CO6660508A2 - Sistema polimérico para suministrar una solución no viscosa a base de prostaglandina, sin conservadores - Google Patents
Sistema polimérico para suministrar una solución no viscosa a base de prostaglandina, sin conservadoresInfo
- Publication number
- CO6660508A2 CO6660508A2 CO12234226A CO12234226A CO6660508A2 CO 6660508 A2 CO6660508 A2 CO 6660508A2 CO 12234226 A CO12234226 A CO 12234226A CO 12234226 A CO12234226 A CO 12234226A CO 6660508 A2 CO6660508 A2 CO 6660508A2
- Authority
- CO
- Colombia
- Prior art keywords
- prostaglandin
- solution
- preservatives
- solution based
- viscous solution
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La invención se refiere a una solución oftálmica, cuyo ingrediente activo incluye por lo menos una prostaglandina; dicha solución no contiene agentes antimicrobianos, notablemente del tipo de amonio cuaternario (tales como cloruro de benzalconio [BAK]). Esta invención también se refiere a un sistema polimérico de suministro, que ha sido desarrollado para permitir que la solución de prostaglandina sea tan efectiva como una solución que contiene BAK, pero sin sus desventajas, desde el punto de vista toxicológico y alergénico.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35969910P | 2010-06-29 | 2010-06-29 | |
FR1055236A FR2961694B1 (fr) | 2010-06-29 | 2010-06-29 | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6660508A2 true CO6660508A2 (es) | 2013-04-30 |
Family
ID=43064334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO12234226A CO6660508A2 (es) | 2010-06-29 | 2012-12-27 | Sistema polimérico para suministrar una solución no viscosa a base de prostaglandina, sin conservadores |
Country Status (27)
Country | Link |
---|---|
US (2) | US20110319487A1 (es) |
EP (1) | EP2588078B1 (es) |
JP (2) | JP5657789B2 (es) |
KR (1) | KR101809713B1 (es) |
CN (2) | CN102958509B (es) |
AU (1) | AU2011273549B2 (es) |
BR (1) | BR112012033435B1 (es) |
CA (1) | CA2802816C (es) |
CL (1) | CL2012003684A1 (es) |
CO (1) | CO6660508A2 (es) |
DK (1) | DK2588078T3 (es) |
EA (1) | EA025026B1 (es) |
ES (1) | ES2486793T3 (es) |
FR (1) | FR2961694B1 (es) |
HK (2) | HK1178446A1 (es) |
HR (1) | HRP20140631T1 (es) |
MA (1) | MA34324B1 (es) |
MX (1) | MX2012014503A (es) |
PL (1) | PL2588078T3 (es) |
PT (1) | PT2588078E (es) |
RS (1) | RS53417B (es) |
SG (1) | SG186361A1 (es) |
SI (1) | SI2588078T1 (es) |
SM (1) | SMT201400098B (es) |
TN (1) | TN2012000588A1 (es) |
UA (1) | UA107718C2 (es) |
WO (1) | WO2012001009A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012525386A (ja) | 2009-05-01 | 2012-10-22 | アエリエ・ファーマシューティカルズ・インコーポレーテッド | 疾患の治療のための二重機構阻害剤 |
FR2961694B1 (fr) | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
US9278132B2 (en) | 2012-02-13 | 2016-03-08 | Bausch & Lomb Incorporated | Ophthalmic pharmaceutical compositions and methods of making and using same |
US10113033B2 (en) | 2013-03-08 | 2018-10-30 | Polyactiva Pty Ltd | Polymer conjugate for delivery of a bioactive agent |
CN105358146B (zh) | 2013-03-08 | 2019-11-29 | 波利艾克蒂瓦有限公司 | 用于递送生物活性剂的聚合物缀合物 |
CN104288092A (zh) * | 2013-07-16 | 2015-01-21 | 广东东阳光药业有限公司 | 拉坦前列素滴眼剂 |
US9115109B2 (en) * | 2013-08-15 | 2015-08-25 | Chirogate International Inc. | Processes and intermediates for the preparations of isomer free prostaglandins |
