CN219907589U - Gene sequencing instrument sample pretreatment structure - Google Patents
Gene sequencing instrument sample pretreatment structure Download PDFInfo
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- CN219907589U CN219907589U CN202320644870.7U CN202320644870U CN219907589U CN 219907589 U CN219907589 U CN 219907589U CN 202320644870 U CN202320644870 U CN 202320644870U CN 219907589 U CN219907589 U CN 219907589U
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- fixedly connected
- wall
- sample
- gene sequencing
- sequencing instrument
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- 238000012163 sequencing technique Methods 0.000 title claims abstract description 25
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 23
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 65
- 238000003756 stirring Methods 0.000 claims abstract description 3
- 238000007790 scraping Methods 0.000 claims abstract 5
- 239000012530 fluid Substances 0.000 claims description 7
- 238000005192 partition Methods 0.000 claims description 7
- 238000000926 separation method Methods 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 12
- 238000005406 washing Methods 0.000 abstract description 11
- 238000000605 extraction Methods 0.000 abstract description 7
- 230000003749 cleanliness Effects 0.000 abstract description 5
- 230000008878 coupling Effects 0.000 abstract description 3
- 238000010168 coupling process Methods 0.000 abstract description 3
- 238000005859 coupling reaction Methods 0.000 abstract description 3
- 230000008859 change Effects 0.000 description 9
- 238000004140 cleaning Methods 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 230000007774 longterm Effects 0.000 description 5
- 238000007781 pre-processing Methods 0.000 description 5
- 230000032683 aging Effects 0.000 description 4
- 238000001712 DNA sequencing Methods 0.000 description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 description 2
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 description 2
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- 108020004414 DNA Proteins 0.000 description 1
- 108091036333 Rapid DNA Proteins 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 229940104302 cytosine Drugs 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000012268 genome sequencing Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 229940113082 thymine Drugs 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model relates to the technical field of sample processing and discloses a sample pretreatment structure of a gene sequencing instrument, which comprises a crushing box, wherein the bottom of the crushing box is fixedly connected with a motor, an output shaft of the motor is fixedly connected with a rotating shaft through a coupling, the outer wall of the rotating shaft is fixedly connected with a stirring rod, the outer wall of the rotating shaft is fixedly connected with a connecting frame, one end of the connecting frame is fixedly connected with a scraping plate, one side of the crushing box is fixedly connected with a water tank, the top of the crushing box is fixedly connected with a water pump, the water inlet of the water pump is fixedly connected with a water inlet pipe, and the water outlet of the water pump is fixedly connected with a water outlet pipe. This gene sequencing instrument sample pretreatment structure can strike off the sample that adheres to on broken incasement wall when handling the sample, reduces the sample and adheres to, accomplishes simultaneously after the sample handling through the inside washing liquid extraction of water tank into broken incasement to wash its inside to improve broken incasement portion's cleanliness, be convenient for later stage use simultaneously.
Description
Technical Field
The utility model relates to the technical field of sample treatment, in particular to a sample pretreatment structure of a gene sequencing instrument.
Background
DNA sequencing refers to analysis of the base sequence of a specific DNA fragment, i.e., the arrangement of adenine, thymine, cytosine and guanine, and the advent of rapid DNA sequencing methods has greatly driven the research and discovery of biology and medicine, and in basic biological research and in numerous fields of application, such as diagnostics, biotechnology, forensic biology, biosystems, knowledge of DNA sequences has become an indispensable knowledge, and rapid sequencing speeds with modern DNA sequencing techniques have been helpful in achieving sequencing of complete DNA sequences, or multiple types of genome sequencing and complete DNA sequences of many species including human genomes and many other animal, plant and microbial species, generally require disruption, washing, separation, etc. of samples prior to gene sequencing.
In Chinese patent utility model, for example: CN202022380146.7, a gene sequencing instrument sample preprocessing device, belongs to sample processing technology field, including broken case, broken case bottom is provided with the conveyer pipe, conveyer pipe one end is provided with the separator box, broken incasement portion is provided with broken washing mechanism, the separator box inside is provided with separating mechanism, broken washing mechanism is including setting up a plurality of baffles in broken incasement portion, broken incasement portion is located the baffle bottom and is provided with the head rod, the head rod outside is provided with a plurality of broken balls, a plurality of broken ball surfaces all are provided with first scraper blade, head rod bottom is provided with the pivot. The utility model has reasonable structure, can effectively crush, wash, separate and the like the cell substances, ensures that the cell substances are more fully crushed, improves the treatment efficiency of the sample, and further accelerates the working efficiency.
