CO2022004470A2 - Vectores de herpesvirus de los pavos recombinante que expresan antígenos de patógenos aviares y usos de estos - Google Patents
Vectores de herpesvirus de los pavos recombinante que expresan antígenos de patógenos aviares y usos de estosInfo
- Publication number
- CO2022004470A2 CO2022004470A2 CONC2022/0004470A CO2022004470A CO2022004470A2 CO 2022004470 A2 CO2022004470 A2 CO 2022004470A2 CO 2022004470 A CO2022004470 A CO 2022004470A CO 2022004470 A2 CO2022004470 A2 CO 2022004470A2
- Authority
- CO
- Colombia
- Prior art keywords
- turkeys
- vectors expressing
- recombinant herpesvirus
- pathogen antigens
- avian pathogen
- Prior art date
Links
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- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/17—Newcastle disease virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
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- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- C12N2710/00011—Details
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16041—Use of virus, viral particle or viral elements as a vector
- C12N2710/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16321—Viruses as such, e.g. new isolates, mutants or their genomic sequences
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16311—Mardivirus, e.g. Gallid herpesvirus 2, Marek-like viruses, turkey HV
- C12N2710/16341—Use of virus, viral particle or viral elements as a vector
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- C12N2720/00011—Details
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- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
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- Health & Medical Sciences (AREA)
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- Virology (AREA)
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Abstract
La invención se refiere a vectores virales recombinantes para la inserción y expresión de genes extraños para su uso en inmunizaciones seguras con el fin de brindar protección contra diversos patógenos. La invención también se refiere a vacunas o composiciones multivalentes que comprenden uno o más vectores virales recombinantes con el fin de brindar protección contra diversos patógenos. La presente invención se refiere a métodos de elaboración y uso de dichos vectores virales recombinantes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962898651P | 2019-09-11 | 2019-09-11 | |
PCT/US2020/050164 WO2021050701A1 (en) | 2019-09-11 | 2020-09-10 | Recombinant herpesvirus of turkey vectors expressing antigens of avian pathogens and uses thereof |
Publications (1)
Publication Number | Publication Date |
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CO2022004470A2 true CO2022004470A2 (es) | 2022-04-29 |
Family
ID=72644953
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CONC2022/0004470A CO2022004470A2 (es) | 2019-09-11 | 2022-04-07 | Vectores de herpesvirus de los pavos recombinante que expresan antígenos de patógenos aviares y usos de estos |
Country Status (12)
Country | Link |
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US (2) | US11464849B2 (es) |
EP (1) | EP4028510A1 (es) |
JP (1) | JP2022547975A (es) |
KR (1) | KR20220056241A (es) |
CN (1) | CN114616325A (es) |
AU (1) | AU2020347180A1 (es) |
BR (1) | BR112022004488A2 (es) |
CA (1) | CA3153379A1 (es) |
CO (1) | CO2022004470A2 (es) |
IL (1) | IL290899A (es) |
MX (1) | MX2022002994A (es) |
WO (1) | WO2021050701A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021050701A1 (en) * | 2019-09-11 | 2021-03-18 | Zoetis Services Llc | Recombinant herpesvirus of turkey vectors expressing antigens of avian pathogens and uses thereof |
CN112048484A (zh) * | 2020-07-27 | 2020-12-08 | 华南农业大学 | 一株表达传染性法氏囊强毒株vp2蛋白的基因ⅶ型新城疫重组病毒和疫苗 |
CN116042709A (zh) * | 2022-09-23 | 2023-05-02 | 广西大学 | 一种共表达马立克病病毒糖蛋白gC和gD的DNA疫苗构建方法 |
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US5965138A (en) | 1985-09-06 | 1999-10-12 | Syntro Corporation | Recombinant chimeric virus and uses thereof |
US5834305A (en) | 1985-09-06 | 1998-11-10 | Syntro Corporation | Attenuated herpesvirus, herpesvirus which include foreign DNA encoding an amino acid sequence and vaccines containing same |
US6121043A (en) | 1985-09-06 | 2000-09-19 | Syntro Corporation | Recombinant herpesvirus of turkeys comprising a foreign DNA inserted into a non-essential region of the herpesvirus of turkeys genome |
WO1987004463A1 (en) | 1986-01-27 | 1987-07-30 | Syntro Corporation | Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same |
JP2779447B2 (ja) | 1988-03-20 | 1998-07-23 | 財団法人阪大微生物病研究会 | 弱毒マレック病ウイルス・ベクターを用いる組換え遺伝子作成法、及び該ウイルスの組換え体 |
ATE150976T1 (de) | 1989-10-02 | 1997-04-15 | Univ Arkansas | Impfstoff-konjugate zur behandlung von vogelkrankheiten |
EP0431668B1 (en) * | 1989-12-04 | 1995-02-15 | Akzo Nobel N.V. | Recombinant herpesvirus of turkeys and live vector vaccines derived thereof |
US5231023A (en) | 1990-07-30 | 1993-07-27 | Akzo N.V. | Recombinant Marek's disease virus |
US5350576A (en) | 1991-09-13 | 1994-09-27 | Mycogen Corporation | Bacillus thuringiensis isolates for controlling acarides |
US6183753B1 (en) | 1994-08-09 | 2001-02-06 | Schering-Plough Veterinary Corp. | Recombinant chimeric virus and uses thereof |
US5853733A (en) | 1993-02-26 | 1998-12-29 | Syntro Corporation | Recombinant herpesvirus of turkeys and uses thereof |
FR2728795B1 (fr) | 1994-12-30 | 1997-03-21 | Rhone Merieux | Vaccin vivant recombinant aviaire, utilisant comme vecteur un virus herpes aviaire |
DE69632235T2 (de) * | 1995-10-18 | 2004-08-26 | Akzo Nobel N.V. | Newcastle-Krankheitsvirus-Kombinationsimpfstoff |
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2020
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- 2020-09-10 US US17/017,342 patent/US11464849B2/en active Active
- 2020-09-10 MX MX2022002994A patent/MX2022002994A/es unknown
- 2020-09-10 KR KR1020227011729A patent/KR20220056241A/ko not_active Application Discontinuation
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KR20220056241A (ko) | 2022-05-04 |
US20220409718A1 (en) | 2022-12-29 |
BR112022004488A2 (pt) | 2022-05-31 |
US11464849B2 (en) | 2022-10-11 |
CN114616325A (zh) | 2022-06-10 |
US20210196811A1 (en) | 2021-07-01 |
WO2021050701A9 (en) | 2021-05-06 |
CA3153379A1 (en) | 2021-03-18 |
US11883481B2 (en) | 2024-01-30 |
EP4028510A1 (en) | 2022-07-20 |
IL290899A (en) | 2022-04-01 |
MX2022002994A (es) | 2022-06-14 |
JP2022547975A (ja) | 2022-11-16 |
AU2020347180A1 (en) | 2022-03-24 |
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