CN218885938U - Magnetic separation cleaning module - Google Patents
Magnetic separation cleaning module Download PDFInfo
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- CN218885938U CN218885938U CN202222948056.2U CN202222948056U CN218885938U CN 218885938 U CN218885938 U CN 218885938U CN 202222948056 U CN202222948056 U CN 202222948056U CN 218885938 U CN218885938 U CN 218885938U
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- 238000004140 cleaning Methods 0.000 title claims abstract description 168
- 238000007885 magnetic separation Methods 0.000 title claims abstract description 56
- 239000000758 substrate Substances 0.000 claims abstract description 15
- 239000011324 bead Substances 0.000 claims abstract description 6
- 239000000376 reactant Substances 0.000 claims abstract description 5
- 230000033001 locomotion Effects 0.000 claims description 59
- 239000007788 liquid Substances 0.000 claims description 23
- 238000001514 detection method Methods 0.000 claims description 18
- 238000005070 sampling Methods 0.000 claims description 13
- 238000011534 incubation Methods 0.000 claims description 12
- 238000001179 sorption measurement Methods 0.000 claims description 9
- 239000003153 chemical reaction reagent Substances 0.000 claims description 8
- 238000003018 immunoassay Methods 0.000 claims description 8
- 238000010790 dilution Methods 0.000 claims description 5
- 239000012895 dilution Substances 0.000 claims description 5
- 239000007795 chemical reaction product Substances 0.000 claims description 4
- 238000007865 diluting Methods 0.000 claims description 3
- 238000005406 washing Methods 0.000 abstract description 21
- 238000004458 analytical method Methods 0.000 abstract description 3
- 238000010276 construction Methods 0.000 abstract description 3
- 238000000926 separation method Methods 0.000 abstract description 3
- 230000005389 magnetism Effects 0.000 abstract 1
- 238000010586 diagram Methods 0.000 description 6
- 150000001875 compounds Chemical class 0.000 description 5
- 239000006249 magnetic particle Substances 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 239000007791 liquid phase Substances 0.000 description 2
- 238000005191 phase separation Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000012295 chemical reaction liquid Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000012840 feeding operation Methods 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
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Abstract
The utility model discloses a magnetic separation cleaning module, which comprises a chassis, a reaction cup rotating disc and a cleaning needle disc which are arranged from bottom to top in sequence; the magnetic attraction component is arranged on the base plate and used for adsorbing magnetic bead reactants when the reaction cup is cleaned; the reaction cup rotating disc is used for rotating the reaction cup to a preset position, and a plurality of reaction cup positions are arranged on the reaction cup rotating disc; the cleaning needle disc comprises a cleaning needle assembly and a substrate adding needle assembly, and is used for completing the cleaning and substrate adding operation of the reaction cup. This magnetism separation cleaning module carries out three layer construction setting through carrying out chassis, reaction cup rotary disk and washing dial, make full use of cubical space, has reduced the horizontal size of analysis appearance, has reduced the volume, compact structure, and has improved the cleaning efficiency.
Description
Technical Field
The utility model belongs to the technical field of medical equipment, especially, relate to a magnetic separation cleaning module for full-automatic chemiluminescence immunoassay appearance.
Background
The mainstream chemiluminescence product in the market needs to adopt serum or plasma as a detection sample, can not support direct and automatic detection of a whole blood sample, has long first sample report time and long total diagnosis time, hardly meets the requirement of detection turnaround time, has long total waiting time, can aggravate the pain of patients, easily causes the conflicting emotion of family members or patients, and is not favorable for the treatment of follow-up patients.
In an in vitro diagnostic instrument, the magnetic separation cleaning device is used for carrying out solid-liquid phase separation on a magnetic particle compound and a reaction liquid. In order to ensure the purpose of magnetic separation, in the separation process, the magnetic particle compound needs to be injected, mixed and absorbed for a plurality of times to achieve a good separation and cleaning effect, and in the magnetic separation process, a fixed magnet needs to be used to tightly adsorb the magnetic particle compound on the side wall of the reaction cup to prevent the magnetic particle compound from being absorbed when absorbing liquid, so that an accurate test result is obtained.
