CN219991584U - Stem cell collection and extraction equipment - Google Patents
Stem cell collection and extraction equipment Download PDFInfo
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- CN219991584U CN219991584U CN202321063887.XU CN202321063887U CN219991584U CN 219991584 U CN219991584 U CN 219991584U CN 202321063887 U CN202321063887 U CN 202321063887U CN 219991584 U CN219991584 U CN 219991584U
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- stem cell
- extraction
- extracting
- sample container
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- 210000000130 stem cell Anatomy 0.000 title claims abstract description 191
- 238000000605 extraction Methods 0.000 title claims abstract description 161
- 239000000523 sample Substances 0.000 claims abstract description 121
- 210000000078 claw Anatomy 0.000 claims abstract description 38
- 238000004113 cell culture Methods 0.000 claims abstract description 23
- 238000003306 harvesting Methods 0.000 claims 1
- 238000012258 culturing Methods 0.000 abstract description 8
- 238000000034 method Methods 0.000 abstract description 5
- 238000012546 transfer Methods 0.000 description 16
- 239000000203 mixture Substances 0.000 description 4
- 238000013459 approach Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000000926 separation method Methods 0.000 description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 210000001778 pluripotent stem cell Anatomy 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000003014 totipotent stem cell Anatomy 0.000 description 1
Landscapes
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to the technical field of biological extraction, in particular to stem cell collecting and extracting equipment, which comprises an extracting bin, an extracting cover plate, an extracting claw, an extracting probe, a stem cell sample container and a stem cell conveying pipeline. According to the utility model, the stem cell conveying pipeline is arranged on the conventional stem cell sample container, and the stem cell culturing bin is connected to the stem cell conveying pipeline, so that the stem cells in the stem cell culturing bin enter the stem cell sample container through the stem cell conveying pipeline by using the power system. The whole process keeps the extraction cover plate closed and arranged on the extraction bin, so that the environment inside the extraction bin is compounded with the culture environment of stem cells, and the influence on the stability of the stem cell culture environment in the extraction process is avoided. The stem cells are extracted by the extraction probes by using the extraction dry mix which is arranged on the extraction claw to drive the extraction probes to be close to the stem cell sample container. And returning the residual stem cell sample to the stem cell culture bin after the extraction is finished.
Description
Technical Field
The utility model relates to the technical field of biological extraction, in particular to stem cell collecting and extracting equipment.
Background
Stem cells generally refer to cells capable of infinitely self-renewing, and are commonly totipotent stem cells, pluripotent stem cells and monopotent stem cells, and because stem cells can infinitely self-renew, the stem cells have extremely broad application prospects in the field of medical health. In the stem cell culture process, a small amount of samples are required to be collected and extracted, so that the culture progress is measured.
The utility model with the publication number of CN218620789U discloses a stem cell collecting and extracting device, which strengthens the mixing effect by arranging a centrifugal machine, is convenient for fully mixing heparin and blood, avoids influencing the using effect of the heparin, and simultaneously is convenient for disassembly and cleaning and avoids influencing the reuse of a device.
However, the above technical solution has the following drawbacks: the device is mainly used for collecting and extracting stem cells in the stem cell separation process, the collecting and extracting amount in the stem cell separation process is large, and after the stem cells are completely collected after separation, a small amount of extraction is required to be carried out for testing so as to meet the requirements of staff on culture determination and stem cell research. The existing stem cell extraction equipment cannot meet the requirement of low-dose stem cell extraction, and the index of the culture environment is easily influenced in the extraction process.
Disclosure of Invention
Aiming at the technical problems in the background technology, the utility model provides a stem cell collecting and extracting device.
The technical scheme of the utility model is as follows: a stem cell collecting and extracting device comprises an extracting bin, an extracting cover plate, extracting claws, an extracting probe, a stem cell sample container and a stem cell conveying pipeline.
The extraction cover plate is rotatably arranged on the extraction bin; the stem cell sample container is arranged in the extraction bin; the extraction claw is arranged on the extraction cover plate; the extraction probe is arranged at one end of the extraction claw, which is close to the stem cell sample container; one end of the stem cell conveying pipeline is arranged on the stem cell culture bin, and the other end of the stem cell conveying pipeline is arranged on the stem cell sample container;
in the closed state of the extraction cover plate, the extraction probe is positioned above the stem cell sample container.
Preferably, the stem cell delivery driving member is further included; the stem cell conveying driving piece is arranged on the stem cell culture bin; the stem cell sample driven by the stem cell transfer driver passes from the stem cell culture bin through the stem cell transfer tubing into the stem cell sample container.
Preferably, the extraction probe is detachably provided on the extraction claw.
