CO2021014018A2 - Inmunoensayo de flujo lateral para medir el inhibidor de la esterasa c1 (inh c1) funcional en muestras de plasma - Google Patents

Inmunoensayo de flujo lateral para medir el inhibidor de la esterasa c1 (inh c1) funcional en muestras de plasma

Info

Publication number
CO2021014018A2
CO2021014018A2 CONC2021/0014018A CO2021014018A CO2021014018A2 CO 2021014018 A2 CO2021014018 A2 CO 2021014018A2 CO 2021014018 A CO2021014018 A CO 2021014018A CO 2021014018 A2 CO2021014018 A2 CO 2021014018A2
Authority
CO
Colombia
Prior art keywords
inh
zone
esterase inhibitor
lateral flow
plasma samples
Prior art date
Application number
CONC2021/0014018A
Other languages
English (en)
Inventor
Priya Sethu Chockalingam
Zhiwei Zhou
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of CO2021014018A2 publication Critical patent/CO2021014018A2/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Un dispositivo para detectar y/o cuantificar un inhibidor de la esterasa C1 funcional (INH C1f), el dispositivo comprende: (i) una almohadilla de conjugado que comprende una primera zona y una segunda zona, en la que un primer agente y un segundo agente están inmovilizados, respectivamente, y (ii) una membrana, que está en comunicación con la almohadilla de conjugado, en la que la membrana comprende una tercera zona, en la que un tercer agente está inmovilizado. La almohadilla de conjugado puede comprender además una cuarta zona para colocar una muestra biológica, que fluye a través del dispositivo en el orden de la primera zona, la segunda zona y la tercera zona.
CONC2021/0014018A 2019-04-12 2021-10-20 Inmunoensayo de flujo lateral para medir el inhibidor de la esterasa c1 (inh c1) funcional en muestras de plasma CO2021014018A2 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962833235P 2019-04-12 2019-04-12
US201962930615P 2019-11-05 2019-11-05
PCT/US2020/027406 WO2020210446A1 (en) 2019-04-12 2020-04-09 Lateral flow immunoassay for measuring functional c1-esterase inhibitor (c1-inh) in plasma samples

Publications (1)

Publication Number Publication Date
CO2021014018A2 true CO2021014018A2 (es) 2021-10-29

Family

ID=70476506

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2021/0014018A CO2021014018A2 (es) 2019-04-12 2021-10-20 Inmunoensayo de flujo lateral para medir el inhibidor de la esterasa c1 (inh c1) funcional en muestras de plasma

Country Status (12)

Country Link
EP (1) EP3953711A1 (es)
JP (1) JP7481361B2 (es)
KR (1) KR20210151180A (es)
CN (1) CN114341643A (es)
AU (1) AU2020271846A1 (es)
BR (1) BR112021020410A2 (es)
CA (1) CA3136694A1 (es)
CO (1) CO2021014018A2 (es)
IL (1) IL287208A (es)
MX (1) MX2021012444A (es)
TW (1) TW202104898A (es)
WO (1) WO2020210446A1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US4703017C1 (en) 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
US4881175A (en) 1986-09-02 1989-11-14 Genex Corporation Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4855240A (en) 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
GB9823397D0 (en) 1998-10-27 1998-12-23 Rsr Ltd Assays for thyroid autoantibodies
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
KR102658793B1 (ko) 2013-01-20 2024-04-19 다케다 파머수티컬 컴패니 리미티드 pKal 매개 장애의 평가, 검정 및 치료
CO2018007151A2 (es) 2015-12-11 2018-09-20 Dyax Corp Inhibidores de calicreína plasmática y usos de los mismos para tratar ataque de angioedema hereditario

Also Published As

Publication number Publication date
KR20210151180A (ko) 2021-12-13
JP2022526186A (ja) 2022-05-23
CA3136694A1 (en) 2020-10-15
JP7481361B2 (ja) 2024-05-10
TW202104898A (zh) 2021-02-01
EP3953711A1 (en) 2022-02-16
CN114341643A (zh) 2022-04-12
MX2021012444A (es) 2021-12-10
WO2020210446A1 (en) 2020-10-15
AU2020271846A1 (en) 2021-11-18
BR112021020410A2 (pt) 2021-12-07
IL287208A (en) 2021-12-01

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