CO5630027A2 - Agentes terapeuticos derivados de acido 3-fenilpropionico sustituido - Google Patents
Agentes terapeuticos derivados de acido 3-fenilpropionico sustituidoInfo
- Publication number
- CO5630027A2 CO5630027A2 CO06001010A CO06001010A CO5630027A2 CO 5630027 A2 CO5630027 A2 CO 5630027A2 CO 06001010 A CO06001010 A CO 06001010A CO 06001010 A CO06001010 A CO 06001010A CO 5630027 A2 CO5630027 A2 CO 5630027A2
- Authority
- CO
- Colombia
- Prior art keywords
- aryl
- alkyl
- alkylaryl
- substituted
- therapeutic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Abstract
1.- Un compuesto de fórmula I y sus sales farmacéuticamente aceptables, en la cual A se sitúa en la posición para y representa A1 ó A2 a continuaciónen donde R es hidrógeno;-ORa, en donde Ra representa hidrógeno, alquilo, arilo o alquilarilo;-NRaRb, en donde Ra y Rb son los mismos o diferentes y Ra es como se define anteriormente y Rb representa hidrógeno, alquilo, arilo, alquilarilo, ciano, -OH, -Oalquilo, -Oarilo, -Oalquilarilo, -CORc ó -SO2Rd, en donde Rc representa hidrógeno, alquilo, arilo o alquilarilo y Rd representa alquilo, arilo o alquilarilo;R1 es alquilo, arilo, alquenilo, alquinilo, ciano;-ORe, en donde Re es alquilo, acilo, arilo o alquilarilo;-O-[CH2]m -ORf, en donde Rf representa hidrógeno, alquilo, acilo, arilo o alquilarilo y m representa un entero 1-8;-OCONRaRc, en donde Ra y Rc son como se definen anteriormente;-SRd, en donde Rd es como se define anteriormente; ...
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0314075.3A GB0314075D0 (en) | 2003-06-18 | 2003-06-18 | Therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
CO5630027A2 true CO5630027A2 (es) | 2006-04-28 |
Family
ID=27636748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO06001010A CO5630027A2 (es) | 2003-06-18 | 2006-01-05 | Agentes terapeuticos derivados de acido 3-fenilpropionico sustituido |
Country Status (21)
Country | Link |
---|---|
US (1) | US20060199857A1 (es) |
EP (1) | EP1638927A1 (es) |
JP (1) | JP2006527747A (es) |
KR (1) | KR20060023994A (es) |
CN (1) | CN1835917A (es) |
AR (1) | AR044828A1 (es) |
AU (1) | AU2004249474B2 (es) |
BR (1) | BRPI0411536A (es) |
CA (1) | CA2529297A1 (es) |
CO (1) | CO5630027A2 (es) |
GB (1) | GB0314075D0 (es) |
IL (1) | IL172632A0 (es) |
IS (1) | IS8227A (es) |
MX (1) | MXPA05013719A (es) |
NO (1) | NO20056005L (es) |
RU (1) | RU2005141062A (es) |
SA (1) | SA04250193B1 (es) |
TW (1) | TW200503999A (es) |
UY (1) | UY28370A1 (es) |
WO (1) | WO2004113282A1 (es) |
ZA (1) | ZA200510260B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0104333D0 (sv) | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
DK1517883T3 (da) | 2002-06-20 | 2008-05-26 | Astrazeneca Ab | Ortho-substituerede benzoesyrederivater til behandling af insulinresistens |
GB0314131D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
GB0427524D0 (en) | 2004-12-16 | 2005-01-19 | Astrazeneca Ab | Chemical process |
KR101343443B1 (ko) * | 2010-02-18 | 2013-12-19 | 재단법인 아산사회복지재단 | 콜키친 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조 방법 및 이를 포함하는 약학 조성물 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU170228B (es) * | 1974-04-19 | 1977-04-28 | ||
SE9801990D0 (sv) * | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl propionic acid derivatives and analogs |
SE9801992D0 (sv) * | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl-2-hydroxypropionic acid derivative I |
MA26634A1 (fr) * | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
BR0210190A (pt) * | 2001-06-07 | 2004-04-06 | Lilly Co Eli | Moduladores de receptores ativados de proliferador de peroxissomo |
UA82835C2 (en) * | 2001-12-03 | 2008-05-26 | Reddys Lab Ltd Dr | ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon |
SE0104333D0 (sv) * | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
GB0314130D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
GB0314131D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
GB0314260D0 (en) * | 2003-06-19 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
-
2003
- 2003-06-18 GB GBGB0314075.3A patent/GB0314075D0/en not_active Ceased
-
2004
- 2004-06-07 TW TW093116337A patent/TW200503999A/zh unknown
