CO6341569A2 - Vacuna de vesicula de membrana externa nativa multivalente del meningococo, metodo para su fabricacion y uso. - Google Patents
Vacuna de vesicula de membrana externa nativa multivalente del meningococo, metodo para su fabricacion y uso.Info
- Publication number
- CO6341569A2 CO6341569A2 CO10164103A CO10164103A CO6341569A2 CO 6341569 A2 CO6341569 A2 CO 6341569A2 CO 10164103 A CO10164103 A CO 10164103A CO 10164103 A CO10164103 A CO 10164103A CO 6341569 A2 CO6341569 A2 CO 6341569A2
- Authority
- CO
- Colombia
- Prior art keywords
- vaccine
- multivally
- meningococo
- vesicula
- manufacturing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/36—Adaptation or attenuation of cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5746208P | 2008-05-30 | 2008-05-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6341569A2 true CO6341569A2 (es) | 2011-11-21 |
Family
ID=41444870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO10164103A CO6341569A2 (es) | 2008-05-30 | 2010-12-29 | Vacuna de vesicula de membrana externa nativa multivalente del meningococo, metodo para su fabricacion y uso. |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US9387239B2 (enExample) |
| EP (1) | EP2296699A4 (enExample) |
| JP (2) | JP5723768B2 (enExample) |
| KR (1) | KR20110053314A (enExample) |
| CN (1) | CN102105166A (enExample) |
| AU (1) | AU2009262893B2 (enExample) |
| BR (1) | BRPI0913268A2 (enExample) |
| CA (1) | CA2726465A1 (enExample) |
| CO (1) | CO6341569A2 (enExample) |
| CR (1) | CR11812A (enExample) |
| DO (1) | DOP2010000364A (enExample) |
| EC (1) | ECSP10010723A (enExample) |
| IL (1) | IL209660A0 (enExample) |
| MX (1) | MX2010012999A (enExample) |
| NZ (1) | NZ589812A (enExample) |
| RU (1) | RU2477145C2 (enExample) |
| UA (1) | UA99659C2 (enExample) |
| WO (1) | WO2009158142A1 (enExample) |
| ZA (1) | ZA201008548B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1179072A2 (en) | 1999-05-19 | 2002-02-13 | Chiron S.P.A. | Combination neisserial compositions |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| EP2544714A1 (en) * | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Vaccine composition |
| CA2808975C (en) * | 2010-08-23 | 2018-10-30 | Wyeth Llc | Stable formulations of neisseria meningitidis rlp2086 antigens |
| GB201015132D0 (en) * | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| CA2810971C (en) * | 2010-09-10 | 2020-11-03 | Novartis Ag | Developments in meningococcal outer membrane vesicles |
| KR101584871B1 (ko) | 2010-09-10 | 2016-01-22 | 와이어쓰 엘엘씨 | 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체 |
| CA2846290A1 (en) * | 2011-08-31 | 2013-03-07 | Children's Hospital & Research Center Oakland | Engineered sequences to facilitate expression of antigens in neisseria and methods of use |
| MX2014008988A (es) | 2012-02-02 | 2014-08-27 | Novartis Ag | Promotores para aumento de expresion de proteinas en meningococo. |
| WO2013132040A2 (en) * | 2012-03-08 | 2013-09-12 | Novartis Ag | In vitro potency assay for protein-based meningococcal vaccines |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| KR101452830B1 (ko) * | 2012-04-06 | 2014-10-21 | 아이진 주식회사 | 두 가지 항암물질을 동시에 제공하는 대장균 균주 |
| AU2013320313B2 (en) | 2012-09-18 | 2018-07-12 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
| CA2903716C (en) | 2013-03-08 | 2019-04-09 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| KR20190049940A (ko) | 2015-02-19 | 2019-05-09 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| WO2017129761A1 (en) * | 2016-01-28 | 2017-08-03 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport | Modified hexa-acylated neisserial lps |
