CO6290706A2 - Combinacion sinergica de un agonista nicotinico alfa 7 y un agente antipsicotico - Google Patents

Combinacion sinergica de un agonista nicotinico alfa 7 y un agente antipsicotico

Info

Publication number
CO6290706A2
CO6290706A2 CO10112124A CO10112124A CO6290706A2 CO 6290706 A2 CO6290706 A2 CO 6290706A2 CO 10112124 A CO10112124 A CO 10112124A CO 10112124 A CO10112124 A CO 10112124A CO 6290706 A2 CO6290706 A2 CO 6290706A2
Authority
CO
Colombia
Prior art keywords
nicotinic agonist
combination
pharmaceutical combination
alfa
antipsychotic agent
Prior art date
Application number
CO10112124A
Other languages
English (en)
Spanish (es)
Inventor
Merouane Bencherif
Gregory J Gatto
Kristen Jordan
Terry Hauser
Sharon R Letchworth
Original Assignee
Targacept Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targacept Inc filed Critical Targacept Inc
Publication of CO6290706A2 publication Critical patent/CO6290706A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
CO10112124A 2008-02-13 2010-09-10 Combinacion sinergica de un agonista nicotinico alfa 7 y un agente antipsicotico CO6290706A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2828208P 2008-02-13 2008-02-13

Publications (1)

Publication Number Publication Date
CO6290706A2 true CO6290706A2 (es) 2011-06-20

Family

ID=40902222

Family Applications (1)

Application Number Title Priority Date Filing Date
CO10112124A CO6290706A2 (es) 2008-02-13 2010-09-10 Combinacion sinergica de un agonista nicotinico alfa 7 y un agente antipsicotico

Country Status (25)

Country Link
US (1) US20110059947A1 (enExample)
EP (2) EP2633868A1 (enExample)
JP (1) JP2011511845A (enExample)
KR (1) KR20100113163A (enExample)
CN (2) CN101977628A (enExample)
AU (1) AU2009214625A1 (enExample)
BR (1) BRPI0907570A2 (enExample)
CA (1) CA2715268A1 (enExample)
CO (1) CO6290706A2 (enExample)
CY (1) CY1114492T1 (enExample)
DK (1) DK2254598T3 (enExample)
EC (1) ECSP10010471A (enExample)
ES (1) ES2430622T3 (enExample)
HR (1) HRP20130749T1 (enExample)
IL (1) IL207389A0 (enExample)
MX (1) MX2010008875A (enExample)
NZ (1) NZ587312A (enExample)
PL (1) PL2254598T3 (enExample)
PT (1) PT2254598E (enExample)
RS (1) RS52941B (enExample)
RU (1) RU2481123C2 (enExample)
SG (1) SG188144A1 (enExample)
SI (1) SI2254598T1 (enExample)
WO (1) WO2009102962A2 (enExample)
ZA (1) ZA201005999B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8314119B2 (en) 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
SA08290475B1 (ar) * 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
MX2013003344A (es) 2010-09-23 2013-06-28 Abbvie Inc Monohidrato de un derivado de azaadamantano.
PH12013501509A1 (en) * 2011-01-18 2019-08-07 Targacept Inc Treatment of cognitive dysfunction in schizophrenia
EP2704573A4 (en) * 2011-05-03 2014-10-15 Merck Sharp & Dohme AMINOMETHYL biaryl BENZOTRIAZOL DERIVATIVES
CN104837820A (zh) * 2012-10-02 2015-08-12 大日本住友制药株式会社 咪唑衍生物
JP6807094B2 (ja) * 2016-04-29 2021-01-06 国立大学法人秋田大学 クロザピン又はその誘導体の血中薬剤濃度上昇リスク判定方法及び薬剤投与量判定方法
WO2018115001A1 (en) 2016-12-20 2018-06-28 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine
RU2764443C2 (ru) 2016-12-20 2022-01-17 Лтс Ломанн Терапи-Систем Аг Трансдермальная терапевтическая система, содержащая азенапин и полисилоксан или полиизобутилен
CN108727416B (zh) * 2017-04-20 2021-03-09 北京大学 三环杂芳香体系酰胺衍生物及其制备和用途
CN110799180A (zh) 2017-06-26 2020-02-14 罗曼治疗系统股份公司 含阿塞那平和硅氧烷丙烯酸杂化聚合物的经皮治疗系统
CN107469087A (zh) * 2017-09-10 2017-12-15 孙永丽 用于治疗精神病的制剂
AU2019291060B2 (en) 2018-06-20 2024-09-05 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine
CN112533593A (zh) 2018-06-20 2021-03-19 罗曼治疗系统股份公司 含有阿塞那平的透皮治疗系统
EP4274824A1 (en) 2021-01-08 2023-11-15 IFM Due, Inc. Heterobicyclic compounds having an urea or analogue and their compositions for treating conditions associated with sting activity
EP4274660A1 (en) * 2021-01-08 2023-11-15 IFM Due, Inc. Compounds and compositions for treating conditions associated with sting activity
DE102022114269A1 (de) 2022-06-07 2023-12-07 Rational Aktiengesellschaft Gargerät mit einem Selbstreinigungssystem sowie ein Verfahren zum Ändern von Reinigungsparametern für das Gargerät