In chinese patent document CN216369257U, a magnetic separation washing structure is disclosed, magnetic separation washing structure includes the washing pot, and fixed setting is in the magnetic adsorption module of washing pot rotationally sets up inner circle washing dish and outer lane washing dish in the washing pot, and sets up inner circle washing dish with the cleaning unit of outer lane washing dish top, through the theory of operation that adopts inside and outside double circles, with the mode of a plurality of module integration formation washing module, and carry out solid-liquid phase separation through the mode of setting up to inner circle washing dish, outer lane washing dish, magnet circle and cleaning unit's relative position, the magnetic separation washing structure disclosed among the above-mentioned technical scheme, product structure is still complicated, and cleaning efficiency is lower.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a magnetic separation cleaning module, through chassis, reaction cup rotary disk and washing dial, three layer construction sets up, make full use of cubical space, reduced the transverse dimension of analysis appearance, reduced the volume, compact structure, and improved the cleaning efficiency.
In order to solve the technical problem, the technical scheme adopted by the utility model is that the magnetic separation cleaning module comprises a chassis, a reaction cup rotating disc and a cleaning needle disc which are arranged from bottom to top in sequence; the magnetic attraction component is arranged on the base plate and used for adsorbing magnetic bead reactants when the reaction cup is cleaned; the reaction cup rotating disc is used for rotating the reaction cup to a preset position, and a plurality of reaction cup positions are arranged on the reaction cup rotating disc; the cleaning needle disc comprises a cleaning needle assembly and a substrate filling needle assembly which are used for completing the cleaning and substrate filling operation of the reaction cup.
The three-layer structure is arranged, so that the three-dimensional space is fully utilized, the transverse size of the analyzer is reduced, and the structure is compact.
Preferably, the magnetic attraction component comprises a first magnet group and a second magnet group, the first magnet group is used for pre-adsorption, and the second magnet group is used for adsorption of a reaction product and a magnet; the first magnet group and the second magnet group are both located below the reaction cup.
Preferably, the magnetic separation cleaning module comprises a shaking assembly, the shaking assembly is arranged below the chassis, a shaking seat in the shaking assembly extends out of the chassis, and the shaking seat is arranged below a reaction cup position on the reaction cup rotating disc; the shaking-up component comprises a shaking-up motor, and the shaking-up motor drives the eccentric shaft block component to move so as to drive the shaking-up base to shake; the side surface of the shaking seat is provided with a shaking pressure head, and the shaking pressure head is arranged on the chassis through a shaking pressure head bracket.
The shaking component is used for shaking the reaction cup.
Preferably, the shaking seat is connected with a shaking up-and-down motion screw rod nut connecting block, the shaking up-and-down motion screw rod nut connecting block is connected with a shaking up-and-down motion screw rod nut, and a shaking up-and-down motion motor drives the shaking up-and-down motion screw rod nut connecting block to move up and down so as to drive the shaking seat to move up and down; and a shaking groove is arranged on the shaking seat.
When the reaction cup is placed, the bottom of the reaction cup is fixed in the shaking groove.
Preferably, the shaking up-and-down motion screw nut connecting block is at least connected with two shaking seats, and the shaking pressure head is in a semi-spherical shape; the semi-spherical shape has good fitting degree with the top end of the reaction cup, so that the reaction cup is stable when shaken up.
Preferably, the cleaning dial is controlled by a cleaning needle up-and-down movement assembly to move up and down, the cleaning needle up-and-down movement assembly comprises a cleaning needle up-and-down movement motor, and the cleaning needle up-and-down movement motor is connected with the cleaning dial through a cleaning needle up-and-down movement nut connecting piece; the magnetic separation cleaning module is further provided with a guide rod, and the cleaning dial moves up and down along the guide rod.
