CO5221125A1 - TYPE 1 HYDROGEN SODIUM EXCHANGER INHIBITOR - Google Patents

TYPE 1 HYDROGEN SODIUM EXCHANGER INHIBITOR

Info

Publication number
CO5221125A1
CO5221125A1 CO01032977A CO01032977A CO5221125A1 CO 5221125 A1 CO5221125 A1 CO 5221125A1 CO 01032977 A CO01032977 A CO 01032977A CO 01032977 A CO01032977 A CO 01032977A CO 5221125 A1 CO5221125 A1 CO 5221125A1
Authority
CO
Colombia
Prior art keywords
inhibitor
type
hydrogen sodium
nhe
exchanger inhibitor
Prior art date
Application number
CO01032977A
Other languages
Spanish (es)
Inventor
George Chen Weichao
Eric David Cox
Perez Angel Guzman
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CO5221125A1 publication Critical patent/CO5221125A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Water By Ion Exchange (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Un inhibidor de NHE-1, métodos para utilizar el inhibidor de NHE-1 y composiciones farmacéuticas que contienen el inhibidor de NHE-1. El inhibidor de NHE-1 es útil para la reducción de las lesiones tisulares resultantes de la isquemia de los tejidos.<EMI FILE="01032977_1" ID="1" IMF=JPEG >An NHE-1 inhibitor, methods for using the NHE-1 inhibitor and pharmaceutical compositions containing the NHE-1 inhibitor. The NHE-1 inhibitor is useful for the reduction of tissue lesions resulting from tissue ischemia. <EMI FILE = "01032977_1" ID = "1" MFI = JPEG>

CO01032977A 2000-04-28 2001-04-27 TYPE 1 HYDROGEN SODIUM EXCHANGER INHIBITOR CO5221125A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20043200P 2000-04-28 2000-04-28

Publications (1)

Publication Number Publication Date
CO5221125A1 true CO5221125A1 (en) 2002-11-28

Family

ID=22741697

Family Applications (1)

Application Number Title Priority Date Filing Date
CO01032977A CO5221125A1 (en) 2000-04-28 2001-04-27 TYPE 1 HYDROGEN SODIUM EXCHANGER INHIBITOR

Country Status (40)

Country Link
EP (1) EP1276737A1 (en)
JP (1) JP2003531900A (en)
KR (1) KR20020093079A (en)
CN (1) CN1225466C (en)
AP (1) AP2002002651A0 (en)
AR (1) AR028375A1 (en)
AU (1) AU2001235896A1 (en)
BG (1) BG107139A (en)
BR (1) BR0110268A (en)
CA (1) CA2407535A1 (en)
CO (1) CO5221125A1 (en)
CR (1) CR6797A (en)
CZ (1) CZ20023408A3 (en)
DZ (1) DZ3310A1 (en)
EA (1) EA004882B1 (en)
EE (1) EE200200615A (en)
GT (1) GT200100064A (en)
HN (1) HN2001000042A (en)
HR (1) HRP20020851A2 (en)
HU (1) HUP0300651A2 (en)
IL (1) IL152075A0 (en)
IS (2) IS6567A (en)
MA (1) MA26897A1 (en)
MX (1) MXPA02010600A (en)
MY (1) MY133842A (en)
NO (1) NO20025132L (en)
NZ (1) NZ521348A (en)
OA (1) OA12256A (en)
PA (1) PA8513301A1 (en)
PE (1) PE20011270A1 (en)
PL (1) PL357765A1 (en)
SK (1) SK14872002A3 (en)
SV (1) SV2002000418A (en)
TN (1) TNSN01065A1 (en)
TR (1) TR200202439T2 (en)
UA (1) UA73348C2 (en)
UY (1) UY26680A1 (en)
WO (1) WO2001083470A1 (en)
YU (1) YU79602A (en)
ZA (1) ZA200208605B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2436539A1 (en) * 2001-01-31 2002-08-08 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
JP2005511787A (en) * 2001-12-19 2005-04-28 ファイザー・プロダクツ・インク Method for preparing sodium-hydrogen exchange type 1 inhibitor
EP1499317A1 (en) * 2002-05-02 2005-01-26 Pfizer Products Inc. Treatment of diabetes and diabetic complications with nhe-1 inhibitors
FR2840302B1 (en) * 2002-06-03 2004-07-16 Aventis Pharma Sa ISOINDOLONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIARY THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME
ES2220185B1 (en) * 2002-07-16 2006-04-01 Consejo Sup. De Investig. Cientificas NEW INHIBITOR PEPTIDE OF THE NA + / H + EXCHANGER (PINHE), AND ITS APPLICATIONS.
AU2004212957A1 (en) * 2003-02-14 2004-09-02 Smithkline Beecham Corporation Novel compounds
RU2518741C1 (en) * 2013-03-22 2014-06-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" MEDICATION, INHIBITING Na+/H+-EXCHANGE, AND HALOGENIDES OF 1-DIALKYLAMINOETHYL-3-[SUBSTITUTED(DISUBSTITUTED)PHENACYL]-2-AMINOBENZIMIDAZOLIUM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1454902A1 (en) * 1998-02-27 2004-09-08 Pfizer Products Inc. N- (substituted five-membered di-or triaza diunsaturated ring)carbonyl guanidine derivateives for the treatment of ischemia

Also Published As

Publication number Publication date
CN1426404A (en) 2003-06-25
ZA200208605B (en) 2003-10-24
NZ521348A (en) 2004-09-24
MXPA02010600A (en) 2003-03-10
PA8513301A1 (en) 2003-09-05
EA200201023A1 (en) 2003-02-27
IL152075A0 (en) 2003-05-29
WO2001083470A1 (en) 2001-11-08
NO20025132L (en) 2002-12-12
EE200200615A (en) 2004-04-15
TNSN01065A1 (en) 2005-11-10
CZ20023408A3 (en) 2004-01-14
UA73348C2 (en) 2005-07-15
NO20025132D0 (en) 2002-10-25
SV2002000418A (en) 2002-07-03
EA004882B1 (en) 2004-08-26
AU2001235896A1 (en) 2001-11-12
IS6567A (en) 2002-09-24
EP1276737A1 (en) 2003-01-22
IS6588A (en) 2002-10-21
HUP0300651A2 (en) 2003-07-28
DZ3310A1 (en) 2001-11-07
CA2407535A1 (en) 2001-11-08
UY26680A1 (en) 2001-12-28
BR0110268A (en) 2003-12-30
BG107139A (en) 2003-07-31
CN1225466C (en) 2005-11-02
HRP20020851A2 (en) 2005-02-28
MA26897A1 (en) 2004-12-20
YU79602A (en) 2006-05-25
SK14872002A3 (en) 2004-03-02
OA12256A (en) 2003-11-06
AP2002002651A0 (en) 2002-12-31
TR200202439T2 (en) 2003-02-21
AR028375A1 (en) 2003-05-07
KR20020093079A (en) 2002-12-12
MY133842A (en) 2007-11-30
HN2001000042A (en) 2001-07-09
PE20011270A1 (en) 2001-12-12
GT200100064A (en) 2002-03-22
JP2003531900A (en) 2003-10-28
PL357765A1 (en) 2004-07-26
CR6797A (en) 2004-05-17

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Legal Events

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