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5597919A (en) * 1995-01-06 1997-01-28 Dull; Gary M. Pyrimidinyl or Pyridinyl alkenyl amine compounds
US5712270A (en) 1995-11-06 1998-01-27 American Home Products Corporation 2-arylamidothiazole derivatives with CNS activity
US5616716A (en) 1996-01-06 1997-04-01 Dull; Gary M. (3-(5-ethoxypyridin)yl)-alkenyl 1 amine compounds
SE9600683D0 (sv) 1996-02-23 1996-02-23 Astra Ab Azabicyclic esters of carbamic acids useful in therapy
US5663356A (en) * 1996-04-23 1997-09-02 Ruecroft; Graham Method for preparation of aryl substituted alefinic secondary amino compounds
AR013184A1 (es) 1997-07-18 2000-12-13 Astrazeneca Ab Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis
WO1999062505A2 (en) 1998-06-01 1999-12-09 Ortho-Mcneil Pharmaceutical, Inc. Method for treating neurodegenerative disorders
US6953855B2 (en) * 1998-12-11 2005-10-11 Targacept, Inc. 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof
SE9904176D0 (sv) 1999-11-18 1999-11-18 Astra Ab New use
JP5557409B2 (ja) * 1999-12-10 2014-07-23 ワイス・エルエルシー （ｓ）−２−（ベンジルアミノメチル）−２，３，８，９−テトラヒドロ−７ｈ−１，４−ジオキシノ（２，３）ｅインドール−８−オンと神経遮断薬との組合せ
KR100751981B1 (ko) * 2000-06-27 2007-08-28 라보라토리오스 살바트, 에스.에이. 아릴알킬아민으로부터 유도된 카바메이트
WO2002016357A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
WO2002016356A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
WO2002016358A2 (en) 2000-08-18 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
EP1311505A2 (en) 2000-08-21 2003-05-21 PHARMACIA & UPJOHN COMPANY Quinuclidine-substituted heteroaryl moieties for treatment of disease ( nicotinic acetylcholine receptor ligands )
WO2002017358A2 (en) 2000-08-21 2002-02-28 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease (nicotinic acetylcholine receptor antagonists)
US6599916B2 (en) 2000-08-21 2003-07-29 Pharmacia & Upjohn Company Quinuclidine-substituted heteroaryl moieties for treatment of disease
US6554086B1 (en) * 2000-10-27 2003-04-29 Invacare Corporation Obstacle traversing wheelchair
EP1345937B1 (en) 2000-12-22 2005-09-28 Almirall Prodesfarma AG Quinuclidine carbamate derivatives and their use as m3 antagonists
CA2476624A1 (en) * 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Azabicyclic compounds for the treatment of disease
CN1720248A (zh) * 2002-12-06 2006-01-11 法玛西雅厄普约翰有限责任公司 1－氮杂双环[2.2.2]八取代的呋喃并[2,3－c]吡啶基甲酰胺的晶体富马酸盐及其组合物和制备方法
TW200502222A (en) * 2003-04-02 2005-01-16 Novartis Ag Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders
WO2004099202A1 (en) * 2003-05-05 2004-11-18 Pharmacia & Upjohn Company Llc Quinuclidines substituted bentodioxine carboxamides for the treatment of neurodegenerative diseases
US7309699B2 (en) * 2003-12-22 2007-12-18 Abbott Laboratories 3-Quinuclidinyl amino-substituted biaryl derivatives
EP1699488A2 (en) * 2003-12-23 2006-09-13 Pfizer Products Incorporated Therapeutic combination for cognition enhancement and psychotic disorders
MX2007011436A (es) * 2005-03-18 2007-10-12 Abbott Lab Ligando del receptor nicotinico neuronal 7 y composiciones antipsicoticas.

Also Published As

Publication number Publication date
EP2254598B1 (en) 2013-07-10
JP2011511845A (ja) 2011-04-14
ECSP10010471A (es) 2010-10-30
CN101977628A (zh) 2011-02-16
WO2009102962A3 (en) 2009-10-08
RU2010137787A (ru) 2012-03-20
CN103143023A (zh) 2013-06-12
PT2254598E (pt) 2013-10-16
BRPI0907570A2 (pt) 2019-09-24
DK2254598T3 (da) 2013-07-29
IL207389A0 (en) 2010-12-30
HRP20130749T1 (en) 2013-10-11
EP2633868A1 (en) 2013-09-04
PL2254598T3 (pl) 2013-12-31
RS52941B (sr) 2014-02-28
HK1147954A1 (en) 2011-08-26
EP2254598A2 (en) 2010-12-01
CY1114492T1 (el) 2016-10-05
US20110059947A1 (en) 2011-03-10
SI2254598T1 (sl) 2013-10-30
RU2481123C2 (ru) 2013-05-10
NZ587312A (en) 2011-12-22
WO2009102962A2 (en) 2009-08-20
ZA201005999B (en) 2011-05-25
ES2430622T3 (es) 2013-11-21
AU2009214625A1 (en) 2009-08-20
MX2010008875A (es) 2010-08-31
CA2715268A1 (en) 2009-08-20
SG188144A1 (en) 2013-03-28
KR20100113163A (ko) 2010-10-20

