BR0110268A - Type 1 Sodium Hydrogen Inhibitors (nhe-1) - Google Patents

Type 1 Sodium Hydrogen Inhibitors (nhe-1)

Info

Publication number
BR0110268A
BR0110268A BR0110268-0A BR0110268A BR0110268A BR 0110268 A BR0110268 A BR 0110268A BR 0110268 A BR0110268 A BR 0110268A BR 0110268 A BR0110268 A BR 0110268A
Authority
BR
Brazil
Prior art keywords
nhe
type
sodium hydrogen
inhibitor
inhibitors
Prior art date
Application number
BR0110268-0A
Other languages
Portuguese (pt)
Inventor
Weichao George Chen
Eric David Cox
Angel Guzman-Perez
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0110268A publication Critical patent/BR0110268A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"INIBIDORES DE PERMUTADORES SóDIO-HIDRO-GêNIO DO TIPO 1(NHE-1)". Inibidor de NHE-1, métodos para usar o inibidor de NHE-1 e composições farmacêuticas contendo o inibidor de NHE-1. O inibidor de NHE-1 é útil para a redução do dano nos tecidos que resulta da isquemia dos tecidos."INHIBITORS OF TYPE 1 (NHE-1) SODIUM-GENIUM EXCHANGERS". NHE-1 inhibitor, methods for using the NHE-1 inhibitor and pharmaceutical compositions containing the NHE-1 inhibitor. NHE-1 inhibitor is useful for reducing tissue damage resulting from tissue ischemia.

BR0110268-0A 2000-04-28 2001-02-28 Type 1 Sodium Hydrogen Inhibitors (nhe-1) BR0110268A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20043200P 2000-04-28 2000-04-28
PCT/IB2001/000277 WO2001083470A1 (en) 2000-04-28 2001-02-28 Sodium-hydrogen exchanger type 1 inhibitor (nhe-1)

Publications (1)

Publication Number Publication Date
BR0110268A true BR0110268A (en) 2003-12-30

Family

ID=22741697

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0110268-0A BR0110268A (en) 2000-04-28 2001-02-28 Type 1 Sodium Hydrogen Inhibitors (nhe-1)

Country Status (40)

Country Link
EP (1) EP1276737A1 (en)
JP (1) JP2003531900A (en)
KR (1) KR20020093079A (en)
CN (1) CN1225466C (en)
AP (1) AP2002002651A0 (en)
AR (1) AR028375A1 (en)
AU (1) AU2001235896A1 (en)
BG (1) BG107139A (en)
BR (1) BR0110268A (en)
CA (1) CA2407535A1 (en)
CO (1) CO5221125A1 (en)
CR (1) CR6797A (en)
CZ (1) CZ20023408A3 (en)
DZ (1) DZ3310A1 (en)
EA (1) EA004882B1 (en)
EE (1) EE200200615A (en)
GT (1) GT200100064A (en)
HN (1) HN2001000042A (en)
HR (1) HRP20020851A2 (en)
HU (1) HUP0300651A2 (en)
IL (1) IL152075A0 (en)
IS (2) IS6567A (en)
MA (1) MA26897A1 (en)
MX (1) MXPA02010600A (en)
MY (1) MY133842A (en)
NO (1) NO20025132L (en)
NZ (1) NZ521348A (en)
OA (1) OA12256A (en)
PA (1) PA8513301A1 (en)
PE (1) PE20011270A1 (en)
PL (1) PL357765A1 (en)
SK (1) SK14872002A3 (en)
SV (1) SV2002000418A (en)
TN (1) TNSN01065A1 (en)
TR (1) TR200202439T2 (en)
UA (1) UA73348C2 (en)
UY (1) UY26680A1 (en)
WO (1) WO2001083470A1 (en)
YU (1) YU79602A (en)
ZA (1) ZA200208605B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002060892A1 (en) * 2001-01-31 2002-08-08 Pfizer Products Inc. Ethanolates of sodium-hydrogen exchanger type-1 inhibitor
CA2469305A1 (en) * 2001-12-19 2003-06-26 Frank Robert Busch Methods for preparing sodium-hydrogen exchanger type-1 inhibitors
CA2483927A1 (en) * 2002-05-02 2003-11-13 Pfizer Products Inc. Treatment of diabetes and diabetic complications with nhe-1 inhibitors
FR2840302B1 (en) * 2002-06-03 2004-07-16 Aventis Pharma Sa ISOINDOLONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIARY THEREOF AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME
ES2220185B1 (en) * 2002-07-16 2006-04-01 Consejo Sup. De Investig. Cientificas NEW INHIBITOR PEPTIDE OF THE NA + / H + EXCHANGER (PINHE), AND ITS APPLICATIONS.
EP1596860A4 (en) * 2003-02-14 2009-05-27 Smithkline Beecham Corp Novel compounds
RU2518741C1 (en) * 2013-03-22 2014-06-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" MEDICATION, INHIBITING Na+/H+-EXCHANGE, AND HALOGENIDES OF 1-DIALKYLAMINOETHYL-3-[SUBSTITUTED(DISUBSTITUTED)PHENACYL]-2-AMINOBENZIMIDAZOLIUM

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU739403B2 (en) * 1998-02-27 2001-10-11 Pfizer Products Inc. N-((substituted five-membered di- or triaza diunsaturated ring)carbonyl) guanidine derivatives for the treatment of ischemia

Also Published As

Publication number Publication date
UY26680A1 (en) 2001-12-28
OA12256A (en) 2003-11-06
CR6797A (en) 2004-05-17
MXPA02010600A (en) 2003-03-10
IS6588A (en) 2002-10-21
TNSN01065A1 (en) 2005-11-10
DZ3310A1 (en) 2001-11-07
IS6567A (en) 2002-09-24
JP2003531900A (en) 2003-10-28
CO5221125A1 (en) 2002-11-28
PL357765A1 (en) 2004-07-26
IL152075A0 (en) 2003-05-29
TR200202439T2 (en) 2003-02-21
EP1276737A1 (en) 2003-01-22
NO20025132D0 (en) 2002-10-25
PE20011270A1 (en) 2001-12-12
MA26897A1 (en) 2004-12-20
YU79602A (en) 2006-05-25
NZ521348A (en) 2004-09-24
UA73348C2 (en) 2005-07-15
NO20025132L (en) 2002-12-12
CN1426404A (en) 2003-06-25
KR20020093079A (en) 2002-12-12
AU2001235896A1 (en) 2001-11-12
AP2002002651A0 (en) 2002-12-31
GT200100064A (en) 2002-03-22
HN2001000042A (en) 2001-07-09
EE200200615A (en) 2004-04-15
HUP0300651A2 (en) 2003-07-28
CA2407535A1 (en) 2001-11-08
HRP20020851A2 (en) 2005-02-28
BG107139A (en) 2003-07-31
ZA200208605B (en) 2003-10-24
EA200201023A1 (en) 2003-02-27
SV2002000418A (en) 2002-07-03
WO2001083470A1 (en) 2001-11-08
CN1225466C (en) 2005-11-02
SK14872002A3 (en) 2004-03-02
PA8513301A1 (en) 2003-09-05
EA004882B1 (en) 2004-08-26
AR028375A1 (en) 2003-05-07
MY133842A (en) 2007-11-30
CZ20023408A3 (en) 2004-01-14

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A , 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO DA RPI 2016 DE 25/08/2009.