CO5550493A2 - Formacion de multiplex de acidos nucleicos - Google Patents
Formacion de multiplex de acidos nucleicosInfo
- Publication number
- CO5550493A2 CO5550493A2 CO04003755A CO04003755A CO5550493A2 CO 5550493 A2 CO5550493 A2 CO 5550493A2 CO 04003755 A CO04003755 A CO 04003755A CO 04003755 A CO04003755 A CO 04003755A CO 5550493 A2 CO5550493 A2 CO 5550493A2
- Authority
- CO
- Colombia
- Prior art keywords
- multiplex
- watson
- base pair
- rules
- crick
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/885,731 US6927027B2 (en) | 1999-12-21 | 2001-06-20 | Nucleic acid multiplex formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO5550493A2 true CO5550493A2 (es) | 2005-08-31 |
Family
ID=25387577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO04003755A CO5550493A2 (es) | 2001-06-20 | 2004-01-20 | Formacion de multiplex de acidos nucleicos |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6927027B2 (https=) |
| EP (1) | EP1436415B1 (https=) |
| JP (1) | JP2004534541A (https=) |
| KR (1) | KR100699960B1 (https=) |
| CN (1) | CN1533441A (https=) |
| AU (1) | AU2002304318B2 (https=) |
| BR (1) | BR0210544A (https=) |
| CA (1) | CA2450831A1 (https=) |
| CO (1) | CO5550493A2 (https=) |
| IL (1) | IL159309A0 (https=) |
| MX (1) | MXPA03012071A (https=) |
| NZ (1) | NZ530647A (https=) |
| RU (1) | RU2304168C2 (https=) |
| WO (1) | WO2002103051A2 (https=) |
| ZA (1) | ZA200400372B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6656692B2 (en) * | 1999-12-21 | 2003-12-02 | Ingeneus Corporation | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
| US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
| JP4616988B2 (ja) * | 2000-12-20 | 2011-01-19 | 株式会社アイシン・コスモス研究所 | 三本鎖ｄｎａ形成技術を応用したｄｎａ多型検出方法 |
| CA2501144C (en) * | 2002-10-23 | 2015-10-06 | University Of Utah Research Foundation | Amplicon melting analysis with saturation dyes |
| US20040142329A1 (en) * | 2003-01-17 | 2004-07-22 | Ingeneus Corporation | Probe conjugation to increase multiplex binding motif preference |
| GB0310270D0 (en) * | 2003-05-03 | 2003-06-11 | Univ Edinburgh | Biomolecular devices |
| US20050249669A1 (en) * | 2003-10-22 | 2005-11-10 | Academia Sinica | Quadruplex stabilizer |
| AU2005218507A1 (en) * | 2004-02-28 | 2005-09-15 | Chang-Ning J. Wang | Nucleic acid complexes |
| US9657347B2 (en) | 2004-04-20 | 2017-05-23 | University of Utah Research Foundation and BioFire Defense, LLC | Nucleic acid melting analysis with saturation dyes |
| NZ554538A (en) | 2004-09-24 | 2009-12-24 | Ingeneus Inc | Genomic assay |
| WO2006124089A1 (en) * | 2005-05-12 | 2006-11-23 | The Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University | Self-assembled nucleic acid nanoarrays and uses therefor |
| WO2007084380A2 (en) * | 2006-01-13 | 2007-07-26 | California Institute Of Technology | Compounds and methods for nucleic acid mismatch detection |
| US7943591B2 (en) | 2007-05-11 | 2011-05-17 | Adynxx, Inc. | Gene expression and pain |
| CN101587066B (zh) * | 2008-05-23 | 2011-03-30 | 中国科学院化学研究所 | 菁染料在检测g-四链体结构dna中的新用途 |
| RU2429293C1 (ru) * | 2009-12-15 | 2011-09-20 | Общество С Ограниченной Ответственностью "Апто-Фарм" | Днк-аптамеры, ингибирующие тромбин, и способ стабилизации их структуры |
| PT2846839T (pt) | 2012-05-10 | 2019-05-29 | Adynxx Inc | Formulações para a administração de ingredientes ativos |
| RU2017108238A (ru) | 2014-08-15 | 2018-09-17 | Эйдинкс, Инк. | Олигонуклеотиды-приманки для лечения боли |
| WO2016057597A1 (en) * | 2014-10-09 | 2016-04-14 | Albert Einstein College Of Medicine, Inc. | Programmed cargo release using nucleic acid-stabilized micelles |
| CN105861682B (zh) * | 2016-05-05 | 2020-06-26 | 厦门多维生物医药科技有限公司 | 鸟嘌呤检测探针 |
