CO6741144A2 - Indicador vaginal para detectar biomarcadores de una buena salud - Google Patents

Indicador vaginal para detectar biomarcadores de una buena salud

Info

Publication number
CO6741144A2
CO6741144A2 CO13124838A CO13124838A CO6741144A2 CO 6741144 A2 CO6741144 A2 CO 6741144A2 CO 13124838 A CO13124838 A CO 13124838A CO 13124838 A CO13124838 A CO 13124838A CO 6741144 A2 CO6741144 A2 CO 6741144A2
Authority
CO
Colombia
Prior art keywords
hydrogen peroxide
detection signal
lactic acid
amount
determinable
Prior art date
Application number
CO13124838A
Other languages
English (en)
Inventor
Stephanie M Martin
Ronnie L Phillips
Sangwook Lee
Junmo Gil
Original Assignee
Kimberly Clark Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Co filed Critical Kimberly Clark Co
Publication of CO6741144A2 publication Critical patent/CO6741144A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4318—Evaluation of the lower reproductive system
    • A61B5/4337—Evaluation of the lower reproductive system of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0295—Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/20—Tampons, e.g. catamenial tampons; Accessories therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90209—Oxidoreductases (1.) acting on NADH or NADPH (1.6), e.g. those with a heme protein as acceptor (1.6.2) (general), Cytochrome-b5 reductase (1.6.2.2) or NADPH-cytochrome P450 reductase (1.6.2.4)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90212—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/90241—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Optics & Photonics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

De acuerdo con una incorporación de la presente invención, se describe un kit de diagnóstico para biomarcadores de salud vaginal benéfica. El kit incluye una primera zona de detección dentro de la cual una señal de detección de ácido D- láctico es capaz de ser generada, en donde la presencia o cantidad de ácido D- láctico es determinable a partir de la señal de detección de ácido D-láctico. El kit además incluye una segunda zona de detección dentro de la cual una señal de peróxido de hidrógeno es capaz de ser generada, en donde la presencia o cantidad de peróxido de hidrógeno es determinable a partir de la señal de detección de peróxido de hidrógeno.En aún otra incorporación de la presente revelación, se describe un método para detectar biomarcadores de salud vaginal benéfica. El método incluye poner en contacto una muestra de prueba con un kit de prueba que comprende una primera zona de detección dentro de la cual una señal de detección de ácido D- láctico es capaz de ser generada. La presencia o cantidad de ácido D- láctico es determinable a partir de la señal de detección de ácido D-láctico. El kit de prueba además comprende una segunda zona de detección dentro de la cual una señal de peróxido de hidrógeno es capaz de ser generada, en donde la presencia o cantidad de peróxido de hidrógeno es determinable a partir de la señal de detección de peróxido de hidrógeno. El método además incluye detectar la presencia o cantidad de ácido D-láctico a partir de la señal de detección de ácido D-láctico y determinar la presencia o cantidad de peróxido de hidrógeno a partir de la señal de detección de peróxido de hidrógeno.
CO13124838A 2010-11-22 2013-05-21 Indicador vaginal para detectar biomarcadores de una buena salud CO6741144A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/951,652 US9034593B2 (en) 2010-11-22 2010-11-22 Vaginal indicator to detect biomarkers of good health

Publications (1)

Publication Number Publication Date
CO6741144A2 true CO6741144A2 (es) 2013-08-30

Family

ID=46064974

Family Applications (1)

Application Number Title Priority Date Filing Date
CO13124838A CO6741144A2 (es) 2010-11-22 2013-05-21 Indicador vaginal para detectar biomarcadores de una buena salud

Country Status (14)

