MX359916B - Una nueva forma cristalina de un derivado de bencimidazol y un método de preparación de los mismos. - Google Patents

Una nueva forma cristalina de un derivado de bencimidazol y un método de preparación de los mismos.

Info

Publication number
MX359916B
MX359916B MX2016000751A MX2016000751A MX359916B MX 359916 B MX359916 B MX 359916B MX 2016000751 A MX2016000751 A MX 2016000751A MX 2016000751 A MX2016000751 A MX 2016000751A MX 359916 B MX359916 B MX 359916B
Authority
MX
Mexico
Prior art keywords
crystal form
preparation
novel crystal
benzimidazole derivative
present
Prior art date
Application number
MX2016000751A
Other languages
English (en)
Other versions
MX2016000751A (es
Inventor
Eun Sun Kim
Ju Kim Young
Yun LEE Ji
Woo LEE Hyuk
Hong Kweon Jae
Ah LEE Sung
Do Choi Kwang
Hyun Ko Dong
Pyeong HEO Seung
Original Assignee
Cj Healthcare Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56417901&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX359916(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cj Healthcare Corp filed Critical Cj Healthcare Corp
Publication of MX2016000751A publication Critical patent/MX2016000751A/es
Publication of MX359916B publication Critical patent/MX359916B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a una nueva forma cristalina de un derivado de bencimidazol y un procedimiento de preparación de estos. La nueva forma cristalina de acuerdo con la presente invención apenas cambia de forma química y/o física en un estado de foto-estrés de largo plazo, tiene higroscopicidad baja y tiene una capacidad inductora de electricidad estática extremadamente baja, de este modo es ventajosa para la formulación, y debido a la excelente estabilidad de la forma de cristal misma, es muy útil para el almacenamiento a largo plazo del compuesto.
MX2016000751A 2015-01-20 2016-01-19 Una nueva forma cristalina de un derivado de bencimidazol y un método de preparación de los mismos. MX359916B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020150009326A KR101684053B1 (ko) 2015-01-20 2015-01-20 벤즈이미다졸 유도체의 신규 결정형 및 이의 제조방법

Publications (2)

Publication Number Publication Date
MX2016000751A MX2016000751A (es) 2016-08-11
MX359916B true MX359916B (es) 2018-10-15

Family

ID=56417901

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016000751A MX359916B (es) 2015-01-20 2016-01-19 Una nueva forma cristalina de un derivado de bencimidazol y un método de preparación de los mismos.

Country Status (32)

