CN218824325U - Detection module - Google Patents

Detection module Download PDF

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Publication number
CN218824325U
CN218824325U CN202222948093.3U CN202222948093U CN218824325U CN 218824325 U CN218824325 U CN 218824325U CN 202222948093 U CN202222948093 U CN 202222948093U CN 218824325 U CN218824325 U CN 218824325U
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detection
module
assembly
sample
needle
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CN202222948093.3U
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许行尚
杰弗瑞·陈
戴光韬
郭金龙
胡统号
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Suzhou Aikeruite Biomedical Technology Co ltd
Nanjing Lanyu Biological Technology Co Ltd
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Suzhou Aikeruite Biomedical Technology Co ltd
Nanjing Lanyu Biological Technology Co Ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

The utility model discloses a detection module, which comprises a detection cavity, wherein a detection shading cover plate is arranged above the detection cavity, a detection disc is arranged in the detection cavity, a plurality of detection reaction cup positions are correspondingly arranged on the detection disc, and the detection reaction cup positions are used for placing reaction cups to be detected; a Photomultiplier (PMT) is arranged on the side surface of the detection cavity and is used for detecting the reaction cup and collecting optical signals; and a detection needle assembly is also arranged above the detection cavity and comprises a detection waste liquid needle and a detection substrate needle. The detection module improves the detection accuracy, has a simple and compact structure, and reduces the volume.