| CN110951836B (zh) * | 2019-12-03 | 2023-05-23 | 华东师范大学 | 一种基于光化学调控核酸分子链置换动力学的方法 |
| CN114539422B (zh) * | 2020-11-25 | 2024-03-29 | 安升（上海）医药科技有限公司 | 核酸多聚化介导的多价蛋白药物和疫苗的构建方法及应用 |
| CN113862337B (zh) * | 2021-10-15 | 2023-09-19 | 华东师范大学 | 一种基于冻融循环提高dna链置换反应速率的调控方法 |
| JP7514460B2 (ja) * | 2022-03-31 | 2024-07-11 | 邦明 長峯 | ポリアミンの検出方法、ポリアミンの検出試薬及びアプタマ |
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| US4220450A (en) | 1978-04-05 | 1980-09-02 | Syva Company | Chemically induced fluorescence immunoassay |
| FR2558172B1 (fr) | 1984-01-16 | 1986-06-13 | Inst Nat Sante Rech Med | Sonde contenant un acide nucleique modifie et reconnaissance par des anticorps specifiques et utilisation de cette sonde et de ces anticorps specifiques pour detecter et caracteriser une sequence d'adn homologue |
| FI71768C (fi) * | 1984-02-17 | 1987-02-09 | Orion Yhtymae Oy | Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning. |
| US5011769A (en) | 1985-12-05 | 1991-04-30 | Meiogenics U.S. Limited Partnership | Methods for detecting nucleic acid sequences |
| US4876187A (en) | 1985-12-05 | 1989-10-24 | Meiogenics, Inc. | Nucleic acid compositions with scissile linkage useful for detecting nucleic acid sequences |
| US5928863A (en) | 1986-11-26 | 1999-07-27 | Princeton University | Triple-stranded nucleic acids |
| US5874555A (en) | 1987-10-30 | 1999-02-23 | California Institute Of Technology | Triple helices and processes for making same |
| US5403711A (en) | 1987-11-30 | 1995-04-04 | University Of Iowa Research Foundation | Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved |
| WO1990002204A1 (en) | 1988-08-31 | 1990-03-08 | Research Development Foundation | Manual in situ hybridization assay |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
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| US5824477A (en) | 1990-09-12 | 1998-10-20 | Scientific Generics Limited | Electrochemical denaturation of double-stranded nucleic acid |
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| US6048690A (en) | 1991-11-07 | 2000-04-11 | Nanogen, Inc. | Methods for electronic fluorescent perturbation for analysis and electronic perturbation catalysis for synthesis |
| US5558998A (en) | 1992-02-25 | 1996-09-24 | The Regents Of The Univ. Of California | DNA fragment sizing and sorting by laser-induced fluorescence |
| US5332659A (en) | 1992-04-09 | 1994-07-26 | The United States Of America As Represented By The Secretary Of The Navy | Light emission-or absorbance-based binding assays for polynucleic acids |
| JPH06153997A (ja) | 1992-11-27 | 1994-06-03 | Canon Inc | 検出信号増幅による標的核酸の検出方法 |
| US6027880A (en) | 1995-08-02 | 2000-02-22 | Affymetrix, Inc. | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis |
| US5861124A (en) | 1993-07-15 | 1999-01-19 | Hamamatsu Photonics Kk | Method and apparatus for detecting denaturation of nucleic acid |
| CA2169837A1 (en) | 1993-08-18 | 1995-02-23 | Peter D. Duck | Compositions and methods for detecting target nucleic acid sequences utilizing adjacent sequence-enzyme molecules |
| ATE227342T1 (de) | 1993-09-02 | 2002-11-15 | Ribozyme Pharm Inc | Enzymatische nukleiksaüre die nicht-nukleotide enthaltet |
| US5538848A (en) | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| WO1995014106A2 (en) | 1993-11-17 | 1995-05-26 | Id Biomedical Corporation | Cycling probe cleavage detection of nucleic acid sequences |
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| JP3189000B2 (ja) | 1994-12-01 | 2001-07-16 | 東ソー株式会社 | 特定核酸配列の検出方法 |
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| SE506700C2 (sv) | 1996-05-31 | 1998-02-02 | Mikael Kubista | Sond och förfaranden för analys av nukleinsyra |
