BR0210544A - Formação de multiplex de ácido nucleico - Google Patents
Formação de multiplex de ácido nucleicoInfo
- Publication number
- BR0210544A BR0210544A BR0210544-6A BR0210544A BR0210544A BR 0210544 A BR0210544 A BR 0210544A BR 0210544 A BR0210544 A BR 0210544A BR 0210544 A BR0210544 A BR 0210544A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- multiplex formation
- acid multiplex
- formation
- intercalators
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 239000007850 fluorescent dye Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
"FORMAçãO DE MULTIPLEX DE áCIDO NUCLéICO". A invenção refere-se a triplexes e quadruplexes, e métodos para obtenção dos mesmos; ao uso de agentes aceleradores tais como cátions para criação dos mesmos; ao uso de intercaladores fluorescentes e não-intercaladores ligados à sondas fluorescentes para detecção dos mesmos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/885,731 US6927027B2 (en) | 1999-12-21 | 2001-06-20 | Nucleic acid multiplex formation |
PCT/IB2002/001972 WO2002103051A2 (en) | 2001-06-20 | 2002-05-31 | Nucleic acid triplex and quadruplex formation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0210544A true BR0210544A (pt) | 2005-05-31 |
Family
ID=25387577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0210544-6A BR0210544A (pt) | 2001-06-20 | 2002-05-31 | Formação de multiplex de ácido nucleico |
Country Status (16)
Country | Link |
---|---|
US (1) | US6927027B2 (pt) |
EP (1) | EP1436415B1 (pt) |
JP (1) | JP2004534541A (pt) |
KR (1) | KR100699960B1 (pt) |
CN (1) | CN1533441A (pt) |
AU (1) | AU2002304318B2 (pt) |
BR (1) | BR0210544A (pt) |
CA (1) | CA2450831A1 (pt) |
CO (1) | CO5550493A2 (pt) |
HK (1) | HK1067666A1 (pt) |
IL (1) | IL159309A0 (pt) |
MX (1) | MXPA03012071A (pt) |
NZ (1) | NZ530647A (pt) |
RU (1) | RU2304168C2 (pt) |
WO (1) | WO2002103051A2 (pt) |
ZA (1) | ZA200400372B (pt) |
Families Citing this family (23)
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US6656692B2 (en) * | 1999-12-21 | 2003-12-02 | Ingeneus Corporation | Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes |
US7052844B2 (en) * | 1999-12-21 | 2006-05-30 | Ingeneus, Inc. | Purification of DS-DNA using heteropolymeric capture probes and a triplex, quadruplex or homologous duplex binding mechanism |
JP4616988B2 (ja) * | 2000-12-20 | 2011-01-19 | 株式会社アイシン・コスモス研究所 | 三本鎖dna形成技術を応用したdna多型検出方法 |
US7582429B2 (en) * | 2002-10-23 | 2009-09-01 | University Of Utah Research Foundation | Amplicon melting analysis with saturation dyes |
US20040142329A1 (en) * | 2003-01-17 | 2004-07-22 | Ingeneus Corporation | Probe conjugation to increase multiplex binding motif preference |
GB0310270D0 (en) * | 2003-05-03 | 2003-06-11 | Univ Edinburgh | Biomolecular devices |
US20050249669A1 (en) * | 2003-10-22 | 2005-11-10 | Academia Sinica | Quadruplex stabilizer |
AU2005218507A1 (en) * | 2004-02-28 | 2005-09-15 | Chang-Ning J. Wang | Nucleic acid complexes |
US9657347B2 (en) | 2004-04-20 | 2017-05-23 | University of Utah Research Foundation and BioFire Defense, LLC | Nucleic acid melting analysis with saturation dyes |
BRPI0516955A (pt) * | 2004-09-24 | 2008-09-30 | Ingeneus Inc | ensaio genÈmico |
US20090018028A1 (en) * | 2005-05-12 | 2009-01-15 | Stuart Lindsay | Self-Assembled Nucleic Acid Nanoarrays and Uses Therefor |
WO2007084380A2 (en) * | 2006-01-13 | 2007-07-26 | California Institute Of Technology | Compounds and methods for nucleic acid mismatch detection |
US7943591B2 (en) | 2007-05-11 | 2011-05-17 | Adynxx, Inc. | Gene expression and pain |
CN101587066B (zh) * | 2008-05-23 | 2011-03-30 | 中国科学院化学研究所 | 菁染料在检测g-四链体结构dna中的新用途 |
RU2429293C1 (ru) * | 2009-12-15 | 2011-09-20 | Общество С Ограниченной Ответственностью "Апто-Фарм" | Днк-аптамеры, ингибирующие тромбин, и способ стабилизации их структуры |
EP2846839B1 (en) | 2012-05-10 | 2019-02-20 | Adynxx, Inc. | Formulations for the delivery of active ingredients |
PT3180434T (pt) | 2014-08-15 | 2019-10-29 | Adynxx Inc | Chamarizes oligonucleotídicos para o tratamento da dor |
US10780051B2 (en) | 2014-10-09 | 2020-09-22 | Albert Einstein College Of Medicine | Programmed cargo release using nucleic acid-stabilized micelles |
CN105861682B (zh) * | 2016-05-05 | 2020-06-26 | 厦门多维生物医药科技有限公司 | 鸟嘌呤检测探针 |
CN110951836B (zh) * | 2019-12-03 | 2023-05-23 | 华东师范大学 | 一种基于光化学调控核酸分子链置换动力学的方法 |
CN114539422B (zh) * | 2020-11-25 | 2024-03-29 | 安升(上海)医药科技有限公司 | 核酸多聚化介导的多价蛋白药物和疫苗的构建方法及应用 |
CN113862337B (zh) * | 2021-10-15 | 2023-09-19 | 华东师范大学 | 一种基于冻融循环提高dna链置换反应速率的调控方法 |
JP7514460B2 (ja) * | 2022-03-31 | 2024-07-11 | 邦明 長峯 | ポリアミンの検出方法、ポリアミンの検出試薬及びアプタマ |
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-
2001
- 2001-06-20 US US09/885,731 patent/US6927027B2/en not_active Expired - Fee Related
-
2002
- 2002-05-31 MX MXPA03012071A patent/MXPA03012071A/es active IP Right Grant
- 2002-05-31 NZ NZ530647A patent/NZ530647A/en active IP Right Revival
- 2002-05-31 JP JP2003505372A patent/JP2004534541A/ja active Pending
- 2002-05-31 EP EP02733104A patent/EP1436415B1/en not_active Expired - Lifetime
- 2002-05-31 RU RU2004101294/13A patent/RU2304168C2/ru not_active IP Right Cessation
- 2002-05-31 CA CA002450831A patent/CA2450831A1/en not_active Abandoned
- 2002-05-31 IL IL15930902A patent/IL159309A0/xx unknown
- 2002-05-31 WO PCT/IB2002/001972 patent/WO2002103051A2/en active IP Right Grant
- 2002-05-31 KR KR1020037016650A patent/KR100699960B1/ko not_active IP Right Cessation
- 2002-05-31 AU AU2002304318A patent/AU2002304318B2/en not_active Ceased
- 2002-05-31 BR BR0210544-6A patent/BR0210544A/pt not_active IP Right Cessation
- 2002-05-31 CN CNA028124103A patent/CN1533441A/zh active Pending
-
2004
- 2004-01-19 ZA ZA200400372A patent/ZA200400372B/en unknown
- 2004-01-20 CO CO04003755A patent/CO5550493A2/es not_active Application Discontinuation
-
2005
- 2005-01-05 HK HK05100061.9A patent/HK1067666A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2002103051A2 (en) | 2002-12-27 |
MXPA03012071A (es) | 2004-06-03 |
EP1436415A2 (en) | 2004-07-14 |
EP1436415B1 (en) | 2012-08-22 |
KR20040019312A (ko) | 2004-03-05 |
RU2004101294A (ru) | 2005-02-27 |
WO2002103051A3 (en) | 2004-04-29 |
CO5550493A2 (es) | 2005-08-31 |
ZA200400372B (en) | 2004-08-23 |
AU2002304318B2 (en) | 2007-07-26 |
JP2004534541A (ja) | 2004-11-18 |
CA2450831A1 (en) | 2002-12-27 |
RU2304168C2 (ru) | 2007-08-10 |
CN1533441A (zh) | 2004-09-29 |
KR100699960B1 (ko) | 2007-03-27 |
US20030113716A1 (en) | 2003-06-19 |
IL159309A0 (en) | 2004-06-01 |
NZ530647A (pt) | 2005-12-23 |
US6927027B2 (en) | 2005-08-09 |
HK1067666A1 (en) | 2005-04-15 |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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