The following problems exist in the prior art:
1. the sample is cleaned after being processed, and meanwhile, the sample adhered to the inner wall cannot be scraped, so that the cleaning is unchanged;
2. the inner structure is inconvenient to disassemble after long-term use, so that the inner structure cannot be replaced and maintained.
Disclosure of Invention
(one) solving the technical problems
Aiming at the defects of the prior art, the utility model provides a sample pretreatment structure of a gene sequencing instrument, which has the advantages of convenient cleaning and the like and solves the problems in the background art.
(II) technical scheme
In order to achieve the aim of convenient cleaning, the utility model provides the following technical scheme: the utility model provides a gene sequencing instrument sample preprocessing structure, includes broken case, the bottom fixedly connected with motor of broken case, the output shaft of motor passes through shaft coupling fixedly connected with pivot, the outer wall fixedly connected with puddler of pivot, the outer wall fixedly connected with link of pivot, the one end fixedly connected with scraper blade of link, one side fixedly connected with water tank of broken case.
The top fixedly connected with water pump of broken case, the water inlet fixedly connected with inlet tube of water pump, the delivery port fixedly connected with outlet pipe of water pump, the one end fixedly connected with shower nozzle of outlet pipe, the front swing joint of broken case has sealing door, can strike off the sample that adheres to on broken incasement wall when handling the sample, reduces the sample and adheres to, accomplishes the sample simultaneously after handling through taking into broken incasement with the inside washing liquid extraction of water tank to wash its inside to improve broken incasement portion's cleanliness, be convenient for later stage use simultaneously.
Preferably, the inside wall fixedly connected with locating piece of broken case, the inner wall swing joint of locating piece has the division board, the bottom fixedly connected with fixture block of division board, the draw-in groove has been seted up to the inner wall of locating piece, and the user dismouting to the division board to can clean or change the division board, reduce long-term use division board and damage ageing condition, and avoid the inconvenient change that causes simultaneously of dismouting, and effectively improve the effect of using, and further satisfied the user demand.
Preferably, the bottom of the crushing box is fixedly connected with a guide pipe, and one end of the guide pipe is fixedly connected with a separation box, so that the crushed sample is conveniently guided into the separation box for treatment.
Preferably, one side fixedly connected with of broken case holds the fluid reservoir, and the top of holding the fluid reservoir is provided with the charge door, and the inner wall swing joint of charge door has the stopper, the bottom fixedly connected with drain pipe of holding the fluid reservoir, and one end and one side fixedly connected of broken case of drain pipe are convenient for carry out reinforced in the fluid reservoir.
Preferably, the water filling port is formed in the top of the water tank, and the plug is movably connected to the inner wall of the water filling port, so that water can be filled in the water tank, and the water quantity is not enough.
Preferably, the scraper blade passes through link and pivot fixed connection, and the scraper blade is silica gel scraper blade, can avoid the scraper blade to cause when the broken incasement wall of clearance to cut and scratch, and improves the life of scraper blade, reduces wearing and tearing.
Preferably, one end of the water inlet pipe is fixedly connected with the top of the water tank, and the outer wall of the water inlet pipe is fixedly connected with a pipe clamp, so that water in the water tank is conveniently collected and guided into the crushing box for cleaning.
(III) beneficial effects
Compared with the prior art, the utility model provides a sample pretreatment structure of a gene sequencing instrument, which has the following beneficial effects:
1. this gene sequencing instrument sample preprocessing structure through link, scraper blade, water tank, water pump, inlet tube, outlet pipe and shower nozzle, can strike off the sample that adheres to on broken incasement wall when handling the sample, reduces the sample and adheres to, washs its inside through the washing liquid extraction into broken incasement with the inside washing liquid extraction of water tank after accomplishing sample treatment simultaneously to improve broken incasement portion's cleanliness, be convenient for later stage use simultaneously.
2. This gene sequencing instrument sample preprocessing structure, through locating piece, division board, fixture block and draw-in groove, the person of facilitating the use dismouting to the division board to can clean or change to the division board, reduce long-term use division board and appear damaging ageing condition, and avoid the inconvenient change that causes of dismouting simultaneously, and effectively improve the effect of using, and further satisfied the user demand.
