereof |
CN103948600A (zh) | 2009-03-11 | 2014-07-30 | 阿迪生物科学公司 | 用于治疗特定癌症的包含rdea119/bay869766的药物组合 |
UY32486A (es) * | 2009-03-11 | 2010-10-29 | Ardea Biosciences Inc | Tratamiento del cáncer de páncreas |
ES2534358T3 (es) | 2009-10-13 | 2015-04-21 | Allomek Therapeutics, Llc | Inhibidores novedosos de MEK útiles en el tratamiento de enfermedades |
EP2491015A1 (fr) * | 2009-10-21 | 2012-08-29 | Bayer Pharma Aktiengesellschaft | Benzosulfonamides substitués |
TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Wnt拮抗劑及治療和篩選方法 |
CN102020651B (zh) | 2010-11-02 | 2012-07-18 | 北京赛林泰医药技术有限公司 | 6-芳基氨基吡啶酮甲酰胺mek抑制剂 |
CN102649773A (zh) * | 2011-02-23 | 2012-08-29 | 苏州波锐生物医药科技有限公司 | 氨基芳香烃类化合物及其在制备抗恶性肿瘤药物中的用途 |
NZ618062A (en) * | 2011-04-28 | 2016-04-29 | Sloan Kettering Inst Cancer | Hsp90 combination therapy |
ES2682247T3 (es) * | 2011-05-27 | 2018-09-19 | Ardea Biosciences, Inc. | Síntesis quiral de N-{3,4-difluoro-2-[(2-fluoro-4-yodofenil)amino]-6-metoxifenil}-1-[2,3-dihidroxi-propil]ciclopropanosulfonamidas |
US20150132301A1 (en) * | 2011-12-09 | 2015-05-14 | Oncomed Pharmaceuticals, Inc. | Combination Therapy for Treatment of Cancer |
WO2013109142A1 (fr) | 2012-01-16 | 2013-07-25 | Stichting Het Nederlands Kanker Instituut | Inhibition de la voie des mapk/erk et pdk combinée dans des cas de néoplasie |
BR112014029338A2 (pt) * | 2012-05-31 | 2017-06-27 | Bayer Pharma AG | biomarcadores para determinação da resposta eficaz dos tratamentos de pacientes com carcinoma hepatocelular (hcc) |
CN104736178A (zh) | 2012-06-04 | 2015-06-24 | 药品循环公司 | 布鲁顿酪氨酸激酶抑制剂的晶形 |
BR112015008623B1 (pt) * | 2012-10-19 | 2022-10-25 | Novartis Ag | Processos de preparação de (2-hidroxietióxi)-amida do ácido 6-(4-bromo-2-fluorfenilamino) -7-flúor-3-metil-3h-benzoimidazol-5-carboxílico cristalizado e seus intermediários |
AU2013337702A1 (en) | 2012-11-02 | 2015-05-21 | Merck Patent Gmbh | Method of reducing adverse effects in a cancer patient undergoing treatment with a MEK inhibitor |
US9359444B2 (en) | 2013-02-04 | 2016-06-07 | Oncomed Pharmaceuticals Inc. | Methods and monitoring of treatment with a Wnt pathway inhibitor |
EP2848246A1 (fr) | 2013-09-13 | 2015-03-18 | Bayer Pharma Aktiengesellschaft | Compositions pharmaceutiques contenant du refametinib |
WO2015041534A1 (fr) | 2013-09-20 | 2015-03-26 | Stichting Het Nederlands Kanker Instituut | P90rsk en combinaison avec raf/erk/mek |
US9629851B2 (en) | 2013-09-20 | 2017-04-25 | Stitching Het Nederlands Kanker Institut—Antoni Van Leeuwenhoek Ziekenhuis | ROCK in combination with MAPK pathway |
WO2015156674A2 (fr) | 2014-04-10 | 2015-10-15 | Stichting Het Nederlands Kanker Instituut | Méthode de traitement du cancer |
WO2015178770A1 (fr) | 2014-05-19 | 2015-11-26 | Stichting Het Nederlands Kanker Instituut | Compositions pour le traitement du cancer |
KR102425265B1 (ko) * | 2014-08-25 | 2022-07-26 | 에이뮨 테라퓨틱스, 인코퍼레이티드 | 난 단백질 제형 및 이의 제조 방법 |
JP7149076B2 (ja) | 2015-03-03 | 2022-10-06 | ファーマサイクリックス エルエルシー | ブルトン型チロシンキナーゼ阻害剤の薬学的製剤 |
KR20200016969A (ko) * | 2017-06-16 | 2020-02-17 | 베타 파마, 인크. | N-(2-(2-(디메틸아미노)에톡시)-4-메톡시-5-((4-(1-메틸-1h-인돌-3-일)피리미딘-2-일)아미노)페닐)아크릴아미드 및 그의 염의 제약 제제 |
EA202192575A1 (ru) | 2019-03-21 | 2022-01-14 | Онксео | Соединения dbait в сочетании с ингибиторами киназ для лечения рака |
US20220401436A1 (en) | 2019-11-08 | 2022-12-22 | INSERM (Institute National de la Santé et de la Recherche Médicale) | Methods for the treatment of cancers that have acquired resistance to kinase inhibitors |
WO2021148581A1 (fr) | 2020-01-22 | 2021-07-29 | Onxeo | Nouvelle molécule dbait et son utilisation |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5162117A (en) * | 1991-11-22 | 1992-11-10 | Schering Corporation | Controlled release flutamide composition |