EP3057575B1 (en) * | 2013-10-15 | 2021-09-08 | Pharmathen S.A. | Preservative free pharmaceutical compositions for ophthalmic administration |
GR1008330B (el) * | 2013-10-17 | 2014-10-20 | "Φαρματεν Α.Β.Ε.Ε.", | Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση εχoν βελτιωμενες φυσικες ιδιοτητες και ογκο σταγονας |
GR1008483B (el) * | 2013-12-23 | 2015-05-12 | Rafarm Α.Ε.Β.Ε., | Οφθαλμικη φαρμακευτικη συνθεση και μεθοδος για την παρασκευη αυτης |
CN105012231A (zh) * | 2014-04-30 | 2015-11-04 | 四川科伦药物研究院有限公司 | 一种包含PGF2α衍生物的稳定性良好的眼用制剂及其制备方法 |
ES2584534B1 (es) * | 2015-03-27 | 2017-03-13 | Retinset, S.L. | Formulación tópica oftálmica de bosentan |
ES2747302T3 (es) | 2015-06-09 | 2020-03-10 | Medproject Pharma Entw Und Vertriebsgesellschaft Mbh | Gel oftálmico de bimatoprost aplicable en gotas |
GR1009040B (el) * | 2016-04-19 | 2017-05-19 | Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων | Φαρμακευτικο οφθαλμικο σκευασμα ελευθερο συντηρητικου |
WO2018033854A1 (en) * | 2016-08-15 | 2018-02-22 | Santen Pharmaceutical Co., Ltd. | Ophthalmic composition and a method for treating ocular hypertension and glaucoma |
KR102568082B1 (ko) | 2016-08-31 | 2023-08-17 | 에어리 파마슈티컬즈, 인코포레이티드 | 안과용 조성물 |
IT201600103956A1 (it) * | 2016-10-17 | 2018-04-17 | Omikron Italia S R L | Formulazione oftalmica comprendente citicolina veicolata da liposomi per il trattamento del glaucoma |
KR101770324B1 (ko) * | 2016-11-09 | 2017-08-22 | 주식회사태준제약 | 안압 강하용 점안 조성물 |
IL269321B (en) | 2017-03-14 | 2022-07-01 | Polyactiva Pty Ltd | Drug-polymer conjugation that includes a prostaglandin analog conjugated to a polytriazole polymer |
US11696955B2 (en) | 2017-03-14 | 2023-07-11 | Polyactiva Pty Ltd | Drug-polymer conjugate |
US11207417B2 (en) | 2017-03-14 | 2021-12-28 | Polyactiva Pty Ltd | Drug-polymer conjugate |
AU2018243687C1 (en) | 2017-03-31 | 2020-12-24 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
JP6931493B2 (ja) | 2017-06-22 | 2021-09-08 | ヨンスン ファイン ケミカル カンパニー,リミテッド | 緑内障治療用点眼組成物 |
CN110237031B (zh) | 2018-07-12 | 2022-02-11 | 尼科斯股份有限公司 | 包含释放一氧化氮的前列酰胺的眼用组合物 |
WO2020028055A1 (en) * | 2018-07-31 | 2020-02-06 | ADLER, Benjamin, Aaron | Ophthalmic formulations and uses thereof |
US11427563B2 (en) | 2018-09-14 | 2022-08-30 | Aerie Pharmaceuticals, Inc. | Aryl cyclopropyl-amino-isoquinolinyl amide compounds |
CN110711175A (zh) * | 2019-11-12 | 2020-01-21 | 南京华盖制药有限公司 | 一种他氟前列素滴眼剂及其制备方法 |
US20230263727A1 (en) * | 2022-01-14 | 2023-08-24 | Somerset Therapeutics, Llc | Ophthalmologically suitable low pka buffer-containing pilocarpine compositions and related methods |
US11969410B2 (en) | 2022-02-09 | 2024-04-30 | Somerset Therapeutics, Llc | Low pH pilocarpine and brimonidine compound formulations and related methods |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10021A (en) * | 1853-09-13 | Screw-eastemtito- for boots and shoes | ||
IL80298A (en) | 1986-10-14 | 1993-01-31 | Res & Dev Co Ltd | Eye drops |
US5631287A (en) | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
US6646001B2 (en) * | 1997-12-19 | 2003-11-11 | Alcon Manufacturing, Ltd. | Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension |
DK1098649T3 (da) * | 1998-04-02 | 2004-10-04 | Novartis Ag | Fremgangsmåde til stabilisering af farmaceutiske sammensætninger med speciel anvendelse af antioxidant |
US20030018079A1 (en) * | 2000-11-13 | 2003-01-23 | Richardson Helene | Treatment |
US7074827B2 (en) * | 2002-10-24 | 2006-07-11 | Sucampo Ag (Usa) Inc. | Method for treating ocular hypertension and glaucoma |
FR2918891B1 (fr) | 2007-07-20 | 2009-09-25 | Thea Sa Lab | Solution ophtalmique a base de prostaglandines sans conservateur |
AU2008310956B2 (en) * | 2007-10-08 | 2014-08-07 | Aurinia Pharmaceuticals Inc. | Ophthalmic compositions comprising calcineurin inhibitors or mTOR inhibitors |
WO2009084021A2 (en) * | 2007-10-16 | 2009-07-09 | Sun Pharma Advanced Research Company Limited | Novel ophthalmic compositions |
EP2127638A1 (en) * | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
FR2961694B1 (fr) * | 2010-06-29 | 2013-01-25 | Thea Lab | Systeme de delivrance polymerique d'une solution non visqueuse a base de prostaglandine sans conservateur |
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2010
- 2010-06-29 FR FR1055236A patent/FR2961694B1/fr active Active
-
2011
- 2011-06-28 MA MA35472A patent/MA34324B1/fr unknown
- 2011-06-28 KR KR1020127033996A patent/KR101809713B1/ko active IP Right Grant
- 2011-06-28 SI SI201130234T patent/SI2588078T1/sl unknown
- 2011-06-28 SG SG2012092284A patent/SG186361A1/en unknown
- 2011-06-28 PL PL11727707T patent/PL2588078T3/pl unknown
- 2011-06-28 EP EP11727707.9A patent/EP2588078B1/fr active Active
- 2011-06-28 CN CN201180032001.9A patent/CN102958509B/zh active Active
- 2011-06-28 BR BR112012033435-2A patent/BR112012033435B1/pt active IP Right Grant
- 2011-06-28 WO PCT/EP2011/060848 patent/WO2012001009A1/fr active Application Filing
- 2011-06-28 EA EA201291307A patent/EA025026B1/ru not_active IP Right Cessation
- 2011-06-28 JP JP2013517254A patent/JP5657789B2/ja active Active
- 2011-06-28 RS RS20140353A patent/RS53417B/en unknown
- 2011-06-28 UA UAA201301063A patent/UA107718C2/ru unknown
- 2011-06-28 PT PT117277079T patent/PT2588078E/pt unknown
- 2011-06-28 US US13/170,716 patent/US20110319487A1/en not_active Abandoned
- 2011-06-28 MX MX2012014503A patent/MX2012014503A/es active IP Right Grant
- 2011-06-28 DK DK11727707.9T patent/DK2588078T3/da active
- 2011-06-28 CN CN201410538280.1A patent/CN104274396B/zh active Active
- 2011-06-28 ES ES11727707.9T patent/ES2486793T3/es active Active
- 2011-06-28 CA CA2802816A patent/CA2802816C/fr active Active
- 2011-06-28 AU AU2011273549A patent/AU2011273549B2/en active Active
-
2012
- 2012-08-27 US US13/595,165 patent/US8637054B2/en active Active
- 2012-12-12 TN TNP2012000588A patent/TN2012000588A1/fr unknown
- 2012-12-26 CL CL2012003684A patent/CL2012003684A1/es unknown
- 2012-12-27 CO CO12234226A patent/CO6660508A2/es not_active Application Discontinuation
-
2013
- 2013-05-06 HK HK13105429.5A patent/HK1178446A1/xx unknown
-
2014
- 2014-07-02 HR HRP20140631AT patent/HRP20140631T1/hr unknown
- 2014-07-23 SM SM201400098T patent/SMT201400098B/xx unknown
- 2014-09-19 JP JP2014191849A patent/JP5877885B2/ja active Active
-
2015
- 2015-02-27 HK HK15102052.4A patent/HK1201464A1/xx unknown
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Legal Events
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FC | Application refused |