Country Link
US (1) US9034593B2 (es)
EP (1) EP2643473A2 (es)
JP (1) JP2014501502A (es)
KR (1) KR101821002B1 (es)
CN (1) CN103403179A (es)
AR (1) AR083949A1 (es)
AU (1) AU2011333420B2 (es)
BR (1) BR112013012460B1 (es)
CO (1) CO6741144A2 (es)
IL (1) IL225875A0 (es)
MX (1) MX340725B (es)
RU (1) RU2013126248A (es)
SG (1) SG189968A1 (es)
WO (1) WO2012069941A2 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9110053B2 (en) * 2010-08-20 2015-08-18 Agilent Technologies, Inc. Dried blood spotting paper device and method
US9034593B2 (en) 2010-11-22 2015-05-19 Kimberly-Clark Worldwide, Inc. Vaginal indicator to detect biomarkers of good health
US9907707B2 (en) 2011-06-03 2018-03-06 The Procter & Gamble Company Sensor systems comprising auxiliary articles
IL214096A (en) * 2011-07-14 2016-02-29 Gideon Mor A system for detecting meconium in amniotic fluid
US20130164830A1 (en) * 2011-12-21 2013-06-27 Kimberly-Clark Worldwide, Inc. Combination Assay Device and Method for Detecting Compounds in Vaginal Fluid
WO2015021243A1 (en) 2013-08-08 2015-02-12 The Procter & Gamble Company Sensor systems for absorbent articles comprising sensor gates
KR101463005B1 (ko) * 2013-10-15 2014-11-18 (주)한국해양기상기술 특정 파장에 대한 형광 특성을 갖는 미생물 검사방법
JP5751365B1 (ja) * 2014-03-28 2015-07-22 栗田工業株式会社 塩素濃度測定用組成物
WO2016028497A1 (en) * 2014-08-21 2016-02-25 Naseri, Sara System and method for non-invasive analysis of bodily fluids
CN104388530B (zh) * 2014-11-28 2016-09-14 孟怡然 一种稳定性强的乳酸检测试剂
CN104745544B (zh) * 2015-03-26 2017-10-27 山东大学 一种d‑乳酸氧化酶及其在d‑乳酸检测中的应用
US10285871B2 (en) 2016-03-03 2019-05-14 The Procter & Gamble Company Absorbent article with sensor
EP3429477A4 (en) 2016-03-18 2019-03-06 Qurasense, Inc. COLLECTION DEVICE FOR THE DIAGNOSIS OF VAGINAL OUTLET
RU2649146C1 (ru) * 2017-08-10 2018-03-30 ФЕДЕРАЛЬНОЕ ГОСУДАРСТВЕННОЕ БЮДЖЕТНОЕ УЧРЕЖДЕНИЕ НАУКИ ИНСТИТУТ ОРГАНИЧЕСКОЙ ХИМИИ им. Н.Д. ЗЕЛИНСКОГО РОССИЙСКОЙ АКАДЕМИИ НАУК (ИОХ РАН) Способ получения ацилоксизамещенных барбитуровых кислот
EP3787583A1 (en) 2018-05-04 2021-03-10 The Procter & Gamble Company Sensor devices and systems for monitoring the basic needs of an infant
US11051996B2 (en) 2018-08-27 2021-07-06 The Procter & Gamble Company Sensor devices and systems for monitoring the basic needs of an infant
WO2021167011A1 (ja) * 2020-02-21 2021-08-26 キッコーマン株式会社 検体の状態を評価するためのデバイス、それを含むシステム、検体の状態を評価する方法及びそれに用いる乳酸デヒドロゲナーゼ
CN112730401B (zh) * 2021-01-05 2022-07-12 苏州大学 可穿戴阴道分泌物监测传感器及女性用品