| EP3263695A1 (en) * | 2016-06-29 | 2018-01-03 | GlaxoSmithKline Biologicals SA | Immunogenic compositions |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| HUE052751T2 (hu) * | 2016-11-25 | 2021-05-28 | Glaxosmithkline Biologicals Sa | Natív OMV-antigén konjugátumok és alkalmazásuk |
| SG11201906519RA (en) | 2017-01-31 | 2019-08-27 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| CN107961369B (zh) * | 2017-03-22 | 2020-08-11 | 武汉博沃生物科技有限公司 | 多价脑膜炎球菌缀合疫苗及其制备方法 |
| WO2020191361A2 (en) | 2019-03-21 | 2020-09-24 | Codiak Biosciences, Inc. | Extracellular vesicles for vaccine delivery |
| CA3155669A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CN113151354B (zh) * | 2021-03-22 | 2022-03-08 | 中国农业科学院兰州兽医研究所 | 一种用于条件性敲除目的基因的载体及条件性敲除目的基因的方法 |
| IT202400003229A1 (it) | 2024-02-15 | 2025-08-15 | Cioccio Vito Di | Procedimento per la purificazione di omv da batteri gram-negativi, e relativi usi |
| CN119020251A (zh) * | 2024-08-26 | 2024-11-26 | 南昌大学 | 一株脂多糖修饰b群脑膜炎球菌与其外膜囊泡制备及应用 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4601903A (en) | 1985-05-01 | 1986-07-22 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease |
| US4727136A (en) | 1985-10-01 | 1988-02-23 | Canadian Patents And Development Ltd. | Modified meningococcal group B polysaccharide for conjugate vaccine |
| AU640118B2 (en) | 1988-12-19 | 1993-08-19 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur | Meningococcal class 1 outer-membrane protein vaccine |
| US7118757B1 (en) * | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| DE4023721A1 (de) | 1990-07-26 | 1992-01-30 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von vakzinen und ihre verwendung |
| US5552146A (en) | 1991-08-15 | 1996-09-03 | Board Of Regents, The University Of Texas System | Methods and compositions relating to useful antigens of Moraxella catarrhalis |
| NL9201716A (nl) | 1992-10-02 | 1994-05-02 | Nederlanden Staat | Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat. |
| US7112332B1 (en) | 1992-10-08 | 2006-09-26 | The United States Of America As Represented By The Secretary Of The Army | Oral or intranasal vaccines using hydrophobic complexes having proteosomes and lipopolysaccharides |
| DK0624376T3 (da) | 1993-05-13 | 2000-07-24 | American Cyanamid Co | Fremstilling og anvendelse af LOS-udtømte ydre membranproteiner af gram-negative cocci |
| US5961970A (en) | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
| PT854729E (pt) | 1995-09-18 | 2004-08-31 | Us Army Med Res Mat Com Usamrm | Metodos melhorados para a producao de vacinas de subunidade multivalentes de proteossomas complexados nao covalentemente |
| US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
| GB9726398D0 (en) | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
| GB9808866D0 (en) | 1998-04-24 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| US20030215469A1 (en) | 1998-11-02 | 2003-11-20 | Microbiological Research Authority | Multicomponent meningococcal vaccine |
| GB9823978D0 (en) | 1998-11-02 | 1998-12-30 | Microbiological Res Authority | Multicomponent meningococcal vaccine |
| DK1154791T3 (da) | 1999-02-22 | 2008-06-16 | Health Prot Agency | Neisseria-vaccinesammensætninger og fremgangsmåder |
| GB9918319D0 (en) * | 1999-08-03 | 1999-10-06 | Smithkline Beecham Biolog | Vaccine composition |