JP2575590B2 (ja) * | 1992-07-31 | 1997-01-29 | 塩野義製薬株式会社 | トリアゾリルチオメチルチオセファロスポリン塩酸塩およびその水和物結晶ならびにそれらの製法 |
EP0810209B1 (fr) * | 1992-08-25 | 2002-06-05 | G.D. Searle & Co. | Sulfamides d'hydroxyéthylamino utiles comme inhibiteurs de protéases rétrovirales |
US7115632B1 (en) * | 1999-05-12 | 2006-10-03 | G. D. Searle & Co. | Sulfonyl aryl or heteroaryl hydroxamic acid compounds |
GEP20032999B (en) * | 1999-01-13 | 2003-06-25 | Warner Lambert Co | 1-Heterocycle Substituted Diarylamines |
GB0003224D0 (en) * | 2000-02-11 | 2000-04-05 | Glaxo Group Ltd | Chemical compounds |
US7235567B2 (en) * | 2000-06-15 | 2007-06-26 | Schering Corporation | Crystalline polymorph of a bisulfate salt of a thrombin receptor antagonist |
EP1429713A4 (fr) * | 2001-09-24 | 2007-08-08 | Jessie L S Au | Procedes et compositions permettant de determiner la dose de chimiosensibilisation de la suramine utilisee dans une therapie associative |
WO2004006909A1 (fr) * | 2002-07-17 | 2004-01-22 | Titan Pharmaceuticals, Inc. | Combinaison de medicaments chimiotherapeutiques visant a augmenter l'activite antitumorale |
KR101066804B1 (ko) * | 2002-07-30 | 2011-09-22 | 아에테르나 젠타리스 게엠베하 | 항종양 약제와 조합하여 사용하기 위한 알킬포스포콜린의 약물 제품 |
CA2604735A1 (fr) * | 2005-04-12 | 2006-10-19 | Elan Pharma International Limited | Formules de nanoparticules de derives de quinazoline |
JPWO2006115154A1 (ja) * | 2005-04-22 | 2008-12-18 | キッセイ薬品工業株式会社 | 4´−{2−[(1s,2r)−2−ヒドロキシ−2−(4−ヒドロキシフェニル)−1−メチルエチルアミノ]エトキシ}−3−イソプロピル−3´,5´−ジメチルビフェニルカルボン酸塩酸塩の結晶多形 |
CA2618218C (fr) * | 2005-07-21 | 2015-06-30 | Ardea Biosciences, Inc. | Inhibiteurs n-(arylamino)-sulfonamide de mek |
JP2007099763A (ja) * | 2005-09-08 | 2007-04-19 | Toyama Chem Co Ltd | ピペラシリンナトリウム・1水和物の新規な結晶及びその製造方法 |
TW200800150A (en) * | 2005-12-21 | 2008-01-01 | Organon Nv | Compounds with medicinal effects due to interaction with the glucocorticoid receptor |
-
2008
- 2008-07-28 EP EP08796733.7A patent/EP2184984A4/fr not_active Ceased
- 2008-07-28 AU AU2008282338A patent/AU2008282338B2/en not_active Ceased
- 2008-07-28 KR KR1020147017261A patent/KR20140098185A/ko not_active Application Discontinuation
- 2008-07-28 CN CN2008801088296A patent/CN101808516B/zh not_active Expired - Fee Related
- 2008-07-28 CN CN201310317815.8A patent/CN103479604B/zh not_active Expired - Fee Related
- 2008-07-28 AP AP2010005134A patent/AP2817A/xx active
- 2008-07-28 MX MX2010001244A patent/MX2010001244A/es active IP Right Grant
- 2008-07-28 KR KR1020157020493A patent/KR20150091434A/ko not_active Application Discontinuation
- 2008-07-28 JP JP2010520118A patent/JP2010535232A/ja active Pending
- 2008-07-28 EA EA201400552A patent/EA032294B1/ru not_active IP Right Cessation
- 2008-07-28 NZ NZ582929A patent/NZ582929A/en not_active IP Right Cessation
- 2008-07-28 EA EA201000268A patent/EA020624B1/ru not_active IP Right Cessation
- 2008-07-28 BR BRPI0815659-0A2A patent/BRPI0815659A2/pt not_active Application Discontinuation
- 2008-07-28 WO PCT/US2008/071392 patent/WO2009018233A1/fr active Application Filing
- 2008-07-28 CA CA2693390A patent/CA2693390C/fr not_active Expired - Fee Related
- 2008-07-28 KR KR1020107004742A patent/KR20100092424A/ko active Search and Examination
-
2010
- 2010-01-13 IL IL203296A patent/IL203296A/en not_active IP Right Cessation
- 2010-01-29 CO CO10009526A patent/CO6470808A2/es not_active Application Discontinuation
- 2010-01-29 SV SV2010003469A patent/SV2010003469A/es unknown
- 2010-01-29 DO DO2010000045A patent/DOP2010000045A/es unknown
- 2010-01-29 TN TNP2010000049A patent/TN2010000049A1/fr unknown