Preferably, the guide rod is provided with a limiting block at the contact position of the cleaning dial and the cleaning dial supporting plate, and the cleaning dial supporting plate is used for supporting the cleaning dial; the cleaning needle assembly comprises a cleaning needle group, the cleaning needle group comprises a liquid suction needle and a liquid discharge needle, and a cleaning needle group spring is further installed in the cleaning needle group; the limiting block is used for limiting the up-and-down movement of the cleaning dial.
Preferably, the cleaning needle up-and-down movement nut connecting piece is arranged on a cleaning needle up-and-down movement screw rod connected with the cleaning needle up-and-down movement motor; the cleaning needle up-and-down movement motor is positioned above the cleaning needle disc; the reaction cup rotating disc is controlled to rotate by a reaction cup rotating disc motor, and the reaction cup rotating disc motor and the shaking up-and-down motion motor are both positioned below the base plate.
The magnetic separation cleaning module is suitable for a full-automatic chemiluminescence immunoassay analyzer which comprises a functional main body module arranged on a base, wherein the functional main body module comprises a sampling needle module, a reaction cup loading module, a reagent disc module, a diluting module, a shaking module, an incubation and reaction module, a magnetic separation cleaning module and a detection module, and further comprises a sample management module which is mutually independent from the functional main body module.
Preferably, the reaction cup loading module, the reagent tray module, the shaking module, the magnetic separation cleaning module and the detection module are all arranged around the incubation and reaction module, wherein the dilution module is arranged on the side surface of the sampling needle module, and the magnetic separation cleaning module and the detection module are arranged adjacently; the functional main body module further comprises a mechanical arm module, and a mechanical arm device in the mechanical arm module is used for transferring reaction cups positioned in the reaction cup loading module, the shaking module, the magnetic separation cleaning module and the detection module.
Compared with the prior art, the utility model discloses a magnetic separation cleaning module, through chassis, reaction cup rotary disk and washing dial, three layer construction sets up, make full use of cubical space, reduced the transverse dimension of analysis appearance, reduced the volume, compact structure, and improved the cleaning efficiency.
Drawings
The following detailed description is made with reference to the accompanying drawings and embodiments of the present invention:
fig. 1 is a schematic diagram of the overall three-dimensional structure of the full-automatic chemiluminescence immunoassay analyzer of the invention;
FIG. 2 is a schematic diagram of the overall three-dimensional structure of the full-automatic chemiluminescence immunoassay analyzer of the present invention;
FIG. 3 is a schematic diagram of the overall top view structure of the full-automatic chemiluminescence immunoassay analyzer of the invention;
fig. 4 is a schematic perspective view of the functional body module;
FIG. 5 is a schematic top view of the functional body module;
FIG. 6.1 is a schematic perspective view of a magnetic separation cleaning module;
FIG. 6.2 is a side view of the magnetic separation cleaning module of FIG. 6.1;
FIG. 6.3 is a schematic view of a partial magnet assembly of the magnetic separation cleaning module;
FIG. 6.4 is a schematic top view of the magnetic separation cleaning module;
FIG. 6.5 is a schematic view of the bottom structure of the magnetic separation cleaning module;
FIG. 6.6 is a schematic diagram of a side view of the magnetic separation cleaning module of FIG. 6.1;
FIG. 6.7 is a schematic view of a rocking head structure of the magnetic separation cleaning module;
FIG. 6.8 is a first structural diagram of a shaking assembly of the magnetic separation cleaning module;
FIG. 6.9 is a second structural diagram of the shaking assembly of the magnetic separation cleaning module;
FIG. 6.10 is a schematic view of the cleaning needle assembly of the magnetic separation cleaning module;
FIG. 6.11 is a schematic view of the internal structure of the cleaning needle assembly of FIG. 6.10;
wherein: 1-a base; 2-a functional body module; 3-a sampling needle module, 4-a reaction cup loading module, 5-a reagent tray module, 6-a sample management module, 601-a sample loading and unloading component, 602-a sample transmission component, 603-a sample sampling carrying component, 604-a sample frame, 7-a shaking module, 8-an incubation and reaction module, 9-a magnetic separation cleaning module, 901-a chassis, 902-a reaction cup rotating disk, 90201-a reaction cup position, 90202-a reaction cup rotating disk motor, 903-a cleaning needle tray, 90301-a cleaning needle up-and-down movement component, 90302-a cleaning needle up-and-down movement motor, 90303-a cleaning needle up-and-down movement nut connecting piece, 90304-a guide rod, 90305-a limiting block, 90306-cleaning needle up-and-down movement screw rod, 904-magnetic attraction component, 90401-magnet group I, 90402-magnet group II, 905-cleaning needle component, 90501-cleaning needle component, 90502-liquid suction needle, 90503-liquid discharge needle, 90504-cleaning needle group spring, 906-substrate liquid adding needle component, 907-shaking component, 90701-shaking seat, 90702-shaking motor, 90703-eccentric shaft component, 90704-shaking groove, shaking head homogenizing, 909-shaking head support, 9010-shaking screw rod up-and-down movement nut connecting block, 9011-shaking up-and-down movement screw rod nut, 9012-shaking up-and-down movement motor, 9013-cleaning needle dial support plate; 10-detection module, 11-dilution module, 12-manipulator module, 1201, 1202, 1203-manipulator device.