Description

Detection module
Technical Field
The utility model belongs to the technical field of medical equipment, especially, relate to a detection module for full-automatic chemiluminescence immunoassay appearance.
Background
The mainstream chemiluminescence product in the market needs to adopt serum or plasma as a detection sample, can not support direct and automatic detection of a whole blood sample, has long first sample report time and long total diagnosis time, hardly meets the requirement of detection turnover time, has long total waiting time, can aggravate the pain of a patient, easily causes the conflict emotion of family members or the patient, and is not beneficial to the treatment of subsequent patients.
Chinese patent document CN209148549U discloses a chemiluminescence detection apparatus including a centrifugal disk and an optical detection module, and further including: a body formed with a cavity having an opening; the cover body is used for covering the cavity in an opening and closing manner and controlling whether the opening is closed or not; the rotating shaft is arranged in the cavity, and the centrifugal disc is suitable for being fixed on the rotating shaft and is positioned in the cavity; the optical detection module is arranged at the lower part of the centrifugal disc in the cavity, and the detection position of the centrifugal disc corresponds to the optical detection module up and down; the motor drives the rotating shaft to rotate; and the lifting module is used for controlling the lifting of the optical detection module. The chemiluminescence detection device disclosed in the technical scheme still has defects in practical application, and is large in size and low in detection accuracy.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a detection module, improved the detection accuracy, simple structure, and compact structure has reduced the volume.
In order to solve the technical problem, the utility model adopts the technical scheme that the detection module comprises a detection cavity, a detection shading cover plate is arranged above the detection cavity, a detection disc is arranged in the detection cavity, a plurality of detection reaction cup positions are correspondingly arranged on the detection disc, and the detection reaction cup positions are used for placing reaction cups to be detected; a Photomultiplier (PMT) is arranged on the side surface of the detection cavity and is used for detecting the reaction cup and collecting optical signals; and a detection needle assembly is also arranged above the detection cavity and comprises a detection waste liquid needle and a detection substrate needle.
Preferably, it is rotatory by detecting a set rotating assembly drive to detect the dish, it is including detecting a set rotating electrical machines to detect a set rotating electrical machines, it connects and detects a set rotating electrical machines action wheel to detect a set rotating electrical machines action wheel, it drives to detect a set rotating electrical machines from the driving wheel rotation through detecting a set rotating electrical machines belt to detect a set rotating electrical machines action wheel, it connects from the driving wheel to detect a set rotating electrical machines detect the dish.
Preferably, the detection needle assembly is driven by a detection needle assembly up-and-down movement assembly to move up and down, the detection needle assembly up-and-down movement assembly comprises a detection needle assembly up-and-down movement motor, the detection needle assembly up-and-down movement motor is connected with a detection needle assembly up-and-down movement screw nut assembly, the detection needle assembly up-and-down movement screw nut assembly is fixedly connected with a detection needle assembly mounting bracket of the detection needle assembly and a detection needle assembly up-and-down movement sliding block, and the detection needle assembly up-and-down movement sliding block moves up and down along a detection needle assembly up-and-down movement sliding rail.
Preferably, the detection shading cover plate is provided with a manipulator operation position, and a detection plate rotation limiting optocoupler is arranged on the side surface of the driven wheel of the detection plate rotating motor and used for monitoring the rotation angle of the detection plate; the detection plate is provided with a plurality of detection reaction cup positions which are used as reaction cup inlet and outlet positions, bottom adding and detection positions and waste liquid discharge positions.
Preferably, the detection module is suitable for a full-automatic chemiluminescence immunoassay analyzer, which comprises a functional main body module arranged on a base, wherein the functional main body module comprises a sampling needle module, a reaction cup loading module, a reagent disc module, a diluting module, a shaking module, an incubation and reaction module, a magnetic separation cleaning module, a detection module and a sample management module which is mutually independent from the functional main body module.
Preferably, the reaction cup loading module, the reagent tray module, the shaking module, the magnetic separation cleaning module and the detection module are all arranged around the incubation and reaction module, wherein the dilution module is arranged on the side surface of the sampling needle module, and the magnetic separation cleaning module and the detection module are arranged adjacently; the functional main body module further comprises a mechanical arm module, and a mechanical arm device in the mechanical arm module is used for transferring reaction cups positioned in the reaction cup loading module, the shaking module, the magnetic separation cleaning module and the detection module.
Compared with the prior art, the utility model discloses a detection module has improved the detection accuracy, simple structure, and compact structure has reduced the volume.
Drawings
The following is a more detailed description of embodiments of the present invention with reference to the accompanying drawings:
fig. 1 is a schematic diagram of an overall three-dimensional structure of a full-automatic chemiluminescence immunoassay analyzer;
FIG. 2 is a schematic diagram of the overall three-dimensional structure of the full-automatic chemiluminescence immunoassay analyzer of the present invention;
FIG. 3 is a schematic diagram of the overall top view structure of the full-automatic chemiluminescence immunoassay analyzer of the invention;
fig. 4 is a schematic perspective view of the functional body module;
FIG. 5 is a schematic top view of the functional body module;
FIG. 6.1 is a schematic perspective view of the detection module;
FIG. 6.2 is a schematic perspective view of the detection module (with the detection light-shielding cover removed);
FIG. 6.3 is a schematic side view of the detection module;
FIG. 6.4 is a schematic top view of the detection module;
FIG. 6.5 is a schematic cross-sectional view of the detection module;
FIG. 6.6 is a schematic bottom structure of the detection module;
wherein: 1-a base; 2-a functional body module; 3-a sampling needle module, 4-a reaction cup loading module, 5-a reagent tray module, 6-a sample management module, 601-a sample loading and unloading module, 602-a sample transmission module, 603-a sample sampling carrying module, 604-a sample rack, 7-a shaking module, 8-an incubation and reaction module, 9-a magnetic separation cleaning module, 10-a detection module, 1001-a detection cavity, 1002-a detection shading cover plate, 100201-a manipulator operation position, 1003-a detection tray, 100301-a detection reaction cup position, 100302-a reaction cup inlet position, 100303-a substrate and detection position, 100304-a waste liquid discharge position, 1004-a photomultiplier PMT, a detection needle assembly, 100501-a detection waste liquid needle, 100502-detection substrate needle, 1006-detection disc rotating assembly, 100601-detection disc rotating motor, 100602-detection disc rotating motor driving wheel, 100603-detection disc rotating motor belt, 100604-detection disc rotating motor driven wheel, 100605-detection disc rotating limiting optical coupler, 1007-detection needle assembly up-and-down movement assembly, 100701-detection needle assembly up-and-down movement motor, 100702-detection needle assembly up-and-down movement sliding block, 100703-detection needle assembly up-and-down movement sliding rail, 1008-detection needle assembly up-and-down movement screw nut assembly, 1009-detection needle assembly mounting bracket, 11-dilution module, 12-manipulator module, 1201, 1202, 1203-manipulator device.
