CO2017010191A2 - Éteres de celulosa esterificados solubles en agua que tienen grado bajo de neutralización - Google Patents
Éteres de celulosa esterificados solubles en agua que tienen grado bajo de neutralizaciónInfo
- Publication number
- CO2017010191A2 CO2017010191A2 CONC2017/0010191A CO2017010191A CO2017010191A2 CO 2017010191 A2 CO2017010191 A2 CO 2017010191A2 CO 2017010191 A CO2017010191 A CO 2017010191A CO 2017010191 A2 CO2017010191 A2 CO 2017010191A2
- Authority
- CO
- Colombia
- Prior art keywords
- esterified cellulose
- neutralization
- water
- low degree
- cellulose ethers
- Prior art date
Links
- 229920003086 cellulose ether Polymers 0.000 title abstract 3
- 238000006386 neutralization reaction Methods 0.000 title abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B13/00—Preparation of cellulose ether-esters
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/20—Post-etherification treatments of chemical or physical type, e.g. mixed etherification in two steps, including purification
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/32—Cellulose ether-esters
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
RESUMEN DE LA INVENCIÓN La presente invención se refiere a un éter de celulosa esterificado que comprende grupos acilo monovalentes alifáticos y grupos de la fórmula -C(O)-R-COOH, R siendo un grupo hidrocarburo divalente, tiene las siguientes propiedades: i) el grado de neutralización de los grupos -C(O)-R-COOH no es más de 0.4, ii) el grado total de la sustitución de éster es desde 0.10 hasta 0.70, y iii) el éter de celulosa esterificado tiene una solubilidad en agua de al menos 2.0 porciento en peso a 2 C.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562133514P | 2015-03-16 | 2015-03-16 | |
PCT/US2016/021330 WO2016148977A1 (en) | 2015-03-16 | 2016-03-08 | Water-soluble esterified cellulose ethers having a low degree of neutralization |
Publications (1)
Publication Number | Publication Date |
---|---|
CO2017010191A2 true CO2017010191A2 (es) | 2018-01-05 |
Family
ID=55590149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CONC2017/0010191A CO2017010191A2 (es) | 2015-03-16 | 2017-10-06 | Éteres de celulosa esterificados solubles en agua que tienen grado bajo de neutralización |
Country Status (9)
Country | Link |
---|---|
US (1) | US10214594B2 (es) |
EP (1) | EP3270971B1 (es) |
JP (1) | JP6356922B2 (es) |
KR (1) | KR20170128358A (es) |
CN (1) | CN107428847B (es) |
BR (1) | BR112017018260A2 (es) |
CO (1) | CO2017010191A2 (es) |
MX (1) | MX2017011095A (es) |
WO (1) | WO2016148977A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2017011128A (es) | 2015-03-16 | 2017-11-28 | Dow Global Technologies Llc | Eteres de celulosa esterificada de gelificacion. |
BR112017018232A2 (pt) | 2015-03-16 | 2018-04-17 | Dow Global Technologies Llc | éteres de celulose esterificados solúveis em água |
WO2017058973A1 (en) * | 2015-10-02 | 2017-04-06 | Dow Global Technologies Llc | Aqueous composition comprising dispersed esterified cellulose ether |
JP6546346B2 (ja) | 2015-12-08 | 2019-07-17 | ダウ グローバル テクノロジーズ エルエルシー | セルロースエーテル及び水溶性エステル化セルロースエーテルを含む組成物 |
WO2017146853A1 (en) | 2016-02-24 | 2017-08-31 | Dow Global Technologies Llc | Aqueous composition comprising water-soluble esterified cellulose ethers |
CN109312001B (zh) * | 2016-06-23 | 2020-03-03 | 陶氏环球技术有限责任公司 | 包含邻苯二甲酰基的酯化纤维素醚 |
EP3596131B1 (en) * | 2017-03-17 | 2021-05-05 | Nutrition & Biosciences USA 1, LLC | Process for recovering an esterified cellulose ether from a reaction product mixture |
US20200108130A1 (en) * | 2017-03-21 | 2020-04-09 | Synthetic Biologics, Inc. | Beta-lactamase formulations |
WO2019022822A1 (en) | 2017-07-26 | 2019-01-31 | Dow Global Technologies Llc | WATER-SOLUBLE POLYSACCHARIDES WITH IMPROVED PALABILITY |
WO2019022819A1 (en) | 2017-07-26 | 2019-01-31 | Dow Global Technologies Llc | PROCESS FOR PRODUCING HYDROGELS BASED ON LOW MOLECULAR WEIGHT HUMAN EMIER CELLULOSE ETHERS |
WO2019022818A1 (en) | 2017-07-26 | 2019-01-31 | Dow Global Technologies Llc | PROCESS FOR PRODUCING HYDROGELS BASED ON ESTERIFIED CELLULOSE ETHERS |
WO2019108264A1 (en) | 2017-11-29 | 2019-06-06 | Dow Global Technologies Llc | Hydrogels based on esterified cellulose ethers |
WO2020117736A1 (en) | 2018-12-04 | 2020-06-11 | DDP Specialty Electronic Materials US, Inc. | Hydroxypropyl methylcellulose acetate succinates of very high molecular weight |
WO2020131785A1 (en) | 2018-12-18 | 2020-06-25 | DDP Specialty Electronic Materials US, Inc. | A sustained release composition comprising a hydroxypropyl methylcellulose acetate succinate |
WO2020131801A1 (en) * | 2018-12-18 | 2020-06-25 | DDP Specialty Electronic Materials US, Inc. | A sustained release composition comprising a hydroxypropyl methylcellulose acetate succinate |
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US4226981A (en) | 1977-09-28 | 1980-10-07 | Shin-Etsu Chemical Co., Ltd. | Ether-ester derivatives of cellulose and their applications |
DE2917104A1 (de) | 1979-04-27 | 1980-11-06 | Hoechst Ag | Verfahren zur viskositaetserniedrigung von celluloseethern durch ozon und seine verwendung |
US4365060A (en) | 1979-04-28 | 1982-12-21 | Shin-Etsu Chemical Co. Ltd. | Enterosoluble capsules |
JPS572218A (en) * | 1980-06-05 | 1982-01-07 | Shionogi & Co Ltd | Capsule agent for rectal administration |
JPS5763301A (en) * | 1980-10-06 | 1982-04-16 | Shin Etsu Chem Co Ltd | Cellulose ether acidic succinoyl and acidic phthaloyl mixed ester |
JPS6225101A (ja) | 1985-07-24 | 1987-02-03 | Shin Etsu Chem Co Ltd | 低重合度セルロ−スエ−テルの製造方法 |
JPS6281402A (ja) | 1985-10-07 | 1987-04-14 | Shin Etsu Chem Co Ltd | セルロ−スエ−テル酸性ジカルボン酸エステルの製造方法 |
JP3149122B2 (ja) | 1994-11-07 | 2001-03-26 | 信越化学工業株式会社 | 固形腸溶製剤のコーティング用基剤 |
EP0872233A1 (en) | 1997-04-14 | 1998-10-21 | Janssen Pharmaceutica N.V. | Antiretroviral compositions with improved bioavailability |
US6261218B1 (en) | 1998-12-01 | 2001-07-17 | The Dow Chemical Company | Process and apparatus for making low molecular weight cellulose ethers |
DE10141680B4 (de) | 2001-08-25 | 2004-02-26 | Clariant Gmbh | Verfahren zur Herstellung niederviskoser Celluloseether durch sauer-oxidativen Abbau von gemahlenen und getrockneten Celluloseethern |
JP2008501009A (ja) | 2004-05-28 | 2008-01-17 | ファイザー・プロダクツ・インク | 性能を高めた医薬組成物 |