Detailed Description
In order to deepen the understanding of the present invention, the present invention will be described in further detail with reference to the following embodiments, which are only used for explaining the present invention, and are not limited to the protection scope of the present invention.
The magnetic separation cleaning module 9 of this embodiment includes a chassis 901, a reaction cup rotating disc 902 and a cleaning needle disc 903, which are sequentially arranged from bottom to top, as shown in fig. 6.1 to 6.2, and fig. 6.4 to 6.6; a magnetic attraction component 904 is arranged on the base plate 901, and when the reaction cup 13 is cleaned, the magnetic attraction component 904 is used for adsorbing magnetic bead reactants; the reaction cup rotating disc 902 is used for rotating the reaction cup to a preset position, and a plurality of reaction cup positions 90201 are arranged on the reaction cup rotating disc 902; the washing needle 903 comprises a washing needle assembly 905 and a substrate feeding needle assembly 906 for completing the washing and substrate feeding operations of the reaction cup.
The magnetic attraction component 904 comprises a first magnet group 90401 and a second magnet group 90402, as shown in fig. 6.3, the first magnet group 90401 is used for pre-adsorption, and the second magnet group 90402 is used for reaction products and magnet adsorption; the first magnet group 90401 and the second magnet group 90402 are both located below the reaction cup position 90201 (the reaction cup is pre-adsorbed by the first magnet group 90401 and then adsorbed by the second magnet group 90402, the cleaning needle group 90501 performs cleaning action, liquid discharge and liquid addition, and pre-adsorption and secondary adsorption are arranged so that reaction products can be sufficiently adsorbed by the magnets).
As shown in fig. 6.8-6.9, the magnetic separation cleaning module 9 comprises a shaking assembly 907, the shaking assembly 907 is arranged below the chassis 901, wherein a shaking seat 90701 in the shaking assembly 907 extends out of the chassis 901, and the shaking seat 90701 is positioned below a reaction cup position 90201 on the reaction cup rotating disc 902; the shaking-up component 907 comprises a shaking-up motor 90702, and a shaking-up motor 90702 drives the eccentric shaft block component 90703 to move so as to drive the shaking-up base 90701 to shake; the side of the shaking seat 90701 is provided with a shaking head 908, and as shown in fig. 6.7, the shaking head 908 is mounted on the chassis 901 through a shaking head support 909.
The shaking seat 90701 is connected with a shaking up-and-down movement lead screw nut connecting block 9010, the shaking up-and-down movement lead screw nut connecting block 9010 is connected with a shaking up-and-down movement lead screw nut 9011, and a shaking up-and-down movement motor 9012 drives the shaking up-and-down movement lead screw nut connecting block 9010 to move up and down so as to drive the shaking seat 90701 to move up and down; the shaking seat 90701 is provided with a shaking groove 90704.
The shaking up and down movement screw nut connecting block 9010 is at least connected with two shaking up seats, and the shaking up pressure head 908 is in a semispherical shape.