Detailed Description
In order to deepen the understanding of the present invention, the present invention will be described in further detail with reference to the following embodiments, which are only used for explaining the present invention, and are not limited to the protection scope of the present invention.
The detection module 10 of this embodiment includes a detection chamber 1001, as shown in fig. 6.1, a detection light-shielding cover plate 1002 is disposed above the detection chamber 1001, a detection tray 1003 is disposed in the detection chamber 1001, a plurality of detection reaction cup positions 100301 are correspondingly disposed on the detection tray 1003, and the detection reaction cup positions 100301 are used for placing reaction cups to be detected; a photomultiplier tube PMT 1004 is arranged on the side surface of the detection cavity 1001 and is used for detecting the reaction cup and collecting optical signals; a detection needle assembly 1005 is further disposed above the detection chamber 1001, and the detection needle assembly 1005 includes a detection waste liquid needle 100501 and a detection substrate needle 100502.
As shown in fig. 6.2-6.6, the detection tray 1003 is driven by a detection tray rotating assembly 1006 to rotate, the detection tray rotating assembly 1006 includes a detection tray rotating motor 100601, the detection tray rotating motor 100601 is connected to a detection tray rotating motor driving wheel 100602, the detection tray rotating motor driving wheel 100602 drives the detection tray rotating motor driven wheel 100604 to rotate through a detection tray rotating motor belt 100603, and the detection tray rotating motor driven wheel 100604 is connected to the detection tray 1003.
The detection needle assembly 1005 is driven by the detection needle assembly up-and-down movement assembly 1007 to move up and down, the detection needle assembly up-and-down movement assembly 1007 comprises a detection needle assembly up-and-down movement motor 100701, the detection needle assembly up-and-down movement motor 100701 is connected with the detection needle assembly up-and-down movement screw nut assembly 1008, the detection needle assembly up-and-down movement screw nut assembly 1008 is fixedly connected with a detection needle assembly mounting bracket 1009 of the detection needle assembly 1005 and a detection needle assembly up-and-down movement slider 100702, wherein the detection needle assembly up-and-down movement slider 100702 moves up and down along a detection needle assembly up-and-down movement slide rail 100703, and the slider and the slide rail are matched to enable the detection needle assembly 1005 to move up and down.
The detection shading cover plate 1002 is provided with a manipulator operation position 100201, and a detection disc rotation limiting optocoupler 100605 is arranged on the side surface of a detection disc rotating motor driven wheel 100604 and used for monitoring the rotation angle of the detection disc 1003; the detection tray 1003 is provided with a plurality of detection reaction cup positions 100301 as a reaction cup inlet/outlet position 100302, a bottom adding and detection position 100303 and a waste liquid discharge position 100304.
The first manipulator device 1201 clamps the reaction cup into the detection tray 1003 of the detection module 10, the reaction cup rotates to a position below the detection substrate needle 100502, after the reaction substrate is added into the detection substrate needle 100502, the photomultiplier tube PMT 1004 detects the reaction cup, and collects an optical signal; after detection, the reaction cup rotates to a position below the detection waste liquid needle 100501, and the detection waste liquid needle 100501 moves downwards to suck and discharge waste liquid; the first manipulator device 1201 clamps and discards the reaction cup, and the detection light-shielding cover plate 1002 provides a dark environment required by detection.
The detection module 10 of the present embodiment is suitable for a full-automatic chemiluminescence immunoassay analyzer, as shown in fig. 1-5, the full-automatic chemiluminescence immunoassay analyzer comprises a functional main body module 2 arranged on a base 1, the functional main body module 2 comprises a sampling needle module 3, a reaction cup loading module 4, a reagent disk module 5, a dilution module 11, a shaking module 7, an incubation and reaction module 8, a magnetic separation cleaning module 9 and a detection module 10, and further comprises a sample management module 6 mutually independent from the functional main body module 2, the sample management module 6 comprises a sample loading and unloading assembly 601, a sample transmission assembly 602 and a sample sampling carrying assembly 603, wherein the sample loading and unloading assembly 601 is used for loading and unloading a sample rack 604, and the sample transmission assembly 602 is used for transferring the sample rack 604 between the sample loading and unloading assembly 601 and the sample sampling carrying assembly 603; the sampling needle module 3 is used to add the sample at the location of the sample sampling carrier assembly 603 to the incubation and reaction module 8.
As shown in fig. 3, the sample management module 6 is disposed adjacent to the L-shaped semi-enclosed base 1, and the sample sampling carrier assembly 603 is disposed adjacent to the sampling needle module 3; the reaction cup loading module 4, the reagent tray module 5, the shaking module 7, the magnetic separation cleaning module 9 and the detection module 10 are all arranged around the incubation and reaction module 8, wherein the dilution module 11 is arranged on the side surface of the sampling needle module 3, and the magnetic separation cleaning module 9 and the detection module 10 are arranged adjacently; the functional body module 2 further comprises a manipulator module 12, and manipulator devices 1201, 1202 and 1203 (three sets of manipulator devices are provided in the manipulator module 12, and those skilled in the art can increase or decrease the number of the manipulator devices according to the needs of the instrument) in the manipulator module 12 are used for transferring the cuvettes in the cuvette loading module 4, the shaking module 7, the magnetic separation and cleaning module 9 and the detection module 10.
It should be noted that, for the manipulator devices in the cuvette loading module 4, the reagent disk module 5, the shaking module 7, the incubation and reaction module 8, the magnetic separation cleaning module 9, the dilution module 11, the sampling needle module 3, the sample management module 6 and the manipulator module 12 in this embodiment, no updated improvement is made, and those skilled in the art can adopt the existing method to realize that they are assembled with the detection module 10 in this embodiment and realize that the three-layer structure arrangement fully utilizes the three-dimensional space, reduces the transverse size of the analyzer, reduces the volume, has a compact structure, and improves the cleaning efficiency.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (6)