KR101705204B1 (ko) | 2009-09-11 | 2017-02-09 | 롯데정밀화학 주식회사 | 장용성 경질 캡슐용 수성 조성물, 장용성 경질 캡슐의 제조방법 및 장용성 경질 캡슐 |
MX2012014849A (es) | 2010-06-14 | 2013-05-01 | Dow Global Technologies Llc | Acetato succinato de hidroxipropil metil celulosa con substitucion de acetato de y succinato intensificada. |
EP2831121B1 (en) | 2012-03-27 | 2018-10-10 | Dow Global Technologies LLC | A process of preparing an ester of a cellulose ether |
KR20140146181A (ko) * | 2012-04-11 | 2014-12-24 | 다우 글로벌 테크놀로지스 엘엘씨 | 특정 치환체 분포를 갖는 에스테르화된 셀룰로즈 에테르 |
US10463625B2 (en) | 2012-05-02 | 2019-11-05 | Capsugel Belgium Nv | Bulk enteric capsule shells |
JP6254593B2 (ja) * | 2012-08-24 | 2017-12-27 | ダウ グローバル テクノロジーズ エルエルシー | カルボン酸アルカリ金属塩の存在下でセルロースエーテルのエステルを調製する方法 |
WO2014031446A1 (en) * | 2012-08-24 | 2014-02-27 | Dow Global Technologies Llc | Process of preparing an esterified cellulose ether in the presence of an alkali metal carboxylate and an aliphatic carboxylic acid |
CN107602710A (zh) | 2012-08-24 | 2018-01-19 | 陶氏环球技术有限责任公司 | 新的具有高分子量和均匀性的酯化纤维素醚 |
EP2888293B1 (en) * | 2012-08-24 | 2019-05-08 | Dow Global Technologies LLC | Novel hydroxyalkyl methyl cellulose acetate succinates |
EP2888291A1 (en) * | 2012-08-24 | 2015-07-01 | Dow Global Technologies LLC | Process for preparing an ester of a cellulose ether in the presence of an aliphatic carboxylic acid |
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EP3021871A1 (en) | 2013-07-17 | 2016-05-25 | Dow Global Technologies LLC | Composition for application to a mucosa comprising a methylcellulose |
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MX2017011128A (es) * | 2015-03-16 | 2017-11-28 | Dow Global Technologies Llc | Eteres de celulosa esterificada de gelificacion. |
WO2016148970A1 (en) * | 2015-03-16 | 2016-09-22 | Dow Global Technologies Llc | Aqueous solution of an esterified cellulose ether |
-
2016
- 2016-03-08 EP EP16711737.3A patent/EP3270971B1/en not_active Not-in-force
- 2016-03-08 BR BR112017018260A patent/BR112017018260A2/pt not_active IP Right Cessation
- 2016-03-08 KR KR1020177026780A patent/KR20170128358A/ko not_active Application Discontinuation
- 2016-03-08 JP JP2017545912A patent/JP6356922B2/ja not_active Expired - Fee Related
- 2016-03-08 US US15/550,097 patent/US10214594B2/en not_active Expired - Fee Related
- 2016-03-08 CN CN201680013459.2A patent/CN107428847B/zh not_active Expired - Fee Related
- 2016-03-08 WO PCT/US2016/021330 patent/WO2016148977A1/en active Application Filing
- 2016-03-08 MX MX2017011095A patent/MX2017011095A/es unknown
-
2017
- 2017-10-06 CO CONC2017/0010191A patent/CO2017010191A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
US10214594B2 (en) | 2019-02-26 |
CN107428847A (zh) | 2017-12-01 |
BR112017018260A2 (pt) | 2018-04-10 |
EP3270971B1 (en) | 2019-01-09 |
US20180072819A1 (en) | 2018-03-15 |
EP3270971A1 (en) | 2018-01-24 |
MX2017011095A (es) | 2017-11-10 |
JP6356922B2 (ja) | 2018-07-11 |
KR20170128358A (ko) | 2017-11-22 |
WO2016148977A1 (en) | 2016-09-22 |
JP2018507306A (ja) | 2018-03-15 |
CN107428847B (zh) | 2018-11-16 |
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