The cleaning needle disc 903 is controlled by a cleaning needle up-and-down movement assembly 90301 to move up and down, the cleaning needle up-and-down movement assembly 90301 comprises a cleaning needle up-and-down movement motor 90302, and the cleaning needle up-and-down movement motor 90302 is connected with the cleaning needle disc 903 through a cleaning needle up-and-down movement nut connecting piece 90303; the magnetic separation cleaning module 9 is further provided with a guide rod 90304, and the cleaning needle disc 903 moves up and down along the guide rod 90304.
A limiting block 90305 is arranged at the contact position of the cleaning dial 903 and the cleaning dial support plate 9013 of the guide rod 90304, and the cleaning dial support plate 9013 is used for supporting the cleaning dial 903; the cleaning needle assembly 905 comprises a cleaning needle group 90501, as shown in fig. 6.10 and 6.11, the cleaning needle group 90501 comprises a liquid suction needle 90502 and a liquid discharge needle 90503, and a cleaning needle group spring 90504 is further installed in the cleaning needle group 90501.
Two guide rods 90304 are arranged on two sides of a mounting seat of a cleaning needle up-and-down movement motor 90302, the guide rods 90304 penetrate through a cleaning needle dial 903, the lower end of the guide rods 90304 is connected with a cleaning needle dial supporting plate 9013, the guide rods 90304 are used for enabling the cleaning needle dial 903 to stably drive a needle set to move up and down, meanwhile, a limiting block 90305 is arranged at the contact position of the cleaning needle dial 903 and the cleaning needle dial supporting plate 9013 of the guide rods 90304, two limiting blocks 90305 are arranged on the bottom surface of the cleaning needle dial 903, the cleaning needle dial 903 plays a physical limiting role when moving downwards, and plays a role in protecting the needle head from touching bottom damage by matching with a spring (a cleaning needle set spring 90504) in the needle.
The cleaning needle up-and-down movement nut connecting piece 90303 is installed on a cleaning needle up-and-down movement screw rod 90306 connected with the cleaning needle up-and-down movement motor 90302; a cleaning needle up-and-down movement motor 90302 is positioned above the cleaning needle disc 903; the reaction cup rotating disc 902 is controlled to rotate by a reaction cup rotating disc motor 90202, and the reaction cup rotating disc motor 90202 and the shaking up-and-down movement motor 9012 are both located below the base plate 901.
The third manipulator device 1203 clamps the reaction cup which has completed the reaction in the incubation and reaction module 8 to the magnetic separation cleaning module 9, clamps the reaction cup to a preparation position, rotates, adsorbs the magnetic bead compound through the magnetic attraction component 904, then sucks the waste liquid in the reaction cup out through the liquid discharging needles 90503 of the cleaning needle group 90501, simultaneously adds the cleaning liquid into the liquid sucking needles 90502, rotates the reaction cup to a shaking position, continuously rotates after shaking to sequentially suck the liquid discharging and shake through each cleaning needle group 90501, rotates to other cleaning needle groups 90501, sucks the waste liquid, rotates to the substrate liquid adding needle group 906, adds a substrate, rotates to the preparation position after shaking, the third manipulator device 1203 clamps the reaction cup to the incubation and reaction module 8, and waits for the first manipulator device 1201 to clamp the detection module 10.
A cleaning needle assembly 905 and a substrate liquid adding needle assembly 906 are arranged on the cleaning needle disc 903, and the liquid sucking needle 90502, the liquid discharging needle 90503 and the substrate liquid adding needle assembly 906 move up and down under the control of the cleaning needle up-and-down movement motor 90302 to suck, discharge and clean the reaction cup and add a reaction substrate; the reaction cup rotating disc 902 rotates under the control of the reaction cup rotating disc motor 90202, so that the reaction cup is cleaned and shaken up to add the substrate.
The magnetic attraction component 904 arranged on the chassis 901 adsorbs magnetic bead reactants when the reaction cup is cleaned, the shaking component 907 is also arranged, a shaking motor 90702 in the shaking component 907 controls the shaking seat 90701 to do eccentric motion, the cleaning operation in the reaction cup positioned on the shaking seat 90701 is shaken evenly, and the full cleaning is ensured.