Preferably, the extraction claw comprises an extraction claw mounting seat, a sliding seat and an extraction probe mounting rod; the extraction claw mounting seat is arranged on the extraction cover plate; the sliding seat is arranged on the extracting claw mounting seat; the extraction probe mounting rod is arranged on the sliding seat in a sliding way; the extraction probe is arranged at one end of the extraction probe mounting rod, which is close to the stem cell sample container.
Preferably, the extraction probe mounting bar is provided as a threaded bar; the threaded rod is in threaded connection with the sliding seat; the extraction probe is disposed at one end of the threaded rod adjacent to the stem cell sample container.
Preferably, the extraction probe mounting rod is provided with a driving member; the extraction probe mounting rod driven by the driving piece is rotatably arranged relative to the sliding seat.
Preferably, the device further comprises an extraction grip and a connecting rod; the extraction gripper is rotatably arranged on the extraction gripper mounting seat; one end of the connecting rod is rotatably arranged on the extraction handle, and the other end of the connecting rod is rotatably arranged on the sliding seat.
Compared with the prior art, the technical scheme provided by the utility model has the following beneficial technical effects: the stem cells in the stem cell culture bin are led into the stem cell sample container through the stem cell conveying pipeline by using the power system through arranging the stem cell conveying pipeline on the conventional stem cell sample container and connecting the stem cell culture bin on the stem cell conveying pipeline. The whole process keeps the extraction cover plate closed and arranged on the extraction bin, so that the environment inside the extraction bin is compounded with the culture environment of stem cells, and the influence on the stability of the stem cell culture environment in the extraction process is avoided. The stem cells are extracted by the extraction probes by using the extraction dry mix which is arranged on the extraction claw to drive the extraction probes to be close to the stem cell sample container. And after the extraction is finished, returning the residual stem cell sample into the stem cell culture bin, and closing a valve of the stem cell conveying pipeline. And then opening the extraction cover plate to obtain a stem cell sample on the extraction probe. The utility model solves the technical problems that the stem cell extraction device in the prior art cannot extract a small amount of stem cell samples and the stem cell culture environment is possibly influenced in the extraction process.
Drawings
Fig. 1 is a schematic structural diagram of an embodiment of the present utility model.
Fig. 2 is a schematic diagram of a second embodiment of the present utility model.
Fig. 3 is a perspective view of an embodiment of the present utility model.
Reference numerals: 1. an extraction bin; 2. extracting a cover plate; 3. an extraction claw; 4. extracting the probe; 5. a stem cell sample container; 6. a stem cell delivery conduit; 7. a stem cell culture bin; 8. a stem cell delivery driver; 9. an extraction claw mounting seat; 10. extracting a gripper; 11. a sliding seat; 12. extracting a probe mounting rod; 13. a driving member; 14. and (5) connecting a rod.
Detailed Description
Example 1
The stem cell collecting and extracting device provided by the embodiment comprises an extracting bin 1, an extracting cover plate 2, extracting claws 3, an extracting probe 4, a stem cell sample container 5 and a stem cell conveying pipeline 6.
As shown in fig. 1-2, the extraction cover plate 2 is rotatably arranged on the extraction bin 1; the stem cell sample container 5 is arranged in the extraction bin 1; the extraction claw 3 is arranged on the extraction cover plate 2; the extraction probe 4 is arranged at one end of the extraction claw 3 close to the stem cell sample container 5; one end of the stem cell conveying pipeline 6 is arranged on the stem cell culture bin 7, and the other end of the stem cell conveying pipeline 6 is arranged on the stem cell sample container 5.
In the closed state of the extraction cover plate 2, the extraction probe 4 is located above the stem cell sample container 5.
In the present embodiment, by providing the stem cell transfer duct 6 on the conventional stem cell sample container 5 and connecting the stem cell culturing chamber 7 to the stem cell transfer duct 6, stem cells inside the stem cell culturing chamber 7 are introduced into the stem cell sample container 5 through the stem cell transfer duct 67 by using a power system. The whole process keeps the extraction cover plate 2 closed and arranged on the extraction bin 1, so that the environment inside the extraction bin 1 is compounded with the culture environment of stem cells, and the influence on the stability of the culture environment of stem cells in the extraction process is avoided. The extraction stem cells are extracted by the extraction probes 4 by driving the extraction probes 4 to approach the stem cell sample container 5 by the extraction stem mix 2 arranged on the extraction claw 3. After the extraction, the remaining stem cell sample is returned to the stem cell culture chamber 7, and the valve of the stem cell transfer pipe 6 is closed. The extraction cover 2 is then opened to obtain a stem cell sample on the extraction probe 4.
