CO4940506A1 - Derivados de la 9-oxima eritromicina - Google Patents

Derivados de la 9-oxima eritromicina

Info

Publication number
CO4940506A1
CO4940506A1 CO98033538A CO98033538A CO4940506A1 CO 4940506 A1 CO4940506 A1 CO 4940506A1 CO 98033538 A CO98033538 A CO 98033538A CO 98033538 A CO98033538 A CO 98033538A CO 4940506 A1 CO4940506 A1 CO 4940506A1
Authority
CO
Colombia
Prior art keywords
alkyl
integer
optionally substituted
formula xvi
ring
Prior art date
Application number
CO98033538A
Other languages
English (en)
Spanish (es)
Inventor
Wu Tong-Jin
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of CO4940506A1 publication Critical patent/CO4940506A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
CO98033538A 1997-06-11 1998-06-11 Derivados de la 9-oxima eritromicina CO4940506A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4934997P 1997-06-11 1997-06-11

Publications (1)

Publication Number Publication Date
CO4940506A1 true CO4940506A1 (es) 2000-07-24

Family

ID=21959341

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98033538A CO4940506A1 (es) 1997-06-11 1998-06-11 Derivados de la 9-oxima eritromicina

Country Status (31)

Country Link
EP (1) EP0988308A1 (no)
JP (1) JP2000513026A (no)
KR (1) KR20010013660A (no)
CN (1) CN1259135A (no)
AP (1) AP9801253A0 (no)
AR (1) AR012244A1 (no)
AU (1) AU7226798A (no)
BG (1) BG103947A (no)
BR (1) BR9810021A (no)
CA (1) CA2293335A1 (no)
CO (1) CO4940506A1 (no)
CZ (1) CZ9904388A3 (no)
EA (1) EA199901016A1 (no)
GT (1) GT199800074A (no)
HN (1) HN1998000073A (no)
HR (1) HRP980316A2 (no)
HU (1) HUP0002252A3 (no)
ID (1) ID24529A (no)
IL (1) IL132767A0 (no)
IS (1) IS5251A (no)
MA (1) MA26505A1 (no)
NO (1) NO996108L (no)
OA (1) OA11225A (no)
PA (1) PA8451801A1 (no)
PE (1) PE79899A1 (no)
PL (1) PL337606A1 (no)
TN (1) TNSN98083A1 (no)
TR (1) TR199902995T2 (no)
TW (1) TW448174B (no)
WO (1) WO1998056800A1 (no)
ZA (1) ZA985018B (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
ATE298761T1 (de) 1998-09-22 2005-07-15 Pfizer Prod Inc Carbamat- und carbazatketolidantibiotika
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
US6258785B1 (en) 1998-12-02 2001-07-10 Pfizer Inc. Crystalline 9-E-(O-methyl)oxime of 11, 12-dideoxy-3-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyloxy)-6-O-methyl-12,11-(iminocarbonyl-(2-(3-(4-(3-pyridinyl)1H-imadazol-1-yl)propyl)hydrazono))-3-oxoerythromycin
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
US6284732B1 (en) * 1998-12-18 2001-09-04 Bio-Rad Laboratories, Inc. Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
ATE340183T1 (de) * 1999-04-16 2006-10-15 Kosan Biosciences Inc Antiinfektiöse makrolidderivate
HUP0201516A3 (en) 1999-05-24 2003-03-28 Pfizer Prod Inc 13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
WO2000075156A1 (en) * 1999-06-07 2000-12-14 Abbott Laboratories 6-o-carbamate ketolide derivatives
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
EP1439186A3 (en) * 1999-12-29 2004-11-03 Pfizer Products Inc. Intermediates for novel antibacterial and prokinetic macrolides
EP1114826A3 (en) * 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6403776B1 (en) 2000-07-05 2002-06-11 Pfizer Inc. Synthesis of carbamate ketolide antibiotics
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
EP1638549A4 (en) * 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc NEW ANTIBACTERIAL AGENTS
EP1723159B1 (en) 2004-02-27 2019-06-12 Melinta Therapeutics, Inc. Macrocyclic compounds and methods of making and using the same
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
US8796232B2 (en) 2008-10-24 2014-08-05 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
CN102146085B (zh) * 2010-02-09 2014-03-26 北京理工大学 一种9-肟醚酮内酯衍生物、制备方法及其药物组合物
CN103080122A (zh) 2010-03-22 2013-05-01 森普拉制药公司 大环内脂的结晶形式及其用途
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
CN104470527B (zh) 2012-03-27 2019-05-28 森普拉制药公司 用于施用大环内酯抗生素的肠胃外制剂
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
TW448174B (en) 2001-08-01
KR20010013660A (ko) 2001-02-26
HN1998000073A (es) 1999-01-08
BG103947A (en) 2000-07-31
TNSN98083A1 (fr) 2005-03-15
BR9810021A (pt) 2000-09-19
NO996108L (no) 2000-02-10
PE79899A1 (es) 1999-08-25
AP9801253A0 (en) 1999-12-04
HUP0002252A3 (en) 2002-01-28
AR012244A1 (es) 2000-09-27
NO996108D0 (no) 1999-12-10
CA2293335A1 (en) 1998-12-17
CZ9904388A3 (cs) 2002-10-16
GT199800074A (es) 1999-11-27
EA199901016A1 (ru) 2000-06-26
ID24529A (id) 2000-07-20
IS5251A (is) 1999-11-16
EP0988308A1 (en) 2000-03-29
AU7226798A (en) 1998-12-30
HRP980316A2 (en) 1999-04-30
TR199902995T2 (xx) 2000-02-21
PA8451801A1 (es) 2000-05-24
PL337606A1 (en) 2000-08-28
HUP0002252A2 (hu) 2000-12-28
ZA985018B (en) 1999-12-10
IL132767A0 (en) 2001-03-19
OA11225A (en) 2003-07-17
JP2000513026A (ja) 2000-10-03
WO1998056800A1 (en) 1998-12-17
MA26505A1 (fr) 2004-12-20
CN1259135A (zh) 2000-07-05