The incubation and reaction module 8 of the embodiment is applied to a full-automatic chemiluminescence immunoassay analyzer, as shown in fig. 1-5, the full-automatic chemiluminescence immunoassay analyzer comprises a functional body module 2 arranged on a base 1, the functional body module 2 comprises a sampling needle module 3, a reaction cup loading module 4, a reagent disk module 5, a diluting module 11, a shaking module 7, an incubation and reaction module 8, a magnetic separation cleaning module 9 and a detection module 10, and further comprises a sample management module 6 which is independent from the functional body module 2, the sample management module 6 comprises a sample loading and unloading assembly 601, a sample transmission assembly 602 and a sample sampling carrying assembly 603, wherein the sample loading and unloading assembly 601 is used for loading and unloading a sample rack 604, and the sample transmission assembly 602 is used for transferring the sample rack 604 between the sample loading and unloading assembly 601 and the sample sampling carrying assembly 603; the sampling needle module 3 is used to add the sample at the location of the sample sampling carriage assembly 603 to the incubation and reaction module 8.
As shown in fig. 3, the cuvette loading module 4, the reagent disk module 5, the shaking module 7, the magnetic separation washing module 9 and the detection module 10 are all arranged around the incubation and reaction module 8, wherein the dilution module 11 is arranged at the side of the sampling needle module 3, and the magnetic separation washing module 9 and the detection module 10 are arranged adjacently; the functional body module 2 further includes a manipulator module 12, and manipulator devices 1201, 1202, 1203 (three sets of manipulator devices are provided in this embodiment, and those skilled in the art can increase or decrease according to the needs of the instrument) in the manipulator module 12 are used to transfer cuvettes in the cuvette loading module 4, the shaking module 7, the magnetic separation cleaning module 9, and the detection module 10.
It should be noted that, for the manipulator devices in the cuvette loading module 4, the reagent tray module 5, the shaking module 7, the incubation and reaction module 8, the detection module 10, the dilution module 11, the sampling needle module 3, the sample management module 6 and the manipulator module 12 related to this embodiment, no updated improvement is made, and those skilled in the art can adopt the existing one to realize that they are assembled with the magnetic separation cleaning module 9 in this embodiment and realize that the three-layer structure arrangement fully utilizes the three-dimensional space, reduces the transverse size of the analyzer, reduces the volume, has a compact structure, and improves the cleaning efficiency.
The foregoing illustrates and describes the general principles, features and advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (10)
1. A magnetic separation cleaning module is characterized by comprising a base plate, a reaction cup rotating plate and a cleaning needle plate which are sequentially arranged from bottom to top; the magnetic attraction component is arranged on the base plate and used for adsorbing magnetic bead reactants when the reaction cup is cleaned; the reaction cup rotating disc is used for rotating the reaction cup to a preset position, and a plurality of reaction cup positions are arranged on the reaction cup rotating disc; the cleaning needle disc comprises a cleaning needle assembly and a substrate adding needle assembly, and is used for completing the cleaning and substrate adding operation of the reaction cup.
2. The magnetic separation cleaning module of claim 1, wherein the magnetic assembly comprises a first magnet set and a second magnet set, the first magnet set is used for pre-adsorption, and the second magnet set is used for adsorption of reaction products and magnets; the first magnet group and the second magnet group are both positioned below the reaction cup position.
3. The magnetic separation cleaning module of claim 2, wherein the magnetic separation cleaning module comprises a shaking assembly disposed below the chassis, wherein a shaking seat in the shaking assembly extends out of the chassis and is located below a reaction cup position on the reaction cup rotating disk; the shaking component comprises a shaking motor, and the shaking motor drives the eccentric shaft block component to move so as to drive the shaking seat to shake; the side surface of the shaking seat is provided with a shaking pressure head, and the shaking pressure head is arranged on the chassis through a shaking pressure head bracket.
