CO2021004019A2 - Vacunas peptídicas - Google Patents

Vacunas peptídicas

Info

Publication number
CO2021004019A2
CO2021004019A2 CONC2021/0004019A CO2021004019A CO2021004019A2 CO 2021004019 A2 CO2021004019 A2 CO 2021004019A2 CO 2021004019 A CO2021004019 A CO 2021004019A CO 2021004019 A2 CO2021004019 A2 CO 2021004019A2
Authority
CO
Colombia
Prior art keywords
cancer
polypeptides
treatment
pharmaceutical compositions
peptides
Prior art date
Application number
CONC2021/0004019A
Other languages
English (en)
Inventor
Eszter Somogyi
Julianna Liszewicz
Levente Molnar
Eniko Toke
József Toth
Orsolya Lorincz
Zsolt Csiszovszk
Katalin Pantya
Mónika Megyesi
Original Assignee
Treos Bio Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1814367.7A external-priority patent/GB201814367D0/en
Priority claimed from GBGB1814366.9A external-priority patent/GB201814366D0/en
Priority claimed from GBGB1814364.4A external-priority patent/GB201814364D0/en
Priority claimed from GBGB1814365.1A external-priority patent/GB201814365D0/en
Application filed by Treos Bio Ltd filed Critical Treos Bio Ltd
Publication of CO2021004019A2 publication Critical patent/CO2021004019A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001148—Regulators of development
    • A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001166—Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001186—MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001189—PRAME
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/828—Stomach
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

La descripción se refiere a polipéptidos y composiciones farmacéuticas que comprenden polipéptidos que encuentran utilidad en la prevención o el tratamiento del cáncer, en particular cáncer gástrico, cáncer de pulmón, melanoma y cáncer de vejiga. La descripción también se refiere a métodos para inducir una respuesta de linfocitos T citotóxicos en un sujeto o tratar un cáncer administrando composiciones farmacéuticas que comprenden los péptidos, y a métodos de diagnóstico complementarios para identificar sujetos para el tratamiento. Los péptidos comprenden epítopos de linfocitos T que son inmunogénicos en un porcentaje alto de pacientes.
CONC2021/0004019A 2018-09-04 2021-03-30 Vacunas peptídicas CO2021004019A2 (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1814367.7A GB201814367D0 (en) 2018-09-04 2018-09-04 Peptide Vaccines
GBGB1814366.9A GB201814366D0 (en) 2018-09-04 2018-09-04 Peptide vaccines
GBGB1814364.4A GB201814364D0 (en) 2018-09-04 2018-09-04 Peptide vaccines
GBGB1814365.1A GB201814365D0 (en) 2018-09-04 2018-09-04 Peptide vaccines
PCT/EP2019/073476 WO2020048990A1 (en) 2018-09-04 2019-09-03 Peptide vaccines

Publications (1)

Publication Number Publication Date
CO2021004019A2 true CO2021004019A2 (es) 2021-07-19

Family

ID=67874441

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2021/0004019A CO2021004019A2 (es) 2018-09-04 2021-03-30 Vacunas peptídicas

Country Status (15)

Country Link
US (2) US11666644B2 (es)
EP (1) EP3846845A1 (es)
JP (1) JP2021536487A (es)
KR (1) KR20210086612A (es)
CN (1) CN113329761A (es)
AU (1) AU2019334437A1 (es)
BR (1) BR112021004071A2 (es)
CA (1) CA3110760A1 (es)
CL (1) CL2021000532A1 (es)
CO (1) CO2021004019A2 (es)
IL (1) IL281224A (es)
MA (1) MA53543A (es)
MX (1) MX2021002449A (es)
SG (1) SG11202101888YA (es)
WO (1) WO2020048990A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3054861A1 (en) 2017-03-03 2018-09-07 Treos Bio Zrt Peptide vaccines
CN113329761A (zh) 2018-09-04 2021-08-31 特雷斯生物有限公司 肽疫苗
AU2022270361A1 (en) 2021-05-05 2023-11-16 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame

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Also Published As

Publication number Publication date
BR112021004071A2 (pt) 2021-06-01
US11666644B2 (en) 2023-06-06
KR20210086612A (ko) 2021-07-08
CN113329761A (zh) 2021-08-31
WO2020048990A1 (en) 2020-03-12
JP2021536487A (ja) 2021-12-27
SG11202101888YA (en) 2021-03-30
AU2019334437A1 (en) 2021-03-18
IL281224A (en) 2021-04-29
MX2021002449A (es) 2021-08-05
US20230102031A1 (en) 2023-03-30
US20240000911A1 (en) 2024-01-04
EP3846845A1 (en) 2021-07-14
CA3110760A1 (en) 2020-03-12
MA53543A (fr) 2021-07-14
CL2021000532A1 (es) 2021-09-24

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