CO2023010206A2 - Conjugados de anticuerpo dirigido a b7-h4 y fármaco, y métodos de uso de los mismos - Google Patents

Conjugados de anticuerpo dirigido a b7-h4 y fármaco, y métodos de uso de los mismos

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Publication number
CO2023010206A2
CO2023010206A2 CONC2023/0010206A CO2023010206A CO2023010206A2 CO 2023010206 A2 CO2023010206 A2 CO 2023010206A2 CO 2023010206 A CO2023010206 A CO 2023010206A CO 2023010206 A2 CO2023010206 A2 CO 2023010206A2
Authority
CO
Colombia
Prior art keywords
methods
drug conjugates
targeted antibody
conjugates
antibody
Prior art date
Application number
CONC2023/0010206A
Other languages
English (en)
Spanish (es)
Inventor
Marc I Damelin
Timothy B Lowinger
Dorin Toader
Chen-Ni Chin
Original Assignee
Mersana Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mersana Therapeutics Inc filed Critical Mersana Therapeutics Inc
Publication of CO2023010206A2 publication Critical patent/CO2023010206A2/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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