- 2004-06-16 CA CA002529297A patent/CA2529297A1/en not_active Abandoned
- 2004-06-16 KR KR1020057024377A patent/KR20060023994A/ko not_active Application Discontinuation
- 2004-06-16 US US10/561,126 patent/US20060199857A1/en not_active Abandoned
- 2004-06-16 RU RU2005141062/04A patent/RU2005141062A/ru not_active Application Discontinuation
- 2004-06-16 MX MXPA05013719A patent/MXPA05013719A/es unknown
- 2004-06-16 WO PCT/GB2004/002554 patent/WO2004113282A1/en active Application Filing
- 2004-06-16 CN CNA2004800232732A patent/CN1835917A/zh active Pending
- 2004-06-16 JP JP2006516423A patent/JP2006527747A/ja active Pending
- 2004-06-16 AU AU2004249474A patent/AU2004249474B2/en not_active Expired - Fee Related
- 2004-06-16 EP EP04736926A patent/EP1638927A1/en not_active Withdrawn
- 2004-06-16 BR BRPI0411536-8A patent/BRPI0411536A/pt not_active IP Right Cessation
- 2004-06-17 UY UY28370A patent/UY28370A1/es not_active Application Discontinuation
- 2004-06-18 AR ARP040102138A patent/AR044828A1/es not_active Application Discontinuation
- 2004-06-30 SA SA04250193A patent/SA04250193B1/ar unknown
-
2005
- 2005-01-11 IS IS8227A patent/IS8227A/is unknown
- 2005-12-15 IL IL172632A patent/IL172632A0/en unknown
- 2005-12-15 ZA ZA200510260A patent/ZA200510260B/en unknown
- 2005-12-16 NO NO20056005A patent/NO20056005L/no not_active Application Discontinuation
-
2006
- 2006-01-05 CO CO06001010A patent/CO5630027A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2529297A1 (en) | 2004-12-29 |
CN1835917A (zh) | 2006-09-20 |
KR20060023994A (ko) | 2006-03-15 |
AU2004249474B2 (en) | 2008-05-15 |
IS8227A (is) | 2006-01-10 |
JP2006527747A (ja) | 2006-12-07 |
US20060199857A1 (en) | 2006-09-07 |
BRPI0411536A (pt) | 2006-08-01 |
TW200503999A (en) | 2005-02-01 |
AR044828A1 (es) | 2005-10-05 |
WO2004113282A1 (en) | 2004-12-29 |
EP1638927A1 (en) | 2006-03-29 |
GB0314075D0 (en) | 2003-07-23 |
UY28370A1 (es) | 2005-01-31 |
RU2005141062A (ru) | 2006-07-10 |
ZA200510260B (en) | 2007-01-31 |
MXPA05013719A (es) | 2006-06-27 |
NO20056005L (no) | 2006-02-24 |
SA04250193B1 (ar) | 2007-08-13 |
IL172632A0 (en) | 2006-04-10 |
AU2004249474A1 (en) | 2004-12-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20040636A1 (es) | Ester de 2'-c-metil-3'-o-l-valina de ribofuranosilcitidina | |
CO5150182A1 (es) | Compuestos de triazol y su utilizacion | |
CY1113657T1 (el) | Νεα παραγωγα βενζοφαινονης ή αλατα αυτων | |
ECSP088550A (es) | Nuevos compuestos que son inhibidores de erk | |
DE60331187D1 (de) | Kinaseinhibitoren | |
CO5630027A2 (es) | Agentes terapeuticos derivados de acido 3-fenilpropionico sustituido | |
EA200600348A1 (ru) | Новые соединения | |
DE60306398D1 (de) | Gasgenerator | |
CY1105790T1 (el) | Νεα μεθοδος για τη συνθεση πepιντοπριλ και των φαρμακευτικως αποδεκτων αλατων αυτου | |
AR039172A1 (es) | Derivados de morfolina, antagonistas de ccr3. | |
UY27236A1 (es) | Inhibidores de pcp basados en ácidos 3-heterociclilpropanohidroxámicos | |
DE60302554D1 (de) | Gasgenerator | |
EA199901098A1 (ru) | Новый способ | |
EA200600898A1 (ru) | Новый способ синтеза периндоприла и его фармацевтически приемлемых солей | |
EA200501900A1 (ru) | Новый способ синтеза периндоприла и его фармацевтически приемлемых солей | |
DE60225595D1 (de) | Herstellung von siliziumverbrückten metallocenverbindungen | |
ECSP045291A (es) | Preparación de ácido n1-(2'-piridil)-1,2-propanodiamino sulfámico y su uso en la síntesis de piperazinas biológicamente activas | |
EA200501925A1 (ru) | Новый способ синтеза периндоприла и его фармацевтически приемлемых солей | |
CY1105699T1 (el) | Νεες φαρμακευτικες ενωσεις με αλφα2υποδοχεα δραστηριοτητας | |
DE60323748D1 (de) | 1,3-diaza-dibenzoazulene als inhibitoren der produfür deren herstellung | |
EA200600454A1 (ru) | Новый способ синтеза периндоприла и его фармацевтически приемлемых солей | |
CY1105789T1 (el) | Νεα μεθοδος για τη συνθεση πepιντοπριλ και των φαρμακευτικως αποδεκτων αλατων αυτου | |
ITMI992423A0 (it) | Procedimento di sintesi diretta di fosfuro di indio | |
ES2286154T3 (es) | Derivados de 5-amino-1-penten-3-ol sustituidos. | |
AR042740A1 (es) | Diazepanes farmaceuticamente activos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Application refused |