Drawings
FIG. 1 is a schematic view of the present utility model in a front cross-section;
FIG. 2 is a schematic elevational view of the present utility model;
FIG. 3 is an enlarged view of the utility model at A in FIG. 1;
FIG. 4 is a schematic view of the structure of the partition plate of the present utility model;
fig. 5 is a schematic view of the positioning block structure of the present utility model.
In the figure: 1. a crushing box; 2. a conduit; 3. a separation box; 4. a motor; 5. a rotating shaft; 6. a stirring rod; 7. a connecting frame; 8. a scraper; 9. a liquid container; 10. a liquid outlet pipe; 11. a water tank; 12. a water pump; 13. a water inlet pipe; 14. a water outlet pipe; 15. a spray head; 16. sealing the door; 17. a positioning block; 18. a partition plate; 19. a clamping block; 20. a clamping groove.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Example 1
The preferred embodiment of the sample pretreatment structure of the gene sequencing instrument provided by the utility model is shown in fig. 1 to 5: the utility model provides a gene sequencing instrument sample preprocessing structure, includes broken case 1, the bottom fixedly connected with motor 4 of broken case 1, and shaft coupling fixedly connected with pivot 5 is passed through to the output shaft of motor 4, and the outer wall fixedly connected with puddler 6 of pivot 5, the outer wall fixedly connected with link 7 of pivot 5, the one end fixedly connected with scraper blade 8 of link 7, one side fixedly connected with water tank 11 of broken case 1.
The top fixedly connected with water pump 12 of broken case 1, the water inlet fixedly connected with inlet tube 13 of water pump 12, the delivery port fixedly connected with outlet pipe 14 of water pump 12, the one end fixedly connected with shower nozzle 15 of outlet pipe 14, the front swing joint of broken case 1 has sealing door 16, can strike off the sample that adheres to on broken case 1 inner wall when handling the sample, reduce the sample and adhere to, accomplish simultaneously after the sample handles through the washing liquid extraction with the inside of water tank 11 into broken incasement 1 to wash its inside, thereby improve broken incasement portion's cleanliness, be convenient for later use simultaneously.
In this embodiment, the inside wall fixedly connected with locating piece 17 of broken case 1, the inner wall swing joint of locating piece 17 has division board 18, the bottom fixedly connected with fixture block 19 of division board 18, draw-in groove 20 has been seted up to the inner wall of locating piece 17, the user dismouting to division board 18, thereby can clean or change division board 18, reduce long-term use division board 18 and damage ageing's condition, and avoid the dismouting inconvenient change that causes simultaneously, and effectively improve the effect of use, and further satisfied the user demand.
Example 2
On the basis of example 1, a preferred embodiment of the sample pretreatment structure of the gene sequencing instrument according to the present utility model is shown in fig. 1 to 5: the bottom fixedly connected with pipe 2 of broken case 1, the one end fixedly connected with separator tank 3 of pipe 2 is convenient for make the sample after the breakage guide to the separator tank 3 in handle.
In this embodiment, one side fixedly connected with flourishing liquid pot 9 of broken case 1, and flourishing liquid pot 9's top is provided with the charge door, and the inner wall swing joint of charge door has the stopper, flourishing liquid pot 9's bottom fixedly connected with drain pipe 10, and one end and one side fixedly connected with broken case 1 of drain pipe 10 are convenient for carry out reinforced in the flourishing liquid pot 9.
Further, the water filling port is formed in the top of the water tank 11, and the plug is movably connected to the inner wall of the water filling port, so that water can be filled into the water tank 11, and the water quantity is not enough.
Further, scraper 8 passes through link 7 and pivot 5 fixed connection, and scraper 8 is silica gel scraper blade, can avoid scraper 8 to cause when the broken case 1 inner wall of clearance to cut and scratch, and improves scraper 8's life, reduces wearing and tearing.
In addition, one end of the water inlet pipe 13 is fixedly connected with the top of the water tank 11, and the outer wall of the water inlet pipe 13 is fixedly connected with a pipe clamp, so that water in the water tank 11 is conveniently collected and guided into the crushing box 1 for cleaning.
