CO4410197A1 - Forma cristalina de un derivado de dihidro-2, 3-benzodiacepina - Google Patents
Forma cristalina de un derivado de dihidro-2, 3-benzodiacepinaInfo
- Publication number
- CO4410197A1 CO4410197A1 CO95030584A CO95030584A CO4410197A1 CO 4410197 A1 CO4410197 A1 CO 4410197A1 CO 95030584 A CO95030584 A CO 95030584A CO 95030584 A CO95030584 A CO 95030584A CO 4410197 A1 CO4410197 A1 CO 4410197A1
- Authority
- CO
- Colombia
- Prior art keywords
- aminophenyl
- formula
- acetyl
- methyl
- compound
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 6
- UKJLNMAFNRKWGR-UHFFFAOYSA-N cyclohexatrienamine Chemical class NC1=CC=C=C[CH]1 UKJLNMAFNRKWGR-UHFFFAOYSA-N 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical group NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003245 coal Substances 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- WFIZEGIEIOHZCP-UHFFFAOYSA-M potassium formate Chemical compound [K+].[O-]C=O WFIZEGIEIOHZCP-UHFFFAOYSA-M 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 235000011121 sodium hydroxide Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29864594A | 1994-08-31 | 1994-08-31 | |
| US08/412,242 US6329364B1 (en) | 1994-08-31 | 1995-03-28 | Crystalline form of dihydro-2,3-benzodiazepine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4410197A1 true CO4410197A1 (es) | 1997-01-09 |
Family
ID=23151416
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO95030584A CO4410197A1 (es) | 1994-08-31 | 1995-07-12 | Forma cristalina de un derivado de dihidro-2, 3-benzodiacepina |
| CO95030585A CO4410198A1 (es) | 1994-08-31 | 1995-07-12 | Forma fisica de un derivado de dihidro-2,3-benzodiacepina |
| CO95030588A CO4410199A1 (es) | 1994-08-31 | 1995-07-12 | Procedimiento estereoselectivo para producir derivados de dihidro-2,3-benzodiacepina |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO95030585A CO4410198A1 (es) | 1994-08-31 | 1995-07-12 | Forma fisica de un derivado de dihidro-2,3-benzodiacepina |
| CO95030588A CO4410199A1 (es) | 1994-08-31 | 1995-07-12 | Procedimiento estereoselectivo para producir derivados de dihidro-2,3-benzodiacepina |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US6329364B1 (forum.php) |
| KR (2) | KR100386933B1 (forum.php) |
| CO (3) | CO4410197A1 (forum.php) |
| HU (1) | HU223846B1 (forum.php) |
| MY (2) | MY117754A (forum.php) |
| NZ (1) | NZ272896A (forum.php) |
| PE (3) | PE32996A1 (forum.php) |
| RU (1) | RU2142465C1 (forum.php) |
| SI (2) | SI0699677T1 (forum.php) |
| TW (3) | TW393485B (forum.php) |
| UA (3) | UA44698C2 (forum.php) |
| YU (3) | YU49288B (forum.php) |
| ZA (3) | ZA957278B (forum.php) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0651746B1 (en) * | 1992-07-24 | 2002-03-27 | The Regents of the University of California | Drugs that enhance synaptic responses mediated by ampa receptors |
| KR100478129B1 (ko) * | 1996-12-20 | 2005-12-26 | 주식회사 효성 | 투습방수직물의제조방법 |
| US20030109525A1 (en) * | 2001-07-10 | 2003-06-12 | Pharmacia & Upjohn Company | Crystalline thiazine oxazolidinones |
| JP4159988B2 (ja) * | 2001-08-15 | 2008-10-01 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | Ｎ−［２−（ジエチルアミノ）エチル］−５−［（５−フルオロ−１，２−ジヒドロ−２−オキソ−３ｈ−インドール−３−イリデン）メチル］−２，４−ジメチル−１ｈ−ピロール−３−カルボキシアミドのリンゴ酸塩を含む結晶、その製法およびその組成物 |
| KR20040032188A (ko) * | 2002-10-01 | 2004-04-17 | 기아자동차주식회사 | 개량형 아웃사이드 미러 |
| EP1979308A1 (en) * | 2005-12-30 | 2008-10-15 | EGIS Gyógyszergyár Nyrt | Optical isomers of dihydro-2,3-benzodiazepines and their stereoselective synthesis |
| US20160137573A1 (en) * | 2014-11-14 | 2016-05-19 | Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, | Methods and catalyst systems for carbon dioxide conversion |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3748342A (en) * | 1971-05-06 | 1973-07-24 | Sandoz Ag | Intermediates for preparing quinazolinones |
| US3794642A (en) * | 1973-01-15 | 1974-02-26 | Lilly Co Eli | Oxidation of substituted methanes to the corresponding substituted methanols |
| US4560510A (en) * | 1984-04-06 | 1985-12-24 | A. H. Robins Company, Incorporated | Process and intermediates for the preparation of aryl substituted pyrido[1,4]benzodiazepines |
| HU191698B (en) * | 1984-07-27 | 1987-03-30 | Gyogyszerkutato Intezet | Process for producing new 1-aryl-5h-2beta-benzodiazepines |