| ES2588917T3 (es) * | 2000-01-17 | 2016-11-07 | Glaxosmithkline Biologicals Sa | Vacuna de VME suplementada contra meningococo |
| NO20002828D0 (no) | 2000-06-02 | 2000-06-02 | Statens Inst For Folkehelse | Proteinholdig vaksine mot Neisseria meningtidis serogruppe samt fremgangsmÕte ved fremstilling derav |
| EP1946769B1 (en) | 2000-06-29 | 2012-05-30 | SmithKline Beecham Biologicals S.A. | Multivalent vaccine composition with reduced dose of Haemophilus influenzae type B |
| GB0103170D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| GB0024200D0 (en) | 2000-10-03 | 2000-11-15 | Smithkline Beecham Sa | Component vaccine |
| GB0103169D0 (en) | 2001-02-08 | 2001-03-28 | Smithkline Beecham Biolog | Vaccine composition |
| ES2399386T3 (es) | 2001-04-05 | 2013-04-01 | Novartis Vaccines And Diagnostics, Inc. | Aumento de la inmunidad de las mucosas tras sensibilización parenteral |
| GB0130123D0 (en) | 2001-12-17 | 2002-02-06 | Microbiological Res Agency | Outer membrane vesicle vaccine and its preparation |
| EP1374892A1 (en) | 2002-06-28 | 2004-01-02 | Braun, Jan Matthias, Dr. | Medicament for the treatment of diseases due to infection by Neisseria Meningitidis |
| CN1674933B (zh) | 2002-08-02 | 2012-09-26 | 葛兰素史密丝克莱恩生物有限公司 | 疫苗组合物 |
| CU23377A1 (es) | 2003-11-04 | 2009-05-28 | Ct De Ingenieria Genetica Y Biotecnologia | Metodo para la incorporacion de antigenos en vesiculas de membrana externa de bacterias y formulaciones resultantes |
| US7628995B2 (en) | 2003-12-23 | 2009-12-08 | Glaxosmithkline Biologicals S.A. | Outer membrane vesicles and uses thereof |
| ES2344114T3 (es) * | 2004-05-11 | 2010-08-18 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws | Lipooligosacaridos de neisseria meningitidis igtb como adyuvante. |
| US7537766B2 (en) | 2004-08-30 | 2009-05-26 | Wyeth | Neisseria meningitidis inner core lipo-oligosaccharide epitopes, multivalent conjugates thereof and immunogenic compositions thereof |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| CN101107007B (zh) | 2005-01-27 | 2011-08-17 | 奥克兰儿童医院及研究中心 | 对脑膜炎奈瑟球菌所致疾病具有广谱保护作用的gna1870囊泡疫苗 |
| ES2337309T5 (es) * | 2006-06-12 | 2013-07-30 | Glaxosmithkline Biologicals S.A. | Vacuna |
-
2009
- 2009-06-01 MX MX2010012999A patent/MX2010012999A/es unknown
- 2009-06-01 NZ NZ589812A patent/NZ589812A/xx not_active IP Right Cessation
- 2009-06-01 US US12/995,268 patent/US9387239B2/en not_active Expired - Fee Related
- 2009-06-01 JP JP2011511892A patent/JP5723768B2/ja not_active Expired - Fee Related
- 2009-06-01 WO PCT/US2009/045818 patent/WO2009158142A1/en not_active Ceased
- 2009-06-01 UA UAA201015812A patent/UA99659C2/uk unknown
- 2009-06-01 CN CN200980125861XA patent/CN102105166A/zh active Pending
- 2009-06-01 KR KR1020107029750A patent/KR20110053314A/ko not_active Ceased
- 2009-06-01 EP EP09770677.4A patent/EP2296699A4/en not_active Withdrawn
- 2009-06-01 RU RU2010153658/15A patent/RU2477145C2/ru not_active IP Right Cessation
- 2009-06-01 BR BRPI0913268A patent/BRPI0913268A2/pt not_active IP Right Cessation
- 2009-06-01 AU AU2009262893A patent/AU2009262893B2/en not_active Ceased
- 2009-06-01 CA CA2726465A patent/CA2726465A1/en not_active Abandoned
-
2010
- 2010-11-25 CR CR11812A patent/CR11812A/es unknown
- 2010-11-26 DO DO2010000364A patent/DOP2010000364A/es unknown
- 2010-11-29 ZA ZA2010/08548A patent/ZA201008548B/en unknown
- 2010-11-30 IL IL209660A patent/IL209660A0/en unknown
- 2010-12-27 EC EC2010010723A patent/ECSP10010723A/es unknown