4. The magnetic separation cleaning module according to claim 3, wherein the shaking seat is connected with a shaking up-and-down motion screw nut connecting block, the shaking up-and-down motion screw nut connecting block is connected with a shaking up-and-down motion screw nut, and a shaking up-and-down motion motor drives the shaking seat to move up and down by driving the shaking up-and-down motion screw nut connecting block to move up and down; and a shaking groove is arranged on the shaking seat.
5. The magnetic separation cleaning module of claim 4, wherein at least two shaking seats are connected to the shaking up and down motion screw nut connecting block, and the shaking up pressure head is semi-spherical.
6. The magnetic separation cleaning module of claim 4, wherein the cleaning dial is controlled to move up and down by a cleaning needle up-and-down motion assembly, the cleaning needle up-and-down motion assembly comprising a cleaning needle up-and-down motion motor, the cleaning needle up-and-down motion motor being connected to the cleaning dial by a cleaning needle up-and-down motion nut connector; the magnetic separation cleaning module is further provided with a guide rod, and the cleaning dial moves up and down along the guide rod.
7. A magnetic separation cleaning module according to claim 6, characterized in that the guide bar is provided with a stopper at a contact position of the cleaning dial and a cleaning dial support plate for supporting the cleaning dial; the cleaning needle assembly comprises a cleaning needle group, the cleaning needle group comprises a liquid suction needle and a liquid discharge needle, and a cleaning needle group spring is further installed in the cleaning needle group.
8. The magnetic separation cleaning module of claim 7, wherein the cleaning pin up-and-down movement nut connector is mounted on a cleaning pin up-and-down movement screw rod connected to the cleaning pin up-and-down movement motor; the cleaning needle up-and-down movement motor is positioned above the cleaning needle disc; the reaction cup rotating disc is controlled to rotate by a reaction cup rotating disc motor, and the reaction cup rotating disc motor and the shaking up-and-down motion motor are both positioned below the base plate.
9. A magnetic separation cleaning module according to any one of claims 1 to 8, which is adapted to a full-automatic chemiluminescent immunoassay analyzer comprising a functional body module disposed on a base, the functional body module comprising a sampling needle module, a reaction cup loading module, a reagent disk module, a diluting module, a shaking module, an incubation and reaction module, a magnetic separation cleaning module, a detection module, and a sample management module independent of the functional body module.
10. The magnetic separation cleaning module of claim 9, wherein the reaction cup loading module, reagent tray module, shaking module, magnetic separation cleaning module and detection module are all arranged around the incubation and reaction module, wherein the dilution module is disposed at the side of the sampling needle module, and the magnetic separation cleaning module and the detection module are disposed adjacently; the functional main body module further comprises a mechanical arm module, and a mechanical arm device in the mechanical arm module is used for transferring reaction cups positioned in the reaction cup loading module, the shaking module, the magnetic separation cleaning module and the detection module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222948056.2U CN218885938U (en) | 2022-11-07 | 2022-11-07 | Magnetic separation cleaning module |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202222948056.2U CN218885938U (en) | 2022-11-07 | 2022-11-07 | Magnetic separation cleaning module |
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| CN218885938U true CN218885938U (en) | 2023-04-18 |
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| CN202222948056.2U Active CN218885938U (en) | 2022-11-07 | 2022-11-07 | Magnetic separation cleaning module |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116786504A (en) * | 2023-08-29 | 2023-09-22 | 江苏三联生物工程股份有限公司 | Magnetic bead cleaning and separating device and method for chemiluminescent immunoassay analyzer |
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2022
- 2022-11-07 CN CN202222948056.2U patent/CN218885938U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116786504A (en) * | 2023-08-29 | 2023-09-22 | 江苏三联生物工程股份有限公司 | Magnetic bead cleaning and separating device and method for chemiluminescent immunoassay analyzer |
| CN116786504B (en) * | 2023-08-29 | 2023-11-03 | 江苏三联生物工程股份有限公司 | Magnetic bead cleaning and separating device and method for chemiluminescent immunoassay analyzer |
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