| US5948897A (en) | 1996-06-14 | 1999-09-07 | Simon Fraser University | Method of binding two or more DNA double helices and products formed |
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| US6013442A (en) | 1997-08-05 | 2000-01-11 | Wisconsin Alumni Res Found | Direct quantitation of low copy number RNA |
| AU1388199A (en) * | 1997-11-10 | 1999-05-31 | Princeton University | Triplex in-situ hybridization |
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| US6017709A (en) | 1998-04-29 | 2000-01-25 | University Of Houston | DNA replication templates stabilized by guanine quartets |
| US6255469B1 (en) | 1998-05-06 | 2001-07-03 | New York University | Periodic two and three dimensional nucleic acid structures |
| US6255050B1 (en) | 1998-05-22 | 2001-07-03 | Lorne Park Research, Inc. | Dynamic hybridization system |
| GB9812768D0 (en) | 1998-06-13 | 1998-08-12 | Zeneca Ltd | Methods |
| GB9821989D0 (en) | 1998-10-08 | 1998-12-02 | Hybaid Ltd | Detection of nucleic acid polymorphism |
| US6656692B2 (en) * | 1999-12-21 | 2003-12-02 | Ingeneus Corporation | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
| US6900300B1 (en) * | 2000-09-19 | 2005-05-31 | Ingeneus Corporation | Quadruplex DNA and duplex probe systems |
| US6420115B1 (en) * | 1999-12-21 | 2002-07-16 | Ingeneus Corporation | Cation mediated triplex hybridization assay |
| WO2000043543A1 (en) | 1999-01-19 | 2000-07-27 | Dade Behring Inc. | Detection of differences between polynucleotides |
| WO2001024046A2 (en) * | 1999-09-29 | 2001-04-05 | Xml-Global Technologies, Inc. | Authoring, altering, indexing, storing and retrieving electronic documents embedded with contextual markup |
| US6265170B1 (en) | 2000-01-24 | 2001-07-24 | Ingeneus Corporation | Homogenous assay of duplex of triplex hybridization by means of multiple measurements under varied conditions |
-
2001
- 2001-06-20 US US09/885,731 patent/US6927027B2/en not_active Expired - Fee Related
-
2002
- 2002-05-31 EP EP02733104A patent/EP1436415B1/en not_active Expired - Lifetime
- 2002-05-31 WO PCT/IB2002/001972 patent/WO2002103051A2/en not_active Ceased
- 2002-05-31 CN CNA028124103A patent/CN1533441A/zh active Pending
- 2002-05-31 MX MXPA03012071A patent/MXPA03012071A/es active IP Right Grant
- 2002-05-31 IL IL15930902A patent/IL159309A0/xx unknown
- 2002-05-31 KR KR1020037016650A patent/KR100699960B1/ko not_active Expired - Fee Related
- 2002-05-31 AU AU2002304318A patent/AU2002304318B2/en not_active Ceased
- 2002-05-31 RU RU2004101294/13A patent/RU2304168C2/ru not_active IP Right Cessation
- 2002-05-31 NZ NZ530647A patent/NZ530647A/en active IP Right Revival
- 2002-05-31 CA CA002450831A patent/CA2450831A1/en not_active Abandoned
- 2002-05-31 JP JP2003505372A patent/JP2004534541A/ja active Pending
- 2002-05-31 BR BR0210544-6A patent/BR0210544A/pt not_active IP Right Cessation
-
2004
- 2004-01-19 ZA ZA200400372A patent/ZA200400372B/en unknown
- 2004-01-20 CO CO04003755A patent/CO5550493A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2004101294A (ru) | 2005-02-27 |
| CN1533441A (zh) | 2004-09-29 |
| BR0210544A (pt) | 2005-05-31 |
| AU2002304318B2 (en) | 2007-07-26 |
| WO2002103051A2 (en) | 2002-12-27 |
| HK1067666A1 (en) | 2005-04-15 |
| IL159309A0 (en) | 2004-06-01 |
| EP1436415B1 (en) | 2012-08-22 |
| RU2304168C2 (ru) | 2007-08-10 |
| ZA200400372B (en) | 2004-08-23 |
| KR100699960B1 (ko) | 2007-03-27 |
| JP2004534541A (ja) | 2004-11-18 |
| US6927027B2 (en) | 2005-08-09 |
| NZ530647A (https=) | 2005-12-23 |
| WO2002103051A3 (en) | 2004-04-29 |
| EP1436415A2 (en) | 2004-07-14 |
| MXPA03012071A (es) | 2004-06-03 |
| CA2450831A1 (en) | 2002-12-27 |
| US20030113716A1 (en) | 2003-06-19 |
| KR20040019312A (ko) | 2004-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |