UY26680A1 - TYPE 1 SODIUM-HYDROGEN EXCHANGER INHIBITOR. - Google Patents

TYPE 1 SODIUM-HYDROGEN EXCHANGER INHIBITOR.

Info

Publication number
UY26680A1
UY26680A1 UY26680A UY26680A UY26680A1 UY 26680 A1 UY26680 A1 UY 26680A1 UY 26680 A UY26680 A UY 26680A UY 26680 A UY26680 A UY 26680A UY 26680 A1 UY26680 A1 UY 26680A1
Authority
UY
Uruguay
Prior art keywords
inhibitor
sodium
type
hydrogen exchanger
nhe
Prior art date
Application number
UY26680A
Other languages
Spanish (es)
Inventor
Weichao George Chen
Eric David Cox
Angel Guzman-Perez
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY26680A1 publication Critical patent/UY26680A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Un inhibidor de NHE-1, métodos para utilizar el inhibidor de NHE-1 y composiciones farmacéuticas que contienen el inhibidor de NHE-1. El inhibidor de NHE-1 es útil para la reducción de las lesiones tisulares resultantes de la isquemia de los tejidos.An NHE-1 inhibitor, methods of using the NHE-1 inhibitor, and pharmaceutical compositions containing the NHE-1 inhibitor. The NHE-1 inhibitor is useful for the reduction of tissue damage resulting from tissue ischemia.

UY26680A 2000-04-28 2001-04-24 TYPE 1 SODIUM-HYDROGEN EXCHANGER INHIBITOR. UY26680A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20043200P 2000-04-28 2000-04-28

Publications (1)

Publication Number Publication Date
UY26680A1 true UY26680A1 (en) 2001-12-28

Family

ID=22741697

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26680A UY26680A1 (en) 2000-04-28 2001-04-24 TYPE 1 SODIUM-HYDROGEN EXCHANGER INHIBITOR.

Country Status (40)

Country Link
EP (1) EP1276737A1 (en)
JP (1) JP2003531900A (en)
KR (1) KR20020093079A (en)
CN (1) CN1225466C (en)
AP (1) AP2002002651A0 (en)
AR (1) AR028375A1 (en)
AU (1) AU2001235896A1 (en)
BG (1) BG107139A (en)
BR (1) BR0110268A (en)
CA (1) CA2407535A1 (en)
CO (1) CO5221125A1 (en)
CR (1) CR6797A (en)
CZ (1) CZ20023408A3 (en)
DZ (1) DZ3310A1 (en)
EA (1) EA004882B1 (en)
EE (1) EE200200615A (en)
GT (1) GT200100064A (en)
HN (1) HN2001000042A (en)
HR (1) HRP20020851A2 (en)
HU (1) HUP0300651A2 (en)
IL (1) IL152075A0 (en)
IS (2) IS6567A (en)
MA (1) MA26897A1 (en)
MX (1) MXPA02010600A (en)
MY (1) MY133842A (en)
NO (1) NO20025132L (en)
NZ (1) NZ521348A (en)
OA (1) OA12256A (en)
PA (1) PA8513301A1 (en)
PE (1) PE20011270A1 (en)
PL (1) PL357765A1 (en)
SK (1) SK14872002A3 (en)
SV (1) SV2002000418A (en)
TN (1) TNSN01065A1 (en)
TR (1) TR200202439T2 (en)
UA (1) UA73348C2 (en)
UY (1) UY26680A1 (en)
WO (1) WO2001083470A1 (en)
YU (1) YU79602A (en)
ZA (1) ZA200208605B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1479737A (en) * 2001-01-31 2004-03-03 �Ʒ� Ethanolates of sodium-proton exchanger protein type-1 inhibitor
EP1456181A1 (en) * 2001-12-19 2004-09-15 Pfizer Products Inc. Methods for preparing sodium-hydrogen exchanger type-1 inhibitors
BR0309707A (en) * 2002-05-02 2005-02-09 Pfizer Prod Inc Treatment of diabetes and diabetic complications with nhe-1 inhibitors
FR2840302B1 (en) * 2002-06-03 2004-07-16 Aventis Pharma Sa ISOINDOLONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIARY THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME
ES2220185B1 (en) * 2002-07-16 2006-04-01 Consejo Sup. De Investig. Cientificas NEW INHIBITOR PEPTIDE OF THE NA + / H + EXCHANGER (PINHE), AND ITS APPLICATIONS.
PL378111A1 (en) * 2003-02-14 2006-03-06 Smithkline Beecham Corporation Novel compounds
RU2518741C1 (en) * 2013-03-22 2014-06-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" MEDICATION, INHIBITING Na+/H+-EXCHANGE, AND HALOGENIDES OF 1-DIALKYLAMINOETHYL-3-[SUBSTITUTED(DISUBSTITUTED)PHENACYL]-2-AMINOBENZIMIDAZOLIUM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1056729B1 (en) * 1998-02-27 2004-12-29 Pfizer Products Inc. N-[(substituted five-membered di- or triaza diunsaturated ring)carbonyl]guanidine derivatives for the treatment of ischemia

Also Published As

Publication number Publication date
AR028375A1 (en) 2003-05-07
ZA200208605B (en) 2003-10-24
IS6567A (en) 2002-09-24
IL152075A0 (en) 2003-05-29
PE20011270A1 (en) 2001-12-12
CZ20023408A3 (en) 2004-01-14
PA8513301A1 (en) 2003-09-05
EA004882B1 (en) 2004-08-26
CN1225466C (en) 2005-11-02
NO20025132L (en) 2002-12-12
NO20025132D0 (en) 2002-10-25
JP2003531900A (en) 2003-10-28
BG107139A (en) 2003-07-31
KR20020093079A (en) 2002-12-12
TNSN01065A1 (en) 2005-11-10
MA26897A1 (en) 2004-12-20
TR200202439T2 (en) 2003-02-21
DZ3310A1 (en) 2001-11-07
CR6797A (en) 2004-05-17
SK14872002A3 (en) 2004-03-02
AP2002002651A0 (en) 2002-12-31
HN2001000042A (en) 2001-07-09
HRP20020851A2 (en) 2005-02-28
BR0110268A (en) 2003-12-30
YU79602A (en) 2006-05-25
CN1426404A (en) 2003-06-25
AU2001235896A1 (en) 2001-11-12
GT200100064A (en) 2002-03-22
MXPA02010600A (en) 2003-03-10
MY133842A (en) 2007-11-30
WO2001083470A1 (en) 2001-11-08
EP1276737A1 (en) 2003-01-22
UA73348C2 (en) 2005-07-15
OA12256A (en) 2003-11-06
EE200200615A (en) 2004-04-15
SV2002000418A (en) 2002-07-03
EA200201023A1 (en) 2003-02-27
CA2407535A1 (en) 2001-11-08
NZ521348A (en) 2004-09-24
HUP0300651A2 (en) 2003-07-28
PL357765A1 (en) 2004-07-26
IS6588A (en) 2002-10-21
CO5221125A1 (en) 2002-11-28

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20130819