Family Cites Families (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2981606A (en) 1955-06-20 1961-04-25 Lilly Co Eli Glucose indicator and method
US2912309A (en) 1956-02-06 1959-11-10 Miles Lab Indicator for detecting glucose
US3092465A (en) 1960-03-25 1963-06-04 Miles Lab Diagnostic test device for blood sugar
GB960167A (en) 1970-03-20 1964-06-10 Miles Lab Improvements in or relating to diagnostic compositions
NL134608C (es) 1963-06-17
DE1598133B2 (de) 1966-09-01 1974-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und diagnostisches Mittel zur Bestimmung von Hydroperoxiden bzw. peroxidatisch wirksamen Substanzen
CH522222A (de) 1967-03-10 1972-06-15 Merck Patent Gmbh Verfahren zur Bestimmung von Wasserstoffperoxid und Mittel zur Durchführung des Verfahrens
US3630847A (en) 1967-07-20 1971-12-28 Boehringer Mannheim Gmbh Diagnostic agent for use in the determination of hydroperoxides and of peroxidate-active substances
US3509872A (en) 1967-11-30 1970-05-05 Andrew Truhan Body fluid test stick
US3627697A (en) 1969-04-09 1971-12-14 Boehringer Mannheim Gmbh Hydroperoxide diagnostic agents containing a chromogen indicator
US3654179A (en) 1971-03-01 1972-04-04 Miles Lab Indicator for detecting hydrogen peroxide and peroxidative compounds containing bindschedler's green
US3654180A (en) 1971-03-01 1972-04-04 Miles Lab Indicator for detecting hydrogen peroxide and peroxidative compounds containing alpha naphthoflavone
US3853470A (en) 1972-08-30 1974-12-10 Medico Electronic Inc Reagent and method for glucose determination
US4089747A (en) 1976-08-09 1978-05-16 Eastman Kodak Company Compositions for the detection of hydrogen peroxide
USRE32016E (en) 1976-12-10 1985-10-29 Eastman Kodak Company Analysis of lactic acid or lactate using lactate oxidase
US4166763A (en) 1976-12-10 1979-09-04 Eastman Kodak Company Analysis of lactic acid or lactate using lactate oxidase
GB8505899D0 (en) 1985-03-07 1985-04-11 Boots Celltech Diagnostics Assay reagents
IL84443A (en) 1987-11-11 1993-01-14 Schoenfeld A Vaginal tampon
US5126247A (en) 1988-02-26 1992-06-30 Enzymatics, Inc. Method, system and devices for the assay and detection of biochemical molecules
US5075077A (en) 1988-08-02 1991-12-24 Abbott Laboratories Test card for performing assays
IT215747Z2 (it) 1989-03-07 1990-11-05 Prospero Nucci Sonda monouso per la determinazione del ph vaginale e di altri indici.
US5510244A (en) * 1992-01-30 1996-04-23 Kanzaki Paper Manufacturing Co., Ltd. Apparatus and method for assaying optical isomers
US5360595A (en) 1993-08-19 1994-11-01 Miles Inc. Preparation of diagnostic test strips containing tetrazolium salt indicators
US5425377A (en) 1994-08-25 1995-06-20 Caillouette; James C. pH measurement of body fluid
JP2000512267A (ja) 1996-05-09 2000-09-19 ノボ ノルディスク アクティーゼルスカブ 抗微生物ペルオキシダーゼ組成物
US5823953A (en) 1996-06-20 1998-10-20 Roskin; Amy C. Secretion analysis apparatus and method
US5792618A (en) 1996-09-27 1998-08-11 Moss, Inc. Liquid single-component substrates for detection or assay of horseradish peroxidase
US6093394A (en) 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
US6479015B1 (en) * 1998-03-03 2002-11-12 Pepex Biomedical, Llc Apparatus for monitoring a level of a chemical species in a body fluid
JP2927772B2 (ja) 1998-03-09 1999-07-28 株式会社大貴 紙おむつ
US6472163B1 (en) 1998-04-20 2002-10-29 Kairos Scientific, Inc. Solid phase enzyme kinetics screening in microcolonies
US6656697B1 (en) 1998-09-28 2003-12-02 Lifescan, Inc. Diagnostics based on tetrazolium compounds
GB9906140D0 (en) 1999-03-17 1999-05-12 Univ Bristol A diagnostic test
AU4665900A (en) 1999-04-26 2000-11-10 Procter & Gamble Company, The A blood detection composition
US6562297B1 (en) 1999-08-12 2003-05-13 Common Sense Ltd. pH sensor for indicating the pH of a sample
US6426227B1 (en) 1999-08-31 2002-07-30 Common Sense Ltd. Method for analyzing secreted bodily fluids
SE521022C2 (sv) 2001-09-20 2003-09-23 Ellen Ab Mjölksyraproducerande bakterier för användning som probiotiska organismer i vaginan hos människa
US8097433B2 (en) 2005-11-22 2012-01-17 Common Sense, Ltd. Diagnostic composition and article for monitoring intravaginal infections
US6921647B2 (en) 2001-07-19 2005-07-26 Common Sense Ltd. Secretion-monitoring article
US20070134740A1 (en) 2005-12-12 2007-06-14 David Brusilovsky Compositions and articles for detection of analytes exceeding a pre-set threshold
US6627394B2 (en) 2001-07-19 2003-09-30 Common Sense Ltd. Diagnostic pad
US7314752B2 (en) 2001-07-19 2008-01-01 Common Sense, Ltd. Secretion-monitoring article
US6719691B2 (en) 2001-07-26 2004-04-13 Common Sense Ltd. Method, device and kit for obtaining biological samples
GB0120062D0 (en) 2001-08-17 2001-10-10 Osmetech Plc Detection of bacterial vaginosis
US6723500B2 (en) * 2001-12-05 2004-04-20 Lifescan, Inc. Test strips having reaction zones and channels defined by a thermally transferred hydrophobic barrier
ITTO20030404A1 (it) 2003-05-30 2004-11-30 Rottapharm S R L Composizione per il ripristino dell'ecosistema vaginale
US7592020B2 (en) * 2003-12-05 2009-09-22 Kimberly-Clark Worldwide, Inc. Personal care products with visual indicator of vaginitis
US7282349B2 (en) 2003-12-16 2007-10-16 Kimberly-Clark Worldwide, Inc. Solvatochromatic bacterial detection
US7399608B2 (en) 2003-12-16 2008-07-15 Kimberly-Clark Worldwide, Inc. Microbial detection and quantification
US20050131287A1 (en) * 2003-12-16 2005-06-16 Kimberly-Clark Worldwide, Inc. Detection of premature rupture of the amniotic membrane
US20050191704A1 (en) 2004-03-01 2005-09-01 Kimberly-Clark Worldwide, Inc. Assay devices utilizing chemichromic dyes
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US20070128589A1 (en) * 2005-07-13 2007-06-07 Sanders Mitchell C Substrates, sensors, and methods for assessing conditions in females
CN1850985A (zh) * 2006-03-07 2006-10-25 北京中生金域诊断技术有限公司 细菌性阴道病联合测定试剂盒
SI22285A (sl) 2006-06-05 2007-12-31 Zemljič Lidija Fras Tampon, ki vsebuje pH regulirajočo ter antibakterijsko in antimikotično aktivno formulacijo, in postopek njegove izdelave
US7591978B2 (en) 2006-08-10 2009-09-22 Inverness Medical Switzerland Gmbh Solid phase test device for sialidase assay
US20080057528A1 (en) 2006-08-30 2008-03-06 Kimberly-Clark Worldwide, Inc. Detection of hydrogen peroxide released by enzyme-catalyzed oxidation of an analyte
US7531319B2 (en) 2006-08-31 2009-05-12 Kimberly-Clark Worldwide, Inc. Array for rapid detection of a microorganism
CN101594888A (zh) 2006-12-15 2009-12-02 欧兰益生公司 含有产乳酸细菌的吸收制品
CN101324559A (zh) * 2007-06-13 2008-12-17 苏州艾杰生物科技有限公司 D-乳酸诊断/测定试剂盒及d-乳酸浓度测定方法
WO2009139811A2 (en) 2008-05-15 2009-11-19 Tianxin Wang Chemiluminescent methods and reagents for analyte detection
WO2010017192A1 (en) 2008-08-05 2010-02-11 Ph Diagnostics Inc. Apparatus, method and system for determining a physiological condition within a mammal
US20120040387A1 (en) 2009-01-19 2012-02-16 Asahi Kasei Pharma Corporation Method and reagent for measuring mevalonic acid, 3-hydroxymethylglutaryl coenzyme a, and coenzyme a
US20100193386A1 (en) 2009-01-30 2010-08-05 Adrienne Rae Loyd Vaginal-Health Products Comprising Colored Applicators
CN101487041A (zh) 2009-02-26 2009-07-22 广州鸿琪光学仪器科技有限公司 细菌性阴道病联合检测试剂
US9034593B2 (en) 2010-11-22 2015-05-19 Kimberly-Clark Worldwide, Inc. Vaginal indicator to detect biomarkers of good health

Also Published As

Publication number Publication date
US9034593B2 (en) 2015-05-19
AU2011333420B2 (en) 2015-04-30
AU2011333420A1 (en) 2013-05-09
KR101821002B1 (ko) 2018-01-23
WO2012069941A2 (en) 2012-05-31
RU2013126248A (ru) 2014-12-27
KR20140029362A (ko) 2014-03-10
US20120130195A1 (en) 2012-05-24
BR112013012460B1 (pt) 2019-10-08
SG189968A1 (en) 2013-06-28
WO2012069941A3 (en) 2012-08-23
IL225875A0 (en) 2013-06-27
JP2014501502A (ja) 2014-01-23
MX340725B (es) 2016-07-21
EP2643473A2 (en) 2013-10-02
AR083949A1 (es) 2013-04-10
MX2013005740A (es) 2013-08-01
BR112013012460A2 (pt) 2016-08-30
CN103403179A (zh) 2013-11-20

Similar Documents

Publication Publication Date Title
CO6741144A2 (es) Indicador vaginal para detectar biomarcadores de una buena salud
NZ705411A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
MX350533B (es) Biomarcadores de cancer pancreatico y usos de los mismos.
NZ608384A (en) Biomarkers of renal injury
WO2010013138A3 (en) Methods and compositions for detection of a pathogen, disease, medical condition, or biomarker thereof
NZ605698A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1248311B (zh) 預測死亡率及檢測重症疾病
NZ628843A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
AU2007225434A8 (en) Method of detecting or diagnosing of a neurodegenerative disease or condition
TR201904386T4 (tr) Nükleotidleri içeren nükleozomların saptanmasına yönelik yöntem.
EP4235181A3 (en) Biomarker detection process and assay of neurological condition
WO2010120917A3 (en) Expanding the dynamic range of a test strip
NZ624614A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010057184A3 (en) Methods for detection of acute kidney injury in humans
IN2014CN01787A (es)
WO2010005991A3 (en) Circulating tumor and tumor stem cell detection using genomic specific probes
DE602007013524D1 (de) Erkennung und vorhersage von frühgeburten
PE20141450A1 (es) Ensayo de lisiloxidasa-homologo 2 y metodos de uso del mismo
CO6311041A2 (es) Un metodo para determinar y monitorear un cancer ginecologico que comprende la determinacion de niveles de biomarcadores en una muestra biologica
ATE533855T1 (de) Testverfahren zum nachweis lebensfähiger mikrobenzellen in einer probe
NZ628085A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ608316A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ606124A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
NZ598741A (en) Methods and composition for diagnosis and prognosis of renal injury and renal failure by performing assays to detect metalloproteinase inhibitor 4 on a body fluid sample
EP2585832A4 (en) REDUCTION OF INCORRECT RESULTS OF TEST MEASUREMENTS

Legal Events

Date Code Title Description
FA Application withdrawn