1. A detection module is characterized by comprising a detection cavity, wherein a detection shading cover plate is arranged above the detection cavity, a detection disc is arranged in the detection cavity, a plurality of detection reaction cup positions are correspondingly arranged on the detection disc, and the detection reaction cup positions are used for placing reaction cups to be detected; a Photomultiplier (PMT) is arranged on the side surface of the detection cavity and is used for detecting the reaction cup and collecting optical signals; and a detection needle assembly is also arranged above the detection cavity and comprises a detection waste liquid needle and a detection substrate needle.
2. The detection module of claim 1, wherein the detection plate is driven to rotate by a detection plate rotating assembly, the detection plate rotating assembly comprises a detection plate rotating motor, the detection plate rotating motor is connected with a detection plate rotating motor driving wheel, the detection plate rotating motor driving wheel drives a detection plate rotating motor driven wheel to rotate through a detection plate rotating motor belt, and the detection plate rotating motor driven wheel is connected with the detection plate.
3. The detection module according to claim 2, wherein the detection needle assembly is driven by a detection needle assembly up-and-down movement assembly to move up and down, the detection needle assembly up-and-down movement assembly comprises a detection needle assembly up-and-down movement motor, the detection needle assembly up-and-down movement motor is connected with the detection needle assembly up-and-down movement screw nut assembly, the detection needle assembly up-and-down movement screw nut assembly is fixedly connected with the detection needle assembly mounting bracket of the detection needle assembly and the detection needle assembly up-and-down movement slider, and the detection needle assembly up-and-down movement slider moves up and down along the detection needle assembly up-and-down movement slide rail.
4. The detection module according to claim 3, wherein the detection light-shielding cover plate is provided with a manipulator operation position, and a detection disc rotation limiting optical coupler is arranged on the side surface of a driven wheel of the detection disc rotating motor and used for monitoring the rotation angle of the detection disc; the detection plate is provided with a plurality of detection reaction cup positions which are used as reaction cup inlet and outlet positions, bottom adding and detection positions and waste liquid discharge positions.
5. The detection module according to any one of claims 1 to 4, which is suitable for a full-automatic chemiluminescent immunoassay analyzer comprising a functional body module disposed on a base, wherein the functional body module comprises a sampling needle module, a reaction cup loading module, a reagent disk module, a dilution module, a shaking module, an incubation and reaction module, a magnetic separation and cleaning module and a detection module, and a sample management module independent from the functional body module, the sample management module comprises a sample loading and unloading assembly, a sample conveying assembly and a sample sampling carrying assembly, wherein the sample loading and unloading assembly is used for loading and unloading a sample rack, and the sample conveying assembly is used for transferring the sample rack between the sample loading and unloading assembly and the sample sampling carrying assembly; the sampling needle module is used to add a sample at the location of the sample sampling carrier assembly to the incubation and reaction module.
6. The detection module of claim 5, wherein the cuvette loading module, reagent tray module, shaking module, magnetic separation washing module and detection module are all arranged around the incubation and reaction module, wherein the dilution module is disposed at a side of the sampling needle module, and the magnetic separation washing module and the detection module are disposed adjacent to each other; the functional main body module further comprises a mechanical arm module, and a mechanical arm device in the mechanical arm module is used for transferring reaction cups positioned in the reaction cup loading module, the shaking module, the magnetic separation cleaning module and the detection module.
CN202222948093.3U 2022-11-07 2022-11-07 Detection module Active CN218824325U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222948093.3U CN218824325U (en) 2022-11-07 2022-11-07 Detection module

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222948093.3U CN218824325U (en) 2022-11-07 2022-11-07 Detection module

Publications (1)

Publication Number Publication Date
CN218824325U true CN218824325U (en) 2023-04-07

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222948093.3U Active CN218824325U (en) 2022-11-07 2022-11-07 Detection module

Country Status (1)

Country Link
CN (1) CN218824325U (en)

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