| HU198494B (en) * | 1986-08-15 | 1989-10-30 | Gyogyszerkutato Intezet | Process for producing new 3,4-dihydro-5h-2,3-benzodiazepine derivative and acid addition salts thereof, as well as pharmaceutical compositions comprising same |
| WO1989007648A1 (en) * | 1988-02-12 | 1989-08-24 | Daicel Chemical Industries, Ltd. | Process for preparing optically active 2-hydroxy acid derivatives |
| HU206719B (en) * | 1990-12-21 | 1992-12-28 | Gyogyszerkutato Intezet | Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them |
| HU219778B (hu) | 1990-12-21 | 2001-07-30 | Gyógyszerkutató Intézet Közös Vállalat | Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények |
| HU219777B (hu) * | 1993-07-02 | 2001-07-30 | Gyógyszerkutató Intézet Kft. | Optikailag aktív 1-(4-nitro-fenil)-4-metil-7,8-metiléndioxi-3,4-dihidro-5H-2,3-benzodiazepin és eljárás előállítására |
-
1995
- 1995-03-28 US US08/412,242 patent/US6329364B1/en not_active Expired - Fee Related
- 1995-03-28 US US08/413,036 patent/US5665878A/en not_active Expired - Lifetime
- 1995-03-28 US US08/413,024 patent/US6288057B1/en not_active Expired - Fee Related
- 1995-07-12 TW TW084107231A patent/TW393485B/zh not_active IP Right Cessation
- 1995-07-12 PE PE1995273614A patent/PE32996A1/es not_active Application Discontinuation
- 1995-07-12 CO CO95030584A patent/CO4410197A1/es unknown
- 1995-07-12 PE PE1995273616A patent/PE28196A1/es not_active Application Discontinuation
- 1995-07-12 TW TW084107230A patent/TW390881B/zh not_active IP Right Cessation
- 1995-07-12 CO CO95030585A patent/CO4410198A1/es unknown
- 1995-07-12 CO CO95030588A patent/CO4410199A1/es unknown
- 1995-07-12 TW TW084107229A patent/TW372965B/zh not_active IP Right Cessation
- 1995-07-12 PE PE1995273615A patent/PE32896A1/es not_active Application Discontinuation
- 1995-08-29 MY MYPI95002564A patent/MY117754A/en unknown
- 1995-08-30 ZA ZA957278A patent/ZA957278B/xx unknown
- 1995-08-30 YU YU57695A patent/YU49288B/sh unknown
- 1995-08-30 ZA ZA957279A patent/ZA957279B/xx unknown
- 1995-08-30 YU YU57895A patent/YU49349B/sh unknown
- 1995-08-30 ZA ZA957280A patent/ZA957280B/xx unknown
- 1995-08-30 UA UA95083977A patent/UA44698C2/uk unknown
- 1995-08-30 UA UA95083975A patent/UA45309C2/uk unknown
- 1995-08-30 KR KR1019950027527A patent/KR100386933B1/ko not_active Expired - Fee Related
- 1995-08-30 HU HU0003319A patent/HU223846B1/hu not_active IP Right Cessation
- 1995-08-30 SI SI9530640T patent/SI0699677T1/xx unknown
- 1995-08-30 KR KR1019950027528A patent/KR100386934B1/ko not_active Expired - Fee Related
- 1995-08-30 RU RU95114550A patent/RU2142465C1/ru not_active IP Right Cessation
- 1995-08-30 UA UA95083976A patent/UA41354C2/uk unknown
- 1995-08-30 YU YU57795A patent/YU49289B/sh unknown
- 1995-08-30 SI SI9530701T patent/SI0699678T1/xx unknown
- 1995-08-30 MY MYPI95002583A patent/MY118394A/en unknown
- 1995-08-30 NZ NZ272896A patent/NZ272896A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| YU57695A (sh) | 1998-07-10 |
| UA41354C2 (uk) | 2001-09-17 |
| MY118394A (en) | 2004-10-30 |
| HU223846B1 (hu) | 2005-02-28 |
| SI0699678T1 (en) | 2004-06-30 |
| ZA957279B (en) | 1997-02-28 |
| HU0003319D0 (forum.php) | 1995-08-30 |
| PE28196A1 (es) | 1996-07-04 |
| UA45309C2 (uk) | 2002-04-15 |
| CO4410199A1 (es) | 1997-01-09 |
| ZA957278B (en) | 1997-02-28 |
| YU49349B (sh) | 2005-07-19 |
| TW393485B (en) | 2000-06-11 |
| KR960007596A (ko) | 1996-03-22 |
| NZ272896A (en) | 1997-03-24 |
| YU49289B (sh) | 2005-03-15 |
| PE32996A1 (es) | 1996-08-10 |
| TW372965B (en) | 1999-11-01 |
| UA44698C2 (uk) | 2002-03-15 |
| ZA957280B (en) | 1997-02-28 |
| US6288057B1 (en) | 2001-09-11 |
| KR960007597A (ko) | 1996-03-22 |
| YU49288B (sh) | 2005-03-15 |
| KR100386934B1 (ko) | 2003-10-04 |
| YU57795A (sh) | 1998-07-10 |
| MY117754A (en) | 2004-08-30 |
| TW390881B (en) | 2000-05-21 |
| CO4410198A1 (es) | 1997-01-09 |
| RU2142465C1 (ru) | 1999-12-10 |
| SI0699677T1 (en) | 2003-06-30 |
| PE32896A1 (es) | 1996-08-07 |
| YU57895A (sh) | 1998-07-10 |
| US6329364B1 (en) | 2001-12-11 |
| US5665878A (en) | 1997-09-09 |
| KR100386933B1 (ko) | 2003-09-19 |
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