Similar Documents

Publication Publication Date Title
CO6290706A2 (es) Combinacion sinergica de un agonista nicotinico alfa 7 y un agente antipsicotico
CL2011000091A1 (es) Formulacion farmaceutica que comprende trans-1{4-[2-[4-(2,3-diclorofenil)-piperazin-1-il]etil]-ciclohexil}-3,3-dimetil-urea, en la cual la formulacion comprende menos del 1% de trans 4-[2-[4-(2,3-diclorofenil)-piperazin-1-il]etil]-ciclohexil-amina o una sal; uso en esquizofrenia, trastorno bipolar y mania aguda.
CY1120961T1 (el) Δοσολογικες μορφες απο του στοματος που περιλαμβανουν αντιαιμοπεταλιακο παραγοντα και αναστολεα οξεος
CL2011000916A1 (es) Uso de una combinacion de un inhibidor de proteasoma epoxicetona peptidica o una sal farmaceutica aceptable del mismo, y uno o mas de otros agentes terapeuticos para tratar el cancer.
CL2011001811A1 (es) Un metodo para tratar un paciente que ha sufrido un infarto agudo al miocardio que comprende el uso de un agente antifibrotico.
CR20120345A (es) Derivados de 3-hidroxi-5-arilisotiazol novedosos
MY155275A (en) 4-(4-[6-(trifluoromethyl-pyridin-3-ylamino)-n-containing-heteroaryl]-phenyl)-cyclohexyl)-acetic acid derivatives and pharmaceutical uses thereof
CL2012002706A1 (es) Composicion farmaceutica termogelificante estabilizada compuesta por anestesicos locales con un ph de al menos el pka de dichos anestesicos, que comprende a) la forma basica de uno o mas anestesicos de tipo amida, b) 10 a 30% de un aceite de ricino polioxietilado, y c) al menos 15% de uno o mas tensioactivos; y su metodo de preparacion.
CR11369A (es) Anticuerpo anti-glipican-3 que tiene cineticas mejoradas en el plasma
EA200870376A1 (ru) Бензотиазолы, обладающие активностью по отношению к h3-рецептору гистамина
CL2008003902A1 (es) Formulación farmacéutica que comprende tetrahidrocannabidivirina (thcv) y/o cannabidiol (cbd) junto a aripiprazol o un metabolito del mismo y su uso en la prevención o el tratamiento de la psicosis o de un trastorno psicótico.
CL2011000454A1 (es) Compuestos derivados de picolinamida, inhibidores de quinasa pim, asociada a tumorigenesis; composicion farmaceutica que los comprende; y su uso en el tratamiento del cancer.
CL2010001160A1 (es) Compuestos derivados de 3,8-diazabiciclo[4.2.0]octano y 3,6-diazabiciclo[3.2.0]heptano; composicion farmaceutica; moduladores del reeptor de la orexina, utiles en el tratamiento del insomnio.
CL2008001038A1 (es) Uso de una composicion que comprende un antagonosta h1, y un compuesto anti-tnf alfa para tratar conjuntivitis alegica o rinitis alergiva en un sujeto humano
CL2014002406A1 (es) Metodo para el tratamiento de la depresion refractaria o resistente al taratamiento que comprende administrar esketamina por via intravenosa o intranasal sola o en combinacion con uno o mas antidepresivos; composicion farmaceutica; y su uso en el tratamiento de la depresion refractaria o resistente al tratamiento.
CL2008002042A1 (es) Compuestos derivados de heterociclos nitrogenados enlazados; y su uso en el tratamiento de la diabetes y desordenes metabolicos.
UY30892A1 (es) Inhibidores de la actividad akt
ES2564172T3 (es) Utilización de una composición cosmética para el cuidado de las pieles grasas
NZ604592A (en) Combinations comprising atypical antipsychotics and taar1 agonists
BR112015023439A2 (pt) combinação de tratamentos de câncer utilizando micrornas e inibidores egfr-tki
CL2011000798A1 (es) Uso de etexilato de dabigatran o una sal del mismo para preparar un medicamento util para la prevencion del ictus en pacientes que padecen fibrilacion auricular.
DOP2019000232A (es) Moduladores de la expresión de pcsk9
CL2008002049A1 (es) Compuestos derivados de aminoindol macrociclicos; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c.
ECSP088555A (es) Composiciones farmacéuticas
PL383715A1 (pl) Amidy kwasu 3-arylo-3-hydroksy-2-amino-propionowego, amidy kwasu 3-heteroarylo-3-hydroksy-2-amino-propionowego i ich związki pokrewne posiadające aktywność przeciwbólową i/lub pobudzającą odporność

Legal Events

Date Code Title Description
FC Application refused