Country Link
US (1) US9908870B2 (es)
EP (1) EP3248967B1 (es)
JP (2) JP6535748B2 (es)
KR (1) KR101684053B1 (es)
CN (2) CN111187259B (es)
AR (1) AR103444A1 (es)
BR (1) BR102016001167B1 (es)
CL (1) CL2017001377A1 (es)
CO (1) CO2017005396A2 (es)
CY (1) CY1123423T1 (es)
DK (1) DK3248967T3 (es)
EA (1) EA030919B1 (es)
EC (1) ECSP17035416A (es)
ES (1) ES2816646T3 (es)
GE (1) GEP20196974B (es)
HR (1) HRP20201275T1 (es)
HU (1) HUE050979T2 (es)
IL (1) IL253186B (es)
JO (1) JO3592B1 (es)
LT (1) LT3248967T (es)
MX (1) MX359916B (es)
MY (1) MY186830A (es)
PH (2) PH12016000029B1 (es)
PL (1) PL3248967T3 (es)
PT (1) PT3248967T (es)
RS (1) RS60758B1 (es)
SA (1) SA517381904B1 (es)
SG (1) SG10201509488YA (es)
SI (1) SI3248967T1 (es)
TW (1) TWI589575B (es)
UY (1) UY36521A (es)
WO (1) WO2016117814A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101829706B1 (ko) * 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 산부가염
KR20230114164A (ko) 2022-01-24 2023-08-01 엠에프씨 주식회사 벤즈이미다졸 유도체의 공동 무정형 고형체, 이의 제조방법 및 이를 포함하는 약제학적 조성물
KR20230114163A (ko) 2022-01-24 2023-08-01 엠에프씨 주식회사 칼륨 경쟁적 위산분비억제제 계열 약물의 신규한 무정형 고체분산체 및 그의 제조방법
KR20240028127A (ko) 2022-08-24 2024-03-05 위더스제약주식회사 테고프라잔 고체분산체 조성물
WO2024045255A1 (zh) * 2022-08-30 2024-03-07 上海皓元医药股份有限公司 一种特戈拉赞晶型b及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043063A1 (es) 2002-12-13 2005-07-13 Altana Pharma Ag Bencimidazoles 6-sustituidos y su uso como inhibidores de secreciones gastricas
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
JP2008543824A (ja) 2005-06-14 2008-12-04 ファイザー株式会社 アシッドポンプアンタゴニストとしてのクロマン置換ベンゾイミダゾール誘導体
CN101341149B (zh) * 2005-12-19 2011-06-08 拉夸里亚创药株式会社 经色原烷取代的苯并咪唑类和它们作为酸泵抑制剂的用途
EP2650298A1 (en) * 2008-07-03 2013-10-16 Ratiopharm GmbH Crystalline salts of sitagliptin
JP5802898B2 (ja) * 2009-07-09 2015-11-04 ラクオリア創薬株式会社 消化管運動異常が関与する疾患を治療するためのアシッドポンプ拮抗剤
JP2014047304A (ja) * 2012-08-31 2014-03-17 Sanyo Chem Ind Ltd 樹脂粒子の製造方法
GB2508352B (en) * 2012-11-28 2017-08-16 Douwe Egberts Bv Treating soluble coffee
WO2014110344A1 (en) * 2013-01-11 2014-07-17 Novartis Ag Meglumine salt forms of 2-((1 r,4r)-4-(4-(5-(benzoxazol-2-ylamino)pyridin-2-yl)phenyl)cyclohexyl) acetic acid and their use as dgat1 inhibitors
JP6644790B2 (ja) * 2014-12-19 2020-02-12 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ キヌレニンモノオキシゲナーゼ阻害剤として有用な３−（６−アルコキシ−５−クロロベンゾ［ｄ］イソキサゾール−３−イル）プロパン酸

Also Published As

Publication number Publication date
CN107207478A (zh) 2017-09-26
EP3248967A4 (en) 2018-10-03
US20180009791A1 (en) 2018-01-11
IL253186B (en) 2020-11-30
PH12016000029A1 (en) 2017-07-24
EP3248967A2 (en) 2017-11-29
ECSP17035416A (es) 2017-11-30
PL3248967T3 (pl) 2020-12-28
SA517381904B1 (ar) 2020-12-07
ES2816646T3 (es) 2021-04-05
LT3248967T (lt) 2020-10-12
JP2018502140A (ja) 2018-01-25
EP3248967B1 (en) 2020-06-24
CN111187259A (zh) 2020-05-22
MX2016000751A (es) 2016-08-11
PH12016000029B1 (en) 2017-07-24
DK3248967T3 (da) 2020-09-07
WO2016117814A2 (ko) 2016-07-28
CN111187259B (zh) 2023-10-13
UY36521A (es) 2016-08-31
CN107207478B (zh) 2020-09-01
PT3248967T (pt) 2020-09-11
KR101684053B1 (ko) 2016-12-08
WO2016117814A3 (ko) 2016-10-06
BR102016001167A2 (pt) 2018-03-20
CL2017001377A1 (es) 2017-12-15
SG10201509488YA (en) 2016-08-30
HUE050979T2 (hu) 2021-01-28
EA030919B1 (ru) 2018-10-31
TWI589575B (zh) 2017-07-01
PH12019000462A1 (en) 2020-10-12
CO2017005396A2 (es) 2017-07-11
MY186830A (en) 2021-08-24
US9908870B2 (en) 2018-03-06
JP6535748B2 (ja) 2019-06-26
RS60758B1 (sr) 2020-10-30
BR102016001167B1 (pt) 2023-03-07
JP2019104760A (ja) 2019-06-27
SI3248967T1 (sl) 2020-11-30
HRP20201275T1 (hr) 2020-11-13
EA201791151A1 (ru) 2017-12-29
CY1123423T1 (el) 2021-12-31
AR103444A1 (es) 2017-05-10
JO3592B1 (ar) 2020-07-05
KR20160089928A (ko) 2016-07-29
GEP20196974B (en) 2019-06-10
IL253186A (en) 2018-04-30
TW201627305A (zh) 2016-08-01

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