CO6290758A2 - Proceso para la elaboracion de [fenilsulfanilfenil]piperidinas - Google Patents
Proceso para la elaboracion de [fenilsulfanilfenil]piperidinasInfo
- Publication number
- CO6290758A2 CO6290758A2 CO10108740A CO10108740A CO6290758A2 CO 6290758 A2 CO6290758 A2 CO 6290758A2 CO 10108740 A CO10108740 A CO 10108740A CO 10108740 A CO10108740 A CO 10108740A CO 6290758 A2 CO6290758 A2 CO 6290758A2
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- formula
- compound
- preparation
- optionally substituted
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- -1 alkyl lithium Chemical compound 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 239000011777 magnesium Substances 0.000 abstract 2
- SJZKULRDWHPHGG-UHFFFAOYSA-N 1-benzylpiperidin-4-one Chemical class C1CC(=O)CCN1CC1=CC=CC=C1 SJZKULRDWHPHGG-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical group C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000013067 intermediate product Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 238000006263 metalation reaction Methods 0.000 abstract 1
- HDOWRFHMPULYOA-UHFFFAOYSA-N piperidin-4-ol Chemical compound OC1CCNCC1 HDOWRFHMPULYOA-UHFFFAOYSA-N 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200800314 | 2008-03-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6290758A2 true CO6290758A2 (es) | 2011-06-20 |
Family
ID=40547924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO10108740A CO6290758A2 (es) | 2008-03-03 | 2010-09-02 | Proceso para la elaboracion de [fenilsulfanilfenil]piperidinas |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8362255B2 (enExample) |
| EP (1) | EP2260024B1 (enExample) |
| JP (1) | JP5564439B2 (enExample) |
| KR (1) | KR20100122914A (enExample) |
| CN (1) | CN101959859B (enExample) |
| AR (1) | AR070737A1 (enExample) |
| AT (1) | ATE539055T1 (enExample) |
| AU (1) | AU2009221170B2 (enExample) |
| BR (1) | BRPI0908166A2 (enExample) |
| CA (1) | CA2715579A1 (enExample) |
| CL (1) | CL2009000490A1 (enExample) |
| CO (1) | CO6290758A2 (enExample) |
| CY (1) | CY1113887T1 (enExample) |
| DK (1) | DK2260024T3 (enExample) |
| EA (1) | EA017855B1 (enExample) |
| ES (1) | ES2377862T3 (enExample) |
| HR (1) | HRP20120118T1 (enExample) |
| IL (1) | IL207471A (enExample) |
| MX (1) | MX2010008729A (enExample) |
| NZ (1) | NZ587593A (enExample) |
| PL (1) | PL2260024T3 (enExample) |
| PT (1) | PT2260024E (enExample) |
| RS (1) | RS52128B (enExample) |
| SI (1) | SI2260024T1 (enExample) |
| TW (1) | TW200940505A (enExample) |
| UA (1) | UA98698C2 (enExample) |
| WO (1) | WO2009109541A1 (enExample) |
| ZA (1) | ZA201006135B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007260356B2 (en) * | 2006-06-16 | 2013-01-24 | H. Lundbeck A/S | Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
| JP2012163850A (ja) * | 2011-02-08 | 2012-08-30 | Nippon Sheet Glass Co Ltd | 正立等倍レンズアレイプレート、光走査ユニット、画像読取装置および画像書込装置 |
| KR20150013548A (ko) | 2012-05-21 | 2015-02-05 | 노파르티스 아게 | 키나제 억제제로서의 신규 고리-치환된 n-피리디닐 아미드 |
| CN104710345B (zh) * | 2013-12-17 | 2017-09-05 | 江苏恩华药业股份有限公司 | 用于制备4‑（2‑（4‑甲基苯基硫基））苯基哌啶的化合物、其制备方法及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2324087A (en) * | 1997-04-10 | 1998-10-14 | Merck & Co Inc | Preparation of (S)-3-Carbethoxy-3-benzylpiperidine |
| AU1805701A (en) | 1999-12-20 | 2001-07-03 | Eli Lilly And Company | A process for preparing trans-2,4-disubstituted piperidines |
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| UA81300C2 (en) * | 2003-04-04 | 2007-12-25 | Lundbeck & Co As H | Derivates of 4-(2-fenilsulfanilfenil)-1,2,3,6-tetrahydropiridin as retarding agents of serotonin recapture |
| CA2521258C (en) * | 2003-04-04 | 2009-12-01 | H. Lundbeck A/S | 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors |
| AU2007260356B2 (en) * | 2006-06-16 | 2013-01-24 | H. Lundbeck A/S | Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain |
-
2009
- 2009-02-03 UA UAA201011031A patent/UA98698C2/ru unknown
- 2009-02-19 TW TW098105235A patent/TW200940505A/zh unknown
- 2009-03-02 EP EP09717792A patent/EP2260024B1/en active Active
- 2009-03-02 ES ES09717792T patent/ES2377862T3/es active Active
- 2009-03-02 CL CL2009000490A patent/CL2009000490A1/es unknown
- 2009-03-02 JP JP2010549114A patent/JP5564439B2/ja not_active Expired - Fee Related
- 2009-03-02 PT PT09717792T patent/PT2260024E/pt unknown
- 2009-03-02 KR KR1020107019480A patent/KR20100122914A/ko not_active Ceased
- 2009-03-02 AT AT09717792T patent/ATE539055T1/de active
- 2009-03-02 WO PCT/EP2009/052440 patent/WO2009109541A1/en not_active Ceased
- 2009-03-02 PL PL09717792T patent/PL2260024T3/pl unknown
- 2009-03-02 RS RS20120063A patent/RS52128B/sr unknown
- 2009-03-02 AR ARP090100734A patent/AR070737A1/es unknown
- 2009-03-02 NZ NZ587593A patent/NZ587593A/en not_active IP Right Cessation
- 2009-03-02 AU AU2009221170A patent/AU2009221170B2/en not_active Ceased
- 2009-03-02 US US12/920,357 patent/US8362255B2/en not_active Expired - Fee Related
- 2009-03-02 DK DK09717792.7T patent/DK2260024T3/da active
- 2009-03-02 CA CA2715579A patent/CA2715579A1/en not_active Abandoned
- 2009-03-02 MX MX2010008729A patent/MX2010008729A/es active IP Right Grant
- 2009-03-02 SI SI200930184T patent/SI2260024T1/sl unknown
- 2009-03-02 BR BRPI0908166-6A patent/BRPI0908166A2/pt not_active IP Right Cessation
- 2009-03-02 CN CN200980108235XA patent/CN101959859B/zh not_active Expired - Fee Related
- 2009-03-02 HR HR20120118T patent/HRP20120118T1/hr unknown
- 2009-03-02 EA EA201071025A patent/EA017855B1/ru not_active IP Right Cessation
-
2010
- 2010-08-08 IL IL207471A patent/IL207471A/en not_active IP Right Cessation
- 2010-08-27 ZA ZA2010/06135A patent/ZA201006135B/en unknown
- 2010-09-02 CO CO10108740A patent/CO6290758A2/es active IP Right Grant
-
2012
- 2012-02-13 CY CY20121100145T patent/CY1113887T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Application granted |