CO2024015189A2 - Receptor multipartito y complejos de señalización - Google Patents

Receptor multipartito y complejos de señalización

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Publication number
CO2024015189A2
CO2024015189A2 CONC2024/0015189A CO2024015189A CO2024015189A2 CO 2024015189 A2 CO2024015189 A2 CO 2024015189A2 CO 2024015189 A CO2024015189 A CO 2024015189A CO 2024015189 A2 CO2024015189 A2 CO 2024015189A2
Authority
CO
Colombia
Prior art keywords
signaling complexes
multipartite
receptor
disease
recruiting
Prior art date
Application number
CONC2024/0015189A
Other languages
English (en)
Spanish (es)
Inventor
Jordan Jarjour
Jardin Alexandra Leleux
Mark Pogson
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of CO2024015189A2 publication Critical patent/CO2024015189A2/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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CONC2024/0015189A 2022-04-08 2024-11-06 Receptor multipartito y complejos de señalización CO2024015189A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263329003P 2022-04-08 2022-04-08
PCT/US2023/065552 WO2023196996A2 (en) 2022-04-08 2023-04-07 Multipartite receptor and signaling complexes

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CO2024015189A2 true CO2024015189A2 (es) 2024-12-30

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CONC2024/0015183A CO2024015183A2 (es) 2022-04-08 2024-11-06 Receptor multipartito y complejos de señalización

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US (2) US20250312451A1 (https=)
EP (2) EP4504248A2 (https=)
JP (2) JP2025513801A (https=)
KR (2) KR20250008810A (https=)
CN (2) CN119546328A (https=)
AU (2) AU2023251117A1 (https=)
CA (2) CA3255502A1 (https=)
CL (2) CL2024003025A1 (https=)
CO (2) CO2024015189A2 (https=)
IL (2) IL316032A (https=)
MX (2) MX2024012449A (https=)
WO (2) WO2023196997A2 (https=)

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