Example two
The stem cell collecting and extracting device provided by the embodiment comprises an extracting bin 1, an extracting cover plate 2, extracting claws 3, an extracting probe 4, a stem cell sample container 5 and a stem cell conveying pipeline 6.
As shown in fig. 1-2, the extraction cover plate 2 is rotatably arranged on the extraction bin 1; the stem cell sample container 5 is arranged in the extraction bin 1; the extraction claw 3 is arranged on the extraction cover plate 2; the extraction probe 4 is arranged at one end of the extraction claw 3 close to the stem cell sample container 5; one end of the stem cell conveying pipeline 6 is arranged on the stem cell culture bin 7, and the other end of the stem cell conveying pipeline 6 is arranged on the stem cell sample container 5.
In the closed state of the extraction cover plate 2, the extraction probe 4 is located above the stem cell sample container 5.
Further, the stem cell conveying driving part 8 is also included; the stem cell conveying driving piece 8 is arranged on the stem cell culture bin 7; the stem cell sample driven by the stem cell transfer driver 8 passes from the stem cell culture chamber 7 through the stem cell transfer tube 6 into the stem cell sample container 5.
In the present embodiment, by providing the stem cell transfer duct 6 on the conventional stem cell sample container 5 and connecting the stem cell culturing chamber 7 to the stem cell transfer duct 6, stem cells inside the stem cell culturing chamber 7 are introduced into the stem cell sample container 5 through the stem cell transfer duct 67 by using a power system. The whole process keeps the extraction cover plate 2 closed and arranged on the extraction bin 1, so that the environment inside the extraction bin 1 is compounded with the culture environment of stem cells, and the influence on the stability of the culture environment of stem cells in the extraction process is avoided. The extraction stem cells are extracted by the extraction probes 4 by driving the extraction probes 4 to approach the stem cell sample container 5 by the extraction stem mix 2 arranged on the extraction claw 3. After the extraction, the remaining stem cell sample is returned to the stem cell culture chamber 7, and the valve of the stem cell transfer pipe 6 is closed. The extraction cover 2 is then opened to obtain a stem cell sample on the extraction probe 4.
Example III
The stem cell collecting and extracting device provided by the embodiment comprises an extracting bin 1, an extracting cover plate 2, extracting claws 3, an extracting probe 4, a stem cell sample container 5 and a stem cell conveying pipeline 6.
As shown in fig. 1-2, the extraction cover plate 2 is rotatably arranged on the extraction bin 1; the stem cell sample container 5 is arranged in the extraction bin 1; the extraction claw 3 is arranged on the extraction cover plate 2; the extraction probe 4 is arranged at one end of the extraction claw 3 close to the stem cell sample container 5; one end of the stem cell conveying pipeline 6 is arranged on the stem cell culture bin 7, and the other end of the stem cell conveying pipeline 6 is arranged on the stem cell sample container 5.
In the closed state of the extraction cover plate 2, the extraction probe 4 is located above the stem cell sample container 5.
Further, the extraction probe 4 is detachably provided on the extraction claw 3.
Further, the extraction claw 3 includes an extraction claw mount 9, a slide mount 11, and an extraction probe mount lever 12; the extraction claw mounting seat 9 is arranged on the extraction cover plate 2; the sliding seat 11 is arranged on the extracting claw mounting seat 9; the extraction probe mounting rod 12 is slidably arranged on the sliding seat 11; the extraction probe 4 is disposed at one end of the extraction probe mounting stem 12 adjacent the stem cell sample container 5.
Further, the extraction probe mounting bar 12 is provided as a threaded bar; the threaded rod is in threaded connection with the sliding seat 11; the extraction probe 4 is disposed at one end of the threaded rod adjacent to the stem cell sample container 5.
Further, a driving member 13 is provided on the extraction probe mounting lever 12; the extraction probe mounting lever 12 driven by the driving member 13 is rotatably provided with respect to the slide mount 11. The driving member 13 may be configured as a meshing gear and a driving motor, a driving portion of the meshing gear is rotatably disposed on the sliding seat 11, and a meshing rotating portion of the meshing gear is disposed on the threaded rod, so that the threaded rod can be automatically lifted and lowered relative to the sliding seat 11.
Further, the device also comprises an extraction gripper 10 and a connecting rod 14; the extraction gripper 10 is rotatably arranged on the extraction gripper mounting seat 9; one end of the connecting rod 14 is rotatably provided on the extraction hand grip 10, and the other end of the connecting rod 14 is rotatably provided on the slide seat 11.