Similar Documents

Publication Publication Date Title
CO4940506A1 (es) Derivados de la 9-oxima eritromicina
AR035548A1 (es) Compuestos organicos
ECSP034611A (es) Aminotiazoles y su uso como antagonistas del receptor de adenosina
PE20040373A1 (es) Composiciones herbicidas que comprenden derivados de isoxazolina
ECSP034475A (es) Derivados de 4-fenil-piridin como antagonistas del receptor de neuroquinina-1
AR046200A1 (es) Derivados de pirazina y su uso farmaceutico. procesos de preparacion y composiciones farmaceuticas
NO20022317D0 (no) Trifenylalkylen-derivater og deres anvendelse som selektive östrogen-reseptor-modulater
AR009413A1 (es) Un compuesto, el cual es un derivado de distamicina benzoheterociclico, su utilizacion, un procedimiento para producirlo y una composicionfarmaceutica que lo comprende
ID21568A (id) Penggunaan baru untuk turunan 1,3-propanadiol
CO4650117A1 (es) Derivados de bencilsulfuro y proceso para su produccion .
AR015964A1 (es) Compuestos de isoquinolina, su uso, procedimiento para tratar una afeccion, procedimiento de preparacion del compuesto, composicion farmaceutica que locontiene y compuesto util en dicho procedimiento
AR006189A1 (es) Aminoalquil-eteres y acilaminoalquil-eteres, procedimiento para su preparacion y su utilizacion como antagonistas de receptores de bradiquinina
PE20010750A1 (es) Derivados de espiro [2h-1-benzopiran-2,4`-piperidina]
EA199800987A1 (ru) Бензоксазиноновые антагонисты рецептора допамина d4
MX9301045A (es) Procedimiento para preparar antagonistas receptores de fibrinogeno.
TW200517387A (en) Compounds exhibiting thrombopoietin receptor agonism
CO5200762A1 (es) Preparacion de piperidin-4-onas sustituidas
DK1381370T3 (da) N-Biphenylcarbonyl- og N-phenylpyridylcarbonyl-substituerede bi- og tricykliske azepiner og diazepiner som vasopressin-agonister
AR036734A1 (es) Derivados de 8-amino-[1,2,4]triazolo[1,5-a]piridina-6-carboxilico
ATE168686T1 (de) N,n'-disubstituierte amidderivate
PE20040943A1 (es) 2-AMINOIMIDAZOLES SUSTITUIDOS COMO INHIBIDORES DEL INTERCAMBIADOR Na/H SUBTIPO 3 (NHE 3)
ES447751A1 (es) Procedimiento para preparar derivados de imidazolilquinazo- lina.
YU46941B (sh) Aruloksi-ariltio-, heteroariloksi-, heteroariltio- alkenilenski derivati amina i postupak za njihovo dobijanje
ES2170802T3 (es) Carboxamidas biciclicas como ligandos de los receptores 5-ht1a.
AR008920A1 (es) Proceso para la preparacion de los derivados de 2-amino-2-imidaxolina, guanidina, y 2-amino-3,4,5,6-tetrahidropiridimina