- 2010-12-29 CO CO10164103A patent/CO6341569A2/es not_active Application Discontinuation
-
2014
- 2014-12-11 JP JP2014250805A patent/JP2015061870A/ja not_active Withdrawn
-
2016
- 2016-07-12 US US15/208,067 patent/US20170100471A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP5723768B2 (ja) | 2015-05-27 |
| DOP2010000364A (es) | 2011-07-15 |
| US9387239B2 (en) | 2016-07-12 |
| MX2010012999A (es) | 2012-03-07 |
| AU2009262893A9 (en) | 2015-05-21 |
| NZ589812A (en) | 2012-08-31 |
| AU2009262893B2 (en) | 2015-05-21 |
| RU2010153658A (ru) | 2012-08-10 |
| JP2015061870A (ja) | 2015-04-02 |
| ZA201008548B (en) | 2012-06-27 |
| AU2009262893A1 (en) | 2009-12-30 |
| US20170100471A1 (en) | 2017-04-13 |
| CA2726465A1 (en) | 2009-12-30 |
| WO2009158142A1 (en) | 2009-12-30 |
| JP2011521976A (ja) | 2011-07-28 |
| US20110182942A1 (en) | 2011-07-28 |
| CR11812A (es) | 2011-07-06 |
| CN102105166A (zh) | 2011-06-22 |
| EP2296699A4 (en) | 2013-11-13 |
| IL209660A0 (en) | 2011-02-28 |
| ECSP10010723A (es) | 2011-05-31 |
| UA99659C2 (uk) | 2012-09-10 |
| EP2296699A1 (en) | 2011-03-23 |
| BRPI0913268A2 (pt) | 2016-03-15 |
| RU2477145C2 (ru) | 2013-03-10 |
| KR20110053314A (ko) | 2011-05-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX383065B (es) | Mutantes de virus de influenza y usos para los mismos. | |
| EA200900784A1 (ru) | Вакцины, включающие антиген из четырех штаммов вируса гриппа | |
| CO6362045A2 (es) | Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales | |
| DOP2010000364A (es) | Vacuna de vesicula de membrana externa nativa multivalente del miningococo metodo para su fabricacion y uso | |
| CO2018005229A2 (es) | Vacuna de virus sincitial respiratorio | |
| BR112018011122A2 (pt) | antígenos, vetores, composições, e métodos de utilização para o vírus da imunodeficiência humana dos mesmos | |
| CO6761348A2 (es) | Compuestos antivirales | |
| MX392320B (es) | Composiciones inmunogenicas de la glucoproteina g de los virus hendra y nipah. | |
| CL2012000573A1 (es) | Compuestos derivados de bifenil-pirrolidinil-imidazol; composicion farmaceutica que los comprende; su uso en el tratamiento de una infeccion viral por hcv. | |
| BR112013011949A2 (pt) | "indóis, composição farmacêutica que os compreende, seus processos de preparação e uso dos ditos indóis" | |
| EA200801756A1 (ru) | Противогриппозные вакцины, содержащие гемагглютинин и белки матрикса | |
| MX373096B (es) | Formulaciones virales líquidas. | |
| MX349294B (es) | Formulaciones virales liofilizadas. | |
| WO2009115917A3 (en) | Improvements in preparation of influenza virus vaccine antigens | |
| WO2012047267A3 (en) | Polyvalent immunogen | |
| MX2024003337A (es) | Composiciones inmunogenicas contra la influenza. | |
| EA201270577A1 (ru) | Усовершенствованные способы обратной генетики для спасения вирусов | |
| WO2012078051A3 (en) | IPN Vaccine | |
| MX2024003507A (es) | Mutantes del virus de la influenza b y usos de los mismos. | |
| CU20100056A7 (es) | Método para inhibir la replicación del vih en células de mamíferos | |
| BR112015002268A2 (pt) | produção de vírus influenza infecciosos | |
| AR079970A1 (es) | Cepas de alto rendimiento del virus de la fiebre amarilla con una propagacion incrementada en las celulas | |
| BR112019008584A2 (pt) | vacinas de mosaico para vírus de doença de pé-e-boca de sorotipo a | |
| AR065759A1 (es) | Composicion de vacuna y metodos para vacunar un ave | |
| IN2014DN07152A (enExample) |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |