EA201791151A1 - Новая кристаллическая форма производного бензимидазола и способ ее получения - Google Patents

Новая кристаллическая форма производного бензимидазола и способ ее получения

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Publication number
EA201791151A1
EA201791151A1 EA201791151A EA201791151A EA201791151A1 EA 201791151 A1 EA201791151 A1 EA 201791151A1 EA 201791151 A EA201791151 A EA 201791151A EA 201791151 A EA201791151 A EA 201791151A EA 201791151 A1 EA201791151 A1 EA 201791151A1
Authority
EA
Eurasian Patent Office
Prior art keywords
crystalline form
preparation
benzimidazole
derivative
crystal form
Prior art date
Application number
EA201791151A
Other languages
English (en)
Other versions
EA030919B1 (ru
Inventor
Ён Джу Ким
Ын Сон Ким
Джи Юн Ли
Хёк У Ли
Дже Хон Квон
Сон А Ли
Кван До Чой
Дон Хён Ко
Сын Пён Хо
Original Assignee
СиДжей ХЕЛТКЕР КОРПОРЕЙШН
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56417901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201791151(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by СиДжей ХЕЛТКЕР КОРПОРЕЙШН filed Critical СиДжей ХЕЛТКЕР КОРПОРЕЙШН
Publication of EA201791151A1 publication Critical patent/EA201791151A1/ru
Publication of EA030919B1 publication Critical patent/EA030919B1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Настоящее изобретение относится к новой кристаллической форме производного бензимидазола и способу ее получения. Новая кристаллическая форма по настоящему изобретению не меняет свои свойства в условиях сильной освещенности в течение длительного времени, имеет низкое влагопоглощение и обладает чрезвычайно низкой способностью индуцировать статическое электричество, что позволяет легко приготавливать композиции из данной кристаллической формы. Кроме того, данная кристаллическая форма обладает превосходной стабильностью и пригодна для длительного хранения.
EA201791151A 2015-01-20 2015-11-18 Новая кристаллическая форма производного бензимидазола и способ ее получения EA030919B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020150009326A KR101684053B1 (ko) 2015-01-20 2015-01-20 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법
PCT/KR2015/012385 WO2016117814A2 (ko) 2015-01-20 2015-11-18 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법

Publications (2)

Publication Number Publication Date
EA201791151A1 true EA201791151A1 (ru) 2017-12-29
EA030919B1 EA030919B1 (ru) 2018-10-31

Family

ID=56417901

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201791151A EA030919B1 (ru) 2015-01-20 2015-11-18 Новая кристаллическая форма производного бензимидазола и способ ее получения

Country Status (32)