In the present embodiment, by providing the stem cell transfer duct 6 on the conventional stem cell sample container 5 and connecting the stem cell culturing chamber 7 to the stem cell transfer duct 6, stem cells inside the stem cell culturing chamber 7 are introduced into the stem cell sample container 5 through the stem cell transfer duct 67 by using a power system. The whole process keeps the extraction cover plate 2 closed and arranged on the extraction bin 1, so that the environment inside the extraction bin 1 is compounded with the culture environment of stem cells, and the influence on the stability of the culture environment of stem cells in the extraction process is avoided. The extraction stem cells are extracted by the extraction probes 4 by driving the extraction probes 4 to approach the stem cell sample container 5 by the extraction stem mix 2 arranged on the extraction claw 3. After the extraction, the remaining stem cell sample is returned to the stem cell culture chamber 7, and the valve of the stem cell transfer pipe 6 is closed. The extraction cover 2 is then opened to obtain a stem cell sample on the extraction probe 4.
It is to be understood that the above-described embodiments of the present utility model are merely illustrative of or explanation of the principles of the present utility model and are in no way limiting of the utility model. Accordingly, any modification, equivalent replacement, improvement, etc. made without departing from the spirit and scope of the present utility model should be included in the scope of the present utility model. Furthermore, the appended claims are intended to cover all such changes and modifications that fall within the scope and boundary of the appended claims, or equivalents of such scope and boundary.
Claims (7)
1. The stem cell collecting and extracting device comprises a stem cell sample container (5) and is characterized by comprising an extracting bin (1), an extracting cover plate (2), extracting claws (3), an extracting probe (4) and a stem cell conveying pipeline (6);
the extraction cover plate (2) is rotatably arranged on the extraction bin (1); the stem cell sample container (5) is arranged in the extraction bin (1); the extraction claw (3) is arranged on the extraction cover plate (2); the extraction probe (4) is arranged at one end of the extraction claw (3) close to the stem cell sample container (5); one end of a stem cell conveying pipeline (6) is arranged on the stem cell culture bin (7), and the other end of the stem cell conveying pipeline (6) is arranged on the stem cell sample container (5);
in the closed state of the extraction cover plate (2), the extraction probe (4) is positioned above the stem cell sample container (5).
2. A stem cell collection and extraction device according to claim 1, further comprising a stem cell delivery drive (8); the stem cell conveying driving piece (8) is arranged on the stem cell culture bin (7); stem cell samples driven by a stem cell conveying driving piece (8) pass through a stem cell conveying pipeline (6) from a stem cell culture bin (7) to reach the stem cell sample container (5).
3. A stem cell collecting and extracting device according to claim 1, characterized in that the extracting probe (4) is detachably arranged on the extracting claw (3).
4. A stem cell collecting and extracting device according to claim 1, wherein the extracting claw (3) comprises an extracting claw mounting seat (9), a sliding seat (11) and an extracting probe mounting rod (12); the extracting claw mounting seat (9) is arranged on the extracting cover plate (2); the sliding seat (11) is arranged on the extracting claw mounting seat (9); the extraction probe mounting rod (12) is arranged on the sliding seat (11) in a sliding way; the extraction probe (4) is arranged at one end of the extraction probe mounting rod (12) close to the stem cell sample container (5).
5. A stem cell collecting and extracting device according to claim 4, wherein the extracting probe mounting bar (12) is provided as a threaded bar; the threaded rod is in threaded connection with the sliding seat (11); the extraction probe (4) is arranged at one end of the threaded rod close to the stem cell sample container (5).
6. A stem cell collecting and extracting device according to claim 5, wherein the extracting probe mounting bar (12) is provided with a driving member (13); the extraction probe mounting rod (12) driven by the driving piece (13) is rotatably arranged relative to the sliding seat (11).
7. A stem cell harvesting and extraction apparatus according to claim 4, further comprising an extraction grip (10) and a connecting rod (14); the extraction gripper (10) is rotatably arranged on the extraction gripper mounting seat (9); one end of the connecting rod (14) is rotatably arranged on the extraction gripper (10), and the other end of the connecting rod (14) is rotatably arranged on the sliding seat (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321063887.XU CN219991584U (en) | 2023-05-06 | 2023-05-06 | Stem cell collection and extraction equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202321063887.XU CN219991584U (en) | 2023-05-06 | 2023-05-06 | Stem cell collection and extraction equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219991584U true CN219991584U (en) | 2023-11-10 |
Family
ID=88604540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202321063887.XU Active CN219991584U (en) | 2023-05-06 | 2023-05-06 | Stem cell collection and extraction equipment |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219991584U (en) |
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2023
- 2023-05-06 CN CN202321063887.XU patent/CN219991584U/en active Active
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