When the utility model is used, when needs wash crushing case 1 inside, can start water pump 12 and make the water in inlet tube 13 extraction water tank 11 and guide outlet pipe 14 in spouting the work of washing to crushing case 1 inside by shower nozzle 15 again, simultaneously motor 4 operation drive pivot 5 now, and thereby make link 7 drive scraper blade 8 rotatory clearance to crushing case 1 inner wall, reduce the adhesion of sample, and improve cleaning performance simultaneously, when needs dismantle split plate 18, can open sealing door 16, pull out split plate 18 from locating piece 17 make fixture block 19 and draw-in groove 20 separation can, the user of being convenient for carries out dismouting change to a plurality of split plates 18.
To sum up, this gene sequencing instrument sample pretreatment structure can strike off the sample that adheres to on broken case 1 inner wall when handling the sample, reduces the sample and adheres to, and the back is handled to the completion sample simultaneously is through taking the inside washing liquid extraction of water tank 11 into broken incasement 1 to its inside washing to improve broken incasement portion's cleanliness, the person of facilitating the use dismouting to partition plate 18, thereby can clean or change partition plate 18, reduce long-term use partition plate 18 and appear damaging ageing's condition, and avoid the inconvenient change that causes of dismouting simultaneously.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. The utility model provides a gene sequencing instrument sample pretreatment structure, includes broken case (1), its characterized in that: the bottom of the crushing box (1) is fixedly connected with a motor (4), an output shaft of the motor (4) is fixedly connected with a rotating shaft (5) through a coupler, the outer wall of the rotating shaft (5) is fixedly connected with a stirring rod (6), the outer wall of the rotating shaft (5) is fixedly connected with a connecting frame (7), one end of the connecting frame (7) is fixedly connected with a scraping plate (8), and one side of the crushing box (1) is fixedly connected with a water tank (11);
the top fixedly connected with water pump (12) of broken case (1), the water inlet fixedly connected with inlet tube (13) of water pump (12), the delivery port fixedly connected with outlet pipe (14) of water pump (12), the one end fixedly connected with shower nozzle (15) of outlet pipe (14), the front swing joint of broken case (1) has sealing door (16).
2. The sample pretreatment structure of a gene sequencing instrument according to claim 1, wherein: the crushing box is characterized in that a positioning block (17) is fixedly connected to the inner side wall of the crushing box (1), a partition plate (18) is movably connected to the inner wall of the positioning block (17), a clamping block (19) is fixedly connected to the bottom of the partition plate (18), and a clamping groove (20) is formed in the inner wall of the positioning block (17).
3. The sample pretreatment structure of a gene sequencing instrument according to claim 1, wherein: the bottom of broken case (1) fixedly connected with pipe (2), the one end fixedly connected with separation case (3) of pipe (2).
4. The sample pretreatment structure of a gene sequencing instrument according to claim 1, wherein: one side fixedly connected with flourishing fluid reservoir (9) of broken case (1), and the top of flourishing fluid reservoir (9) is provided with the charge door, and the inner wall swing joint of charge door has the stopper, the bottom fixedly connected with drain pipe (10) of flourishing fluid reservoir (9), and one end and one side fixedly connected with broken case (1) of drain pipe (10).
5. The sample pretreatment structure of a gene sequencing instrument according to claim 1, wherein: a water filling port is formed in the top of the water tank (11), and a plug is movably connected to the inner wall of the water filling port.
6. The sample pretreatment structure of a gene sequencing instrument according to claim 1, wherein: the scraping plate (8) is fixedly connected with the rotating shaft (5) through the connecting frame (7), and the scraping plate (8) is a silica gel scraping plate.
7. The sample pretreatment structure of a gene sequencing instrument according to claim 1, wherein: one end of the water inlet pipe (13) is fixedly connected with the top of the water tank (11), and the outer wall of the water inlet pipe (13) is fixedly connected with a pipe clamp.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320644870.7U CN219907589U (en) | 2023-03-28 | 2023-03-28 | Gene sequencing instrument sample pretreatment structure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202320644870.7U CN219907589U (en) | 2023-03-28 | 2023-03-28 | Gene sequencing instrument sample pretreatment structure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN219907589U true CN219907589U (en) | 2023-10-27 |
Family
ID=88463254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202320644870.7U Active CN219907589U (en) | 2023-03-28 | 2023-03-28 | Gene sequencing instrument sample pretreatment structure |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN219907589U (en) |
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2023
- 2023-03-28 CN CN202320644870.7U patent/CN219907589U/en active Active
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