Country Link
US (1) US9908870B2 (ru)
EP (1) EP3248967B1 (ru)
JP (2) JP6535748B2 (ru)
KR (1) KR101684053B1 (ru)
CN (2) CN111187259B (ru)
AR (1) AR103444A1 (ru)
BR (1) BR102016001167B1 (ru)
CL (1) CL2017001377A1 (ru)
CO (1) CO2017005396A2 (ru)
CY (1) CY1123423T1 (ru)
DK (1) DK3248967T3 (ru)
EA (1) EA030919B1 (ru)
EC (1) ECSP17035416A (ru)
ES (1) ES2816646T3 (ru)
GE (1) GEP20196974B (ru)
HR (1) HRP20201275T1 (ru)
HU (1) HUE050979T2 (ru)
IL (1) IL253186B (ru)
JO (1) JO3592B1 (ru)
LT (1) LT3248967T (ru)
MX (1) MX359916B (ru)
MY (1) MY186830A (ru)
PH (2) PH12016000029A1 (ru)
PL (1) PL3248967T3 (ru)
PT (1) PT3248967T (ru)
RS (1) RS60758B1 (ru)
SA (1) SA517381904B1 (ru)
SG (1) SG10201509488YA (ru)
SI (1) SI3248967T1 (ru)
TW (1) TWI589575B (ru)
UY (1) UY36521A (ru)
WO (1) WO2016117814A2 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101829706B1 (ko) 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 산부가염
KR20230114163A (ko) 2022-01-24 2023-08-01 엠에프씨 주식회사 칼륨 경쟁적 위산분비억제제 계열 약물의 신규한 무정형 고체분산체 및 그의 제조방법
KR20230114164A (ko) 2022-01-24 2023-08-01 엠에프씨 주식회사 벤즈이미다졸 유도체의 공동 무정형 고형체, 이의 제조방법 및 이를 포함하는 약제학적 조성물
KR20240028127A (ko) 2022-08-24 2024-03-05 위더스제약주식회사 테고프라잔 고체분산체 조성물
WO2024045255A1 (zh) * 2022-08-30 2024-03-07 上海皓元医药股份有限公司 一种特戈拉赞晶型b及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043063A1 (es) * 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
ES2332534T3 (es) 2005-06-14 2010-02-08 Raqualia Pharma Inc Derivados de bencimidazol sustituidos con cromano como antagonistas de la bomba de acidos.
JP4481344B2 (ja) * 2005-12-19 2010-06-16 ラクオリア創薬株式会社 クロマン置換ベンゾイミダゾール誘導体及び酸ポンプ阻害剤としてのそれらの使用
EP2650297A1 (en) * 2008-07-03 2013-10-16 Ratiopharm GmbH Crystalline salts of sitagliptin
BRPI1013288A2 (pt) * 2009-07-09 2016-03-29 Raqualia Pharma Inc uso de um composto, método de composição farmacêutica para o tratamento de doenças em que a motilidade gastrointestinal anormal está envolvida, kit e embalagem comercial que compreende uma composição farmacêutica contendo o composto
JP2014047304A (ja) * 2012-08-31 2014-03-17 Sanyo Chem Ind Ltd 樹脂粒子の製造方法
GB2508352B (en) * 2012-11-28 2017-08-16 Douwe Egberts Bv Treating soluble coffee
WO2014110344A1 (en) * 2013-01-11 2014-07-17 Novartis Ag Meglumine salt forms of 2-((1 r,4r)-4-(4-(5-(benzoxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl) acetic acid and their use as dgat1 inhibitors
PE20171259A1 (es) * 2014-12-19 2017-08-28 Glaxosmithkline Ip Dev Ltd Compuestos

Also Published As

Publication number Publication date
PL3248967T3 (pl) 2020-12-28
IL253186A (en) 2018-04-30
US20180009791A1 (en) 2018-01-11
MX359916B (es) 2018-10-15
KR20160089928A (ko) 2016-07-29
MY186830A (en) 2021-08-24
CN111187259A (zh) 2020-05-22
SG10201509488YA (en) 2016-08-30
TWI589575B (zh) 2017-07-01
JO3592B1 (ar) 2020-07-05
AR103444A1 (es) 2017-05-10
HRP20201275T1 (hr) 2020-11-13
WO2016117814A3 (ko) 2016-10-06
UY36521A (es) 2016-08-31
CY1123423T1 (el) 2021-12-31
CL2017001377A1 (es) 2017-12-15
JP2018502140A (ja) 2018-01-25
CN107207478A (zh) 2017-09-26
EP3248967B1 (en) 2020-06-24
ECSP17035416A (es) 2017-11-30
CN111187259B (zh) 2023-10-13
HUE050979T2 (hu) 2021-01-28
EP3248967A4 (en) 2018-10-03
EA030919B1 (ru) 2018-10-31
EP3248967A2 (en) 2017-11-29
DK3248967T3 (da) 2020-09-07
RS60758B1 (sr) 2020-10-30
TW201627305A (zh) 2016-08-01
SA517381904B1 (ar) 2020-12-07
KR101684053B1 (ko) 2016-12-08
PH12016000029B1 (en) 2017-07-24
PH12016000029A1 (en) 2017-07-24
SI3248967T1 (sl) 2020-11-30
CN107207478B (zh) 2020-09-01
US9908870B2 (en) 2018-03-06
GEP20196974B (en) 2019-06-10
WO2016117814A2 (ko) 2016-07-28
ES2816646T3 (es) 2021-04-05
BR102016001167B1 (pt) 2023-03-07
JP2019104760A (ja) 2019-06-27
JP6535748B2 (ja) 2019-06-26
PT3248967T (pt) 2020-09-11
LT3248967T (lt) 2020-10-12
CO2017005396A2 (es) 2017-07-11
BR102016001167A2 (pt) 2018-03-20
MX2016000751A (es) 2016-08-11
PH12019000462A1 (en) 2020-10-12
IL253186B (en) 2020-11-30

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