BR112018075585A2 - spv recombinante multivalente - Google Patents

spv recombinante multivalente

Info

Publication number
BR112018075585A2
BR112018075585A2 BR112018075585-0A BR112018075585A BR112018075585A2 BR 112018075585 A2 BR112018075585 A2 BR 112018075585A2 BR 112018075585 A BR112018075585 A BR 112018075585A BR 112018075585 A2 BR112018075585 A2 BR 112018075585A2
Authority
BR
Brazil
Prior art keywords
recombinant spv
defective
multivalent recombinant
recombinant swinepox
il18bp
Prior art date
Application number
BR112018075585-0A
Other languages
English (en)
Inventor
Sato Takanori
Saitoh Shuji
Komiya Yasutoshi
Original Assignee
Ceva Sante Animale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceva Sante Animale filed Critical Ceva Sante Animale
Publication of BR112018075585A2 publication Critical patent/BR112018075585A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

a presente invenção se refere a vírus da varíola suína recombinantes inovadores e seu uso em composições de vacina. os vírus da varíola suína recombinantes da invenção são duplamente defectivos para os genes il18bp e tk, e compreendem pelo menos um gene exógeno clonado na sequência de gene tk defectivo. a invenção é particularmente adequada para produzir vacinas para suínos, particularmente para vacinar suínos contra infecção por pcv2.
BR112018075585-0A 2016-06-10 2017-06-09 spv recombinante multivalente BR112018075585A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16305697.1 2016-06-10
EP16305697.1A EP3254692A1 (en) 2016-06-10 2016-06-10 Multivalent recombinant spv
PCT/EP2017/064183 WO2017212048A1 (en) 2016-06-10 2017-06-09 Multivalent recombinant spv

Publications (1)

Publication Number Publication Date
BR112018075585A2 true BR112018075585A2 (pt) 2019-03-19

Family

ID=56943447

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018075585-0A BR112018075585A2 (pt) 2016-06-10 2017-06-09 spv recombinante multivalente

Country Status (9)

Country Link
US (1) US11020472B2 (pt)
EP (1) EP3254692A1 (pt)
CN (1) CN109562157B (pt)
BR (1) BR112018075585A2 (pt)
CA (1) CA3027196A1 (pt)
MX (1) MX2018015341A (pt)
PH (1) PH12018502576A1 (pt)
RU (1) RU2766008C2 (pt)
WO (1) WO2017212048A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3720485A1 (en) * 2017-12-08 2020-10-14 Ceva Sante Animale Recombinant swinepox virus and vaccines
WO2019110820A1 (en) * 2017-12-08 2019-06-13 Ceva Sante Animale Recombinant swinepox virus encoding a pcv3 antigen
CN113373119A (zh) * 2021-06-02 2021-09-10 江西农业大学 一种表达非洲猪瘟病毒三基因缺失重组伪狂犬病毒毒株、构建方法及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2531729B2 (ja) 1987-03-27 1996-09-04 日本ゼオン株式会社 組み換えアビポックスウイルス
US5651972A (en) 1989-04-21 1997-07-29 University Of Florida Research Foundation, Inc. Use of recombinant swine poxvirus as a live vaccine vector
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
EP1816200B1 (en) 1997-12-11 2016-03-09 Merial Postweaning multisystemic wasting syndrome virus for pigs
PT1037909E (pt) 1997-12-11 2007-09-07 Merial Sas Síndrome multi-sistémica do definhamento pós-desmame de porcos
JP2003111591A (ja) 2001-10-03 2003-04-15 Nippon Zeon Co Ltd 豚痘ウイルスのｄｎａ領域、及びそれを利用した組み換え豚痘ウイルス
CA2687146C (en) 2007-05-11 2015-07-21 Temasek Life Sciences Laboratory Limited Production of a homogeneous cell line highly permissive to porcine circovirus type 2 (pcv2) infection
CA2710247C (en) 2007-12-21 2014-02-18 Wyeth Llc Methods and compositions for immunizing pigs against porcine circovirus
KR20110128267A (ko) 2008-11-28 2011-11-29 세바 상뜨 아니말르 신규 돼지 시르코바이러스 2비 형 분리물 및 이의 용도
US20100150959A1 (en) 2008-12-15 2010-06-17 Vectogen Pty Ltd. PCV 2-Based Methods and Compositions for the Treatment of Pigs
EP2564869A1 (en) 2011-09-02 2013-03-06 Ceva Sante Animale Synthetic capsid proteins and uses thereof
EP2789346A1 (en) * 2013-04-11 2014-10-15 CEVA Santé Animale SA Fusion polypeptides and vaccines
PE20160673A1 (es) * 2013-08-22 2016-07-21 Univ Of Pittsburgh - Of The Commonwealth System Of Higher Education Terapias inmuno-oncoliticas
EP3034609A1 (en) * 2014-12-19 2016-06-22 Ceva Sante Animale Recombinant swinepox virus and vaccines

Also Published As

Publication number Publication date
RU2019100020A3 (pt) 2020-12-10
CA3027196A1 (en) 2017-12-14
WO2017212048A1 (en) 2017-12-14
PH12018502576A1 (en) 2019-10-28
RU2766008C2 (ru) 2022-02-07
US11020472B2 (en) 2021-06-01
CN109562157A (zh) 2019-04-02
RU2019100020A (ru) 2020-07-13
EP3254692A1 (en) 2017-12-13
US20190307876A1 (en) 2019-10-10
CN109562157B (zh) 2022-07-12
MX2018015341A (es) 2019-04-25

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]