- 2010-01-29 CR CR11244A patent/CR11244A/es not_active Application Discontinuation
- 2010-01-29 EC EC2010009910A patent/ECSP109910A/es unknown
- 2010-01-29 HN HN2010000203A patent/HN2010000203A/es unknown
- 2010-02-19 MA MA32636A patent/MA31881B1/fr unknown
-
2011
- 2011-02-18 HK HK11101625.8A patent/HK1147396A1/xx not_active IP Right Cessation
-
2014
- 2014-11-14 JP JP2014231450A patent/JP6309880B2/ja not_active Expired - Fee Related
-
2015
- 2015-01-28 AU AU2015200390A patent/AU2015200390B2/en not_active Ceased
- 2015-08-28 PH PH12015501914A patent/PH12015501914A1/en unknown
-
2017
- 2017-02-03 JP JP2017018477A patent/JP2017125021A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CR11244A (es) | Derivados de n-(arilamino) sulfonamidas que incluyen polimorfos como inhibidores de mek asi como composiciones, metodos de uso y de preparacion de los mismos | |
UA99731C2 (ru) | Кристаллические полиморфные формы n-(ариламино)сульфонамидов как ингибиторы мэк, композиция (варианты) и применение | |
ECSP088749A (es) | Compuestos de tetrahidropiridotienopirimidina y procedimientos de uso de los mismos | |
UY29781A1 (es) | Compuestos diazaspiro sustituidos, sales farmacéuticamente aceptables, composiciones farmacéuticas que contienen los compuestos o sales, métodos de preparación y usos | |
UY29795A1 (es) | Derivados de adenina, composiciones farmacéuticas que los contienen, procesos de preparación y aplicaciones | |
UY31254A1 (es) | Derivados sutituidos de n4-(5-metil-1h-pirazol-3-il)- 1,3,5-triazina-2,4-diamina, sus enantiómeros, sales farmacéuticamente aceptables de los mismos, composiciones, procesos de preparación y aplicaciones | |
CR20110028A (es) | Derivados de pirimidina como inhibidores de cinasa | |
UY31524A1 (es) | Nuevos compuestos 010 | |
DOP2006000193A (es) | Compuestos de isoindol-imida y composiciones que los incluye y metodos para su uso | |
ECSP077268A (es) | Polimorfo ii de rapamicina y los usos de los mismos | |
UY30976A1 (es) | Nuevos derivados de quinolina, composiciones farmaccuticas que los contienen, procesos de preparacion y aplicaciones. | |
UY32611A (es) | Compuestos de 1-cianoetilheterociclilcarboxamida sustituidos 750 | |
CL2015002635A1 (es) | Compuestos y composiciones para el tratamiento de enfermedades parasitarias | |
CO6571916A2 (es) | Derivados de arilmetoxi isoindolina y composiciones que lo comprenden y métodos para utilizar los mismos | |
CR11861A (es) | Compuestos organicos | |
CL2007002733A1 (es) | Compuestos derivados de 2-aril-6-fenil-imidazo[1,2-a]piridinas; procedimiento de obtencion de los compuestos; composicion farmaceutica; y uso para el tratamiento y prevencion de enfermedades neurodegenerativas, osteoporosis y cancer. | |
UY28745A1 (es) | Nuevos compuestos | |
UY29803A1 (es) | Derivados de adeninas, composiciones farmacéuticas conteniéndolos, procedimientos de preparación y aplicaciones | |
UY29767A1 (es) | Derivados de benzotiazolonas, procesos para su preparación, composiciones farmacéuticas que los contienen y aplicaciones | |
EA201390908A1 (ru) | Производные бицикло[3.2.1]октиламида и их применение | |
ECSP109937A (es) | Pirimidil ciclopentanos como inhibidores de la proteína quinasa akt. | |
UY30748A1 (es) | Compuesto0s novedosos | |
UY31885A (es) | Derivados de las 1, 3, 5-triazina-2, 4-diaminas-6-sustituidas-n-sustituidas y sales farmacéuticamente aceptables de los mismos, composiciones y aplicaciones. | |
ECSP13012600A (es) | CO-cristales y Sales de Inhibidores de CCR3 | |
UY29685A1 (es) | Heterociclos de 1,4-dihidropiridina-condensados, procesos para preparar los mismos, uso y composiciones que los contienen. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |