CO6900146A2 - Imidazopiridazinas sustituidas con amino - Google Patents

Imidazopiridazinas sustituidas con amino

Info

Publication number
CO6900146A2
CO6900146A2 CO14048372A CO14048372A CO6900146A2 CO 6900146 A2 CO6900146 A2 CO 6900146A2 CO 14048372 A CO14048372 A CO 14048372A CO 14048372 A CO14048372 A CO 14048372A CO 6900146 A2 CO6900146 A2 CO 6900146A2
Authority
CO
Colombia
Prior art keywords
amino substituted
substituted imidazopyridazines
imidazopyridazines
amino
substituted
Prior art date
Application number
CO14048372A
Other languages
English (en)
Inventor
Knut Eis
Florian Puhler
Ludwig Zorn
Arne Scholz
Philip Lienau
Mark Jean Gnoth
Ulf Bomer
Judith Gunther
Marion Hitchcock
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47831558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6900146(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of CO6900146A2 publication Critical patent/CO6900146A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
CO14048372A 2011-09-06 2014-03-06 Imidazopiridazinas sustituidas con amino CO6900146A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11180129 2011-09-06
EP11182440 2011-09-23
EP12179902 2012-08-09

Publications (1)

Publication Number Publication Date
CO6900146A2 true CO6900146A2 (es) 2014-03-20

Family

ID=47831558

Family Applications (1)

Application Number Title Priority Date Filing Date
CO14048372A CO6900146A2 (es) 2011-09-06 2014-03-06 Imidazopiridazinas sustituidas con amino

Country Status (36)

Country Link
US (1) US9499547B2 (es)
EP (1) EP2758401B1 (es)
JP (1) JP6174583B2 (es)
KR (1) KR20140059268A (es)
CN (1) CN103958515B (es)
AP (1) AP2014007496A0 (es)
AU (1) AU2012306422B2 (es)
BR (1) BR112014004687A2 (es)
CA (1) CA2847514A1 (es)
CL (1) CL2014000543A1 (es)
CO (1) CO6900146A2 (es)
CR (1) CR20140113A (es)
CY (1) CY1119433T1 (es)
DK (1) DK2758401T3 (es)
DO (1) DOP2014000051A (es)
EA (1) EA025688B1 (es)
EC (1) ECSP14013231A (es)
ES (1) ES2638319T3 (es)
GT (1) GT201400043A (es)
HK (1) HK1199732A1 (es)
HR (1) HRP20171248T1 (es)
IL (1) IL231351A (es)
LT (1) LT2758401T (es)
MA (1) MA35422B1 (es)
ME (1) ME02951B (es)
MX (1) MX348064B (es)
MY (1) MY168413A (es)
PE (1) PE20141593A1 (es)
PL (1) PL2758401T3 (es)
PT (1) PT2758401T (es)
RS (1) RS56179B1 (es)
SG (1) SG11201400219PA (es)
SI (1) SI2758401T1 (es)
UA (1) UA117092C2 (es)
WO (1) WO2013034570A1 (es)
ZA (1) ZA201402498B (es)

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UA117092C2 (uk) 2011-09-06 2018-06-25 Байєр Інтеллектуал Проперті Гмбх Амінозаміщені імідазопіридазини
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EP2804864B1 (en) 2011-12-12 2017-09-06 Bayer Intellectual Property GmbH Amino-substituted imidazopyridazines
WO2013144189A1 (en) * 2012-03-29 2013-10-03 Bayer Intellectual Property Gmbh Amino-substituted imidazopyridazines
WO2013149909A1 (en) 2012-04-04 2013-10-10 Bayer Pharma Aktiengesellschaft Amino-substituted imidazopyridazines
WO2014076162A1 (en) 2012-11-19 2014-05-22 Bayer Pharma Aktiengesellschaft Aminoimidazopyridazines
WO2014110574A1 (en) 2013-01-14 2014-07-17 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
SG11201505347VA (en) 2013-01-15 2015-08-28 Incyte Corp Thiazolecarboxamides and pyridinecarboxamide compounds useful as pim kinase inhibitors
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JP2016509036A (ja) * 2013-02-20 2016-03-24 バイエル・ファルマ・アクティエンゲゼルシャフト Ｍｋｎｋ１阻害剤としての置換イミダゾ［１，２−ｂ］ピリダジン
US9556197B2 (en) 2013-08-23 2017-01-31 Incyte Corporation Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
WO2015104254A1 (en) 2014-01-09 2015-07-16 Bayer Pharma Aktiengesellschaft Amido-substituted imidazopyridazines useful in the treatment of hyper-proliferative and/or angiogenesis disorders
WO2016010897A1 (en) 2014-07-14 2016-01-21 Incyte Corporation Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
US9580418B2 (en) 2014-07-14 2017-02-28 Incyte Corporation Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
CN107108636A (zh) * 2014-12-23 2017-08-29 拜耳医药股份公司 6‑羟基苯并呋喃基‑和6‑烷氧基苯并呋喃基‑取代的咪唑并哒嗪
DK3285809T3 (da) 2015-04-20 2019-11-18 Effector Therapeutics Inc Inhibitorer af immunkontrolpunktsmodulatorer til anvendelse i behandling af kræft og infektioner.
US9540347B2 (en) 2015-05-29 2017-01-10 Incyte Corporation Pyridineamine compounds useful as Pim kinase inhibitors
AR105967A1 (es) 2015-09-09 2017-11-29 Incyte Corp Sales de un inhibidor de pim quinasa
WO2017059251A1 (en) 2015-10-02 2017-04-06 Incyte Corporation Heterocyclic compounds useful as pim kinase inhibitors
EP3397774A1 (en) 2015-12-31 2018-11-07 Effector Therapeutics Inc. Mnk biomarkers and uses thereof
WO2017157418A1 (en) 2016-03-15 2017-09-21 Bayer Pharma Aktiengesellschaft Combination of mknk1-inhibitors
WO2019113487A1 (en) 2017-12-08 2019-06-13 Incyte Corporation Low dose combination therapy for treatment of myeloproliferative neoplasms

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CN103717604B (zh) 2011-06-01 2016-06-01 拜耳知识产权有限责任公司 取代的氨基咪唑并哒嗪
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US9320737B2 (en) 2011-09-23 2016-04-26 Bayer Intellectual Property Gmbh Substituted imidazopyridazines
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EP2804864B1 (en) 2011-12-12 2017-09-06 Bayer Intellectual Property GmbH Amino-substituted imidazopyridazines
WO2013144189A1 (en) 2012-03-29 2013-10-03 Bayer Intellectual Property Gmbh Amino-substituted imidazopyridazines
WO2013149909A1 (en) 2012-04-04 2013-10-10 Bayer Pharma Aktiengesellschaft Amino-substituted imidazopyridazines
WO2014076162A1 (en) 2012-11-19 2014-05-22 Bayer Pharma Aktiengesellschaft Aminoimidazopyridazines
EP2951181A1 (en) 2013-01-30 2015-12-09 Bayer Pharma Aktiengesellschaft Amidoimidazopyridazines as mknk-1 kinase inhibitors
JP2016509036A (ja) 2013-02-20 2016-03-24 バイエル・ファルマ・アクティエンゲゼルシャフト Ｍｋｎｋ１阻害剤としての置換イミダゾ［１，２−ｂ］ピリダジン
WO2015104254A1 (en) 2014-01-09 2015-07-16 Bayer Pharma Aktiengesellschaft Amido-substituted imidazopyridazines useful in the treatment of hyper-proliferative and/or angiogenesis disorders

Also Published As

Publication number Publication date
MA35422B1 (fr) 2014-09-01
JP6174583B2 (ja) 2017-08-02
EA025688B1 (ru) 2017-01-30
GT201400043A (es) 2015-04-06
PE20141593A1 (es) 2014-11-12
JP2014525469A (ja) 2014-09-29
CL2014000543A1 (es) 2014-09-26
SG11201400219PA (en) 2014-03-28
NZ622129A (en) 2016-06-24
US9499547B2 (en) 2016-11-22
ECSP14013231A (es) 2014-04-30
UA117092C2 (uk) 2018-06-25
US20140296231A1 (en) 2014-10-02
MY168413A (en) 2018-11-09
EA201400311A1 (ru) 2014-09-30
CN103958515B (zh) 2016-11-09
RS56179B1 (sr) 2017-11-30
PT2758401T (pt) 2017-08-30
DK2758401T3 (en) 2017-09-11
ES2638319T3 (es) 2017-10-19
BR112014004687A2 (pt) 2017-03-28
ZA201402498B (en) 2017-09-27
SI2758401T1 (sl) 2017-10-30
PL2758401T3 (pl) 2017-11-30
ME02951B (me) 2018-07-20
AU2012306422B2 (en) 2017-10-26
AP2014007496A0 (en) 2014-03-31
CN103958515A (zh) 2014-07-30
AP3853A (es) 2016-09-30
DOP2014000051A (es) 2014-06-01
AU2012306422A1 (en) 2014-03-27
MX2014002697A (es) 2014-04-25
CA2847514A1 (en) 2013-03-14
IL231351A (en) 2017-01-31
CY1119433T1 (el) 2018-03-07
LT2758401T (lt) 2017-08-25
EP2758401A1 (en) 2014-07-30
HK1199732A1 (en) 2015-07-17
EP2758401B1 (en) 2017-05-31
KR20140059268A (ko) 2014-05-15
MX348064B (es) 2017-05-26
WO2013034570A1 (en) 2013-03-14
CR20140113A (es) 2014-05-02
IL231351A0 (en) 2014-04-30
HRP20171248T1 (hr) 2017-10-20

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